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1.发明授权公开(公告)号：US08012763B2
公开(公告)日：2011-09-06
申请号：US12322158
申请日：2009-01-29
IPC分类号： G01N21/77
CPC分类号： G01N30/74 , B01L3/0275 , G01N1/40 , G01N1/4044 , G01N21/658 , G01N30/6082 , G01N30/78 , G01N2030/746 , G01N21/63
摘要： A stationary medium is employed both to separate chemicals from a sample solution and also to generate surface-enhanced Raman scattering, so that spectral analysis of the separated analyte chemical can be performed. Applied driving force causes the sample to flow into the stationary medium and to distribute therethrough, thereby causing rapid separation of the analyte chemical, and surface-enhanced Raman scattered radiation is quickly detected, at a plurality of locations along a flow path defined by the stationary medium, for ultimate analysis.
摘要翻译： 既采用固定介质将样品溶液中的化学物质分开，也可产生表面增强的拉曼散射，从而可以进行分离的分析物化学品的光谱分析。 施加的驱动力使得样品流入固定介质并分布在其中，从而导致分析物化学物质的快速分离，并且在沿着由静止物定义的流动路径的多个位置处快速检测到表面增强的拉曼散射辐射 中等，用于最终分析。
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2.发明授权Apparatus for effecting analysis with rapid analyte chemical separation and subsequent detection 有权用快速分析物化学分离和随后检测进行分析的装置公开(公告)号：US08932524B2
公开(公告)日：2015-01-13
申请号：US13199601
申请日：2011-09-02
CPC分类号： G01N21/658 , B01L3/5027 , G01N1/40 , G01N30/6082 , G01N30/6095 , G01N30/74 , G01N30/78 , G01N21/63
摘要： A stationary medium is employed both to separate chemicals from a sample solution and also to generate surface-enhanced Raman scattering, so that spectral analysis of the separated analyte chemical can be performed. Applied driving force causes the sample to flow into the stationary medium and to distribute therethrough, thereby causing rapid separation of the analyte chemical, and surface-enhanced Raman scattered radiation is quickly detected, at a plurality of locations along a flow path defined by the stationary medium, for ultimate analysis.
摘要翻译： 既采用固定介质将样品溶液中的化学物质分开，也可产生表面增强的拉曼散射，从而可以进行分离的分析物化学品的光谱分析。 施加的驱动力使得样品流入固定介质并分布在其中，从而导致分析物化学物质的快速分离，并且在沿着由静止物定义的流动路径的多个位置处快速检测到表面增强的拉曼散射辐射 中等，用于最终分析。
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3.发明申请Apparatus for effecting analysis with rapid analyte chemical separation and subsequent detection 审中-公开用快速分析物化学分离和随后检测进行分析的装置公开(公告)号：US20110317159A1
公开(公告)日：2011-12-29
申请号：US13199601
申请日：2011-09-02
IPC分类号： G01J3/44
CPC分类号： G01N21/658 , B01L3/5027 , G01N1/40 , G01N30/6082 , G01N30/6095 , G01N30/74 , G01N30/78 , G01N21/63
摘要： A stationary medium is employed both to separate chemicals from a sample solution and also to generate surface-enhanced Raman scattering, so that spectral analysis of the separated analyte chemical can be performed. Applied driving force causes the sample to flow into the stationary medium and to distribute therethrough, thereby causing rapid separation of the analyte chemical, and surface-enhanced Raman scattered radiation is quickly detected, at a plurality of locations along a flow path defined by the stationary medium, for ultimate analysis.
