公开(公告)号：US08414873B2

公开(公告)日：2013-04-09

申请号：US12602976

申请日：2008-10-10

申请人： Shixuan Zhang ,  Jinghan Sui ,  Hong Zhao ,  Dazhi Yang

发明人： Shixuan Zhang ,  Jinghan Sui ,  Hong Zhao ,  Dazhi Yang

IPC分类号： A61K31/74 ,  A61K9/00 ,  A61F2/00 ,  A01N25/00

CPC分类号： A61L31/16 ,  A61L31/022 ,  A61L31/10 ,  A61L2300/256 ,  A61L2420/06 ,  C08L5/08

摘要： A blood vessel metal stent coating of amidoglucosan polysaccharide loaded with antibody comprises carrier material composed of chitosan and inartificial degradable acidic amidoglucosan polysaccharide and the effective dose of CD133 antibody loaded in the carrier material. The blood vessel metal stent coating is manufactured with self-assemble method to fix the CD133 antibody in the carrier material of the coating. The coating has good biocompatibility, water retention property, flexibility, flush resistance and bio-stability, and can specifically capture the vascular endothelial progenitor cells in human peripheral blood, and differentiate into vascular endothelial cells. The process would accelerate endothelialization to repair injured vessel caused and prevent restenosis and thrombosis efficiently.

摘要翻译： 负载抗体的酰胺葡聚糖多糖的血管金属支架涂层包括由壳聚糖和人造可降解的酸性糖胺聚糖多糖组成的载体材料，并载入载体材料中的有效剂量的CD133抗体。 使用自组装方法制造血管金属支架涂层，以将CD133抗体固定在涂层的载体材料中。 该涂层具有良好的生物相容性，保水性，柔韧性，冲洗性和生物稳定性，并且可以特异性捕获人外周血中的血管内皮祖细胞，并分化成血管内皮细胞。 该过程将加速内皮化修复损伤的血管，并有效预防再狭窄和血栓形成。

公开(公告)号：US20100215712A1

公开(公告)日：2010-08-26

申请号：US12602976

申请日：2008-10-10

申请人： Shixuan Zhang ,  Jinghan Sui ,  Hong Zhao ,  Dazhi Yang

发明人： Shixuan Zhang ,  Jinghan Sui ,  Hong Zhao ,  Dazhi Yang

IPC分类号： A61K39/395 ,  A61F2/04 ,  A61P9/00

CPC分类号： A61L31/16 ,  A61L31/022 ,  A61L31/10 ,  A61L2300/256 ,  A61L2420/06 ,  C08L5/08

摘要： A blood vessel metal stent coating of amidoglucosan polysaccharide loaded with antibody comprises carrier material composed of chitosan and inartificial degradable acidic amidoglucosan polysaccharide and the effective dose of CD133 antibody loaded in the carrier material. The blood vessel metal stent coating is manufactured with self-assemble method to fix the CD133 antibody in the carrier material of the coating. The coating has good biocompatibility, water retention property, flexibility, flush resistance and bio-stability, and can specifically capture the vascular endothelial progenitor cells in human peripheral blood, and differentiate into vascular endothelial cells. The process would accelerate endothelialization to repair injured vessel caused and prevent restenosis and thrombosis efficiently.

摘要翻译： 负载抗体的酰胺葡聚糖多糖的血管金属支架涂层包括由壳聚糖和人造可降解的酸性糖胺聚糖多糖组成的载体材料，并载入载体材料中的有效剂量的CD133抗体。 使用自组装方法制造血管金属支架涂层，以将CD133抗体固定在涂层的载体材料中。 该涂层具有良好的生物相容性，保水性，柔韧性，冲洗性和生物稳定性，并且可以特异性捕获人外周血中的血管内皮祖细胞，并分化成血管内皮细胞。 该过程将加速内皮化修复损伤的血管，并有效预防再狭窄和血栓形成。

