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1.发明申请公开(公告)号：US20200217915A1
公开(公告)日：2020-07-09
申请号：US16242353
申请日：2019-01-08
发明人： Xiaodong Zhong , Marcel Dominik Nickel , Stephan Kannengiesser , Brian Dale , Berthold Kiefer , Mustafa R. Bashir
IPC分类号： G01R33/56 , G01R33/563 , G01R33/565 , A61B5/055 , A61B5/00
摘要： A magnetic resonance imaging system and method are provided for improved determination of noise bias effects in calculating fitted parameters for quantitative MRI procedures. The system and method includes selecting a range for the SNR and fitted parameter values, and for each of a plurality of base pairs of these values and for a plurality of b values, adding a random noise term to the real and imaginary components of a plurality of corresponding signal terms, fitting magnitudes of the resulting “noisy” signals to determine a “noisy” fitted parameter value, and compare the “noisy” and base fitted parameter values to determine a noise-based error for each pair of base values. The noise-based errors can be used to generate an error map, modify imaging parameters to reduce such errors, or correct fitted parameters directly.
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公开(公告)号：US10460508B2
公开(公告)日：2019-10-29
申请号：US14735243
申请日：2015-06-10
发明人： Yiqiang Zhan , Gerardo Hermosillo-Valadez , Xiang Sean Zhou , Matthias Fenchel , Berthold Kiefer
摘要： A framework for facilitating visualization, including localizing at least one anatomical structure of interest in image data. The structure of interest is then highlighted by reformatting the image data by mapping landmarks associated with the structure of interest to corresponding points along a contour of a geometric shape and warping the image data based on the mapped landmarks. The resulting reformatted image data is rendered for display to a user.
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3.发明申请公开(公告)号：US20180292485A1
公开(公告)日：2018-10-11
申请号：US15946802
申请日：2018-04-06
发明人： Stephan Kannengiesser , Berthold Kiefer , Mustafa R. Bashir , Claudia Fellner , Marcel Dominik Nickel
摘要： In a magnetic resonance (MR) apparatus and a method for operating such an apparatus, a T1 parameter map is generated with fat fraction correction, by using a model in which the fat fraction of acquired MR data is used as a known parameter. The T1 values from the acquired MR data are fat fraction-corrected in such a manner, so as to generate fat fraction-corrected entries for the T1 parameter map according to the model.
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公开(公告)号：US20170307705A1
公开(公告)日：2017-10-26
申请号：US15493842
申请日：2017-04-21
发明人： John P. Mugler, III , Samuel W. Fielden , G. Wilson Miller, IV , Craig H. Meyer , Talissa A. Altes , Alto Stemmer , Josef Pfeuffer , Berthold Kiefer
摘要： Some aspects of the present disclosure relate to ultrashort-echo-time (UTE) imaging. In one embodiment, a method includes acquiring UTE imaging data associated with an area of interest of a subject. The acquiring comprises applying an imaging pulse sequence with a three-dimensional (3D) spiral acquisition and a nonselective excitation pulse. The method also includes reconstructing at least one image of the area of interest from the acquired UTE imaging data.
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5.发明申请公开(公告)号：US20170242089A1
公开(公告)日：2017-08-24
申请号：US15441288
申请日：2017-02-24
发明人： Berthold Kiefer , Alto Stemmer
IPC分类号： G01R33/565 , G01R33/561 , G01R33/44 , G01R33/56
摘要： In a method and magnetic resonance (MR) apparatus for performing an adjustment of the MR system, an examination object under is divided into at least one excitation volume. First adjustment parameters for the at least one excitation volume of the object, and second adjustment parameters for the at least one excitation volume of the object, which differ from the first adjustment parameters are determined. First MR signals are acquired from the at least one excitation volume using the first adjustment parameters. Second MR signals are acquired from an excitation volume using the second adjustment parameters. A first MR image of the at least one excitation volume is reconstructed using the first MR signal. A second MR image of the at least one excitation volume is reconstructed using the second MR signal.
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公开(公告)号：US11333734B2
公开(公告)日：2022-05-17
申请号：US16868848
申请日：2020-05-07
发明人： Xiaodong Zhong , Vibhas S. Deshpande , Marcel Dominik Nickel , Xiaoming Bi , Stephan Kannengiesser , Berthold Kiefer
IPC分类号： G01R33/567 , G01R33/56 , G06T11/00 , G06T7/00 , G06T3/00
摘要： A method of generating biomarker parameters includes acquiring imaging data depicting a patient using a MRI system. The imaging data is acquired for a plurality of contrasts resulting from application of a pulse on the patient's anatomy. A process is executed to generate a MoCoAve image for each contrast. This process includes dividing the imaging data for the contrast into bins corresponding to one of a plurality of respiratory motion phases, and reconstructing the imaging data in each bin to yield bin images. The process further includes selecting a reference bin image from the bin images, and warping the bin images based on the reference bin image. The warped bin images and the reference bin image are averaged to generate the MoCoAve image for the contrast. One or more biomarker parameter maps are calculated based on the MoCoAve images generated for the contrasts.
