公开(公告)号：US06228841B1

公开(公告)日：2001-05-08

申请号：US09029604

申请日：1998-04-28

申请人： Shinobu Sakurada ,  Toru Okayama ,  Eriko Nukui ,  Kazuya Hongo ,  Tadashi Ogawa ,  Tomoko Hongo ,  Satoko Takeshima ,  Nobuhiro Take ,  Masaharu Nakano

发明人： Shinobu Sakurada ,  Toru Okayama ,  Eriko Nukui ,  Kazuya Hongo ,  Tadashi Ogawa ,  Tomoko Hongo ,  Satoko Takeshima ,  Nobuhiro Take ,  Masaharu Nakano

IPC分类号： A61K3807

CPC分类号： C07K7/02 ,  A61K38/00 ,  C07K5/0202

摘要： Compounds represented by the following general formula and salts thereof; Y-L-Tyr-Q-NR1—CH(R2)—CO—X, wherein R1 represents hydrogen or C1-6 alkyl; R2 represents optionally substituted benzyl; Q represents D- or L-Arg; Y represents two hydrogen atoms of N-terminal amino group of L-Tyr, or one or two functional groups substituting for the hydrogen atoms, for example, a C1-6 alkyl optionally having amino or carboxy; and X represents N-methyl-&bgr;-alanine and other. The compounds have analgesic effect and can be used for the treatment of cancer pain or the like.

摘要翻译： 由以下通式表示的化合物及其盐; Y-L-Tyr-Q-NR1-CH（R2）-CO-X，其中R1表示氢或C1-6烷基; R2代表任选取代的苄基; Q表示D-或L-Arg; Y代表L-Tyr的N末端氨基的两个氢原子，或一个或两个取代氢原子的官能团，例如任选具有氨基或羧基的C 1-6烷基; X表示N-甲基-β-丙氨酸等。 这些化合物具有镇痛作用，可用于治疗癌症疼痛等。

公开(公告)号：US6051685A

公开(公告)日：2000-04-18

申请号：US145648

申请日：1998-09-02

申请人： Shinobu Sakurada ,  Kimie Murayama ,  Masaharu Nakano ,  Kazuya Hongo ,  Satoko Takeshima ,  Nobuhiro Take

发明人： Shinobu Sakurada ,  Kimie Murayama ,  Masaharu Nakano ,  Kazuya Hongo ,  Satoko Takeshima ,  Nobuhiro Take

IPC分类号： C07K5/087 ,  A61K38/06

CPC分类号： C07K5/0812

摘要： A peptide derivative having analgesic activity represented by the following Formula I: ##STR1## wherein Q represents D-Arg or L-Arg; and X represents for example NR.sup.6 --CHR.sup.7 R.sup.8. Typical compounds include H.sub.2 NC(NH)-Tyr-D-Arg-Phe-NHCH.sub.2 CH.sub.2 COOH and H.sub.2 NC(NH)-Tyr-D-Arg-Phe-NHCH.sub.2 CH.sub.2 CONH.sub.2.

摘要翻译： 具有由下式I表示的止痛活性的肽衍生物：其中Q表示D-Arg或L-Arg; X表示例如NR 6 -CHR 7 R 8。 典型的化合物包括H2NC（NH）-Tyr-D-Arg-Phe-NHCH2CH2COOH和H2NC（NH）-Tyr-D-Arg-Phe-NHCH2CH2CONH2。

公开(公告)号：US08655220B2

公开(公告)日：2014-02-18

申请号：US12247794

申请日：2008-10-08

申请人： Masahiro Iwasaki ,  Katsumi Nukada ,  Wataru Yamada ,  Kenta Ide ,  Hirofumi Nakamura ,  Mitsuhide Nakamura ,  Koji Bando ,  Kaori Iemula ,  Kazuya Hongo ,  Yasuhiro Nida

发明人： Masahiro Iwasaki ,  Katsumi Nukada ,  Wataru Yamada ,  Kenta Ide ,  Hirofumi Nakamura ,  Mitsuhide Nakamura ,  Koji Bando ,  Kaori Iemula ,  Kazuya Hongo ,  Yasuhiro Nida

