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公开(公告)号:US09486005B2
公开(公告)日:2016-11-08
申请号:US13580471
申请日:2011-02-22
申请人: Smiti Vaid Gupta , Enrique Martinez, II , Fazlul H. Sarkar , Denis M. Callewaert , Andreea Geamanu , Kevin Michael Patrie , Tiffany Capri Thomas , Andrew A. Dahl
发明人: Smiti Vaid Gupta , Enrique Martinez, II , Fazlul H. Sarkar , Denis M. Callewaert , Andreea Geamanu , Kevin Michael Patrie , Tiffany Capri Thomas , Andrew A. Dahl
CPC分类号: A23L33/30 , A23L33/10 , A23L33/17 , A23V2002/00 , A61K9/0053 , A61K36/02 , A23V2200/3262 , A23V2250/202
摘要: A method of treating hypercholesterolemia in mammals, by administering an effective amount of a microbial fermentation product, and regulating genes involved in lipoprotein metabolism. A method of regulating cholesterol levels in a patient by administering an effective amount of a composition chosen from the group consisting of PAZ, specific components isolated from PAZ, chemically synthesized analogs of the components of PAZ, and regulating genes involved in lipoprotein metabolism. A method of treating high cholesterol levels in an individual by administering an effective amount of a microbial fermentation product, up-regulating the expression of at least one of the genes that encode ABCA1, ApoA1, and SRB1, and down-regulating the gene that encodes CETP. A method of preventing the onset of high cholesterol levels and/or a deleterious lipoprotein profile in an individual.
摘要翻译: 通过施用有效量的微生物发酵产物和调节涉及脂蛋白代谢的基因来治疗哺乳动物中的高胆固醇血症的方法。 通过施用有效量的选自PAZ,从PAZ分离的特异性成分,化学合成的PAZ组分的类似物和调节参与脂蛋白代谢的基因的组合来调节患者胆固醇水平的方法。 通过施用有效量的微生物发酵产物来治疗个体中高胆固醇水平的方法,上调编码ABCA1,ApoA1和SRB1的至少一个基因的表达,并下调编码的基因 CETP。 一种预防个体中高胆固醇水平和/或有害脂蛋白分布发生的方法。
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公开(公告)号:US20120328598A1
公开(公告)日:2012-12-27
申请号:US13580471
申请日:2011-02-22
申请人: Smiti Vaid Gupta , Enrique Martinez , Fazlul H. Sarkar , Denis M. Callewaert , Andreea Geamanu , Kevin Michael Patrie , Tiffany Capri Thomas , Andrew A. Dahl
发明人: Smiti Vaid Gupta , Enrique Martinez , Fazlul H. Sarkar , Denis M. Callewaert , Andreea Geamanu , Kevin Michael Patrie , Tiffany Capri Thomas , Andrew A. Dahl
CPC分类号: A23L33/30 , A23L33/10 , A23L33/17 , A23V2002/00 , A61K9/0053 , A61K36/02 , A23V2200/3262 , A23V2250/202
摘要: A method of treating hypercholesterolemia in mammals, by administering an effective amount of a microbial fermentation product, and regulating genes involved in lipoprotein metabolism. A method of regulating cholesterol levels in a patient by administering an effective amount of a composition chosen from the group consisting of PAZ, specific components isolated from PAZ, chemically synthesized analogues of the components of PAZ, and regulating genes involved in lipoprotein metabolism. A method of treating high cholesterol levels in an individual by administering an effective amount of a microbial fermentation product, up-regulating the expression of at least one of the genes that encode ABCA1, ApoA1, and SRB1, and down-regulating the gene that encodes CETP. A method of preventing the onset of high cholesterol levels and/or a deleterious lipoprotein profile in an individual.
摘要翻译: 通过施用有效量的微生物发酵产物和调节涉及脂蛋白代谢的基因来治疗哺乳动物中的高胆固醇血症的方法。 通过施用有效量的选自PAZ,从PAZ分离的特异性成分,化学合成的PAZ组分的类似物和调节参与脂蛋白代谢的基因的组合物来调节患者胆固醇水平的方法。 通过施用有效量的微生物发酵产物来治疗个体中高胆固醇水平的方法,上调编码ABCA1,ApoA1和SRB1的至少一个基因的表达,并下调编码的基因 CETP。 一种预防个体中高胆固醇水平和/或有害脂蛋白分布发生的方法。
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公开(公告)号:US20170135391A1
公开(公告)日:2017-05-18
申请号:US15330830
申请日:2016-11-07
CPC分类号: A23L33/30 , A23L33/10 , A23L33/17 , A23V2002/00 , A61K9/0053 , A61K36/02 , A23V2200/3262 , A23V2250/202
摘要: A method of treating hypercholesterolemia in mammals, by administering an effective amount of a microbial fermentation product, and regulating genes involved in lipoprotein metabolism. A method of regulating cholesterol levels in a patient by administering an effective amount of a composition chosen from the group consisting of PAZ, specific components isolated from PAZ, chemically synthesized analogues of the components of PAZ, and regulating genes involved in lipoprotein metabolism. A method of treating high cholesterol levels in an individual by administering an effective amount of a microbial fermentation product, up-regulating the expression of at least one of the genes that encode ABCA1, ApoA1, and SRB1, and down-regulating the gene that encodes CETP. A method of preventing the onset of high cholesterol levels and/or a deleterious lipoprotein profile in an individual.
