摘要:
A process for preparing 7-[2-[4-(6-fluoro-3-methyl-1,2-benzisoxazol-5-yl)-1-piperazinyl]ethyl]-2-(1-propynyl)-7H-pyrazolo-[4,3-e]-[1,2,4]-triazolo[1,5-c]pyrimidin-5-amine, intermediates useful in that process, and processes for preparing said intermediates are disclosed.
摘要:
A process for preparing 7-[2-[4-(6-fluoro-3-methyl-1,2-benzisoxazol-5-yl)-1-piperazinyl]ethyl]-2-(1-propynyl)-7H-pyrazolo-[4,3-e]-[1,2,4]-triazolo[1,5-c]pyrimidin-5-amine, intermediates useful in that process, and processes for preparing said intermediates are disclosed.
摘要:
Processes useful for the preparation of a Compound of Formula I: Formula (I). Intermediates useful for the preparation of the compound of Formula I, and processes useful for preparing said intermediates are disclosed.
摘要:
Processes useful for the preparation of a Compound of Formula I: Formula (I). Intermediates useful for the preparation of the compound of Formula I, and processes useful for preparing said intermediates are disclosed.
摘要:
An electronic device detects erroneous key selection entries or inaccurate actuation of a keypad. The device has a keypad with aligned keys. Each of the keys is partitioned into two sensor sub regions. A first one of the sub-regions includes at least a first sensor and a second one of the sub-regions includes a second sensor. A processor with a keypad sensor inputs is selectively coupled to the first and second sensors of each of the sub-regions. The second sensor of the first key and a proximal first sensor of an adjacent second key are coupled to a common keypad sensor input to provide indistinguishable sub-regions of adjacent keys. The processor is programmed to detect an erroneous key selection entry when only a key actuation signal is provided from the common keypad sensor.
摘要:
A capacitive keypad position sensor includes a keypad touch panel having a first defined key area disposed in a plane having first and second orthogonal axes. First and second electrodes respectively occupy first and second areas below the first defined key area. Each electrode includes a plurality of parallel rows extending along the first axis and spaced apart from one another along the second axis. Each of the plurality of rows has a length along the first axis that is substantially equal to a width of the first defined key area along the first axis measured at a position along the second axis corresponding to the respective one of the plurality of rows. At least some of the first and second pluralities of rows are interleaved with one another.
摘要:
The present invention is directed to novel bicyclic heterocycles of structural formula (I) which are inhibitors of the dipeptidyl peptidase-IV enzyme and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
摘要:
The present invention relates to methods for the synthesis of chiral non-racemic products, e.g., enantiomerically-enriched hemiesters, from prochiral starting materials, e.g., meso anhydrides. The present invention also relates to catalysts for the aforementioned methods, and methods for synthesizing these catalysts.
摘要:
The present invention is directed to novel bicyclic heterocycles of structural formula (I) which are inhibitors of the dipeptidyl peptidase-IV enzyme and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
摘要:
Temperature accuracy is improved, conversion gain is increased without increasing current density and parasitic resistance errors and other problems with conventional bandgap reference temperature sensors are eliminated by generating a signal proportional to temperature from three samples, where the signal is defined as a difference between a first difference and a second difference, the first difference comprising a difference between a second sample and a first sample, the second difference comprising a difference between a third sample and the first sample, and where the signal is defined to cancel parasitic components in the first, second and third samples.