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    Clear liquid skin cosmetic compositions
    4.
    发明授权
    Clear liquid skin cosmetic compositions 失效
    透明液体皮肤化妆品组合物

    公开(公告)号：US4481187A

    公开(公告)日：1984-11-06

    申请号：US462720

    申请日：1983-02-01

    申请人： Mitsuo Kondo ,  Hiromi Minamino ,  Yasuhisa Otani ,  Akira Miyashita ,  Kenzo Okada ,  Takashi Kuramoto

    发明人： Mitsuo Kondo ,  Hiromi Minamino ,  Yasuhisa Otani ,  Akira Miyashita ,  Kenzo Okada ,  Takashi Kuramoto

    IPC分类号： A61K8/63 ,  A61Q19/00 ,  C07H15/24 ,  A61K7/021 ,  A61K7/15 ,  A61K7/46 ,  A61K7/48

    CPC分类号： A61Q19/00 ,  A61K8/63 ,  A61K2800/262 ,  A61Q1/02 ,  A61Q19/002 ,  A61Q19/10 ,  Y10S514/97

    摘要： Disclosed is a clear liquid skin cosmetic composition (e.g., a lotion) in which one or more oily substances (such as oil-soluble perfumes, hormones and the like) are solubilized in water with the aid of a solubilizing agent comprising an 18.alpha.-glycyrrhizin (18.alpha.-glycyrrhizic acid sodium salt, potassium salt or ammonium salt) that is a novel compound derived from a conventional glycyrrhizin (i.e., any form of 18.beta.-glycyrrhizin extracted from licorice root) or a glycyrrhizin composition consisting of an 18.alpha.-glycyrrhizin and an 18.beta.-glycyrrhizin. This skin cosmetic composition is not irritative to the skin as contrasted with skin cosmetic compositions prepared by using a synthetic surface-active agent as the solubilizing agent, and is not subject to gelation in a slightly acidic to acidic pH range as contrasted with skin cosmetic compositions prepared by using an 18.beta.-glycyrrhizin alone as the solubilizing agent. Moreover, this skin cosmetic composition exerts a mild action on the skin without causing irritation thereto, gives an agreeable feeling, and has excellent fluidity, usability and storage stability.

    摘要翻译： 公开了一种透明的液体皮肤化妆品组合物（例如洗剂），其中一种或多种油性物质（例如油溶性香料，激素等）借助于包含18α- 甘草甜素（18α-甘草酸钠盐，钾盐或铵盐），其是衍生自常规甘草酸的新化合物（即从甘草根提取的任何形式的18β-甘草甜素）或由18α- 甘草甜素和18β-甘草甜素。 与通过使用合成表面活性剂作为增溶剂制备的皮肤化妆品组合物相比，该皮肤化妆品组合物对皮肤不刺激，并且与皮肤化妆品组合物相比，在略微酸性至酸性pH范围内不经历凝胶化 通过使用单独的18β-甘草甜素作为增溶剂制备。 此外，该皮肤化妆品组合物对皮肤施加温和的作用而不会引起刺激，产生舒适的感觉，并且具有优异的流动性，可用性和储存稳定性。

    SURFACTANT, AND EMULSION COSMETIC AND LIPOSOME EACH CONTAINING THE SAME
    5.
    发明申请
    SURFACTANT, AND EMULSION COSMETIC AND LIPOSOME EACH CONTAINING THE SAME 审中-公开
    表面活性剂，和乳化剂化妆品和脂肪酸

    公开(公告)号：US20090098172A1

    公开(公告)日：2009-04-16

    申请号：US12325646

    申请日：2008-12-01

    申请人： Takeshi Ikemoto ,  Hiromi Minamino ,  Yasushi Sumida ,  Yoh-ichi Inoue

    发明人： Takeshi Ikemoto ,  Hiromi Minamino ,  Yasushi Sumida ,  Yoh-ichi Inoue

    IPC分类号： A61K8/06 ,  A61K8/60 ,  A61Q19/10 ,  A61Q19/00 ,  A61Q1/00

    CPC分类号： B01F17/0021 ,  A61K8/06 ,  A61K8/062 ,  A61K8/14 ,  A61K8/60 ,  A61K9/0014 ,  A61K9/1272 ,  A61K47/26 ,  A61Q5/02 ,  A61Q19/00 ,  A61Q19/10 ,  C07H13/02

    摘要： The invention provides a surfactant comprising at least one trehalose-6-fatty acid ester selected from those represented by the following formula: wherein R represents a saturated or unsaturated acyl group having 8-22 carbon atoms, and may have a hydroxyl group or other substituents, and an emulsion-type cosmetic composition comprising said surfactant and a water-soluble polymer. The surfactant of the invention has excellent surface activity and safety. Also, the emulsion-type cosmetic composition has excellent long-term storage stability and sensory properties, has no irritation to skin, and gives beautiful appearance with fine surface texture. Further, the invention is a liposome having a membrane wall composed of trehalose fatty acid ester. Said liposome has excellent chemical and physical stabilities such as long-term storage stability.

