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    IMPLANTABLE VALVE DEVICE
    1.
    发明申请
    IMPLANTABLE VALVE DEVICE 审中-公开
    可植入阀装置

    公开(公告)号：US20090105813A1

    公开(公告)日：2009-04-23

    申请号：US12252918

    申请日：2008-10-16

    申请人： Sean Chambers ,  Ram Paul ,  Norman Jaffe

    发明人： Sean Chambers ,  Ram Paul ,  Norman Jaffe

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2475 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2220/0075 ,  A61F2240/001 ,  A61F2250/0098

    摘要： Valve devices, methods of making valve devices, and methods of treating various venous-related conditions, disorders and/or diseases are described. In one embodiment, a valve device includes an expandable support frame and a bioprosthetic valve attached to the support frame. The bioprosthetic valve comprises a leaflet and a contiguous wall portion harvested from a multi-leaflet xenogeneic valve. The contiguous wall portion includes the attachment region where the leaflets attaches to the vessel wall and, in some embodiments, includes the natural margins of attachment between the leaflet and vessel wall.

    摘要翻译： 描述了阀装置，制造阀装置的方法以及治疗各种静脉相关病症，病症和/或疾病的方法。 在一个实施例中，阀装置包括可扩展支撑框架和附接到支撑框架的生物假肢瓣膜。 生物假肢瓣膜包括从多叶瓣异种瓣膜收获的小叶和邻接的壁部分。 邻接的壁部分包括附件区域，其中小叶附着到血管壁，并且在一些实施例中包括叶片和血管壁之间的附着的天然边缘。

    Implantable valve device
    2.
    发明授权
    Implantable valve device 有权

    公开(公告)号：US10722365B2

    公开(公告)日：2020-07-28

    申请号：US15414794

    申请日：2017-01-25

    申请人： Sean Chambers ,  Ram Paul ,  Norman Jaffe

    发明人： Sean Chambers ,  Ram Paul ,  Norman Jaffe

    IPC分类号： A61F2/24

    摘要： Valve devices, methods of making valve devices, and methods of treating various venous-related conditions, disorders and/or diseases are described. In one embodiment, a valve device includes an expandable support frame and a bioprosthetic valve attached to the support frame. The bioprosthetic valve comprises a leaflet and a contiguous wall portion harvested from a multi-leaflet xenogeneic valve. The contiguous wall portion includes the attachment region where the leaflets attaches to the vessel wall and, in some embodiments, includes the natural margins of attachment between the leaflet and vessel wall.

    Implantable remodelable materials comprising magnetic material
    7.
    发明申请
    Implantable remodelable materials comprising magnetic material 审中-公开
    包括磁性材料的植入式可重塑材料

    公开(公告)号：US20070027460A1

    公开(公告)日：2007-02-01

    申请号：US11493065

    申请日：2006-07-26

    申请人： Brian Case ,  Ram Paul

    发明人： Brian Case ,  Ram Paul

    IPC分类号： A61F2/02

    CPC分类号： A61L27/02 ,  A61L27/3629 ,  A61L27/3633 ,  A61L27/3641 ,  A61L27/3645 ,  A61L27/50

    摘要： Devices, materials and methods for using the same for modifying or monitoring a valve within a body are provided herein. Devices comprising a magnetic material and magnetically-activated implantable devices are described. Methods of modifying a valve in the body, for a valve within a body vessel are also provided.

    摘要翻译： 本文提供了用于使用其来改变或监视主体内的阀的装置，材料和方法。 描述了包括磁性材料和磁激活可植入装置的装置。 还提供了改变身体中的阀，用于体内血管中的阀的方法。

    METHODS OF TREATING VENOUS VALVE RELATED CONDITIONS WITH A FLOW-MODIFYING IMPLANTABLE MEDICAL DEVICE
    8.
    发明申请
    METHODS OF TREATING VENOUS VALVE RELATED CONDITIONS WITH A FLOW-MODIFYING IMPLANTABLE MEDICAL DEVICE 审中-公开
    用流动修改植入式医疗装置处理通气阀相关条件的方法

    公开(公告)号：US20080051879A1

    公开(公告)日：2008-02-28

    申请号：US11844003

    申请日：2007-08-23

    申请人： Brian Case ,  Gary Shirley ,  Ram Paul ,  Jacob Flagle

    发明人： Brian Case ,  Gary Shirley ,  Ram Paul ,  Jacob Flagle

    IPC分类号： A61F2/06

    CPC分类号： A61F2/2475 ,  A61F2/07 ,  A61F2002/068

    摘要： Implantable medical devices adapted to modify fluid flow within a body vessel are provided herein. The medical devices may include a fluid flow restricting channel configured to reduce longitudinal fluid flow in a retrograde direction or in an antegrade direction. Preferably, the medical devices are flow-modifying devices that reduce fluid flow through the medical device to a greater extent in a retrograde direction than in an antegrade direction. Methods of treatment comprising the step of implanting a flow-modifying medical device within a body vessel are also provided. Flow-modifying devices are useful, for example, in treating venous valve related conditions.

