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1.发明授权5-alkylidene-2-halo-4-substituted-2-cyclopentenone and process for production thereof 失效5-亚烷基-2-卤代-4-取代-2-环戊烯酮及其制备方法
公开(公告)号：US4689426A
公开(公告)日：1987-08-25
申请号：US628107
申请日：1984-07-05
申请人： Satoshi Sugiura , Toshio Tanaka , Seizi Kurozumi
发明人： Satoshi Sugiura , Toshio Tanaka , Seizi Kurozumi
IPC分类号： C07C405/00 , C07C177/00
CPC分类号： C07C405/00
摘要： Novel 5-alkylidene-2-halo-4-substituted-2-cyclopentenone and process for production thereof. The novel 5-alkylidene-2-halo-4-substituted-2-cyclopentenones are represented by the following formula (I): ##STR1## wherein R.sub.a represents a substituted or unsubstituted aliphatic hydrocarbon group having 1 to 12 carbon atoms or a substituted or unsubstituted phenyl group, R.sub.b represents a substituted or unsubstituted aliphatic hydrocarbon group having 1 to 12 carbon atoms, and X represents a halogen atom. The novel cyclopentenones possess excellent pharmaceutical activities including anti-tumor activity, antiviral activity and antimicrobial activity.
摘要翻译： 新型5-亚烷基-2-卤代-4-取代-2-环戊烯酮及其制备方法。 新型5-亚烷基-2-卤代-4-取代-2-环戊烯酮由下式（I）表示：其中R a表示取代或未取代的碳原子数为1至12的脂族烃基或 取代或未取代的苯基，Rb表示取代或未取代的碳原子数1〜12的脂肪族烃基，X表示卤素原子。 新型环戊烯酮具有优异的药物活性，包括抗肿瘤活性，抗病毒活性和抗菌活性。
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公开(公告)号：US5116869A
公开(公告)日：1992-05-26
申请号：US759785
申请日：1991-09-03
申请人： Satoshi Sugiura , Atsuo Hazato , Toru Minoshima , Yoshinori Kato , Yasuko Koshihara , Seizi Kurozumi
发明人： Satoshi Sugiura , Atsuo Hazato , Toru Minoshima , Yoshinori Kato , Yasuko Koshihara , Seizi Kurozumi
IPC分类号： C07C317/24 , C07C323/22 , C07C405/00 , C07D303/32 , C07D303/40
CPC分类号： C07C317/24 , C07C323/22 , C07C405/00 , C07C405/0033 , C07D303/32 , C07D303/40 , C07C2101/10
摘要： 2-Substituted-2-cyclopentenones represented by the formula (I): ##STR1## wherein A is a hydroxyl group or ##STR2## and B is a hydrogen atom or A and B are bonded together to form one bonding arm;R.sup.1 represents a substituted or unsubstituted hydrocarbon group having 1 to 10 carbon atoms;R.sup.2 represents a substituted or unsubstituted aliphatic hydrocarbon group having 1 to 10 carbon atoms;R.sup.3 represents a substituted or unsubstituted aliphatic hydrocarbon group having 1 to 10 carbon atoms; wherein,when R.sup.3 is a single bond bonded to the cyclopentene skeleton, X represents a hydrogen atom, a hydroxyl group or a protected hydroxyl group; andwhen R.sup.3 is a double bond bonded to the pentene skeleton, X represents a bonding arm constituting a part of said double bond; andm and n independently represent 0, 1 or 2.
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3.发明授权Novel 5-membered cyclic compounds, process for production thereof, and pharmaceutical use thereof 失效新的5元环状化合物，其制备方法及其药物用途
公开(公告)号：US4766147A
公开(公告)日：1988-08-23
申请号：US823146
申请日：1986-01-29
IPC分类号： C07C59/90 , C07C405/00 , C07F7/18 , C07C177/00 , A61K31/557
CPC分类号： C07C405/00 , C07C405/0025 , C07C59/90 , C07F7/1856
摘要： Novel 5-alkylidene-4-substituted-2-cyclopentenones and 5-(1-hydroxy-aliphatic hydrocarbon)-4-substituted-2-cyclopentenones.These novel cyclopentenones and 5-alkylidene-3-hydroxy-4-substituted cyclopentanones have a pharmaceutical activity for treatment of tumors.
