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公开(公告)号:US06168797A
公开(公告)日:2001-01-02
申请号:US09376689
申请日:1999-08-18
申请人: Sanjoy Biswas , Martin K R Burnham , Jason C Fedon , David J Holmes , Karen A Ingraham , Howard Kallender , John T Lonsdale , Marie J Mazzulla , Karen M O'Dwyer , Leslie M Palmer , Chi Young So , Christopher M Traini , Glenn S Van Aller , Stephanie Van Horn , Magdalena Zalacain
发明人: Sanjoy Biswas , Martin K R Burnham , Jason C Fedon , David J Holmes , Karen A Ingraham , Howard Kallender , John T Lonsdale , Marie J Mazzulla , Karen M O'Dwyer , Leslie M Palmer , Chi Young So , Christopher M Traini , Glenn S Van Aller , Stephanie Van Horn , Magdalena Zalacain
IPC分类号: A61K3909
CPC分类号: C12N9/1029
摘要: The invention provides fabF polypeptides and polynucleotides encoding fabF polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing fabF polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供了fabF多肽和编码fabF多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用fabF多肽筛选抗菌化合物的方法。
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公开(公告)号:US06511839B1
公开(公告)日:2003-01-28
申请号:US09591041
申请日:2000-06-09
申请人: Pan Fong Chan , Sanjoy Biswas , David J. Holmes , Michael A. Lonetto , Leslie M. Palmer , Stephanie Van Horn , Richard L. Warren, Jr. , Magdalena Zalacain
发明人: Pan Fong Chan , Sanjoy Biswas , David J. Holmes , Michael A. Lonetto , Leslie M. Palmer , Stephanie Van Horn , Richard L. Warren, Jr. , Magdalena Zalacain
IPC分类号: C12N1511
CPC分类号: C12N9/1205 , A61K38/00
摘要: The invention provides fucose kinase promoter polynucleotides and methods for producing and using such polynucleotides, as well as their variants, agonists and antagonists, and their uses.
摘要翻译: 本发明提供岩藻糖激酶启动子多核苷酸以及用于产生和使用这些多核苷酸的方法及其变体,激动剂和拮抗剂及其用途。
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公开(公告)号:US06316211B1
公开(公告)日:2001-11-13
申请号:US09491785
申请日:2000-01-26
IPC分类号: G01N33569
摘要: The invention provides thdF polynucleotides encoding thdF polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing thdF polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供编码thdF多肽的thdF多核苷酸和通过重组技术产生此类多肽的方法。 还提供了利用thdF多肽筛选抗菌化合物的方法。
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公开(公告)号:US06326172B1
公开(公告)日:2001-12-04
申请号:US09433994
申请日:1999-11-04
申请人: Sanjoy Biswas , Martin Karl Russel Burnham , Alison Francis Chalker , David John Holmes , Karen Anne Ingraham , Chi Young So , Patrick Vernon Warren , Stephanie Van Horn , Magdalena Zalacain
发明人: Sanjoy Biswas , Martin Karl Russel Burnham , Alison Francis Chalker , David John Holmes , Karen Anne Ingraham , Chi Young So , Patrick Vernon Warren , Stephanie Van Horn , Magdalena Zalacain
IPC分类号: C12N1509
CPC分类号: C07K14/3156 , A61K38/00 , A61K48/00 , C07K14/315
摘要: The invention provides ytgP polypeptides and polynucleotides encoding ytgP polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ytgP polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供ytgP多肽和编码ytgP多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用ytgP多肽筛选抗菌化合物的方法。
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公开(公告)号:US06245542B1
公开(公告)日:2001-06-12
申请号:US09306276
申请日:1999-05-06
申请人: Sanjoy Biswas , Alexander Bryant , James Raymond Brown , Alison Francis Chalker , David John Holmes , Karen Anne Ingraham , Chi Young So , Stephanie Van Horn , Richard Lloyd Warren , Magdalena Zalacain
发明人: Sanjoy Biswas , Alexander Bryant , James Raymond Brown , Alison Francis Chalker , David John Holmes , Karen Anne Ingraham , Chi Young So , Stephanie Van Horn , Richard Lloyd Warren , Magdalena Zalacain
IPC分类号: C12N910
CPC分类号: C12N9/1007 , A61K38/00
摘要: The invention provides yfjO polypeptides and polynucleotides encoding yfjO polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing yfjO polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供了yfjO多肽和编码yfjO多肽的多核苷酸,以及通过重组技术产生此类多肽的方法。 还提供了利用yfj多肽筛选抗菌化合物的方法。
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公开(公告)号:US06399343B1
公开(公告)日:2002-06-04
申请号:US09574912
申请日:2000-05-19
申请人: Sanjoy Biswas , James Raymond Brown , Martin Karl Russel Burnham , Alison Francis Chalker , Richard Lloyd Warren , Magdalena Zalacain , Chi Young So , Christopher M Traini , David John Holmes , Karen Anne Ingraham , Thomas B Mathie
