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1.发明授权公开(公告)号：US06180584B2
公开(公告)日：2001-01-30
申请号：US09248861
申请日：1999-02-11
IPC分类号： C11D348
CPC分类号： A01N47/44 , A01N25/10 , A01N25/24 , A01N59/16 , C02F1/505 , C02F2209/001 , A01N2300/00 , A01N25/02
摘要： The present invention relates to a composition that, when applied to a substrate, forms an adherent, transparent, water insoluble polymeric film on the substrate surface that provides sustained antimicrobial disinfecting action for prolonged periods, without the necessity for reapplication. The coating provides surface disinfecting action by a contact-killing mechanism, and does not release its components into contacting solutions at levels that would result in solution disinfection. The polymeric film formed by the composition of the invention can be removed by treatment with dilute alcoholic base.
摘要翻译： 本发明涉及一种组合物，当应用于基材时，在基材表面上形成粘附的，透明的水不溶性聚合物膜，其提供持续的抗微生物消毒作用，延长时间，而不需要重新施用。 涂层通过接触杀伤机制提供表面消毒作用，并且不会将其组分以导致溶液消毒的水平释放到接触溶液中。 通过本发明的组合物形成的聚合物膜可以通过用稀醇基处理除去。
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公开(公告)号：US5490938A
公开(公告)日：1996-02-13
申请号：US170510
申请日：1993-12-20
IPC分类号： A01N25/24 , A01N25/34 , A01N47/44 , A01N59/16 , A61J1/14 , A61J1/20 , A61L2/16 , B01D39/00 , B01D39/16 , B01D39/20 , B01D67/00 , B01D69/02 , B01D69/12 , B01D71/02 , B01D61/00 , A61B19/00 , B67D5/58
CPC分类号： B01D67/0088 , A01N25/24 , A01N25/34 , A01N47/44 , A01N59/16 , A61L2/16 , B01D39/00 , B01D39/16 , B01D39/2027 , B01D67/0069 , B01D67/0072 , B01D67/009 , B01D69/02 , B01D69/12 , B01D71/022 , B05B11/047 , B65D47/18 , A61J1/145 , A61J1/1456 , A61J1/1468 , B01D2239/0442 , B01D2239/0478 , B01D2323/02 , B01D2325/48 , B65D81/24
摘要： A liquid dispenser for dispensing sterile liquid comprising a container for storing the sterile liquid, a nozzle assembly mounted on the container, and a filter which has at least one surface and a plurality of its pores coated with a metallic material, e.g., a metal or metal oxide or metal salt, that is bacteriostatic or bacteriocidal, is described. The metal coated filter, methods for coating the filter, and methods for using the liquid dispenser are also provided.
摘要翻译： 一种用于分配无菌液体的液体分配器，其包括用于存储无菌液体的容器，安装在容器上的喷嘴组件和具有至少一个表面和多个其孔的涂层的过滤器，所述金属材料例如金属或 描述了抑菌或杀菌的金属氧化物或金属盐。 还提供了金属涂层过滤器，涂覆过滤器的方法和使用液体分配器的方法。
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公开(公告)号：US6030632A
公开(公告)日：2000-02-29
申请号：US151866
申请日：1998-09-11
IPC分类号： B65D83/00 , A01N25/24 , A01N25/34 , A01N47/44 , A01N59/16 , A61J1/05 , A61J1/14 , A61J1/20 , A61L2/16 , B01D39/00 , B01D39/16 , B01D39/20 , B01D67/00 , B01D69/02 , B01D69/12 , B01D71/02 , A01N25/08
CPC分类号： B01D67/0088 , A01N25/24 , A01N25/34 , A01N47/44 , A01N59/16 , A61L2/16 , B01D39/00 , B01D39/16 , B01D39/1623 , B01D39/1692 , B01D67/0069 , B01D67/0072 , B01D67/0079 , B01D67/009 , B01D69/02 , B01D69/12 , B01D69/148 , B01D71/022 , B82Y30/00 , A61J1/145 , A61J1/1456 , A61J1/1468 , B01D2239/0442 , B01D2239/0471 , B01D2239/0478 , B01D2323/02 , B01D2323/04 , B01D2325/38 , B01D2325/48
摘要： An antimicrobial material comprising an antimicrobial metallic material and a biguanide polymer reacted with a crosslinker to form an adduct is described. Both freestanding antimicrobial materials and antimicrobial films are provided. The antimicrobial material does not release biocidal levels of leachables into a contacting solution.