摘要翻译： 新的5-亚烷基-4-取代-2-环戊烯酮和5-（1-羟基 - 脂族烃）-4-取代-2-环戊烯酮。 这些新的环戊烯酮和5-亚烷基-3-羟基-4-取代的环戊酮具有治疗肿瘤的药物活性。
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4.发明授权Diagnostic imaging apparatus, magnetic resonance imaging apparatus, and X-ray CT apparatus 有权诊断成像装置，磁共振成像装置和X射线CT装置公开(公告)号：US08909321B2
公开(公告)日：2014-12-09
申请号：US12277441
申请日：2008-11-25
申请人： Satoshi Sugiura
发明人： Satoshi Sugiura
IPC分类号： A61B5/05 , G01V3/00 , G01R33/567 , G01R33/563 , G01R33/54 , A61B5/055 , A61B6/00 , A61B5/024
CPC分类号： A61B5/055 , A61B5/0037 , A61B5/024 , A61B6/503 , A61B6/504 , G01R33/543 , G01R33/546 , G01R33/56325 , G01R33/5635 , G01R33/56366 , G01R33/5676
摘要： A diagnostic imaging apparatus includes a ventricular volume-variation measuring unit that measures sequential variations in a size of a ventricle within at least one heart beat, from images of a heart scanned in each of a plurality of time phases; a scanning-condition setting unit that specifies a time phase of little cardiac motion based on variations in the size of the ventricle measured by the ventricular volume-variation measuring unit, and sets scanning conditions so as to collect data in the specified time phase; and an imaging unit that collects data based on the scanning conditions set by the scanning-condition setting unit, and reconstructs an image from the collected data.
摘要翻译： 诊断成像装置包括心室体积变化测量单元，其测量在多个时间段中的每一个中扫描的心脏的图像中的至少一个心跳内的心室的尺寸的顺序变化; 扫描条件设置单元，其基于由心室体积变化测量单元测量的脑室尺寸的变化来指定小心脏运动的时间相位，并且设置扫描条件以便以指定的时间段收集数据; 以及成像单元，其基于由扫描条件设置单元设置的扫描条件来收集数据，并且从所收集的数据重建图像。
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5.发明授权Near-field light device, recording apparatus using the same, and recording method 有权近场光装置，使用其的记录装置和记录方法公开(公告)号：US08830801B2
公开(公告)日：2014-09-09
申请号：US13984442
申请日：2012-02-17
IPC分类号： G11B11/00
CPC分类号： G11B13/08 , F21K9/60 , G11B5/02 , G11B5/4886 , G11B9/1409 , G11B2005/0021
摘要： A recording apparatus records information onto a recording medium. The recording apparatus is provided with: a near-field light device; and a control unit for controlling the near-field light device. The near-field light device is provided with: a light source; a quantum dot structure which is laminated on the light source; a plurality of quantity dots which are included in the quantity dot structure and each of which generates near-field light on the basis of light emitted from the light source; and an output end which is configured to output at least one portion of energy of the near-field light to the exterior of the quantity dot structure. The control unit of the recording apparatus controls the light source to emit the light upon recording the information, thereby increasing temperature of a region of the recording medium based on a size of the output end.
摘要翻译： 记录装置将信息记录到记录介质上。 记录装置设有：近场光装置; 以及用于控制近场光装置的控制单元。 近场灯装置设有：光源; 层叠在光源上的量子点结构; 多个量点包括在数量点结构中，并且每个点基于从光源发出的光产生近场光; 以及输出端，其被配置为将近场光的至少一部分能量输出到数量点结构的外部。 记录装置的控制单元在记录信息时控制光源发光，从而基于输出端的尺寸增加记录介质的区域的温度。
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公开(公告)号：US08560049B2
公开(公告)日：2013-10-15
申请号：US13283948
申请日：2011-10-28
IPC分类号： A61B5/05
CPC分类号： A61B5/055 , A61B5/0456 , A61B5/7207 , A61B5/7257 , A61B5/7285 , G01R33/4828 , G01R33/5605 , G01R33/5607 , G01R33/5615 , G01R33/5617 , G01R33/5635 , G01R33/5673
摘要： A magnetic resonance imaging (MRI) system obtains an MR image of an object. The system detects an ECG signal and performs a pulse sequence of RF gradient magnetic fields toward the object. Imaging defined by the pulse sequence is longer in temporal length than one heartbeat. The system further acquires an MR signal from the object in response to performance of the pulse sequence and produces the MR image based on the acquired MR signal. Also possible are: a plurality of divided MT pulses instead of the conventional single MT pulse, an SE-system pulse sequence having a shorter echo train spacing, and the generation of sounds by applying gradient pulses incorporated in an imaging pulse sequence so as to automatically instruct a patient to perform an intermittent breath hold.
