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1.REGENERATION AND REPAIR OF NEURAL TISSUE USING POSTPARTUM-DERIVED CELLS 有权
标题翻译: 使用POSTPART-DERIVED细胞再生和修复神经组织公开(公告)号:US20100260843A1
公开(公告)日:2010-10-14
申请号:US12429849
申请日:2009-04-24
申请人: Darin J. Messina , Sanjay Mistry , Alexander M. Harmon , Ian Ross Harris , Anthony J. Kihm , Agnieszka Seyda , Chin-Feng Yi , Anna Gosiewska
发明人: Darin J. Messina , Sanjay Mistry , Alexander M. Harmon , Ian Ross Harris , Anthony J. Kihm , Agnieszka Seyda , Chin-Feng Yi , Anna Gosiewska
CPC分类号: A61K35/51 , A01N1/0226 , A61K35/12 , A61K35/50 , A61K38/18 , A61K38/1808 , A61K38/1825 , A61K38/1833 , A61K38/1841 , A61K38/185 , A61K38/1858 , A61K38/1866 , A61K38/1891 , A61K38/19 , A61K38/204 , A61K38/2053 , A61K38/27 , A61K45/06 , C12N5/0605 , C12N5/0606 , C12N5/0607 , C12N2500/32 , C12N2500/34 , C12N2500/44 , C12N2500/90 , C12N2500/95 , C12N2501/12 , C12N2501/21 , C12N2501/23 , C12N2502/02 , C12N2506/02 , C12N2506/03 , C12N2509/00 , C12N2509/10 , C12N2533/50
摘要: Cells derived from postpartum umbilicus and placenta are disclosed. Pharmaceutical compositions, devices and methods for the regeneration or repair of neural tissue using the postpartum-derived cells are also disclosed.
摘要翻译: 公开了产自产后脐带和胎盘的细胞。 还公开了使用产后来源细胞进行神经组织再生或修复的药物组合物,装置和方法。
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2.Postpartum cells derived from placental tissue, and methods of making and using the same 有权
标题翻译: 来自胎盘组织的产后细胞,以及制造和使用胎盘组织的方法公开(公告)号:US09579351B2
公开(公告)日:2017-02-28
申请号:US10877446
申请日:2004-06-25
申请人: Anthony J. Kihm , Ian Ross Harris , Sanjay Mistry , Alexander M. Harmon , Darin J. Messina , Agnieszka Seyda , Chin-Feng Yi , Anna Gosiewska
发明人: Anthony J. Kihm , Ian Ross Harris , Sanjay Mistry , Alexander M. Harmon , Darin J. Messina , Agnieszka Seyda , Chin-Feng Yi , Anna Gosiewska
CPC分类号: A61K35/51 , A01N1/0226 , A61K35/12 , A61K35/50 , A61K38/18 , A61K38/1808 , A61K38/1825 , A61K38/1833 , A61K38/1841 , A61K38/185 , A61K38/1858 , A61K38/1866 , A61K38/1891 , A61K38/19 , A61K38/204 , A61K38/2053 , A61K38/27 , A61K45/06 , C12N5/0605 , C12N5/0606 , C12N5/0607 , C12N2500/32 , C12N2500/34 , C12N2500/44 , C12N2500/90 , C12N2500/95 , C12N2501/12 , C12N2501/21 , C12N2501/23 , C12N2502/02 , C12N2506/02 , C12N2506/03 , C12N2509/00 , C12N2509/10 , C12N2533/50
摘要: Cells derived from postpartum placenta and methods for their isolation are provided by the invention. The invention further provides cultures and compositions of the placenta-derived cells. The placenta-derived cells of the invention have a plethora of uses, including but not limited to research, diagnostic, and therapeutic applications.