摘要翻译： 既采用固定介质将样品溶液中的化学物质分开，也可产生表面增强的拉曼散射，从而可以进行分离的分析物化学品的光谱分析。 施加的驱动力使得样品流入固定介质并分布在其中，从而导致分析物化学物质的快速分离，并且在沿着由静止物定义的流动路径的多个位置处快速检测到表面增强的拉曼散射辐射 中等，用于最终分析。
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4.发明申请公开(公告)号：US20090168059A1
公开(公告)日：2009-07-02
申请号：US12322158
申请日：2009-01-29
CPC分类号： G01N30/74 , B01L3/0275 , G01N1/40 , G01N1/4044 , G01N21/658 , G01N30/6082 , G01N30/78 , G01N2030/746 , G01N21/63
摘要： A stationary medium is employed both to separate chemicals from a sample solution and also to generate surface-enhanced Raman scattering, so that spectral analysis of the separated analyte chemical can be performed. Applied driving force causes the sample to flow into the stationary medium and to distribute therethrough, thereby causing rapid separation of the analyte chemical, and surface-enhanced Raman scattered radiation is quickly detected, at a plurality of locations along a flow path defined by the stationary medium, for ultimate analysis.
摘要翻译： 既采用固定介质将样品溶液中的化学物质分开，也可产生表面增强的拉曼散射，从而可以进行分离的分析物化学品的光谱分析。 施加的驱动力使得样品流入固定介质并分布在其中，从而导致分析物化学物质的快速分离，并且在沿着由静止物定义的流动路径的多个位置处快速检测到表面增强的拉曼散射辐射 中等，用于最终分析。
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5.发明授权公开(公告)号：US07393692B2
公开(公告)日：2008-07-01
申请号：US11098844
申请日：2005-04-05
CPC分类号： G01N21/658 , Y10T436/141111 , Y10T436/147777 , Y10T436/163333 , Y10T436/25375 , Y10T436/255
摘要： The method and apparatus rapidly separate drugs and their metabolites from saliva and, in a continuous sequence of steps, rapidly detect, identify and quantify them through surface-enhanced Raman spectroscopy.
摘要翻译： 该方法和装置将药物及其代谢物从唾液中快速分离，并以连续的步骤顺序通过表面增强拉曼光谱快速检测，鉴定和定量。
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6.发明授权SERS method and apparatus for rapid extraction and analysis of drugs in saliva 有权SERS方法和仪器，用于唾液中药物的快速提取和分析公开(公告)号：US07393691B2
公开(公告)日：2008-07-01
申请号：US10967486
申请日：2004-10-18
CPC分类号： G01N21/658 , Y10T436/141111 , Y10T436/147777 , Y10T436/163333 , Y10T436/25375 , Y10T436/255
摘要： The method and apparatus rapidly separate drugs and their metabolites from saliva and, in a continuous sequence of steps, rapidly detect, identify and quantify them through surface-enhanced Raman spectroscopy.
摘要翻译： 该方法和装置将药物及其代谢物从唾液中快速分离，并以连续的步骤顺序通过表面增强拉曼光谱快速检测，鉴定和定量。
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7.发明申请Apparatus for effecting chemical separation and plural-point sers detection using metal-doped sol-gels 失效使用金属掺杂溶胶进行化学分离和多点检测的装置公开(公告)号：US20050282287A1
公开(公告)日：2005-12-22
申请号：US11193894
申请日：2005-07-29
申请人： Stuart Farquharson , Paul Maksymiuk
发明人： Stuart Farquharson , Paul Maksymiuk
CPC分类号： G01N21/658 , B01L3/0275 , B01L3/5023 , B01L2300/0816 , B01L2300/0838 , B01L2300/087 , B01L2400/0457 , G01N1/40 , G01N30/6082 , G01N30/74 , G01N30/78 , G01N21/63
摘要： Sol-gel beds and deposits are utilized for SERS analysis of liquid analytes. Measurements are made at multiple points along the length of a column or channel to increase, very significantly, the speed of analysis, and use of the same medium to both separate the chemicals and also for SERS greatly reduces the complexity of such apparatus and enhances the efficiency of the method.
