公开(公告)号：US11071701B2

公开(公告)日：2021-07-27

申请号：US16310240

申请日：2016-06-30

Applicant: Symrise AG

Inventor： Marielle Le Maire ,  Imke Meyer ,  Gabriele Vielhaber ,  Gerhard Schmaus

IPC: A61K8/34 ,  A61Q17/04 ,  A61Q19/02

Abstract: The present invention belongs to the fields of pharmaceuticals and cosmetics, and concerns on the one hand a medicament for the inhibition of and refers also on the cosmetic, non-therapeutic use for the treatment of hyperpigmentation, particularly induced by sun light radiation, preferably induced by visible light radiation.

公开(公告)号：US10357447B2

公开(公告)日：2019-07-23

申请号：US15577073

申请日：2016-05-25

Applicant: Symrise AG

Inventor： Jean Krutmann ,  Imke Meyer ,  William Johncock ,  Gerhard Schmaus ,  Marielle le Maire

IPC: A61Q5/00 ,  A61Q17/04 ,  A61K8/97 ,  A61K8/9783 ,  A61K8/35 ,  A61K8/49 ,  A61Q17/00 ,  A61K8/9794 ,  A61K8/9789 ,  A61K36/28 ,  A61K36/9068

Abstract: Suggested is a cosmetic composition comprising an anti-pollution agent selected from the group consisting of sclareolide, ginger root CO2 extract, E/Z-2-benzylindene-5,6-dimethoxy-3,3-dimethylindan-1-one, purple coneflower pressed juice or mixtures thereof, in a working amount sufficient for (a) reducing or preventing air pollution induced gene expression, and/or (b) reducing or preventing a gene expression induced or inducible by polycyclic aromatic hydrocarbons, and/or (c) reducing or preventing air pollution-induced or air pollution-inducible skin damage.

公开(公告)号：US20180303735A1

公开(公告)日：2018-10-25

申请号：US15961260

申请日：2018-04-24

Applicant: Symrise AG

Inventor： Martina Herrmann ,  Gerhard Schmaus

IPC: A61K8/49 ,  A61P17/02 ,  A61Q19/00 ,  A61Q19/08 ,  A61Q5/00 ,  A61Q11/00 ,  A61K8/35

CPC classification number: A61K8/4973 ,  A61K8/35 ,  A61P17/02 ,  A61Q5/00 ,  A61Q11/00 ,  A61Q19/00 ,  A61Q19/007 ,  A61Q19/08

Abstract: A cosmetic composition, including compounds of formula (I) in which R and R′ independently of one another denote hydrogen, hydroxyl, a linear or branched OC1-C4-alkyl group, or optionally R and R′ form together a methylenedioxy group resulting in a 3,4-methylendioxyphenyl residue and R″ denotes a linear or branched C1-C9 alkyl group or A, in which A denotes with X, Y and Z being independently of one another hydrogen, hydroxyl, an linear or branched C1-C4-alkyl group, or a linear or branched OC1-C4-alkyl group.

公开(公告)号：US09585388B2

公开(公告)日：2017-03-07

申请号：US13668560

申请日：2012-11-05

Applicant: SYMRISE AG

Inventor： Ravikumar Pillai ,  Antje Köhler ,  Gerhard Schmaus

IPC: A61Q15/00 ,  A61K8/34 ,  A01N31/14 ,  A01N31/02 ,  A61K31/047 ,  A61K31/085 ,  A61Q17/00 ,  A61K9/00 ,  A23L3/3481 ,  A61Q1/02 ,  A61Q5/02 ,  A61Q17/04 ,  A61Q19/00

CPC classification number: A01N31/14 ,  A01N31/02 ,  A23L3/3481 ,  A61K8/34 ,  A61K8/345 ,  A61K9/0014 ,  A61K31/047 ,  A61K31/085 ,  A61K2800/524 ,  A61K2800/5922 ,  A61Q1/02 ,  A61Q5/02 ,  A61Q15/00 ,  A61Q17/005 ,  A61Q17/04 ,  A61Q19/00 ,  A01N2300/00 ,  A61K2300/00

Abstract: The invention relates to synergistically effective ternary antimicrobial mixtures.

Abstract translation: 本发明涉及协同有效的三元抗微生物混合物。

公开(公告)号：US10780043B2

公开(公告)日：2020-09-22

申请号：US15577433

申请日：2016-05-25

Applicant: Symrise AG

Inventor： Jean Krutmann ,  Imke Meyer ,  William Johncock ,  Gerhard Schmaus ,  Marielle le Maire

IPC: A61K8/9783 ,  A61Q17/00 ,  A61K8/35 ,  A61K8/49 ,  A61K8/97 ,  A61K8/9794 ,  A61K8/9789 ,  A61Q17/04 ,  A61K36/28 ,  A61K36/9068 ,  A61Q5/00

Abstract: Suggested is a cosmetic composition comprising an anti-pollution agent selected from the group consisting of ginger root C02 extract, E/Z-2-benzylindene-5,6-dimethoxy-3,3-dimethylindan-1-one, sclareolide, purple coneflower pressed juice or mixtures thereof, in a working amount sufficient for (a) reducing or preventing air pollution induced gene expression, and/or (b) reducing or preventing a gene expression induced or inducible by polycyclic aromatic hydrocarbons, and/or (c) reducing or preventing air pollution-induced or air pollution-inducible skin damage.