摘要翻译: 由产后胎盘衍生的细胞及其分离方法由本发明提供。 本发明还提供了胎盘衍生细胞的培养物和组合物。 本发明的胎盘衍生细胞具有许多用途,包括但不限于研究,诊断和治疗应用。
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公开(公告)号:US11191789B2
公开(公告)日:2021-12-07
申请号:US10876998
申请日:2004-06-25
申请人: Anthony J. Kihm , Agnieszka Seyda , Sridevi Dhanaraj , Ziwei Wang , Alexander M. Harmon , Ian Ross Harris , Darin J. Messina , Sanjay Mistry , Anna Gosiewska , Chin-Feng Yi
发明人: Anthony J. Kihm , Agnieszka Seyda , Sridevi Dhanaraj , Ziwei Wang , Alexander M. Harmon , Ian Ross Harris , Darin J. Messina , Sanjay Mistry , Anna Gosiewska , Chin-Feng Yi
IPC分类号: A61K48/00 , A61K35/51 , C12N5/074 , C12N5/073 , A61K38/18 , A61K38/19 , A61K38/20 , A61K38/27 , C12N5/0735 , A61K35/50 , A61K35/12
摘要: Cells derived from postpartum tissue and methods for their isolation and induction to differentiate to cells of a chondrogenic or osteogenic phenotype are provided by the invention. The invention further provides cultures and compositions of the postpartum-derived cells and products related thereto. The postpartum-derived cells of the invention and products related thereto have a plethora of uses, including but not limited to research, diagnostic, and therapeutic applications, for example, in the treatment of bone and cartilage conditions.
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4.REGENERATION AND REPAIR OF NEURAL TISSUE USING POSTPARTUM-DERIVED CELLS 有权
标题翻译: 使用POSTPART-DERIVED细胞再生和修复神经组织公开(公告)号:US20130022585A1
公开(公告)日:2013-01-24
申请号:US13605716
申请日:2012-09-06
申请人: DARIN J. MESSINA , Sanjay Mistry , Alexander M. Harmon , Ian Ross Harris , Anthony J. Kihm , Agnieszka Seyda , Chin-Feng Yi , Anna Gosiewska
发明人: DARIN J. MESSINA , Sanjay Mistry , Alexander M. Harmon , Ian Ross Harris , Anthony J. Kihm , Agnieszka Seyda , Chin-Feng Yi , Anna Gosiewska
CPC分类号: A61K35/51 , A01N1/0226 , A61K35/12 , A61K35/50 , A61K38/18 , A61K38/1808 , A61K38/1825 , A61K38/1833 , A61K38/1841 , A61K38/185 , A61K38/1858 , A61K38/1866 , A61K38/1891 , A61K38/19 , A61K38/204 , A61K38/2053 , A61K38/27 , A61K45/06 , C12N5/0605 , C12N5/0606 , C12N5/0607 , C12N2500/32 , C12N2500/34 , C12N2500/44 , C12N2500/90 , C12N2500/95 , C12N2501/12 , C12N2501/21 , C12N2501/23 , C12N2502/02 , C12N2506/02 , C12N2506/03 , C12N2509/00 , C12N2509/10 , C12N2533/50
摘要: Cells derived from postpartum umbilicus and placenta are disclosed. Pharmaceutical compositions, devices and methods for the regeneration or repair of neural tissue using the postpartum-derived cells are also disclosed.
摘要翻译: 公开了产自产后脐带和胎盘的细胞。 还公开了使用产后来源细胞进行神经组织再生或修复的药物组合物,装置和方法。
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5.
公开(公告)号:US08277796B2
公开(公告)日:2012-10-02
申请号:US12429849
申请日:2009-04-24
申请人: Darin J. Messina , Sanjay Mistry , Alexander M. Harmon , Ian Ross Harris , Anthony J. Kihm , Agnieszka Seyda , Chin-Feng Yi , Anna Gosiewska
发明人: Darin J. Messina , Sanjay Mistry , Alexander M. Harmon , Ian Ross Harris , Anthony J. Kihm , Agnieszka Seyda , Chin-Feng Yi , Anna Gosiewska
CPC分类号: A61K35/51 , A01N1/0226 , A61K35/12 , A61K35/50 , A61K38/18 , A61K38/1808 , A61K38/1825 , A61K38/1833 , A61K38/1841 , A61K38/185 , A61K38/1858 , A61K38/1866 , A61K38/1891 , A61K38/19 , A61K38/204 , A61K38/2053 , A61K38/27 , A61K45/06 , C12N5/0605 , C12N5/0606 , C12N5/0607 , C12N2500/32 , C12N2500/34 , C12N2500/44 , C12N2500/90 , C12N2500/95 , C12N2501/12 , C12N2501/21 , C12N2501/23 , C12N2502/02 , C12N2506/02 , C12N2506/03 , C12N2509/00 , C12N2509/10 , C12N2533/50
摘要: Cells derived from postpartum umbilicus and placenta are disclosed. Pharmaceutical compositions, devices and methods for the regeneration or repair of neural tissue using the postpartum-derived cells are also disclosed.