    摘要翻译： 本发明提供一种表面活性剂，其包含至少一种选自下式表示的海藻糖-6-脂肪酸酯：其中R表示具有8-22个碳原子的饱和或不饱和酰基，并且可具有羟基或其它取代基 和包含所述表面活性剂和水溶性聚合物的乳液型化妆品组合物。 本发明的表面活性剂具有优异的表面活性和安全性。 此外，乳液型化妆品组合物具有优异的长期保存稳定性和感官性能，对皮肤没有刺激性，并且具有精细的表面质地的美丽外观。 此外，本发明是具有由海藻糖脂肪酸酯构成的膜壁的脂质体。 所述脂质体具有优异的化学和物理稳定性，例如长期储存稳定性。

    Surfactant, and an emulsion-type cosmetic composition and a liposome containing said surfactant
    6.
    发明申请
    Surfactant, and an emulsion-type cosmetic composition and a liposome containing said surfactant 审中-公开
    表面活性剂和乳液型化妆品组合物和含有所述表面活性剂的脂质体

    公开(公告)号：US20070160556A1

    公开(公告)日：2007-07-12

    申请号：US11716870

    申请日：2007-03-12

    申请人： Takeshi Ikemoto ,  Hiromi Minamino ,  Yasushi Sumida ,  Yoh-ichi Inoue

    发明人： Takeshi Ikemoto ,  Hiromi Minamino ,  Yasushi Sumida ,  Yoh-ichi Inoue

    IPC分类号： A61K8/73 ,  C07H13/02

    CPC分类号： B01F17/0021 ,  A61K8/06 ,  A61K8/062 ,  A61K8/14 ,  A61K8/60 ,  A61K9/0014 ,  A61K9/1272 ,  A61K47/26 ,  A61Q5/02 ,  A61Q19/00 ,  A61Q19/10 ,  C07H13/02

    摘要： The invention provides a surfactant comprising at least one trehalose-6-fatty acid ester selected from those represented by the following formula: wherein R represents a saturated or unsaturated acyl group having 8-22 carbon atoms, and may have a hydroxyl group or other substituents, and an emulsion-type cosmetic composition comprising said surfactant and a water-soluble polymer. The surfactant of the invention has excellent surface activity and safety. Also, the emulsion-type cosmetic composition has excellent long-term storage stability and sensory properties, has no irritation to skin, and gives beautiful appearance with fine surface texture. Further, the invention is a liposome having a membrane wall composed of trehalose fatty acid ester. Said liposome has excellent chemical and physical stabilities such as long-term storage stability.

    摘要翻译： 本发明提供一种表面活性剂，其包含至少一种选自下式表示的海藻糖-6-脂肪酸酯：其中R表示具有8-22个碳原子的饱和或不饱和酰基，并且可具有羟基或其它取代基 和包含所述表面活性剂和水溶性聚合物的乳液型化妆品组合物。 本发明的表面活性剂具有优异的表面活性和安全性。 此外，乳液型化妆品组合物具有优异的长期保存稳定性和感官性能，对皮肤没有刺激性，并且具有精细的表面质地的美丽外观。 此外，本发明是具有由海藻糖脂肪酸酯构成的膜壁的脂质体。 所述脂质体具有优异的化学和物理稳定性，例如长期储存稳定性。

    Surfactant, and an emulsion-type cosmetic composition and a lipsome containing said surfactant
    7.
    发明授权
    Surfactant, and an emulsion-type cosmetic composition and a lipsome containing said surfactant 失效
    表面活性剂和乳液型化妆品组合物和含有所述表面活性剂的唇膏

    公开(公告)号：US06497898B1

    公开(公告)日：2002-12-24

    申请号：US08628674

    申请日：1996-05-13

    申请人： Takeshi Ikemoto ,  Hiromi Minamino ,  Yasushi Sumida ,  Yoh-ichi Inoue

    发明人： Takeshi Ikemoto ,  Hiromi Minamino ,  Yasushi Sumida ,  Yoh-ichi Inoue

    IPC分类号： A61K9127

    CPC分类号： B01F17/0021 ,  A61K8/06 ,  A61K8/062 ,  A61K8/14 ,  A61K8/60 ,  A61K9/0014 ,  A61K9/1272 ,  A61K47/26 ,  A61Q5/02 ,  A61Q19/00 ,  A61Q19/10 ,  C07H13/02

    摘要： The invention provides a surfactant comprising at least one trehalose-6-fatty acid ester selected from those represented by the following formula: wherein R represents a saturated or unsaturated acyl group having 8-22 carbon atoms, and may have a hydroxyl group or other substituents, and an emulsion-type cosmetic composition comprising said surfactant and a water-soluble polymer. The surfactant of the invention has excellent surface activity and safety. Also, the emulsion-type cosmetic composition has excellent long-term storage stability and sensory properties, has no irritation to skin, and gives beautiful appearance with fine surface texture. Further, the invention is a liposome having a membrane wall composed of trehalose fatty acid ester. Said liposome has excellent chemical and physical stabilities such as long-term storage stability.

