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公开(公告)号：US09913982B2
公开(公告)日：2018-03-13
申请号：US13106460
申请日：2011-05-12
申请人： Stephen L. Bolea , Thomas B. Hoegh , Brian D. Kuhnley , Dale G. Suilmann , Bruce J. Persson , John P. Beck , Sidney F. Hauschild , Wondimeneh Tesfayesus , Jason J. Skubitz , Mark R. Bosshard , Daniel A. Parrish , Robert E. Atkinson
发明人： Stephen L. Bolea , Thomas B. Hoegh , Brian D. Kuhnley , Dale G. Suilmann , Bruce J. Persson , John P. Beck , Sidney F. Hauschild , Wondimeneh Tesfayesus , Jason J. Skubitz , Mark R. Bosshard , Daniel A. Parrish , Robert E. Atkinson
CPC分类号： A61N1/3601 , A61B5/0809 , A61B5/0826 , A61B5/4818 , A61N1/0556 , A61N1/3611 , A61N1/36132 , A61N1/36139 , A61N1/3615 , A61N1/37235
摘要： Devices, systems and methods of neurostimulation for treating obstructive sleep apnea. The system is adapted to send an electrical signal from an implanted neurostimulator through a stimulation lead to a patient's nerve at an appropriate phase of the respiratory cycle based on input from a respiration sensing lead. External components are adapted for wireless communication with the neurostimulator. The neurostimulator is adapted to deliver therapeutic stimulation based on inputs.
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公开(公告)号：US20120192874A1
公开(公告)日：2012-08-02
申请号：US13106460
申请日：2011-05-12
申请人： Stephen L. BOLEA , Thomas B. Hoegh , Brian D. Kuhnley , Dale G. Suilmann , Bruce J. Persson , John P. Beck , Sidney F. Hauschild , Wondimeneh Tesfayesus , Jason J. Skubitz , Mark R. Bosshard , Daniel A. Parrish , Robert E. Atkinson
发明人： Stephen L. BOLEA , Thomas B. Hoegh , Brian D. Kuhnley , Dale G. Suilmann , Bruce J. Persson , John P. Beck , Sidney F. Hauschild , Wondimeneh Tesfayesus , Jason J. Skubitz , Mark R. Bosshard , Daniel A. Parrish , Robert E. Atkinson
CPC分类号： A61N1/3601 , A61B5/0809 , A61B5/0826 , A61B5/4818 , A61N1/0556 , A61N1/3611 , A61N1/36132 , A61N1/36139 , A61N1/3615 , A61N1/37235
摘要： Devices, systems and methods of neurostimulation for treating obstructive sleep apnea. The system is adapted to send an electrical signal from an implanted neurostimulator through a stimulation lead to a patient's nerve at an appropriate phase of the respiratory cycle based on input from a respiration sensing lead. External components are adapted for wireless communication with the neurostimulator. The neurostimulator is adapted to deliver therapeutic stimulation based on inputs.
摘要翻译： 用于治疗阻塞性睡眠呼吸暂停的神经刺激的装置，系统和方法。 该系统适于基于来自呼吸感测引线的输入，将来自植入的神经刺激器的电信号通过刺激引线发送到呼吸周期的适当阶段到患者的神经。 外部组件适用于与神经刺激器的无线通信。 神经刺激器适于基于输入传递治疗刺激。
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公开(公告)号：US20100174341A1
公开(公告)日：2010-07-08
申请号：US12650045
申请日：2009-12-30
申请人： Stephen L. Bolea , Thomas B. Hoegh , Brian D. Kuhnley , Dale G. Suilmann , Bruce J. Persson , John P. Beck , Sidney F. Hauschild , Paula M. Kaplan , Adam K. Hoyhtya , Wondimeneh Tesfayesus , Robert E. Atkinson
发明人： Stephen L. Bolea , Thomas B. Hoegh , Brian D. Kuhnley , Dale G. Suilmann , Bruce J. Persson , John P. Beck , Sidney F. Hauschild , Paula M. Kaplan , Adam K. Hoyhtya , Wondimeneh Tesfayesus , Robert E. Atkinson
IPC分类号： A61N1/36
CPC分类号： A61N1/3601 , A61B5/0538 , A61B5/4818 , A61N1/0556 , A61N1/3611 , A61N1/36139
摘要： Devices, systems and methods of neurostimulation for treating obstructive sleep apnea.