摘要翻译: 公开了产自产后脐带和胎盘的细胞。 还公开了使用产后来源细胞进行神经组织再生或修复的药物组合物,装置和方法。
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6.POSTPARTUM CELLS DERIVED FROM UMBILICAL CORD TISSUE, AND METHODS OF MAKING AND USING THE SAME 有权
标题翻译: 从脐带组织衍生的POSTPARTUM细胞及其制备方法和使用方法公开(公告)号:US20100210013A1
公开(公告)日:2010-08-19
申请号:US12389305
申请日:2009-02-19
申请人: Sanjay Mistry , Anthony J. Kihm , Ian Ross Harris , Alexander M. Harmon , Darin J. Messina , Agnieszka Seyda , Chin-Feng Yi , Anna Gosiewska
发明人: Sanjay Mistry , Anthony J. Kihm , Ian Ross Harris , Alexander M. Harmon , Darin J. Messina , Agnieszka Seyda , Chin-Feng Yi , Anna Gosiewska
IPC分类号: C12N5/071
CPC分类号: A61K35/51 , A01N1/0226 , A61K35/12 , A61K35/50 , A61K38/18 , A61K38/1808 , A61K38/1825 , A61K38/1833 , A61K38/1841 , A61K38/185 , A61K38/1858 , A61K38/1866 , A61K38/1891 , A61K38/19 , A61K38/204 , A61K38/2053 , A61K38/27 , A61K45/06 , C12N5/0605 , C12N5/0606 , C12N5/0607 , C12N2500/32 , C12N2500/34 , C12N2500/44 , C12N2500/90 , C12N2500/95 , C12N2501/12 , C12N2501/21 , C12N2501/23 , C12N2502/02 , C12N2506/02 , C12N2506/03 , C12N2509/00 , C12N2509/10 , C12N2533/50
摘要: Cells derived from human umbilical cords are disclosed along with methods for their therapeutic use. Isolation techniques, culture methods and detailed characterization of the cells with respect to their cell surface markers, gene expression, and their secretion of trophic factors are described.
摘要翻译: 公开了源自人脐带的细胞及其治疗用途的方法。 描述了相对于其细胞表面标志物的细胞的分离技术,培养方法和详细表征,基因表达及其营养因子的分泌。
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7.
公开(公告)号:US07560276B2
公开(公告)日:2009-07-14
申请号:US10877009
申请日:2004-06-25
申请人: Alexander M. Harmon , Ian Ross Harris , Anthony J. Kihm , Sanjay Mistry , Darin J. Messina , Agnieszka Seyda , Chin-Feng Yi , Anna Gosiewska
发明人: Alexander M. Harmon , Ian Ross Harris , Anthony J. Kihm , Sanjay Mistry , Darin J. Messina , Agnieszka Seyda , Chin-Feng Yi , Anna Gosiewska
IPC分类号: C12N5/00
CPC分类号: A61K35/51 , A01N1/0226 , A61K35/12 , A61K35/50 , A61K38/18 , A61K38/1808 , A61K38/1825 , A61K38/1833 , A61K38/1841 , A61K38/185 , A61K38/1858 , A61K38/1866 , A61K38/1891 , A61K38/19 , A61K38/204 , A61K38/2053 , A61K38/27 , A61K45/06 , C12N5/0605 , C12N5/0606 , C12N5/0607 , C12N2500/32 , C12N2500/34 , C12N2500/44 , C12N2500/90 , C12N2500/95 , C12N2501/12 , C12N2501/21 , C12N2501/23 , C12N2502/02 , C12N2506/02 , C12N2506/03 , C12N2509/00 , C12N2509/10 , C12N2533/50
摘要: Cells derived from postpartum tissue having the potential to support cells of and/or differentiate to cells of a soft tissue lineage, and methods of preparation and use of those postpartum tissue-derived cells, are provided by the invention. The invention also provides methods for the use of such postpartum-derived cells and products related thereto in therapies for conditions of soft tissue.
摘要翻译: 本发明提供了具有支持细胞和/或分化为软组织谱系细胞的潜力的产后组织的细胞,以及这些产后组织来源的细胞的制备和使用方法。 本发明还提供了在用于软组织病症的疗法中使用这种产后衍生细胞和与之相关的产品的方法。
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8.
