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    System and method for prevention of radiocontrast induced nephropathy
    1.
    发明申请
    System and method for prevention of radiocontrast induced nephropathy 审中-公开
    用于预防放射性对照诱导的肾病的系统和方法

    公开(公告)号：US20070213686A1

    公开(公告)日：2007-09-13

    申请号：US11347008

    申请日：2006-02-03

    申请人： Vandana Mathur ,  Craig Ball ,  Jeffrey Elkins ,  Harry Goodson ,  Samir Patel

    发明人： Vandana Mathur ,  Craig Ball ,  Jeffrey Elkins ,  Harry Goodson ,  Samir Patel

    IPC分类号： A61B19/00

    CPC分类号： A61M5/1723 ,  A61B90/00 ,  A61B2017/22082 ,  A61M5/007 ,  A61M25/0068 ,  A61M2005/1403 ,  A61M2025/0037 ,  A61M2025/1045

    摘要： An apparatus and method particularly useful in treatments and therapies directed at the kidneys such as the prevention of radiocontrast nephropathy (RCN) arising from diagnostic procedures using iodinated contrast materials. A series of treatment schemes are provided based upon local therapeutic agent delivery to the kidneys that can be used as a prophylactic treatment for patients undergoing interventional procedures that have been identified as being at an elevated risk for developing RCN as well as for low risk patients. The methods may include pre-exposure and post contrast exposure treatments alone or in combination with the local delivery of therapeutic agents to the kidneys. Among the agents identified for such treatments are normal saline and the vasodilators papaverine and fenoldopam mesylate and appropriate dosing is provided.

    摘要翻译： 特别适用于针对肾脏的治疗和疗法的装置和方法，例如使用碘化造影剂的诊断程序引起的放射性对比肾病（RCN）的预防。 提供了一系列基于局部治疗剂递送到肾脏的治疗方案，其可用作对已经被鉴定为发展RCN和低风险患者的高风险的介入手术的患者的预防性治疗。 所述方法可以包括单独的暴露前曝光和造影后处理，或与治疗剂局部递送到肾脏的方法。 鉴定用于这种治疗的药剂是生理盐水，并且提供了血管扩张剂罂粟碱和甲磺酸芬诺多胺，并提供适当的给药。

    Systems and methods for performing bi-lateral interventions or diagnosis in branched body lumens
    2.
    发明申请
    Systems and methods for performing bi-lateral interventions or diagnosis in branched body lumens 失效
    在分支体内进行双侧干预或诊断的系统和方法

    公开(公告)号：US20060149350A1

    公开(公告)日：2006-07-06

    申请号：US11295735

    申请日：2005-12-05

    申请人： Samir Patel ,  Harry Goodson ,  Jeffrey Elkins ,  Craig Ball ,  Vandana Mathur

    发明人： Samir Patel ,  Harry Goodson ,  Jeffrey Elkins ,  Craig Ball ,  Vandana Mathur

    IPC分类号： A61F2/06

    CPC分类号： A61F2/954 ,  A61B2017/00331 ,  A61B2017/22068 ,  A61B2017/22071 ,  A61F2/013 ,  A61F2/958 ,  A61F2002/065 ,  A61F2002/821 ,  A61F2002/9517 ,  A61F2002/9528 ,  A61M25/1002

    摘要： Bifurcated delivery assemblies provide bilateral access to first and second branch lumens extending from a main body space or lumen in a patient. One or more interventional devices are combined with the delivery assemblies for delivery s into one or both of the branch lumens. Bilateral renal stenting or embolic protection procedures are performed using the combination delivery/interventional device assemblies. Fluids may also be injected or aspirated from the assemblies. A bifurcated catheter has a first fluid port located on one bifurcation branch, a second fluid port located on a second branch of the bifurcation, and a third fluid port positioned so as to be located within a vena cava when the first and second ports are positioned bilaterally within first and second renal veins.