摘要翻译： 溶胶凝胶床和沉积物用于液体分析物的SERS分析。 在柱或通道的长度上的多个点进行测量，以非常显着地增加分析速度，并且使用相同的介质来分离化学品并且还用于SERS，大大降低了这种装置的复杂性并且增强了 方法的效率。
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8.发明授权Apparatus for effecting chemical separation and plural-point SERS detection using metal-doped sol-gels 失效用金属掺杂溶胶凝胶进行化学分离和多点SERS检测的装置公开(公告)号：US07462492B2
公开(公告)日：2008-12-09
申请号：US11193894
申请日：2005-07-29
申请人： Stuart Farquharson , Paul Maksymiuk
发明人： Stuart Farquharson , Paul Maksymiuk
IPC分类号： G01N21/76
CPC分类号： G01N21/658 , B01L3/0275 , B01L3/5023 , B01L2300/0816 , B01L2300/0838 , B01L2300/087 , B01L2400/0457 , G01N1/40 , G01N30/6082 , G01N30/74 , G01N30/78 , G01N21/63
摘要： Sol-gel beds and deposits are utilized for SERS analysis of liquid analytes. Measurements are made at multiple points along the length of a column or channel to increase, very significantly, the speed of analysis, and use of the same medium to both separate the chemicals and also for SERS greatly reduces the complexity of such apparatus and enhances the efficiency of the method.
摘要翻译： 溶胶凝胶床和沉积物用于液体分析物的SERS分析。 在柱或通道的长度上的多个点进行测量，以非常显着地增加分析速度，并且使用相同的介质来分离化学品并且还用于SERS，大大降低了这种装置的复杂性并且增强了 方法的效率。
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9.发明授权Apparatus for effecting chemical separation and SERS detection using metal-doped sol-gels 有权使用金属掺杂溶胶进行化学分离和SERS检测的装置公开(公告)号：US07462493B2
公开(公告)日：2008-12-09
申请号：US11193895
申请日：2005-07-29
申请人： Stuart Farquharson , Paul Maksymiuk
发明人： Stuart Farquharson , Paul Maksymiuk
IPC分类号： G01N21/76
CPC分类号： G01N21/658 , B01J20/02 , B01J20/28047 , B01J20/286 , B01J20/291 , B01J2220/54 , B01L3/0275 , B01L3/5023 , B01L2300/0816 , B01L2300/0838 , B01L2300/087 , B01L2400/0457 , G01N1/40 , G01N30/6082 , G01N30/74 , G01N21/63
摘要： Sol-gel beds and deposits are utilized for SERS analysis of liquid analytes. The use of the same medium to both separate the chemicals and also for SERS greatly reduces the complexity of such apparatus and enhances the efficiency of the method.
摘要翻译： 溶胶凝胶床和沉积物用于液体分析物的SERS分析。 使用相同的介质来分离化学品，也为SERS分离，大大降低了这种设备的复杂性，并提高了该方法的效率。
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10.发明授权Chemical separation and plural-point, surface-enhanced raman spectral detection using metal-doped sol-gels 有权使用金属掺杂溶胶的化学分离和多点，表面增强拉曼光谱检测公开(公告)号：US06943032B2
公开(公告)日：2005-09-13
申请号：US10372622
申请日：2003-02-21
申请人： Stuart Farquharson , Paul Maksymiuk
发明人： Stuart Farquharson , Paul Maksymiuk
CPC分类号： G01N21/658 , B01L3/0275 , B01L3/5023 , B01L2300/0816 , B01L2300/0838 , B01L2300/087 , B01L2400/0457 , G01N1/40 , G01N30/6082 , G01N30/74 , G01N30/78 , G01N21/63
摘要： Sol-gel beds and deposits are utilized for SERS analysis of liquid analytes. Measurements are made at multiple points along the length of a column or channel to increase, very significantly, the speed of analysis, and use of the same medium to both separate the chemicals and also for SERS greatly reduces the complexity of such apparatus and enhances the efficiency of the method.
摘要翻译： 溶胶凝胶床和沉积物用于液体分析物的SERS分析。 在柱或通道的长度上的多个点进行测量，以非常显着地增加分析速度，并且使用相同的介质来分离化学品并且还用于SERS，大大降低了这种装置的复杂性并且增强了 方法的效率。
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