摘要翻译： 描述了包含抗微生物金属材料和与交联剂反应形成加合物的双胍聚合物的抗微生物材料。 提供了独立的抗菌材料和抗微生物膜。 抗微生物材料不会将杀生物等级的可浸出物释放到接触溶液中。
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公开(公告)号：US5817325A
公开(公告)日：1998-10-06
申请号：US742580
申请日：1996-10-28
CPC分类号： A01N47/44 , A01N25/34 , A01N59/16 , B01D39/2037 , B01D2239/0442 , B01D2239/0471 , B01D2239/0478 , B01D2239/086
摘要： Contact killing antimicrobial articles, devices and formulations are described which kill microorganisms on contact. The articles, devices or formulations contain a non-leaching antimicrobial material which is a unique combination of an organic matrix having biocidal metallic materials non-leachably associated with the matrix. The antimicrobial material may used to form an antimicrobial coating or layer on a surface of the article or device, or may be dispersed in a vehicle or carrier to form a topical antiseptic or disinfectant, or solid shape having contact killing antimicrobial properties. When a microorganism contacts the article, device, or formulation, the biocidal metallic material is transferred to the microorganism in amounts sufficient to kill it.
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公开(公告)号：US5681468A
公开(公告)日：1997-10-28
申请号：US599810
申请日：1996-02-12
IPC分类号： A01N25/24 , A01N25/34 , A01N47/44 , A01N59/16 , A61J1/14 , A61J1/20 , A61L2/16 , B01D39/00 , B01D39/16 , B01D39/20 , B01D67/00 , B01D69/02 , B01D69/12 , B01D71/02
CPC分类号： B01D67/0088 , A01N25/24 , A01N25/34 , A01N47/44 , A01N59/16 , A61L2/16 , B01D39/00 , B01D39/16 , B01D39/2027 , B01D67/0069 , B01D67/0072 , B01D67/009 , B01D69/02 , B01D69/12 , B01D71/022 , B05B11/047 , B65D47/18 , A61J1/145 , A61J1/1456 , A61J1/1468 , B01D2239/0442 , B01D2239/0478 , B01D2323/02 , B01D2325/48 , B65D81/24
摘要： A liquid dispenser for dispensing sterile liquid comprising a container for storing the sterile liquid, a nozzle assembly mounted on the container, and a filter which has at least one surface and a plurality of its pores coated with a metallic material, e.g., a metal or metal oxide or metal salt, that is bacteriostatic or bacteriocidal, is described. The metal coated filter, methods for coating the filter, and methods for using the liquid dispenser are also provided.
摘要翻译： 一种用于分配无菌液体的液体分配器，其包括用于存储无菌液体的容器，安装在容器上的喷嘴组件和具有至少一个表面和多个其孔的涂层的过滤器，所述金属材料例如金属或 描述了抑菌或杀菌的金属氧化物或金属盐。 还提供了金属涂层过滤器，涂覆过滤器的方法和使用液体分配器的方法。
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公开(公告)号：US07288264B1
公开(公告)日：2007-10-30
申请号：US09617566
申请日：2000-07-17
CPC分类号： A01N59/16 , A01N25/10 , A01N2300/00
摘要： Contact killing antimicrobial articles, devices and formulations are described which kill microorganisms on contact. The articles, devices or formulations contain a non-leaching antimicrobial material which is a unique combination of an organic matrix having biocidal metallic materials non-leachably associated with the matrix. The antimicrobial material may used to form an antimicrobial coating or layer on a surface of the article or device, or may be dispersed in a vehicle or carrier to form a topical antiseptic or disinfectant, or solid shape having contact killing antimicrobial properties. When a microorganism contacts the article, device, or formulation, the biocidal metallic material is transferred to the microorganism in amounts sufficient to kill it.