摘要翻译： 用于治疗阻塞性睡眠呼吸暂停的神经刺激的装置，系统和方法。
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公开(公告)号：US20110160794A1
公开(公告)日：2011-06-30
申请号：US12980840
申请日：2010-12-29
申请人： Stephen L. Bolea , Thomas B. Hoegh , Brian D. Kuhnley , Dale G. Suilmann , Bruce J. Persson , John P. Beck , Sidney F. Hauschild , Paula M. Kaplan , Adam K. Hoyhtya , Wondimeneh Tesfayesus , Robert E. Atkinson
发明人： Stephen L. Bolea , Thomas B. Hoegh , Brian D. Kuhnley , Dale G. Suilmann , Bruce J. Persson , John P. Beck , Sidney F. Hauschild , Paula M. Kaplan , Adam K. Hoyhtya , Wondimeneh Tesfayesus , Robert E. Atkinson
IPC分类号： A61N1/36
CPC分类号： A61N1/3601 , A61B5/0538 , A61B5/4818 , A61N1/0556 , A61N1/3611 , A61N1/36139
摘要： Devices, systems and methods of neurostimulation for treating obstructive sleep apnea.
摘要翻译： 用于治疗阻塞性睡眠呼吸暂停的神经刺激的装置，系统和方法。
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公开(公告)号：US10105538B2
公开(公告)日：2018-10-23
申请号：US12980840
申请日：2010-12-29
申请人： Stephen L. Bolea , Thomas B. Hoegh , Brian D. Kuhnley , Dale G. Suilmann , Bruce J. Persson , John P. Beck , Sidney F. Hauschild , Paula M. Kaplan , Adam K. Hoyhtya , Wondimeneh Tesfayesus , Robert E. Atkinson
发明人： Stephen L. Bolea , Thomas B. Hoegh , Brian D. Kuhnley , Dale G. Suilmann , Bruce J. Persson , John P. Beck , Sidney F. Hauschild , Paula M. Kaplan , Adam K. Hoyhtya , Wondimeneh Tesfayesus , Robert E. Atkinson
摘要： Devices, systems and methods of neurostimulation for treating obstructive sleep apnea.
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公开(公告)号：US09744354B2
公开(公告)日：2017-08-29
申请号：US12650045
申请日：2009-12-30
申请人： Stephen L. Bolea , Thomas B. Hoegh , Brian D. Kuhnley , Dale G. Suilmann , Bruce J. Persson , John P. Beck , Sidney F. Hauschild , Paula M. Kaplan , Adam K. Hoyhtya , Wondimeneh Tesfayesus , Robert E. Atkinson , Peter R. Eastwood , David R. Hillman
发明人： Stephen L. Bolea , Thomas B. Hoegh , Brian D. Kuhnley , Dale G. Suilmann , Bruce J. Persson , John P. Beck , Sidney F. Hauschild , Paula M. Kaplan , Adam K. Hoyhtya , Wondimeneh Tesfayesus , Robert E. Atkinson , Peter R. Eastwood , David R. Hillman
CPC分类号： A61N1/3601 , A61B5/0538 , A61B5/4818 , A61N1/0556 , A61N1/3611 , A61N1/36139
摘要： Devices, systems and methods of neurostimulation for treating obstructive sleep apnea.
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公开(公告)号：US08417343B2
公开(公告)日：2013-04-09
申请号：US11907533
申请日：2007-10-12
申请人： Stephen L. Bolea , Thomas B. Hoegh , Bruce J. Persson , Robert E. Atkinson , Sidney F. Hauschild , Paula M. Kaplan , Brian D. Kuhnley , Keith E. Jasperson , Wondimeneh Tesfayesus , Christopher K. Thorp
发明人： Stephen L. Bolea , Thomas B. Hoegh , Bruce J. Persson , Robert E. Atkinson , Sidney F. Hauschild , Paula M. Kaplan , Brian D. Kuhnley , Keith E. Jasperson , Wondimeneh Tesfayesus , Christopher K. Thorp
IPC分类号： A61N1/36
CPC分类号： A61N1/3606 , A61B5/0809 , A61B5/4818 , A61B5/7239 , A61N1/0556 , A61N1/0558 , A61N1/3601 , A61N1/37229
摘要： Devices, systems and methods for nerve stimulation for OSA therapy.