公开(公告)号：US09623442B2

公开(公告)日：2017-04-18

申请号：US13451391

申请日：2012-04-19

申请人： Varun Sambhy ,  Kock-Yee Law ,  Hong Zhao ,  Darren Smith

发明人： Varun Sambhy ,  Kock-Yee Law ,  Hong Zhao ,  Darren Smith

IPC分类号： B05D5/08 ,  B41J2/165 ,  B41J2/14 ,  C08G18/50 ,  C08G18/79 ,  C09D5/00 ,  C09D11/30 ,  C09D175/04 ,  C09D183/10

CPC分类号： B05D5/083 ,  B41J2/1433 ,  B41J2/1606 ,  B41J2/165 ,  C08G18/5015 ,  C08G18/792 ,  C09D5/00 ,  C09D11/30 ,  C09D175/04 ,  C09D183/10

摘要： A coating for an ink jet printhead front face, wherein the coating comprises an oleophobic low adhesion coating having high thermal stability as indicated by less than about 15 percent weight loss when heated to up to 300° C., and wherein a drop of ultra-violet (UV) gel ink or a drop of solid ink exhibits a contact angle of greater than about 50° and sliding angle of less than about 30° with a surface of the coating, wherein the coating maintains the contact angle and sliding angle after the coating has been exposed to a temperature of at least 260° C. for at least 30 minutes.

公开(公告)号：US09096062B2

公开(公告)日：2015-08-04

申请号：US13195186

申请日：2011-08-01

申请人： James M. Casella ,  Peter M. Gulvin ,  Varun Sambhy ,  Kock-Yee Law ,  Hong Zhao

发明人： James M. Casella ,  Peter M. Gulvin ,  Varun Sambhy ,  Kock-Yee Law ,  Hong Zhao

IPC分类号： B41J2/16 ,  B41J2/14

CPC分类号： B41J2/162 ,  B41J2/1433 ,  B41J2/16 ,  B41J2/1606 ,  B41J2/1623 ,  B41J2/1639 ,  Y10T29/49126 ,  Y10T29/49401

摘要： A method for forming an ink jet printhead can include interposing a coverlay between a press plate of a press and an ink jet printhead aperture plate assembly, such that the coverlay physically contacts an anti-wetting coating on a surface of the aperture plate assembly. With the coverlay contacting the anti-wetting coating, a force is applied to the aperture plate assembly using the press. The coverlay is separated from the aperture plate assembly, wherein the coverlay includes a layer having an elastic modulus of at least 0.5 GPa.

摘要翻译： 用于形成喷墨打印头的方法可以包括在压机的压板和喷墨打印头孔板组件之间插入覆盖物，使得覆盖物物理地接触孔板组件的表面上的防湿涂层。 随着覆盖层与防湿涂层接触，使用压机将力施加到孔板组件。 覆盖层与孔板组件分离，其中覆盖层包括具有至少0.5GPa的弹性模量的层。

公开(公告)号：US08933030B2

公开(公告)日：2015-01-13

申请号：US13579685

申请日：2011-02-17

申请人： Angelika Fretzen ,  Hong Zhao ,  Marco Kessler

发明人： Angelika Fretzen ,  Hong Zhao ,  Marco Kessler

IPC分类号： A61K38/00 ,  A61P1/04 ,  A61K38/12 ,  A61K38/04 ,  C07K5/00 ,  C07K7/00 ,  C07K16/00 ,  C07K17/00 ,  C07K7/08 ,  A61K38/10 ,  A61K45/06

CPC分类号： C07K7/08 ,  A61K38/08 ,  A61K38/10 ,  A61K45/06 ,  C07K7/06

摘要： The present invention features peptides, compositions, and related methods for treating gastrointestinal disorders and conditions, including but not limited to, irritable bowel syndrome (IBS), gastrointestinal motility disorders, functional gastrointestinal disorders, gastroesophageal reflux disease (GERD), duodenogastric reflux, Crohn's disease, ulcerative colitis, inflammatory bowel disease, functional heartburn, dyspepsia, visceral pain, gastroparesis, chronic intestinal pseudo-obstruction (or colonic pseudo-obstruction), disorders and conditions associated with constipation, and other conditions and disorders are described herein, using peptides and other agents that activate the guanylate cyclase C (GC-C) receptor.