    摘要翻译： 本文提供了适于改变体内容器内的流体流动的植入式医疗装置。 医疗装置可以包括流体流动限制通道，该流体流动限制通道构造成减小沿逆行方向或顺行方向的纵向流体流动。 优选地，医疗装置是流动改变装置，其减少流体通过医疗装置的流体在逆行方向上比在顺行方向上更大程度地流动。 还提供了包括在身体容器内植入流动改变医疗装置的步骤的治疗方法。 流动改变装置例如在治疗静脉瓣相关病症中是有用的。

    Artificial valve prosthesis
    9.
    发明申请
    Artificial valve prosthesis 有权
    人工瓣膜假体

    公开(公告)号：US20070288087A1

    公开(公告)日：2007-12-13

    申请号：US11807879

    申请日：2007-05-30

    申请人： Neal Fearnot ,  Alan Leewood ,  Ram Paul ,  Blayne Roeder ,  William Voorhees

    发明人： Neal Fearnot ,  Alan Leewood ,  Ram Paul ,  Blayne Roeder ,  William Voorhees

    IPC分类号： A61F2/06 ,  A61F2/24

    CPC分类号： A61F2/2418 ,  A61F2/2475 ,  A61F2220/005 ,  A61F2220/0058

    摘要： A self-expanding or otherwise expandable artificial valve prostheses for deployment within a body passageway, such as a vessel or duct of a patient. The valve prostheses include a support structure having an outer frame, a supporting member and a valve leaflet. The portion of the valve leaflet is supported by the supporting member and is positioned away from the wall of the body passageway when the device is deployed within the body passageway.

    摘要翻译： 用于展开在身体通道（例如患者的血管或导管）内的自膨胀或其他可膨胀的人造瓣膜假体。 瓣膜假体包括具有外框架，支撑构件和瓣膜小叶的支撑结构。 瓣膜小叶的部分由支撑构件支撑，并且当装置展开在身体通道内时，其被定位成远离身体通道的壁。

    MEDICAL DEVICE DELIVERY SYSTEMS THAT FACILITATE MEDICAL DEVICE PLACEMENT IN THE PRESENCE OF ULTRASONIC WAVES
    10.
    发明申请
    MEDICAL DEVICE DELIVERY SYSTEMS THAT FACILITATE MEDICAL DEVICE PLACEMENT IN THE PRESENCE OF ULTRASONIC WAVES 审中-公开
    在超声波存在下使医疗器械放置的医疗装置输送系统

    公开(公告)号：US20060259115A1

    公开(公告)日：2006-11-16

    申请号：US11382966

    申请日：2006-05-12

    申请人： Brian Case ,  Ram Paul

    发明人： Brian Case ,  Ram Paul

    IPC分类号： A61F2/06

    CPC分类号： A61F2/95 ,  A61F2/2436 ,  A61F2250/0015 ,  A61M37/0092

    摘要： Delivery systems, methods of fabricating delivery systems, and methods of implanting intraluminal medical devices at a point of treatment within a body vessel are provided. Delivery systems include an elongate tubular member that has first and second wall portions with different acoustic impedences. An intraluminal medical device is disposed on a mounting region of a dilator and within the elongate tubular member. One of the wall portions of the elongate tubular member is positioned substantially adjacent a functional mechanism of the intraluminal medical device. This positioning facilitates placement of the intraluminal medical device within a body vessel in a particular orientation by observing the differential reflection of ultrasonic waves caused by the different acoustic impedences of the first and second wall portions of the elongate tubular member. Rotatation of the delivery system following and/or during such an observation can be employed to achieve a desired orientation of the intraluminal medical device within the body vessel.

    摘要翻译： 提供输送系统，制造输送系统的方法以及在体内血管内的处理点植入管腔内医疗器械的方法。 递送系统包括具有不同声阻抗的第一和第二壁部分的细长管状构件。 管腔内医疗装置设置在扩张器的安装区域上并且在细长管状构件内。 细长管状构件的壁部分之一基本上邻近管腔内医疗装置的功能机构。 该定位有利于通过观察由细长管状构件的第一和第二壁部分的不同声阻抗引起的超声波的差异反射，便于将管腔内医疗装置以特定取向放置在体容器内。 在这种观察之后和/或在这样的观察期间，输送系统的旋转可用于实现体内血管内腔内医疗装置的期望定向。