发明人: Sanjoy Biswas , James Raymond Brown , Martin Karl Russel Burnham , Alison Francis Chalker , Richard Lloyd Warren , Magdalena Zalacain , Chi Young So , Christopher M Traini , David John Holmes , Karen Anne Ingraham , Thomas B Mathie
IPC分类号: C12N900
CPC分类号: C07K14/3156 , A61K38/00 , A61K39/00 , A61K48/00 , Y10S435/885
摘要: The invention provides infB polypeptides and polynucleotides encoding infB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing in polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供编码infB多肽的infB多肽和多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了在多肽中利用筛选抗菌化合物的方法。
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公开(公告)号:US6110685A
公开(公告)日:2000-08-29
申请号:US283763
申请日:1999-04-01
申请人: Sanjoy Biswas , James Raymond Brown , Martin Karl Russel Burnham , Alison Francis Chalker , Richard Lloyd Warren , Magdalena Zalacain , Chi Young So , Christopher M Traini , David John Holmes , Karen Anne Ingraham , Thomas B Mathie
发明人: Sanjoy Biswas , James Raymond Brown , Martin Karl Russel Burnham , Alison Francis Chalker , Richard Lloyd Warren , Magdalena Zalacain , Chi Young So , Christopher M Traini , David John Holmes , Karen Anne Ingraham , Thomas B Mathie
CPC分类号: C07K14/3156 , A61K38/00 , A61K39/00 , A61K48/00 , Y10S435/885
摘要: The invention provides infB polypeptides and polynucleotides encoding in polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing infB polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供了在多肽中编码的infB多肽和多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用infB多肽筛选抗菌化合物的方法。
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公开(公告)号:US06225457B1
公开(公告)日:2001-05-01
申请号:US09305001
申请日:1999-05-04
申请人: Sanjoy Biswas , James Raymond Brown , Martin K R Burnham , Alison Francis Chalker , David John Holmes , Karen Anne Ingraham , Thomas B Mathie , Richard Lloyd Warren , Magdalena Zalacain
发明人: Sanjoy Biswas , James Raymond Brown , Martin K R Burnham , Alison Francis Chalker , David John Holmes , Karen Anne Ingraham , Thomas B Mathie , Richard Lloyd Warren , Magdalena Zalacain
IPC分类号: C07H2104
CPC分类号: C07K14/3156 , A61K38/00 , A61K48/00 , C07K2319/00
摘要: The invention provides murF2 polypeptides and polynucleotides encoding murF2 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing murF2 polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供了编码murF2多肽的murF2多肽和多核苷酸以及通过重组技术产生这种多肽的方法。 还提供了利用murF2多肽筛选抗菌化合物的方法。
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公开(公告)号:US06274361B1
公开(公告)日:2001-08-14
申请号:US09080662
申请日:1998-05-18
申请人: Sanjoy Biswas , Martin K. R. Burnham , Andrew P. Fosberry , John E Hodgson , Elizabeth J Lawlor , Tong Li , Damien McDevitt , Christopher Michael Traini , Martin Rosenberg , Judith Ward , Richard Lloyd Warren , Magdalena Zalacain
发明人: Sanjoy Biswas , Martin K. R. Burnham , Andrew P. Fosberry , John E Hodgson , Elizabeth J Lawlor , Tong Li , Damien McDevitt , Christopher Michael Traini , Martin Rosenberg , Judith Ward , Richard Lloyd Warren , Magdalena Zalacain
IPC分类号: C12N916
CPC分类号: C12N9/18
摘要: The invention provides pth polypeptides and polynucleotides encoding pth polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pth polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供第p多肽和编码第p多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用第p多肽筛选抗菌化合物的方法。
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公开(公告)号:US06294652B1
公开(公告)日:2001-09-25
申请号:US09487370
申请日:2000-01-18
申请人: Sanjoy Biswas , James Yigong Ge , David John Holmes , Karen A Ingraham , John Throup , Nicola Gail Wallis , Magdalena Zalacain
发明人: Sanjoy Biswas , James Yigong Ge , David John Holmes , Karen A Ingraham , John Throup , Nicola Gail Wallis , Magdalena Zalacain
IPC分类号: C01K100
CPC分类号: C12N9/1223 , C07K14/3156 , Y10T436/105831
摘要: The invention provides Response regulator polypeptides and polynucleotides encoding Response regulator polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing Response regulator polypeptides to screen for antibacterial compounds.
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