摘要翻译： 用于OSA治疗的神经刺激的装置，系统和方法。
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公开(公告)号：US08428727B2
公开(公告)日：2013-04-23
申请号：US13093534
申请日：2011-04-25
申请人： Stephen L. Bolea , Thomas B. Hoegh , Bruce J. Persson , Robert E. Atkinson , Sidney F. Hauschild , Paula M. Kaplan , Brian D. Kuhnley , Keith E. Jasperson , Wondimeneh Tesfayesus , Christopher K. Thorp
发明人： Stephen L. Bolea , Thomas B. Hoegh , Bruce J. Persson , Robert E. Atkinson , Sidney F. Hauschild , Paula M. Kaplan , Brian D. Kuhnley , Keith E. Jasperson , Wondimeneh Tesfayesus , Christopher K. Thorp
IPC分类号： A61N1/36
CPC分类号： A61N1/3606 , A61B5/0809 , A61B5/4818 , A61B5/7239 , A61N1/0556 , A61N1/0558 , A61N1/3601 , A61N1/37229
摘要： In one embodiment, a method for maintaining patency of an upper airway of a patient to treat obstructive sleep apnea may include delivering an electrical stimulation to a portion of a superior laryngeal nerve via a nerve cuff when the nerve cuff is adjacent an external surface of the superior laryngeal nerve, the nerve cuff having a plurality of electrodes, wherein the nerve cuff is configured to be connected to an electrical stimulator via a stimulation lead.
摘要翻译： 在一个实施例中，用于维持患者的上呼吸道通畅以治疗阻塞性睡眠呼吸暂停的方法可以包括：当神经袖带邻近于外部表面时，通过神经袖带将电刺激递送至上喉神经的一部分 上喉神经，神经袖带具有多个电极，其中所述神经囊被构造成通过刺激引线连接到电刺激器。
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公开(公告)号：US20110202106A1
公开(公告)日：2011-08-18
申请号：US13093534
申请日：2011-04-25
申请人： Stephen L. Bolea , Thomas B. Hoegh , Bruce J. Persson , Robert E. Atkinson , Sidney F. Hauschild , Paula M. Kaplan , Brian D. Kuhnley , Keith E. Jasperson , Wondimeneh Tesfayesus , Christopher K. Thorp
发明人： Stephen L. Bolea , Thomas B. Hoegh , Bruce J. Persson , Robert E. Atkinson , Sidney F. Hauschild , Paula M. Kaplan , Brian D. Kuhnley , Keith E. Jasperson , Wondimeneh Tesfayesus , Christopher K. Thorp
CPC分类号： A61N1/3606 , A61B5/0809 , A61B5/4818 , A61B5/7239 , A61N1/0556 , A61N1/0558 , A61N1/3601 , A61N1/37229
摘要： Devices, systems and methods for nerve stimulation for OSA therapy.
摘要翻译： 用于OSA治疗的神经刺激的装置，系统和方法。
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公开(公告)号：US20140188185A1
公开(公告)日：2014-07-03
申请号：US13205315
申请日：2011-08-08
IPC分类号： A61N1/36
CPC分类号： A61B5/0826 , A61B1/233 , A61B1/267 , A61B5/4552 , A61N1/0519 , A61N1/0551 , A61N1/3601 , A61N1/3611 , A61N1/36139
摘要： Devices and methods for treating obstructive sleep apnea by first performing an assessment of the patient that involves observing the patient's upper airway during a tongue protrusion maneuver. The assessment may, for example, be done using endoscopy to observe the upper airway while the patient is awake in the supine position. An adequate response of the upper airway during the tongue protrusion maneuver is indicative of likely therapeutic success with hypoglossal nerve stimulation, and may be used for making clinical decisions. The principles of the present invention may be applied to other therapeutic interventions for OSA involving the upper airway.
摘要翻译： 通过首先对患者的评估进行治疗阻塞性睡眠呼吸暂停的装置和方法，其涉及在舌突出动作期间观察患者的上呼吸道。 例如，可以使用内窥镜检查来观察患者在仰卧位时醒来时观察上呼吸道的评估。 在舌突出动作期间上呼吸道的充分反应表明舌下神经刺激可能具有治疗成功的作用，并可用于进行临床决策。 本发明的原理可以应用于涉及上呼吸道的OSA的其它治疗干预。
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