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公开(公告)号:US10161928B2
公开(公告)日:2018-12-25
申请号:US13812220
申请日:2011-07-21
摘要: A panel for monitoring levels of biomarkers, including an assay having at least one inflammation monitoring test, at least one oxidative stress monitoring test, and at least one antioxidant activity monitoring test. A method of monitoring an individual's health, by collecting a sample from the individual, applying the sample to an assay panel, performing at least one inflammation monitoring test, at least one oxidative stress monitoring test, and at least one antioxidant activity monitoring test in the panel, and determining levels of biomarkers related to inflammation, oxidative stress, and antioxidant activity and therefore providing information regarding the individual's relative health and/or risk of developing one or more diseases.
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公开(公告)号:US20130122518A1
公开(公告)日:2013-05-16
申请号:US13812220
申请日:2011-07-21
CPC分类号: G01N33/50 , G01N33/53 , G01N33/6893 , G01N2800/7009 , G01N2800/7095 , Y10T436/173076
摘要: A panel for monitoring levels of biomarkers, including an assay having at least one inflammation monitoring test, at least one oxidative stress monitoring test, and at least one antioxidant activity monitoring test. A method of monitoring an individual's health, by collecting a sample from the individual, applying the sample to an assay panel, performing at least one inflammation monitoring test, at least one oxidative stress monitoring test, and at least one antioxidant activity monitoring test in the panel, and determining levels of biomarkers related to inflammation, oxidative stress, and antioxidant activity and therefore providing information regarding the individual's relative health and/or risk of developing one or more diseases.
摘要翻译: 用于监测生物标志物水平的小组,包括具有至少一种炎症监测试验,至少一种氧化应激监测试验和至少一种抗氧化活性监测试验的试验。 通过从个体收集样品,将样品应用于测定面板,进行至少一种炎症监测测试,至少一种氧化应激监测测试和至少一种抗氧化活性监测测试来监测个体健康的方法 并确定与炎症,氧化应激和抗氧化活性相关的生物标志物的水平,因此提供关于个体的相对健康和/或发展一种或多种疾病的风险的信息。
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公开(公告)号:US06356939B1
公开(公告)日:2002-03-12
申请号:US09189256
申请日:1998-11-10
申请人: Andrew A. Dahl
发明人: Andrew A. Dahl
IPC分类号: G06F1516
CPC分类号: H04H20/38 , G09B5/065 , G09B5/067 , G09B5/14 , H04H20/63 , H04N5/74 , H04N7/17318 , H04N7/181 , H04N21/252 , H04N21/2668 , H04N21/41415 , H04N21/4143 , H04N21/472
摘要: A interactive system (10) for presenting information to members of an audience includes a main server (11) connected to a slave server (13), a video projector (19) connected to the slaver server for displaying information to all members of an audience, a memory in the main server and a laser disc unit (21) connected to slave server for storing information related to a plurality of categories and a plurality of topics related to each of the categories, and a plurality of seat computers (16) connected through an audience response server (14) to the main server. Each seat computer generates category selection signals and topic selection signals upon actuation by an associated audience member and displays the stored information to the associated audience member. The main server (11) is responsive to the category selection signals for controlling the video projector (19) to display the stored information related to at least a first topic choice related to a first category choice of the audience on a screen (20) visible to the audience. For each audience member who did not select the first category choice, the main server (11) controls the associated seat computer to display the stored information related to another one of the categories selected by the audience member.