    摘要翻译： 分叉输送组件提供从患者的主体空间或内腔延伸的第一和第二分支腔的双向通路。 将一个或多个介入装置与输送组件组合以用于输送到分支腔中的一个或两个。 使用组合递送/介入装置组件进行双侧肾支架置入或栓塞保护程序。 流体也可以从组件注入或吸出。 分叉导管具有位于一个分叉分支上的第一流体端口，位于分叉的第二分支上的第二流体端口和位于第一和第二端口定位的位于腔静脉内的第三流体端口 在第一和第二肾静脉内双侧。

    VASCULAR SHEATH WITH VARIABLE LUMEN CONSTRUCTION
    3.
    发明申请
    VASCULAR SHEATH WITH VARIABLE LUMEN CONSTRUCTION 审中-公开
    具有可变的建筑结构的血管

    公开(公告)号：US20070167913A1

    公开(公告)日：2007-07-19

    申请号：US11548565

    申请日：2006-10-11

    申请人： Jeffrey Elkins ,  Harry Goodson ,  Craig Ball ,  Aurelio Valencia ,  Samir Patel ,  Neema Hekmat

    发明人： Jeffrey Elkins ,  Harry Goodson ,  Craig Ball ,  Aurelio Valencia ,  Samir Patel ,  Neema Hekmat

    IPC分类号： A61M5/178 ,  A61F2/06 ,  A61M31/00

    CPC分类号： A61M25/0662 ,  A61F2/07 ,  A61F2002/065 ,  A61M25/0668 ,  A61M2025/0024 ,  A61M2025/0183 ,  A61M2025/0188 ,  A61M2025/0681

    摘要： A system for delivering a renal treatment and a peripheral treatment includes a renal catheter, a peripheral catheter, and an introducer sheath having first and second lumens. The first lumen is configured to receive the renal catheter and is sized to extend from a patient insertion site to a femoral or iliac artery location near or distal to a patient aortic branch. The second lumen is configured to receive the peripheral catheter and is sized to extend from the patient insertion site to an opposite femoral or iliac artery location near or distal to the patient aortic branch. A method of delivering a renal treatment and a peripheral treatment includes positioning an introducer sheath in an iliac artery, advancing a renal catheter and a peripheral catheter through the introducer sheath, where the renal catheter is separated from the peripheral catheter within the introducer sheath by a flap.

    摘要翻译： 用于递送肾脏治疗和外周治疗的系统包括肾导管，外周导管和具有第一和第二腔的导引鞘。 第一管腔被配置为接纳肾导管，其尺寸设计成从患者插入位置延伸到患者主动脉分支附近或远侧的股骨或髂动脉位置。 第二管腔构造成接收外周导管，其尺寸设计成从患者插入位置延伸到患者主动脉分支附近或远侧的相对的股骨或髂动脉位置。 递送肾脏治疗和周边治疗的方法包括将引导器鞘定位在髂动脉中，使肾导管和外周导管穿过导引鞘，其中肾导管与导引鞘内的周围导管分开一个 皮瓣

    Method and apparatus for intra-aortic substance delivery to a branch vessel
    6.
    发明申请
    Method and apparatus for intra-aortic substance delivery to a branch vessel 有权
    用于主动脉内物质输送到分支血管的方法和装置

    公开(公告)号：US20050245882A1

    公开(公告)日：2005-11-03

    申请号：US11084434

    申请日：2005-03-18

    申请人： Jeffrey Elkins ,  Aurelio Valencia ,  Samir Patel ,  Ricardo Aboytes ,  Harry Goodson ,  Craig Ball

    发明人： Jeffrey Elkins ,  Aurelio Valencia ,  Samir Patel ,  Ricardo Aboytes ,  Harry Goodson ,  Craig Ball

    IPC分类号： A61M20060101 ,  A61M5/31 ,  A61M25/00 ,  A61M37/00

    CPC分类号： A61M25/0068 ,  A61M25/00 ,  A61M25/0041 ,  A61M25/007 ,  A61M25/0071 ,  A61M25/0074 ,  A61M25/0075 ,  A61M25/0082 ,  A61M39/06 ,  A61M2025/0073 ,  A61M2025/105