IPC分类号： G03G21/18

CPC分类号： G03G5/076 ,  G03G5/0612 ,  G03G5/064 ,  G03G5/07 ,  G03G5/071 ,  G03G5/075 ,  G03G5/14769

摘要： An electrophotographic photoreceptor including a conductive substrate and a photosensitive layer provided on a surface of the conductive substrate, an outermost layer of the photosensitive layer containing a crosslinked product formed from at least one charge transporting material having at least one substituent selected from the group consisting of —OH, —OCH3, —NH2, —SH, and —COOH and at least one selected from a guanamine compound or a melamine compound, the content of the at least one charge transporting material being at least about 90% by weight, and the content of the at least one selected from the guanamine compound or the melamine compound being from about 0.1% by weight to about 5% by weight.

摘要翻译： 一种电子照相感光体，包括导电基底和设置在导电基底表面上的感光层，感光层的最外层含有由至少一种电荷输送材料形成的交联产物，该电荷输送材料具有至少一个选自以下的取代基： -OH，-OCH 3，-NH 2，-SH和-COOH和选自胍胺化合物或三聚氰胺化合物中的至少一种，所述至少一种电荷输送材料的含量为至少约90重量％，并且 从胍胺化合物或三聚氰胺化合物中选出的至少一种的含量为约0.1重量％至约5重量％。

公开(公告)号：US07968264B2

公开(公告)日：2011-06-28

申请号：US12073441

申请日：2008-03-05

申请人： Kazuya Hongo ,  Yukiko Kamijo

发明人： Kazuya Hongo ,  Yukiko Kamijo

IPC分类号： G03G5/00

CPC分类号： G03G5/047 ,  G03G5/0514 ,  G03G5/0567 ,  G03G5/0592 ,  G03G5/0696 ,  G03G2215/00957

摘要： An electrophotographic photoreceptor includes a conductive substrate; and a photosensitive layer that includes a phthalocyanine pigment, a charge-transporting substance and at least one kind of lignophenol derivative.

摘要翻译： 电子照相感光体包括导电性基板; 以及包含酞菁颜料，电荷输送物质和至少一种木酚酚衍生物的感光层。

公开(公告)号：US07770738B2

公开(公告)日：2010-08-10

申请号：US12391694

申请日：2009-02-24

申请人： Kazuaki Tabata ,  Hiroshi Kojima ,  Kazuya Hongo ,  Takayuki Yamada ,  Seiichi Takagi ,  Tetsuo Ohta ,  Masaki Hirota

发明人： Kazuaki Tabata ,  Hiroshi Kojima ,  Kazuya Hongo ,  Takayuki Yamada ,  Seiichi Takagi ,  Tetsuo Ohta ,  Masaki Hirota

IPC分类号： B07B13/00 ,  B07C5/12

CPC分类号： G01N15/042 ,  G01N15/0272

摘要： A classifying device for classifying particles using a centrifugal force contains a microchannel includes a curved portion including a first tubular channel and a second tubular channel; and a diaphragm that is provided within the curved portion, and that is located at a position between the first tubular channel and the second tubular channel; and wherein the diaphragm has at least a first apertured group formed in a central region of the diaphragm and a second apertured group formed in a first end region and a second end region of the diaphragm, the first apertured group and the second apertured group communicate the first tubular channel with the second tubular channel along a direction of the centrifugal force, the first apertured group has a mesh, and the second apertured group has a mesh that is different in size from the mesh of the first apertured group.

摘要翻译： 使用离心力分级颗粒的分选装置包括微通道，其包括包括第一管状通道和第二管状通道的弯曲部分; 以及设置在所述弯曲部分内并且位于所述第一管状通道和所述第二管状通道之间的位置处的隔膜; 并且其中所述隔膜具有形成在所述隔膜的中心区域中的至少第一有孔组，以及形成在所述隔膜的第一端部区域和第二端部区域中的第二有孔组，所述第一开孔组和所述第二有孔组件将 第一管状通道，其具有沿离心力方向的第二管状通道，第一有孔组具有网状物，第二有孔组具有与第一有孔组的网格尺寸不同的网格。