公开(公告)号：US10780042B2

公开(公告)日：2020-09-22

申请号：US15576484

申请日：2016-05-24

Applicant: Symrise AG

Inventor： Jean Krutmann ,  Imke Meyer ,  William Johncock ,  Gerhard Schmaus ,  Marielle le Maire ,  Martina Herrmann

IPC: A61K8/9783 ,  A61Q17/00 ,  A61K8/35 ,  A61K8/49 ,  A61K8/97 ,  A61K8/9794 ,  A61K8/9789 ,  A61Q17/04 ,  A61K36/28 ,  A61K36/9068 ,  A61Q5/00

Abstract: Suggested is a cosmetic composition comprising an anti-pollution agent selected from the group consisting of E/Z-2-benzylindene-5,6-dimethoxy-3,3-dimethylindan-1-one, sclareolide, purple coneflower pressed juice, ginger root CO2 extract or mixtures thereof, in a working amount sufficient for (a) reducing or preventing air pollution induced gene expression, and/or (b) reducing or preventing a gene expression induced or inducible by polycyclic aromatic hydrocarbons, and/or (c) reducing or preventing air pollution-induced or air pollution-inducible skin damage.

公开(公告)号：US20180185301A1

公开(公告)日：2018-07-05

申请号：US15736494

申请日：2016-06-19

Applicant: Symrise AG

Inventor： Gerhard Schmaus ,  Sabine Lange

IPC: A61K31/08 ,  A61K31/25 ,  A61K8/39 ,  A61Q5/00 ,  A61Q5/12 ,  A61Q15/00 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/02

CPC classification number: A61K31/08 ,  A61K8/33 ,  A61K8/39 ,  A61K31/25 ,  A61K31/765 ,  A61K45/06 ,  A61K2800/75 ,  A61Q5/006 ,  A61Q5/12 ,  A61Q15/00 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/004 ,  A61Q19/005 ,  A61Q19/02 ,  A61K2300/00

Abstract: Suggested are compositions comprising or consisting of specific polyalkylene glycol derivative as pharmaceutical actives for preventing, treating and/or curing itchy conditions of human skin and scalp, and/or providing a PAR-2 antagonistic effect to human skin and scalp.

公开(公告)号：US20180153783A1

公开(公告)日：2018-06-07

申请号：US15576484

申请日：2016-05-24

Applicant: Symrise AG

Inventor： Jean Krutmann ,  Imke Meyer ,  William Johncock ,  Gerhard Schmaus ,  Marielle le Maire ,  Martina Herrmann

IPC: A61K8/35 ,  A61K8/49 ,  A61K8/9794 ,  A61K8/9789 ,  A61Q17/00

Abstract: Suggested is a cosmetic composition comprising an anti-pollution agent selected from the group consisting of E/Z-2-benzylindene-5,6-dimethoxy-3,3-dimethylindan-1-one, sclareolide, purple coneflower pressed juice, ginger root CO2 extract or mixtures thereof, in a working amount sufficient for (a) reducing or preventing air pollution induced gene expression, and/or (b) reducing or preventing a gene expression induced or inducible by polycyclic aromatic hydrocarbons, and/or (c) reducing or preventing air pollution-induced or air pollution-inducible skin damage.

公开(公告)号：US12193441B2

公开(公告)日：2025-01-14

申请号：US17279812

申请日：2018-08-27

Applicant: SYMRISE AG

Inventor： Manuel Pesaro ,  Bernd Hölscher ,  Gerhard Schmaus ,  Antje Köhler

IPC: A01N35/04 ,  A23L3/3499 ,  A61K8/34 ,  A61Q17/00 ,  C11D3/48 ,  A61C5/02 ,  A61Q5/06 ,  A61Q5/12 ,  A61Q11/00 ,  A61Q15/00 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/10

Abstract: Suggested is a synergistic antimicrobial mixture comprising a hydroxyacetophenone and one additional antimicrobial agent. The mixture is particular useful for fighting Aspergillus brasiliensis.

公开(公告)号：US12128129B2

公开(公告)日：2024-10-29

申请号：US17254347

申请日：2019-06-26

Applicant: SYMRISE AG ,  PROBI AB

Inventor： Manuel Pesaro ,  Dominik Stuhlmann ,  Lisa Garbe ,  Gerhard Schmaus ,  Kerstin Holmgren ,  Niklas Larsson

IPC: A61K8/99 ,  A61G19/00 ,  A61K8/02 ,  A61K9/14 ,  A61K35/747 ,  A61P17/00 ,  A61P29/00 ,  A61Q19/00

CPC classification number: A61K8/99 ,  A61G19/00 ,  A61K8/0225 ,  A61K9/14 ,  A61K35/747 ,  A61P17/00 ,  A61P29/00

Abstract: The present invention relates to microorganisms for use in the treatment and/or prevention of skin conditions by topical application. In particular, the microorganisms are for use in the treatment and/or prevention of loss of skin barrier function, inflammatory conditions and/or growth of pathogenic microorganism. The invention further relates to pharmaceutical or cosmetic compositions or products comprising the microorganisms Provided is also a cosmetic use of the microorganisms or compositions for application on the skin and a cosmetic method, in particular to improve the appearance of the skin.