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32 条记录 (耗时 0.039 秒)

    Method for predicting a golfer's ball striking performance
    1.
    发明申请
    Method for predicting a golfer's ball striking performance 有权

    公开(公告)号：US20050070366A1

    公开(公告)日：2005-03-31

    申请号：US10990147

    申请日：2004-11-15

    申请人： Scott Manwaring ,  Frank Fan ,  Peter Ligotti

    发明人： Scott Manwaring ,  Frank Fan ,  Peter Ligotti

    IPC分类号： A63B57/00 ,  A63B69/36

    CPC分类号： A63B69/36 ,  A63B57/00 ,  A63B2069/3605

    摘要： A system for a predicting golfer's performance is disclosed herein. The system inputs the pre-impact swing properties of a golfer, a plurality of mass properties of a first golf club, and a plurality of mass properties of a first golf ball into a rigid body code. Ball launch parameters are generated from the rigid body. The ball launch parameters, a plurality of atmospheric conditions and lift and drag properties of the golf ball are inputted into a trajectory code. This trajectory code is used to predict the performance of a golf ball if struck by the golfer with the golf club under the atmospheric conditions. The system can then predict the performance of the golf ball if struck by the golfer with a different golf club. The system of the present invention predicts the performance of the golf ball without the golfer actually striking the golf ball.

    Mutant protease biosensors with enhanced detection characteristics
    6.
    发明授权
    Mutant protease biosensors with enhanced detection characteristics 有权
    具有增强检测特性的突变蛋白酶生物传感器

    公开(公告)号：US08735559B2

    公开(公告)日：2014-05-27

    申请号：US13105648

    申请日：2011-05-11

    申请人： Brock Binkowski ,  Braeden Butler ,  Lance P. Encell ,  Frank Fan ,  Brad Hook ,  Paul Otto ,  Gediminas Vidugiris ,  Susan Wigdal ,  Kristopher Zimmerman

    发明人： Brock Binkowski ,  Braeden Butler ,  Lance P. Encell ,  Frank Fan ,  Brad Hook ,  Paul Otto ,  Gediminas Vidugiris ,  Susan Wigdal ,  Kristopher Zimmerman

    IPC分类号： C12N15/62 ,  C12N15/63 ,  C12N15/54 ,  C12N15/74 ,  C12N15/79

    CPC分类号： A61K49/0045 ,  A01K67/0275 ,  A61K49/0013 ,  C12N9/0069 ,  C12Q1/37 ,  C12Q1/66 ,  C12Y113/12007

    摘要： A polynucleotide encoding a biosensor polypeptide comprising a modified circularly-permuted thermostable luciferase and a linker linking the C-terminal portion of the thermostable luciferase to the N-terminal portion of the thermostable luciferase. The modified circularly-permuted thermostable luciferase is modified relative to a parental circularly-permuted thermostable luciferase. The linker contains a sensor region capable of interacting with a target molecule in a cell. The modified circularly-permuted thermostable luciferase has an enhanced response after interaction of the biosensor with the target molecule relative to the parental circularly-permuted thermostable luciferase in the presence of the target molecule. Alternatively, the modified circularly-permuted thermostable luciferase has an enhanced response after interaction of the biosensor with the target molecule relative to the modified circularly-permuted thermostable luciferase in the absence of the target molecule.

    摘要翻译： 编码包含修饰的环状置换的热稳定性荧光素酶的生物传感器多肽的多核苷酸和将热稳定性荧光素酶的C末端部分连接到热稳定性萤光素酶的N末端部分的接头。 相对于亲本循环置换的热稳定性荧光素酶，修饰的环状置换的热稳定性荧光素酶被修饰。 接头包含能够与细胞中的靶分子相互作用的传感器区域。 经修饰的环状置换的热稳定荧光素酶在目标分子存在下相对于亲本循环置换的热稳定性荧光素酶在生物传感器与靶分子相互作用后具有增强的响应。 或者，修饰的环状置换的热稳定荧光素酶在生物传感器与目标分子相互作用后相对于在不存在目标分子的情况下相对于经修饰的环状置换的热稳定性荧光素酶具有增强的响应。

    Hydrogel-driven micropump
    8.
    发明授权
    Hydrogel-driven micropump 失效
    水凝胶驱动的微型泵

    公开(公告)号：US07648619B2

    公开(公告)日：2010-01-19

    申请号：US11262266

    申请日：2005-10-28

    申请人： Sway Chuang ,  Morris Liang ,  Frank Fan ,  Wae-Honge Chen

    发明人： Sway Chuang ,  Morris Liang ,  Frank Fan ,  Wae-Honge Chen

    IPC分类号： B67D5/00

    CPC分类号： F04B43/043 ,  F04B19/006 ,  F04B19/24

    摘要： A hydrogel-driven micropump, comprising: two fluid chambers; a fluid channel, connecting the two fluid chambers; a first substrate plate and a second substrate plate, which are glass wafers produced by micromechanical working, each having accommodation chambers which are filled in hydrogel which are placed next to the two fluid chambers and connected by inward extending bridges, with electric terminals leading to the accommodation chambers; a middle substrate, sandwiched between the first and second substrate plates and made by a bulk micromachining process, having separated accommodation chambers close to ends thereof. A separating block is placed between the accommodation chambers. The middle substrate between the first and second substrate plates forms a micropump body. All of the substrates are separated by membranes. The accommodation chambers for electrophoretic fluid are located between the membranes and the first and second substrate plates, respectively, and insulating material. An electrophoretic fluid channel is left between the membranes and the bridges. The fluid channel is placed within the middle substrate between the membranes. The first substrate plate has through holes from outside to the two fluid chambers, allowing fluid to be injected.