公开(公告)号：US5153085A

公开(公告)日：1992-10-06

申请号：US776698

申请日：1991-10-16

申请人： Yutaka Akasaki ,  Hidekazu Aonuma ,  Kazuya Hongo ,  Katsuhiro Sato ,  Katsumi Nukada ,  Teruumi Marumo

发明人： Yutaka Akasaki ,  Hidekazu Aonuma ,  Kazuya Hongo ,  Katsuhiro Sato ,  Katsumi Nukada ,  Teruumi Marumo

IPC分类号： G03G5/06

CPC分类号： G03G5/0611 ,  G03G5/0609 ,  G03G5/0612 ,  G03G5/0618 ,  G03G5/0637 ,  G03G5/0657 ,  G03G5/0661 ,  G03G5/0696 ,  Y10S430/10

摘要： An electrophotographic photosensitive member has a charge-generating layer which includes selected photosensitive pigment particles and a compound which is a tetracyanoanthraquinodimethane compound, an anthraquinone compound, a dicyanovinyl compound, or a special quinone compound. The compound is incorporated in an amount in a range from 0.01 to 2 molar equivalents, preferably 0.1 to 1 molar equivalent, to the pigment, which has a positive hole transporting property. The photossensitive member has a charge-transporting layer and can also have a protective layer. The pigment is a phthalocyanine series pigment, a squearyrium series p igment, or a perylene series pigment. A process of using the photosensitive member includes reversal development and multicolor toner transfer. It is found that the process is adaptable to change in size of the transfer medium.

摘要翻译： 电子照相感光构件具有电荷产生层，其包含选择的感光颜料颗粒和作为四氰基蒽醌二甲烷化合物，蒽醌化合物，二氰基乙烯基化合物或特殊醌化合物的化合物。 该化合物的掺入量为0.01至2摩尔当量，优选0.1至1摩尔当量，具有空穴传输性能的颜料。 感光部件具有电荷输送层，也可以具有保护层。 该颜料是酞菁系列颜料，rium系列颜料或苝系颜料。 使用感光构件的方法包括反转显影和多色调色剂转印。 发现该过程适应于转印介质尺寸的变化。

公开(公告)号：US08679336B2

公开(公告)日：2014-03-25

申请号：US12422528

申请日：2009-04-13

申请人： Kazuya Hongo ,  Takayuki Yamada ,  Seiichi Takagi ,  Hiroshi Kojima ,  Masaki Hirota ,  Kazuaki Tabata ,  Tetsuo Ohta

发明人： Kazuya Hongo ,  Takayuki Yamada ,  Seiichi Takagi ,  Hiroshi Kojima ,  Masaki Hirota ,  Kazuaki Tabata ,  Tetsuo Ohta

IPC分类号： B01D63/08 ,  B01D61/18 ,  G05B7/04

CPC分类号： B01D63/082 ,  B01D69/10 ,  B01D71/022 ,  B01D2313/086 ,  B01D2325/021 ,  B01L3/502753 ,  B33Y80/00 ,  Y10T137/2224

摘要： A microchannel device is provided, the microchannel device containing a microfluidic channel including a sub fluidic channel in which at least one filtration diaphragm is provided, wherein the microfluidic channel has at least a supply port, a first discharge port and a second discharge port, the supply port and the first discharge port are connected through the filtration diaphragm, the supply port and the second discharge port are connected without the filtration diaphragm, and the filtration diaphragm is provided parallel to a fluidic channel direction of the microfluidic channel.

摘要翻译： 提供了一种微通道装置，所述微通道装置包含微流体通道，所述微流体通道包括其中设置有至少一个过滤隔膜的副流体通道，其中所述微流体通道至少具有供给口，第一排出口和第二排出口， 供给口和第一排出口通过过滤膜连接，供给口和第二排出口连接而不需要过滤隔膜，并且过滤隔膜平行于微流体通道的流体通道方向设置。

公开(公告)号：US08426099B2

公开(公告)日：2013-04-23

申请号：US13478730

申请日：2012-05-23

申请人： Tomohito Nakajima ,  Hiroyuki Moriya ,  Hideya Katsuhara ,  Seiichi Takagi ,  Kazuya Hongo