摘要翻译： 描述了杀死接触杀伤微生物的抗微生物制品，装置和制剂的接触。 制品，装置或制剂含有非浸出抗菌材料，其是具有不可浸出与基质相关的杀生物金属材料的有机基质的独特组合。 抗微生物材料可以用于在制品或装置的表面上形成抗微生物涂层或层，或者可以分散在载体或载体中以形成具有接触杀伤抗微生物性质的局部消毒剂或消毒剂或固体形式。 当微生物与制品，装置或制剂接触时，杀生物金属材料以足以将其杀死的量转移到微生物中。
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公开(公告)号：US06264936B1
公开(公告)日：2001-07-24
申请号：US09151878
申请日：1998-09-11
IPC分类号： A01N2510
CPC分类号： B01D39/00 , A01N25/24 , A01N25/34 , A01N47/44 , A01N59/16 , A61J1/145 , A61J1/1456 , A61J1/1468 , A61L2/16 , B01D39/16 , B01D67/0088 , B01D67/009 , B01D69/02 , B01D69/12 , B01D69/141 , B01D71/022 , B01D2239/0471 , B01D2323/12 , B01D2325/48 , A01N2300/00
摘要： An antimicrobial material is described which can be used to form on the surface on a substrate a non-leaching antimicrobial coating or layer which kills microorganisms on contact. The non-leaching antimicrobial coating or layer is a unique combination of an organic matrix immobilized on the surface of the substrate to having biocidal metallic materials non-leachably associated with the matrix. When a microorganism contacts the coating or layer, the biocidal metallic material is transferred to the microorganism in amounts sufficient to kill it. Methods of applying the coating or layer to a substrate also are provided.
摘要翻译： 描述了一种抗微生物材料，其可用于在基底上在表面上形成非浸出抗微生物涂层或在接触时杀死微生物的层。 非浸出抗微生物涂层或层是固定在基底表面上的具有不可浸出与基质相关的杀生物金属材料的有机基质的独特组合。 当微生物接触涂层或层时，杀生物金属材料以足以使其杀死的量转移到微生物中。 还提供了将涂层或层施加到基底的方法。
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公开(公告)号：US06126931A
公开(公告)日：2000-10-03
申请号：US151495
申请日：1998-09-11
CPC分类号： A01N47/44 , A01N25/34 , A01N59/16 , B01D39/2037 , B01D2239/0442 , B01D2239/0471 , B01D2239/0478 , B01D2239/086
摘要： Contact killing antimicrobial articles, devices and formulations are described which kill microorganisms on contact. The articles, devices or formulations contain a non-leaching antimicrobial material which is a unique combination of an organic matrix having biocidal metallic materials non-leachably associated with the matrix. The antimicrobial material may used to form an antimicrobial coating or layer on a surface of the article or device, or may be dispersed in a vehicle or carrier to form a topical antiseptic or disinfectant, or solid shape having contact killing antimicrobial properties. When a microorganism contacts the article, device, or formulation, the biocidal metallic material is transferred to the microorganism in amounts sufficient to kill it.