公开(公告)号:US09498501B2
公开(公告)日:2016-11-22
申请号:US12389305
申请日:2009-02-19
申请人: Sanjay Mistry , Anthony J. Kihm , Ian R. Harris , Alexander M. Harmon , Darin J. Messina , Agnieszka Seyda , Chin-Feng Yi , Anna Gosiewska
发明人: Sanjay Mistry , Anthony J. Kihm , Ian R. Harris , Alexander M. Harmon , Darin J. Messina , Agnieszka Seyda , Chin-Feng Yi , Anna Gosiewska
CPC分类号: A61K35/51 , A01N1/0226 , A61K35/12 , A61K35/50 , A61K38/18 , A61K38/1808 , A61K38/1825 , A61K38/1833 , A61K38/1841 , A61K38/185 , A61K38/1858 , A61K38/1866 , A61K38/1891 , A61K38/19 , A61K38/204 , A61K38/2053 , A61K38/27 , A61K45/06 , C12N5/0605 , C12N5/0606 , C12N5/0607 , C12N2500/32 , C12N2500/34 , C12N2500/44 , C12N2500/90 , C12N2500/95 , C12N2501/12 , C12N2501/21 , C12N2501/23 , C12N2502/02 , C12N2506/02 , C12N2506/03 , C12N2509/00 , C12N2509/10 , C12N2533/50
摘要: Cells derived from human umbilical cords are disclosed along with methods for their therapeutic use. Isolation techniques, culture methods and detailed characterization of the cells with respect to their cell surface markers, gene expression, and their secretion of trophic factors are described.
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9.
公开(公告)号:US07524489B2
公开(公告)日:2009-04-28
申请号:US10877269
申请日:2004-06-25
申请人: Darin J. Messina , Sanjay Mistry , Alexander M. Harmon , Ian Ross Harris , Anthony J. Kihm , Agnieszka Seyda , Chin-Feng Yi
发明人: Darin J. Messina , Sanjay Mistry , Alexander M. Harmon , Ian Ross Harris , Anthony J. Kihm , Agnieszka Seyda , Chin-Feng Yi
CPC分类号: A61K35/51 , A01N1/0226 , A61K35/12 , A61K35/50 , A61K38/18 , A61K38/1808 , A61K38/1825 , A61K38/1833 , A61K38/1841 , A61K38/185 , A61K38/1858 , A61K38/1866 , A61K38/1891 , A61K38/19 , A61K38/204 , A61K38/2053 , A61K38/27 , A61K45/06 , C12N5/0605 , C12N5/0606 , C12N5/0607 , C12N2500/32 , C12N2500/34 , C12N2500/44 , C12N2500/90 , C12N2500/95 , C12N2501/12 , C12N2501/21 , C12N2501/23 , C12N2502/02 , C12N2506/02 , C12N2506/03 , C12N2509/00 , C12N2509/10 , C12N2533/50
摘要: Cells derived from postpartum umbilicus and placenta are disclosed. Pharmaceutical compositions, devices and methods for the regeneration or repair of neural tissue using the postpartum-derived cells are also disclosed.
摘要翻译: 公开了产自产后脐带和胎盘的细胞。 还公开了使用产后来源细胞进行神经组织再生或修复的药物组合物,装置和方法。
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10.
公开(公告)号:US08658152B2
公开(公告)日:2014-02-25
申请号:US13605716
申请日:2012-09-06
申请人: Darin J. Messina , Alexander M. Harmon , Ian R. Harris , Anthony J. Kihm , Sanjay Mistry , Agnieszka Seyda , Chin-Feng Yi , Anna Gosiewska
发明人: Darin J. Messina , Alexander M. Harmon , Ian R. Harris , Anthony J. Kihm , Sanjay Mistry , Agnieszka Seyda , Chin-Feng Yi , Anna Gosiewska
CPC分类号: A61K35/51 , A01N1/0226 , A61K35/12 , A61K35/50 , A61K38/18 , A61K38/1808 , A61K38/1825 , A61K38/1833 , A61K38/1841 , A61K38/185 , A61K38/1858 , A61K38/1866 , A61K38/1891 , A61K38/19 , A61K38/204 , A61K38/2053 , A61K38/27 , A61K45/06 , C12N5/0605 , C12N5/0606 , C12N5/0607 , C12N2500/32 , C12N2500/34 , C12N2500/44 , C12N2500/90 , C12N2500/95 , C12N2501/12 , C12N2501/21 , C12N2501/23 , C12N2502/02 , C12N2506/02 , C12N2506/03 , C12N2509/00 , C12N2509/10 , C12N2533/50
摘要: Cells derived from postpartum umbilicus and placenta are disclosed. Pharmaceutical compositions, devices and methods for the regeneration or repair of neural tissue using the postpartum-derived cells are also disclosed.
摘要翻译: 公开了产自产后脐带和胎盘的细胞。 还公开了使用产后来源细胞进行神经组织再生或修复的药物组合物,装置和方法。
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