    摘要： A renal flow system injects a volume of fluid agent into a location within an abdominal aorta in a manner that flows bi-laterally into each of two renal arteries via their respectively spaced ostia along the abdominal aorta wall. A local injection assembly includes two injection members, each having an injection port that couples to a source of fluid agent externally of the patient. The injection ports may be positioned with an outer region of blood flow along the abdominal aorta wall perfusing the two renal arteries. A flow isolation assembly may isolate flow of the injected agent within the outer region and into the renals. The injection members are delivered to the location in a first radially collapsed condition, and bifurcate across the aorta to inject into the spaced renal ostia. A delivery catheter for upstream interventions is used as a chassis to deliver a bilateral local renal injection assembly to the location within the abdominal aorta.

    摘要翻译： 肾流系统以一定的方式将一定体积的流体药剂注入腹主动脉内的一个位置，这两种方式通过沿着腹主动脉壁的分别间隔开的两个肾动脉双向流入两个肾动脉。 局部注射组件包括两个注射构件，每个注射构件具有连接到病人外部的流体剂源的注射口。 注射口可以沿着灌注两个肾动脉的腹主动脉壁的外侧血流区域定位。 流动隔离组件可以隔离外部区域内的注射药剂流入肾脏。 注射构件在第一径向折叠状态下被输送到该位置，并且跨越主动脉分叉以注入间隔开的肾口。 用于上游干预的输送导管用作底架以将双侧局部肾注射组件递送至腹主动脉内的位置。

    Apparatus and method for inserting an intra-aorta catheter through a delivery sheath
    10.
    发明申请
    Apparatus and method for inserting an intra-aorta catheter through a delivery sheath 有权
    用于通过输送鞘插入主动脉内导管的装置和方法

    公开(公告)号：US20050245892A1

    公开(公告)日：2005-11-03

    申请号：US11084295

    申请日：2005-03-18

    申请人： Jeffrey Elkins ,  Harry Goodson ,  Mark Maguire ,  Aurelio Valencia ,  Samir Patel

    发明人： Jeffrey Elkins ,  Harry Goodson ,  Mark Maguire ,  Aurelio Valencia ,  Samir Patel

    IPC分类号： A61M25/00 ,  A61M25/01 ,  A61M25/06 ,  A61M31/00

    CPC分类号： A61M25/0043 ,  A61M25/0662 ,  A61M39/06

    摘要： An introducer system delivers therapy locally to a renal system in a patient. A proximal coupler assembly is coupled to an introducer sheath that delivers multiple devices simultaneously into a location within an abdominal aorta associated with first and second renal artery ostia. The coupler assembly has a network of branch lumens arranged to allow for smooth slideable engagement of multiple coupled devices without substantial interference therebetween. A first branch lumen typically introduces a percutaneous translumenal interventional device such as an angiography or guiding catheter into the introducer sheath and is substantially aligned with a longitudinal axis of the sheath. One or more other branch lumen are off-axis from the longitudinal axis by about 30 degrees or less and introduce components of a bilateral renal delivery assembly into the introducer sheath in conjunction with the other device. Novel insertion devices are provided to coordinate the coupling of the multiple devices.

    摘要翻译： 导引器系统将局部给予患者的肾系统治疗。 近端联接器组件联接到导引器鞘，其将多个装置同时输送到与第一和第二肾动脉口相关联的腹主动脉内的位置。 耦合器组件具有布置成允许多个耦合器件的平滑可滑动接合而没有实质干涉的分支腔的网络。 第一分支腔通常将经皮腔内介入装置（例如血管造影或引导导管）引入导引器鞘并且基本上与护套的纵向轴线对准。 一个或多个其它分支腔从纵向轴线偏离约30度或更小，并且将双侧肾递送组件的组件与另一装置一起引入导引鞘中。 提供了新的插入装置来协调多个装置的耦合。