    摘要翻译： 本发明提供一种表面活性剂，其包含至少一种选自下式表示的海藻糖-6-脂肪酸酯：其中R表示具有8-22个碳原子的饱和或不饱和酰基，并且可具有羟基或其它取代基 和包含所述表面活性剂和水溶性聚合物的乳液型化妆品组合物。 本发明的表面活性剂具有优异的表面活性和安全性。 此外，乳液型化妆品组合物具有优异的长期保存稳定性和感官性能，对皮肤没有刺激性，并且具有精细的表面质地的美丽外观。 此外，本发明是具有由海藻糖脂肪酸酯构成的膜壁的脂质体。 所述脂质体具有优异的化学和物理稳定性，例如长期储存稳定性。

    Creamy or milky skin cosmetic compositions
    8.
    发明授权
    Creamy or milky skin cosmetic compositions 失效
    奶油或乳状皮肤化妆品组合物

    公开(公告)号：US4424204A

    公开(公告)日：1984-01-03

    申请号：US241525

    申请日：1981-03-09

    申请人： Hiromi Minamino ,  Mitsuo Kondo ,  Yasuhisa Otani ,  Akira Miyashita ,  Kenzo Okada ,  Takashi Kuramoto

    发明人： Hiromi Minamino ,  Mitsuo Kondo ,  Yasuhisa Otani ,  Akira Miyashita ,  Kenzo Okada ,  Takashi Kuramoto

    IPC分类号： A61K8/63 ,  A61Q1/02 ,  A61Q19/00 ,  A61Q19/10 ,  A61K7/021 ,  B01J13/00 ,  C07G3/00 ,  C07H15/00

    CPC分类号： A61K8/63 ,  A61Q1/02 ,  A61Q19/00 ,  A61Q19/10 ,  A61K2800/75 ,  Y10S514/845 ,  Y10S514/939 ,  Y10S514/943

    摘要： Disclosed is a creamy or milky skin cosmetic composition which contains an emulsifying agent comprising an 18.alpha.-glycyrrhizin (18.alpha.-glycyrrhizic acid or its sodium, potassium or ammonium salt) that is a novel compound derived from a conventional glycyrrhizin (i.e., any form of 18.beta.-glycyrrhizin extracted from licorice root) or a glycyrrhizin composition consisting of an 18.alpha.-glycyrrhizin and an 18.beta.-glycyrrhizin. This skin cosmetic composition causes no irritation to the skin and hence has great safety for the skin, as contrasted with skin cosmetic compositions using synthetic emulsifiers. Moreover, it exhibits very good emulsion stability and storage stability and presents a very attractive appearance (fine texture and good gloss) owing to the unique effects of the 18.alpha.-glycyrrhizin. In particular, this skin cosmetic composition is characterized in that the difficulties inherent in the use of an emulsifying agent comprising an 18.beta.-glycyrrhizin alone (i.e., the fact that the resulting emulsion is subject to gelation, requires a long time for defoaming, and may undergo a considerable change in viscosity when transferred by the application of a shear stress) are overcome.

    摘要翻译： 公开了一种乳状或乳状皮肤化妆品组合物，其含有包含18α-甘草酸（18α-甘草酸或其钠，钾或铵盐）的乳化剂，其为衍生自常规甘草酸的新型化合物（即任何形式 由甘草根提取的18β-甘草甜素）或由18α-甘草甜素和18β-甘草甜素组成的甘草甜素组合物。 与使用合成乳化剂的皮肤化妆品组合物相比，该皮肤化妆品组合物对皮肤没有刺激性，因此对皮肤具有很高的安全性。 此外，由于18α-甘草甜素的独特作用，它表现出非常好的乳液稳定性和储存稳定性，并且呈现出非常有吸引力的外观（细纹理和良好的光泽）。 特别地，这种皮肤化妆品组合物的特征在于，使用包含单独的18β-甘草甜素的乳化剂所固有的困难（即所得乳液经历凝胶化的事实需要长时间的消泡，和 克服了通过施加剪切应力转移时可能经历显着的粘度变化）。