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7.发明授权公开(公告)号：US08125222B2
公开(公告)日：2012-02-28
申请号：US12521806
申请日：2009-03-03
申请人： Satoshi Sugiura
发明人： Satoshi Sugiura
IPC分类号： G01V3/00
CPC分类号： G01R33/54 , G01R33/546
摘要： A storage unit stores a parameter list that defines a method of creating scanning conditions for a preparation scan from scanning conditions set for a main scan, with respect to each type of scanning. A scanning-condition edit/scan positioning unit receives an operation of selecting a type of a preparation scan, and when the operation of selecting the type of the preparation scan is received, the scanning-parameter limit calculating unit acquires the parameter list corresponding to the type of the preparation scan, from among the parameter lists stored by the storage unit, creates scanning conditions for the preparation scan from scanning conditions set for a main scan based on the parameter list corresponding to the type of the preparation scan. The pulse-sequence execution-data creating unit then causes execution of the preparation scan based on the created scanning conditions.
摘要翻译： 存储单元存储参数列表，该参数列表针对每种扫描类型定义从为主扫描设置的扫描条件创建用于准备扫描的扫描条件的方法。 扫描条件编辑/扫描定位单元接收选择准备扫描的类型的操作，并且当接收到选择准备扫描的类型的操作时，扫描参数限制计算单元获取与 基于与准备扫描的类型对应的参数列表，从存储单元存储的参数列表中的准备扫描的类型从为主扫描设置的扫描条件创建用于准备扫描的扫描条件。 脉冲序列执行数据创建单元然后基于所创建的扫描条件执行准备扫描。
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8.发明授权Apparatus and method for magnetic resonance angiography utilizing flow pulses and phase-encoding pulses in a same direction 有权利用流动脉冲和相位编码脉冲在相同方向进行磁共振血管造影的装置和方法公开(公告)号：US07647086B2
公开(公告)日：2010-01-12
申请号：US10678309
申请日：2003-10-06
申请人： Mitsue Miyazaki , Satoshi Sugiura
发明人： Mitsue Miyazaki , Satoshi Sugiura
IPC分类号： A61B5/05
CPC分类号： G01R33/56308 , G01R33/56316
摘要： A magnetic resonance imaging apparatus includes an RF coil unit which generates RF pulses toward a subject, and which receives an MR signal from the subject. Gradient magnetic field coils generate a gradient magnetic field for slice selection, a gradient magnetic field for phase encoding and a gradient magnetic field for frequency encoding, respectively. An arithmetic unit generates image data on the basis of the MR signal, and a sequence controller controls phase encoding gradient magnetic field coils in order to generate flow pulses for dephasing or rephasing the MR spin of blood flow within the subject, in the same direction as that of the phase encoding gradient magnetic field.
摘要翻译： 磁共振成像装置包括：向被检体产生RF脉冲的RF线圈单元，并从受检者接收MR信号。 梯度磁场线圈分别产生用于切片选择的梯度磁场，用于相位编码的梯度磁场和用于频率编码的梯度磁场。 算术单元根据MR信号生成图像数据，并且序列控制器控制相位编码梯度磁场线圈，以便产生用于使对象内的血流的MR自旋的相位相移或重新定位的流动脉冲，与 相位编码梯度磁场。
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9.发明授权公开(公告)号：US07587232B2
公开(公告)日：2009-09-08
申请号：US11362724
申请日：2006-02-28
申请人： Satoshi Sugiura
发明人： Satoshi Sugiura
CPC分类号： A61B5/055
摘要： Image reconstruction is executed by using magnetic resonance signals obtained by asynchronous multi-slice dynamic imaging without using any ECG-gated technique to obtain a plurality of MR images for each time phase with respect to a plurality of cross-sections corresponding to sequential changes in radio-frequency pulse frequency. The heart of a subject to be examined in MR images in the same time phase is developed by being divided into a plurality of small regions, and a developed view representing the average value of pixel values in each of the small regions is generated. For example, the developed views in the respective time phases are continuously displayed in a time-series manner.
摘要翻译： 通过使用通过异步多层动态成像获得的磁共振信号来执行图像重建，而不使用任何ECG门控技术来获得针对对应于无线电中的顺序变化的多个横截面的每个时间相位的多个MR图像 频率脉冲频率。 通过划分为多个小区域来开发在相同时间相位的MR图像中要检查的对象的心脏，并且生成表示每个小区域中的像素值的平均值的显影视图。 例如，以时间序列方式连续地显示各时间段的展开视图。
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公开(公告)号：USD599218S1
公开(公告)日：2009-09-01
申请号：US29335586
申请日：2009-04-17
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