摘要翻译: 用于向观众的成员呈现信息的交互式系统(10)包括连接到从服务器(13)的主服务器(11),连接到从服务器的视频投影仪(19),用于向观众的所有成员显示信息 ,主服务器中的存储器和连接到从服务器的激光盘单元(21),用于存储与多个类别相关的信息和与每个类别相关的多个主题,并且多个座位计算机(16)连接 通过观众响应服务器(14)到主服务器。 每个座椅计算机在由相关观众成员启动时产生类别选择信号和主题选择信号,并将所存储的信息显示给相关联的观众。 主服务器(11)响应于用于控制视频投影仪(19)的类别选择信号,以在可见的屏幕(20)上显示与至少与观众的第一类别选择相关的至少第一主题选择相关的存储信息 给观众 对于没有选择第一类别选择的每个观众成员,主服务器(11)控制相关联的座椅计算机来显示与观众成员选择的另一类别相关的存储信息。
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公开(公告)号:US20080129484A1
公开(公告)日:2008-06-05
申请号:US11978553
申请日:2007-10-29
申请人: Andrew A. Dahl , Edward V. Keiser
发明人: Andrew A. Dahl , Edward V. Keiser
IPC分类号: G08B23/00
CPC分类号: G08B25/14
摘要: An external access station for interfacing with existing building monitoring systems to obtain data and control at least some of the systems for use by first responders to an emergency. The access station includes a protective enclosure recessed into a building exterior wall or adjacent kiosk housing a panel PC and touch screen display viewable upon opening a locked cover.
摘要翻译: 外部接入站,用于与现有建筑物监控系统接口以获得数据并控制第一响应者用于紧急情况的至少一些系统。 接入站包括凹入建筑物外墙或邻近的亭的保护壳体,其容纳面板PC和在打开锁定的盖子时可触摸屏幕显示器。
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公开(公告)号:US07719415B2
公开(公告)日:2010-05-18
申请号:US11978553
申请日:2007-10-29
申请人: Andrew A. Dahl , Edward V. Keiser
发明人: Andrew A. Dahl , Edward V. Keiser
IPC分类号: G08B25/00
CPC分类号: G08B25/14
摘要: An external access station for interfacing with existing building monitoring systems to obtain data and control at least some of the systems for use by first responders to an emergency. The access station includes a protective enclosure recessed into a building exterior wall or adjacent kiosk housing a panel PC and touch screen display viewable upon opening a locked cover.
摘要翻译: 外部接入站,用于与现有建筑物监控系统接口以获得数据并控制第一响应者用于紧急情况的至少一些系统。 接入站包括凹入建筑物外墙或邻近的亭的保护壳体,其容纳面板PC和在打开锁定的盖子时可触摸屏幕显示器。
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公开(公告)号:US5835715A
公开(公告)日:1998-11-10
申请号:US849225
申请日:1997-05-30
申请人: Andrew A. Dahl
发明人: Andrew A. Dahl
IPC分类号: G09B5/06 , G09B5/14 , H04H1/00 , H04H20/38 , H04H20/63 , H04N5/74 , H04N7/173 , H04N7/18 , H04N21/25 , H04N21/2668 , H04N21/414 , H04N21/4143 , H04N21/472 , G06F17/00
CPC分类号: H04H20/38 , G09B5/065 , G09B5/067 , G09B5/14 , H04H20/63 , H04N21/252 , H04N21/2668 , H04N21/41415 , H04N21/4143 , H04N21/472 , H04N7/17318 , H04N7/181 , H04N5/74
摘要: An interactive system (10) for presenting information to members of an audience includes a main server (11), slave server (13), a video projector (19) for displaying information to all members of an audience, a memory in the main server and a laser disc unit connected to slave server for storing information related to a plurality of categories and a plurality of topics related to each categories, and a plurality of seat computers (16) connected through an audience response server to the main server (11). The main server (11) is responsive to category selection signals for controlling the video projector (19) to display the stored information which is first category choice of the audience. For each audience member who did not select the first category choice, the main server (11) controls the associated seat computer (16) to display the stored information related to another one of the categories selected by the audience member.
摘要翻译: PCT No.PCT / US96 / 15832 Sec。 371日期1997年5月30日 102(e)日期1997年5月30日PCT提交1996年10月3日PCT公布。 公开号WO97 / 13207 日期1997年04月10日用于向观众的成员呈现信息的交互式系统(10)包括主服务器(11),从服务器(13),用于向观众的所有成员显示信息的视频投影仪(19) 主服务器中的存储器和连接到从服务器的激光盘单元,用于存储与多个类别相关的信息和与每个类别相关的多个主题;以及多个座位计算机(16),通过观众响应服务器连接到 主服务器(11)。 主服务器(11)响应于用于控制视频投影仪(19)的类别选择信号,以显示作为观众的第一类别选择的存储信息。 对于没有选择第一类别选择的每个观众成员,主服务器(11)控制相关联的座位计算机(16)显示与由观众成员选择的另一类别相关的存储信息。
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