    摘要翻译： 一种水凝胶驱动的微型泵，包括：两个流体室; 连接两个流体室的流体通道; 第一衬底板和第二衬底板，其是通过微机械加工制造的玻璃晶片，每个具有容纳室，其被填充在靠近两个流体室并且通过向内延伸的桥连接的水凝胶中，电端子通向 住宿室 中间基板夹在第一和第二基板之间并通过本体微加工工艺制成，其接近其端部具有分离的容纳室。 分离块放置在容纳室之间。 第一和第二基板之间的中间基板形成微型泵体。 所有的底物都被膜分离。 用于电泳液体的容纳室分别位于膜与第一和第二基板之间以及绝缘材料之间。 电泳流体通道留在膜和桥之间。 流体通道被放置在膜之间的中间基板内。 第一基板具有从外部到两个流体室的通孔，允许流体被注入。

    Gutter hanger
    9.
    发明授权
    Gutter hanger 有权
    沟槽衣架

    公开(公告)号：US07494095B2

    公开(公告)日：2009-02-24

    申请号：US11282755

    申请日：2005-11-21

    申请人： Simon Walker ,  Frank Fan ,  Karen Zhu

    发明人： Simon Walker ,  Frank Fan ,  Karen Zhu

    IPC分类号： E04D13/072

    CPC分类号： E04D13/0725

    摘要： A hanger for mounting a gutter to a structure with a fastener. The hanger may include a bracket arm having first and second ends and extend widthwise to the gutter. A raised fastener guide portion may be connected to the first end of the bracket for delivery of the fastener. An outside gutter engagement device connected to the second end of the bracket arm for engaging the outside wall of the gutter and an inside gutter engagement device connected to the fastener guide portion for engaging the inside wall of the gutter and for receiving the fastener to mount the gutter to the structure may also be provided. A support arm may also be provided having first and second ends. The first end may be connected to the raised fastener guide portion and the second end of the support arm may abut the inside wall of the gutter when the hanger is attached to the gutter.

    摘要翻译： 用于将沟槽安装到具有紧固件的结构的衣架。 衣架可以包括具有第一和第二端并且横向于沟槽延伸的支架臂。 升高的紧固件引导部分可以连接到支架的第一端，用于输送紧固件。 连接到支架臂的第二端的外部沟槽接合装置，用于接合沟槽的外壁，以及连接到紧固件引导部分的内部沟槽接合装置，用于接合沟槽的内壁并用于接收紧固件以安装 还可以提供对结构的沟槽。 还可以提供具有第一端和第二端的支撑臂。 第一端可以连接到升起的紧固件引导部分，并且当衣架附接到沟槽时，支撑臂的第二端可邻接沟槽的内壁。

    Integrating loosely coupled tools using contracts and references
    10.
    发明申请
    Integrating loosely coupled tools using contracts and references 有权
    使用合同和引用集成松散耦合的工具

    公开(公告)号：US20090007069A1

    公开(公告)日：2009-01-01

    申请号：US11823163

    申请日：2007-06-27

    申请人： Andrew Willis Bliven, II ,  Ian Bavey ,  Jack Greenfield ,  Frank Fan ,  David Trowbridge ,  David S. Noble ,  Michael Hayton ,  Vinay Bharadwaj

    发明人： Andrew Willis Bliven, II ,  Ian Bavey ,  Jack Greenfield ,  Frank Fan ,  David Trowbridge ,  David S. Noble ,  Michael Hayton ,  Vinay Bharadwaj

    IPC分类号： G06F9/44

    CPC分类号： G06F8/00 ,  G06F9/541

    摘要： Various technologies and techniques are disclosed for providing an integration framework that enables tools to be integrated. The integration framework enables tools participating in the framework to be encapsulated in a manner that hides their implementations, thereby preventing them from taking deep dependencies on each other. The integration framework also enables the tools participating in the framework to carry formal type definitions called service and data contracts that describe the public behaviors they offer. The integration framework also provides support for migrating integration logic from tools into pluggable commands to further reduce coupling between the tools.

    摘要翻译： 公开了各种技术和技术，用于提供集成框架，使得能够集成工具。 集成框架使参与框架的工具能够以隐藏其实现的方式进行封装，从而防止它们彼此之间的深度依赖。 集成框架还使参与框架的工具能够进行称为服务和数据合同的正式类型定义，以描述其提供的公共行为。 集成框架还支持将集成逻辑从工具迁移到可插拔命令，以进一步减少工具之间的耦合。