发明人： Tomohito Nakajima ,  Hiroyuki Moriya ,  Hideya Katsuhara ,  Seiichi Takagi ,  Kazuya Hongo

IPC分类号： G03G9/08

CPC分类号： C08J3/16 ,  C08J3/21 ,  G03G9/0804 ,  G03G9/0819 ,  G03G9/0825 ,  G03G9/0827

摘要： Colored resin particles, each includes: a resin; and a colorant, wherein a value of average equivalent circle diameter A (μm) of the colored resin particles is 3≦A≦6, an average degree of circularity B of the colored resin particles satisfies the following expression (1), and 0.990−0.0083A≦B≦1.021−0.0117A  (1) a cumulative number frequency of particles which have degrees of circularity of less than 0.9 in the colored resin particles is 1% or less.

摘要翻译： 有色树脂颗粒各自包括：树脂; 和着色树脂颗粒的平均当量圆直径A（母体）的值为3≤A@ 6的着色剂，着色树脂颗粒的平均圆形度B满足下式（1），并且0.990- 0.0083A @ B @ 1.021-0.0117A（1）着色树脂颗粒中圆度小于0.9的颗粒的累积数频率为1％以下。

公开(公告)号：US08360243B2

公开(公告)日：2013-01-29

申请号：US12730830

申请日：2010-03-24

申请人： Takayuki Yamada ,  Hiroshi Kojima ,  Kazuaki Tabata ,  Masaki Hirota ,  Kazuya Hongo

发明人： Takayuki Yamada ,  Hiroshi Kojima ,  Kazuaki Tabata ,  Masaki Hirota ,  Kazuya Hongo

IPC分类号： B07B9/00

CPC分类号： B03B5/64 ,  B03B5/00

摘要： A liquid transporting apparatus includes: a microchannel; a transporting liquid supply port through which transporting liquid is supplied to the microchannel; a partition wall as defined herein, and that has an opening; a first split channel that is provided on an upper side of the partition wall; a second split channel that is provided on a lower side of the partition wall; a particle dispersion supply port through which a particle dispersion is supplied to a middle portion of a width direction of the first split channel; and at least one drain port through which the fluid is discharged from downstreams of the first and second split channels, and a pattern that generates an upward-directed flow with respect to a vertical direction in a middle portion of a section of the microchannel is formed in an inner wall of the microchannel or in the partition wall.

摘要翻译： 液体输送装置包括：微通道; 输送液体供给到微通道的输送液供给口; 如本文所定义的分隔壁，并且具有开口; 第一分割通道，设置在分隔壁的上侧; 第二分割通道，设置在分隔壁的下侧; 粒子色散供给口，通过该粒子色散供给口向第一分割通道的宽度方向的中间部分供给粒子分散液; 以及至少一个排出口，流体从第一和第二分流通道的下游排出，并且形成在微通道的截面的中间部分中相对于垂直方向产生向上流动的图案 在微通道的内壁或分隔壁中。

公开(公告)号：US08087515B2

公开(公告)日：2012-01-03

申请号：US12397714

申请日：2009-03-04

申请人： Hiroshi Kojima ,  Kazuya Hongo ,  Seiichi Takagi ,  Tetsuo Ohta

发明人： Hiroshi Kojima ,  Kazuya Hongo ,  Seiichi Takagi ,  Tetsuo Ohta

IPC分类号： B03B5/00

CPC分类号： B03B5/36 ,  B01L3/502753 ,  B03B5/00 ,  B03B5/623 ,  B03B5/66 ,  B33Y80/00 ,  G01N15/0255

摘要： A separation apparatus contains: a dispersion liquid introduction path to which a dispersion liquid containing particles is introduced; a separation path that has a inclined upper face inclined with respect to a direction of gravity and separates the particles; and a discharge path from which particles separated by the separation path are discharged.

摘要翻译： 分离装置包括：引入含有颗粒的分散液的分散液引入路径; 分离路径，其具有相对于重力方向倾斜的倾斜上表面并分离所述颗粒; 以及排出由分离路径分离的粒子的排出路径。