摘要:
An optical imaging apparatus (100) for examination of an object of interest (101), the optical imaging apparatus (100) comprising an optical radiation source (102) adapted to emit a primary optical radiation beam onto the object of interest (101), an optical radiation detector (106) adapted to detect a secondary optical radiation beam emitted by the object of interest (101) upon absorbing the primary optical radiation beam, a magnetic field generating element (107) adapted to generate an inhomogeneous magnetic field varying along an extension of the object of interest (101), and a determination unit (108) adapted to determine information concerning the object of interest (101) based on an analysis of the detected secondary optical radiation beam in combination with an analysis of the inhomogeneous magnetic field.
摘要:
The present invention relates to novel methods and compounds for combined opticalultrasound imaging. The compounds of the present invention relate to particles comprising fluorescence donor and acceptor molecules for energy exchange via FRET. The methods of the present invention use ultrasound to modify the distance between donor and acceptor molecules present on the particles, and to consequently modify the fluorescence emitted by the donor and acceptor. The compounds and methods of the present invention are useful in medical or diagnostic imaging.
摘要:
A receive coil (46, 46′, 46″) receiving a magnetic resonance signal includes an optical resonant cavity (82, 82′, 82″) having an electro-optically active medium (90, 90′, 90″). A radio frequency antenna (80, 80′, 80″) is coupled with the electro-optically active medium such that reception of the magnetic resonance signal by the radio frequency antenna modulates an optical characteristic of the optical resonant cavity. An interventional instrument (48) is adapted for partial insertion into an associated imaging subject (16). The radio frequency antenna and the optical resonant cavity are disposed on a portion of the interventional instrument that is inserted into the associated imaging subject. At least one optical fiber (52, 54) is optically coupled with the optical resonant cavity. An end of the at least one optical fiber extends outside of the associated imaging subject when the interventional instrument is partially inserted.
摘要:
A medical apparatus (1100) comprising a magnetic resonance imaging system and an interventional device (300) comprising a shaft (302, 1014, 1120). The medical apparatus further comprises a toroidal magnetic resonance fiducial marker (306, 600, 800, 900, 1000, 1122) attached to the shaft. The shaft passes through a center point (610, 810, 908, 1006) of the fiducial marker. The medical apparatus further comprises machine executable instructions (1150, 1152, 1154, 1156, 1158) for execution by a processor. The instructions cause the processor to acquire (100, 200) magnetic resonance data, to reconstruct (102, 202) a magnetic resonance image (1142), and to receive (104, 204) the selection of a target volume (1118, 1144, 1168). The instructions further cause the processor to repeatedly: acquire (106, 206) magnetic resonance location data (1146) from the fiducial marker and render (108, 212) a view (1148, 1162) indicating the position of the shaft relative to the target zone.
摘要:
The invention relates to a method of characterizing the RF transmit chain of a magnetic resonance imaging scanner (1) using a local transmit/receive coil system (204; 210), comprising a first local NMR probe and a first local magnetic resonance coil, the first NMR probe being spatially located in immediate neighborhood to the first coil, a local receive coil system (206; 208), comprising a second local NMR probe and a second local magnetic resonance coil, the second NMR probe being spatially located in immediate neighborhood to the second coil, wherein the transmit chain comprises an external MR coil (9; 11; 12; 13), the method comprising: determining with the first magnetic resonance coil, a first MR signal phase evolution of the local RF transmit field generated by MR excitation of the first probe using the first magnetic resonance coil by measuring the RF response of the first probe upon said excitation, determining with the second magnetic resonance coil a second MR signal phase evolution of the local RF transmit field generated by MR excitation of the second probe using the external MR coil (9; 11; 12; 13) by measuring the RF response of the second probe upon said excitation, calculating a phase offset between the first and second MR signal phase evolution.
摘要:
A method of magnetic resolution (MR) imaging of a moving portion of a body of a patient placed in an examination volume of a MR device. For the purpose of enabling improved interventional MR imaging from acquiring a MR signal data with motion compensation, the invention proposes that the method includes repeated acts of collecting tracking data from an interventional instrument introduced into the portion of the body, subjecting the portion of the body to an imaging sequence for acquiring one or more MR signals therefrom, wherein parameters of the imaging sequence are adjusted on the basis of the tracking data, and reconstructing one or more MR images from the MR signal data set.
摘要:
An interventional or a non-interventional instrument like a catheter, a surgical device, a biopsy needle, a pointer, a stent or another invasive or non-invasive device, like a position marker, or a surface or local coil like a head coil is disclosed, wherein these instruments are provided with an MR-safe RF transmission line or cable (2, 3) for connecting the instrument with related RF transmit/MR receive units or other signal processing units for operating the instrument during an MR imaging or MR examination of an examination object. Basically, MR safety is obtained or increased by means of a plurality of fuses (6) which are serially connected into the transmission line or cable (2, 3).
摘要:
A transmission cable including a transmission line, at least two electrically conductive line segments separated by a non-conductive gap, a bridging unit including at least one electrically conductive bridge segment capable of bridging the non-conductive gap, and a switching unit arranged to move the bridging unit and/or the transmission line to electrically connect the two line segments by closing the non-conductive gap using the bridge segment or to electrically disconnect the two line segments by opening the non-conductive gap.
摘要:
A guide wire (400, 500, 600, 700, 800, 900, 1000, 1200, 1300) is adapted for use in magnetic resonance imaging systems. The guide wire has a shaft region (402) and a distal tip region (404). The shaft region comprises a composite shaft (406) comprising reinforcing fibers aligned with a length extension (403) of the shaft region. The fibers extend at least partially into the distal tip region. The fibers form a taper (410) within the distal tip region. The distal tip region comprises a sensor (504, 604, 702, 704, 804, 904, 1006, 1008). The shaft comprises a cable (502, 602, 702, 704, 802, 902, 1002, 1004). The cable is connected to the sensor.
摘要:
A medical apparatus (1100) comprising a magnetic resonance imaging system and an interventional device (300) comprising a shaft (302, 1014, 1120). The medical apparatus further comprises a toroidal magnetic resonance fiducial marker (306, 600, 800, 900, 1000, 1122) attached to the shaft. The shaft passes through a center point (610, 810, 908, 1006) of the fiducial marker. The medical apparatus further comprises machine executable instructions (1150, 1152, 1154, 1156, 1158) for execution by a processor. The instructions cause the processor to acquire (100, 200) magnetic resonance data, to reconstruct (102, 202) a magnetic resonance image (1142), and to receive (104, 204) the selection of a target volume (1118, 1144, 1168). The instructions further cause the processor to repeatedly: acquire (106, 206) magnetic resonance location data (1146) from the fiducial marker and render (108, 212) a view (1148, 1162) indicating the position of the shaft relative to the target zone.