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7.发明授权公开(公告)号：US10436867B2
公开(公告)日：2019-10-08
申请号：US15613563
申请日：2017-06-05
IPC分类号： G01R33/50 , G01R33/341 , G01R33/483 , G01R33/56 , A61B5/055 , A61B5/00
摘要： In a computer and a magnetic resonance method and apparatus for automatic characterization (classification) of liver tissue in a region of interest of a liver, at least one value tuple of the region of interest of the liver is acquired, the value tuple including at least one T1 value determined from magnetic resonance images of the region of interest, or a reciprocal value thereof, and a T2 or T2* value or a reciprocal value thereof. The value tuple is transferred into a multidimensional parameter space and the characterization of the liver tissue is then performed on the basis of the position of the value tuple in the parameter space.
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公开(公告)号：US20180292499A1
公开(公告)日：2018-10-11
申请号：US15947443
申请日：2018-04-06
发明人： Craig H. Meyer , John P. Mugler, III , Samuel W. Fielden , Gudrun Ruyters , Berthold Kiefer , Josef Pfeuffer
IPC分类号： G01R33/561 , G01R33/565 , G01R33/48 , G01R33/563
CPC分类号： G01R33/5615 , G01R33/243 , G01R33/4818 , G01R33/4824 , G01R33/56308 , G01R33/56518 , G01R33/56563
摘要： In some aspects, the disclosed technology relates to magnetic field monitoring of spiral echo train imaging. In one embodiment, a method for spiral echo train imaging of an area of interest of a subject includes measuring k-space values and field dynamics corresponding to each echo of a spiral echo pulse train, using a dynamic field camera and a magnetic resonance imaging (MRI) system. The dynamic field camera is configured to measure characteristics of fields generated by the MRI system; the characteristics include at least one imperfection associated with the MRI system. The spiral echo pulse train corresponds to a spiral trajectory scan from the MRI system that obtains magnetic resonance imaging data using a pulse sequence which applies spiral gradients in-plane with through-plane phase encoding. The method also includes generating, based on the characteristics of the fields measured by the dynamic field camera and based on the obtained magnetic resonance imaging data, a model of the k-space trajectory corresponding to each echo of the spiral echo pulse train; and, based on the generated model of the k-space trajectory, reconstructing images that correspond to the area of interest and that are compensated for the at least one imperfection associated with the MRI system.
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公开(公告)号：US10083505B2
公开(公告)日：2018-09-25
申请号：US15613522
申请日：2017-06-05
CPC分类号： G06T7/0012 , A61B5/055 , A61B6/481 , G01R33/34092 , G01R33/4835 , G01R33/50 , G01R33/5601 , G01R33/5608 , G06T7/0014 , G06T7/0016 , G06T7/136 , G06T2207/10088 , G06T2207/30056
摘要： In a magnetic resonance method and apparatus for determination of a measurement variable that is relevant to a function of an organ of a patient, a first longitudinal relaxation rate R11 is determined before a contrast medium is administered to the patient. A second longitudinal relaxation rate R12 is determined after a contrast medium is administered to the patient. A property of the contrast medium in the organ is determined based on R11 and R12. The measurement variable is determined based on the property of the contrast medium in the organ.
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公开(公告)号：US20180240233A1
公开(公告)日：2018-08-23
申请号：US15831819
申请日：2017-12-05
IPC分类号： G06T7/00
CPC分类号： G06T7/0012 , G06T2207/10088 , G06T2207/10096 , G06T2207/20081 , G06T2207/20084 , G06T2207/30081 , G06T2207/30096
摘要： A method and apparatus for automated prostate tumor detection and classification in multi-parametric magnetic resonance imaging (MRI) is disclosed. A multi-parametric MRI image set of a patient, including a plurality of different types of MRI images, is received. Simultaneous detection and classification of prostate tumors in the multi-parametric MRI image set of the patient are performed using a trained multi-channel image-to-image convolutional encoder-decoder that inputs multiple MRI images of the multi-parametric MRI image set of the patient and includes a plurality of output channels corresponding to a plurality of different tumor classes. For each output channel, the trained image-to image convolutional encoder-decoder generates a respective response map that provides detected locations of prostate tumors of the corresponding tumor class in the multi-parametric MRI image set of the patient.
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