摘要翻译： 描述了杀死接触杀伤微生物的抗微生物制品，装置和制剂的接触。 制品，装置或制剂含有非浸出抗菌材料，其是具有不可浸出与基质相关的杀生物金属材料的有机基质的独特组合。 抗微生物材料可以用于在制品或装置的表面上形成抗微生物涂层或层，或者可以分散在载体或载体中以形成具有接触杀伤抗微生物性质的局部消毒剂或消毒剂或固体形式。 当微生物与制品，装置或制剂接触时，杀生物金属材料以足以将其杀死的量转移到微生物中。
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公开(公告)号：US5869073A
公开(公告)日：1999-02-09
申请号：US663269
申请日：1996-12-13
IPC分类号： B65D83/00 , A01N25/24 , A01N25/34 , A01N47/44 , A01N59/16 , A61J1/05 , A61J1/14 , A61J1/20 , A61L2/16 , B01D39/00 , B01D39/16 , B01D39/20 , B01D67/00 , B01D69/02 , B01D69/12 , B01D71/02 , A01N25/32
CPC分类号： B01D67/0088 , A01N25/24 , A01N25/34 , A01N47/44 , A01N59/16 , A61L2/16 , B01D39/00 , B01D39/16 , B01D39/1623 , B01D39/1692 , B01D67/0069 , B01D67/0072 , B01D67/0079 , B01D67/009 , B01D69/02 , B01D69/12 , B01D69/148 , B01D71/022 , B82Y30/00 , A61J1/145 , A61J1/1456 , A61J1/1468 , B01D2239/0442 , B01D2239/0471 , B01D2239/0478 , B01D2323/02 , B01D2323/04 , B01D2325/38 , B01D2325/48
摘要： A liquid composition for applying a non-leachable antimicrobial coating on a surface. The liquid composition consists of a solution, dispersion or suspension of a biguanide polymer reacted with a cross-linking agent to form an adduct, and an antimicrobial metal material. The resulting antimicrobial coating does not release biocidal levels of leachables into surrounding solution.
摘要翻译： PCT No.PCT / US94 / 14636 Sec。 371日期1996年12月13日第 102（e）日期1996年12月13日PCT 1994年12月19日PCT公布。 出版物WO95 / 17152 日期1995年7月29日用于在表面上施加不可浸出的抗微生物涂层的液体组合物。 液体组合物由与交联剂反应形成加合物的双胍聚合物的溶液，分散体或悬浮液以及抗微生物金属材料组成。 所得抗微生物涂层不会将可浸出物的杀生物水平释放到周围溶液中。
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公开(公告)号：US5849311A
公开(公告)日：1998-12-15
申请号：US736823
申请日：1996-10-28
IPC分类号： A01N25/24 , A01N25/34 , A01N47/44 , A01N59/16 , A61J1/14 , A61L2/16 , B01D39/00 , B01D39/16 , B01D39/20 , B01D67/00 , B01D69/02 , B01D69/12 , B01D71/02 , A01N25/32
CPC分类号： B01D39/00 , A01N25/24 , A01N25/34 , A01N47/44 , A01N59/16 , A61L2/16 , B01D39/16 , B01D67/0088 , B01D67/009 , B01D69/02 , B01D69/12 , B01D69/141 , B01D71/022 , A61J1/145 , A61J1/1456 , A61J1/1468 , B01D2239/0471 , B01D2323/12 , B01D2325/48
摘要： An antimicrobial material is described which can be used to form on the surface on a substrate a non-leaching antimicrobial coating or layer which kills microorganisms on contact. The non-leaching antimicrobial coating or layer is a unique combination of an organic matrix immobilized on the surface of the substrate to having biocidal metallic materials non-leachably associated with the matrix. When a microorganism contacts the coating or layer, the biocidal metallic material is transferred to the microorganism in amounts sufficient to kill it.
摘要翻译： 描述了一种抗微生物材料，其可用于在基底上在表面上形成非浸出抗微生物涂层或在接触时杀死微生物的层。 非浸出抗微生物涂层或层是固定在基底表面上的具有不可浸出与基质相关的杀生物金属材料的有机基质的独特组合。 当微生物接触涂层或层时，杀生物金属材料以足以使其杀死的量转移到微生物中。
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