摘要翻译： 本发明涉及用于治疗胃肠道疾病和病症的肽，组合物和相关方法，包括但不限于肠易激综合征（IBS），胃肠蠕动障碍，功能性胃肠道疾病，胃食管反流病（GERD），十二指肠胃反流，克罗恩氏病 疾病，溃疡性结肠炎，炎性肠病，功能性胃灼热，消化不良，内脏痛，胃轻瘫，慢性肠假性梗阻（或结肠假性梗阻），与便秘相关的病症和病症以及其它病症和病症在本文中用肽描述 和激活鸟苷酸环化酶C（GC-C）受体的其它试剂。

公开(公告)号：US08708458B2

公开(公告)日：2014-04-29

申请号：US13209836

申请日：2011-08-15

申请人： Hong Zhao ,  Kock-Yee Law ,  Yuanjia Zhang

发明人： Hong Zhao ,  Kock-Yee Law ,  Yuanjia Zhang

IPC分类号： B41J2/135

CPC分类号： G11B5/743 ,  B41J2/1433 ,  B41J2/1606 ,  C03C15/00 ,  C03C17/28 ,  C03C2217/76

摘要： Various embodiments provide materials and methods for a superoleophobic device, which can include a conformal oleophobic coating disposed on glass pillars and/or stripe-shaped glass structures on a glass substrate to provide the device with a textured superoleophobic surface.

摘要翻译： 各种实施方案提供了用于超疏油装置的材料和方法，其可以包括设置在玻璃基板上的玻璃柱和/或条形玻璃结构上的保形疏油涂层，以为该装置提供织构化的超疏油表面。

公开(公告)号：US08682388B2

公开(公告)日：2014-03-25

申请号：US12983121

申请日：2010-12-31

申请人： Sandeep Vuppu ,  Chris Grivas ,  Hong Zhao

发明人： Sandeep Vuppu ,  Chris Grivas ,  Hong Zhao

IPC分类号： H04W88/02

CPC分类号： H04W52/027 ,  G06F1/3231 ,  G06F3/012 ,  G06F3/0488 ,  H04M2250/12 ,  H04M2250/22 ,  H04M2250/52 ,  Y02D10/173 ,  Y02D70/1224 ,  Y02D70/1242 ,  Y02D70/1262 ,  Y02D70/142 ,  Y02D70/144 ,  Y02D70/146 ,  Y02D70/164

摘要： A mobile device includes a touch screen display and touch screen circuit for receiving touch inputs. A camera configured to acquire one or more images in front of the display. A proximity sensor configured to provide an indication that a user is in close proximity to the touch screen display. A processor being effective to determine, in response to the indication of the proximity sensor, whether the user is in a position to view the display based on the one or more images of the camera. If the proximity sensor provides an indication that the user is in close proximity to the display and the processor determines, based on the one or more images, that the user is in a position to view the display, then at least one of the display and the touch screen circuit are not disabled.

摘要翻译： 移动设备包括用于接收触摸输入的触摸屏显示器和触摸屏电路。 配置为获取显示器前面的一个或多个图像的相机。 接近传感器，被配置为提供用户紧邻触摸屏显示器的指示。 处理器有效地响应于接近传感器的指示来确定用户是否处于基于相机的一个或多个图像来观看显示器的位置。 如果接近传感器提供用户与显示器非常接近的指示，并且处理器基于一个或多个图像确定用户处于查看显示器的位置，则显示器和显示器中的至少一个 触摸屏电路不被禁用。

公开(公告)号：US20140001662A1

公开(公告)日：2014-01-02

申请号：US13980126

申请日：2011-03-25

申请人： Hong Yin ,  Jianfeng Chen ,  Zhirong Chen ,  Jiexin Wang ,  Yong Qi ,  Hong Zhao ,  Lifang Shi ,  Dan Qiu

发明人： Hong Yin ,  Jianfeng Chen ,  Zhirong Chen ,  Jiexin Wang ,  Yong Qi ,  Hong Zhao ,  Lifang Shi ,  Dan Qiu

IPC分类号： A61J3/07

CPC分类号： A61J3/07 ,  A61K9/1652 ,  A61K9/1694 ,  A61K9/5036 ,  A61K9/5089 ,  A61K9/5161 ,  A61K31/07

摘要： A method for continuously preparing stable-type vitamin A microcapsules is disclosed. The method comprises the following steps: adding vitamin A crystals and an antioxidant into a crystal melter continuously according to a certain ratio under the protection of nitrogen to prepare vitamin A melting oil containing the antioxidant; pumping the above melting oil into a high gravity rotary packed bed emulsifier with a liquid distributor by a pump, and pumping aqueous solution containing gellable modified starch into the above high gravity rotary packed bed emulsifier after deoxidation treatment to obtain vitamin A emulsion at the outlet of the high gravity rotary packed bed emulsifier; and atomizing and spraying the emulsion continuously in a cooled starch bed for granulating, and performing fluidization drying and gelation treatment in a fluidized bed by taking nitrogen as a drying medium to obtain the stable-type vitamin A microcapsules. Above method has the advantage of capability of continuous production, and has good embedding effect due to adopting the gellable modified starch, granulating and gelation treatment, thus the product has good storage stability.

摘要翻译： 公开了连续制备稳定型维生素A微胶囊的方法。 该方法包括以下步骤：在氮保护下，以一定的比例将维生素A晶体和抗氧化剂连续添加到晶体熔化器中，制备含有抗氧化剂的维生素A熔融油; 通过泵将上述熔融油泵送到具有液体分配器的高重力旋转填充床乳化剂中，并且在脱氧处理之后将含有可凝胶改性淀粉的水溶液泵送到上述高重力旋转填充床乳化剂中以在出口处获得维生素A乳液 高重力旋转填充床乳化剂; 并在冷却的淀粉床中连续雾化和喷雾乳液进行造粒，并通过以氮气作为干燥介质在流化床中进行流化干燥和凝胶化处理，得到稳定型维生素A微胶囊。 上述方法具有连续生产能力的优点，由于采用可凝胶改性淀粉，造粒和凝胶化处理，具有良好的包埋效果，因此产品具有良好的储存稳定性。

公开(公告)号：US08593070B2

公开(公告)日：2013-11-26

申请号：US13128936

申请日：2010-07-26

申请人： Jian Wang ,  Hong Zhao

发明人： Jian Wang ,  Hong Zhao

IPC分类号： H05B37/00 ,  H02M7/00

CPC分类号： H05B33/0815

摘要： A three phase rectifier rectifies received three phase a.c. power to generate a ripple d.e. voltage. A power distribution bus conveys distribution power comprising the ripple d.c. voltage or an a.c. voltage derived therefrom to a location of an LED based lamp that is distal from the three phase rectifier. Additional circuitry disposed with the LED based lamp drives the LED based lamp using the distribution power.

摘要翻译： 三相整流器对接收的三相交流整流器进行整流。 产生波纹的能力 电压。 配电总线传送包括波纹直流的配电功率。 电压或电流 电压源于距离三相整流器远的LED基灯的位置。 配有基于LED的灯的附加电路使用分配功率驱动基于LED的灯。

公开(公告)号：US08560092B2

公开(公告)日：2013-10-15

申请号：US12786052

申请日：2010-05-24

申请人： Qingsheng Quinn Zheng ,  Hong Zhao

发明人： Qingsheng Quinn Zheng ,  Hong Zhao

IPC分类号： G06F19/00

CPC分类号： G05B13/048

摘要： Apparatuses and methods for model quality estimation and model adaptation in multivariable process control are disclosed. A method for updating a multiple input multiple output (MIMO) dynamical model of a process includes perturbing the process, auditing the controller model, identifying poor performing submodels and re-testing the relevant process variables, re-identifying submodels and adapting the model online while the process continues to operate within normal operating parameters. An apparatus comprises an online multivariable controller, a tester, a database to store data corresponding to manipulated variables and controlled variables, and a performance diagnosis module configured to identify problematic submodels and adapt a model used by the controller.

摘要翻译： 公开了多变量过程控制中的模型质量估计和模型适应的装置和方法。 用于更新过程的多输入多输出（MIMO）动态模型的方法包括扰动过程，审核控制器模型，识别执行不良的子模型并重新测试相关过程变量，重新识别子模型并在线适配模型 该过程继续在正常操作参数内运行。 一种装置包括在线多变量控制器，测试器，用于存储与操作变量和受控变量相对应的数据的数据库，以及性能诊断模块，被配置为识别有问题的子模型并适应控制器使用的模型。