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公开(公告)号：US20110301447A1
公开(公告)日：2011-12-08
申请号：US13134507
申请日：2011-06-07
申请人： Sun Young Park , Dustin Sargent , Ulf Peter Gustafsson , Wenjing Li , Rolf Wolters , Stephen D. Fleischer
发明人： Sun Young Park , Dustin Sargent , Ulf Peter Gustafsson , Wenjing Li , Rolf Wolters , Stephen D. Fleischer
CPC分类号： G06T7/0016 , G06T2207/10016 , G06T2207/10068 , G06T2207/20076 , G06T2207/20081 , G06T2207/30032
摘要： A process and device for detecting colon cancer by classifying and annotating clinical features in video data containing colonoscopic features by applying a probabilistic analysis to intra-frame and inter-frame relationships between colonoscopic features in spatially and temporally neighboring portions of video frames, and classifying and annotating as clinical features any of the colonoscopic features that satisfy the probabilistic analysis as clinical features. Preferably the probabilistic analysis is Hidden Markove Model analysis, and the process is carried out by a computer trained using semi supervised learning from labeled and unlabeled examples of clinical features in video containing colonoscopic features.
摘要翻译： 通过对视频帧的空间和时间相邻部分中的结肠镜检查特征之间的帧内和帧间关系进行概率分析，对包含结肠镜特征的视频数据中的临床特征进行分类和注释来检测结肠癌的过程和装置，以及分类和 注释为临床特征任何结肠镜检查特征，满足作为临床特征的概率分析。 优选地，概率分析是隐藏的Markove模型分析，并且该过程由使用半监督学习的计算机进行，该计算机通过标签和未标记的包含结肠镜特征的视频的临床特征实例来实施。
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2.发明申请Methods for detection and characterization of atypical vessels in cervical imagery 失效宫颈图像中非典型血管的检测和表征方法公开(公告)号：US20100027863A1
公开(公告)日：2010-02-04
申请号：US12221328
申请日：2008-08-01
IPC分类号： A61B5/00
CPC分类号： A61B5/02007 , A61B1/00009 , A61B5/0084 , G06T7/0012 , G06T7/11 , G06T2207/30096 , G06T2207/30101
摘要： The present invention discloses a method for the detection of atypical vessels in digital cervical imagery. A pre-processing stage is applied to enhance the contrast of blood vessel features compared to the surrounding tissue. Next, a segmentation stage is applied to identify regions of interest for atypical vessels using texture and gradient information. Finally, a post-processing stage (1) identifies other clinically relevant features in the cervical imager, and removes these features from the region of interest; and (2) uses color, size, and shape information to further refine the region of interest to eliminate false positives and determine a final region of interest. This automated method of atypical vessel detection is especially useful for diagnostic purposes such as cervical cancer detection.
摘要翻译： 本发明公开了一种检测数字宫颈图像中非典型血管的方法。 应用预处理阶段来增强与周围组织相比的血管特征的对比度。 接下来，使用分割阶段来使用纹理和梯度信息来识别非典型血管的感兴趣区域。 最后，后处理阶段（1）识别子宫颈成像仪中的其他临床相关特征，并从感兴趣区域中去除这些特征; 和（2）使用颜色，大小和形状信息进一步细化感兴趣的区域以消除假阳性，并确定最终感兴趣的区域。 这种非典型血管检测的自动化方法对于诸如宫颈癌检测的诊断目的尤其有用。
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3.发明授权Methods for detection and characterization of atypical vessels in cervical imagery 失效宫颈图像中非典型血管的检测和表征方法公开(公告)号：US08090177B2
公开(公告)日：2012-01-03
申请号：US12221328
申请日：2008-08-01
IPC分类号： G06K9/00
CPC分类号： A61B5/02007 , A61B1/00009 , A61B5/0084 , G06T7/0012 , G06T7/11 , G06T2207/30096 , G06T2207/30101
摘要： The present invention discloses a method for the detection of atypical vessels in digital cervical imagery. A pre-processing stage is applied to enhance the contrast of blood vessel features compared to the surrounding tissue. Next, a segmentation stage is applied to identify regions of interest for atypical vessels using texture and gradient information. Finally, a post-processing stage (1) identifies other clinically relevant features in the cervical imager, and removes these features from the region of interest; and (2) uses color, size, and shape information to further refine the region of interest to eliminate false positives and determine a final region of interest. This automated method of atypical vessel detection is especially useful for diagnostic purposes such as cervical cancer detection.
摘要翻译： 本发明公开了一种检测数字宫颈图像中非典型血管的方法。 应用预处理阶段来增强与周围组织相比的血管特征的对比度。 接下来，使用分割阶段来使用纹理和梯度信息来识别非典型血管的感兴趣区域。 最后，后处理阶段（1）识别子宫颈成像仪中的其他临床相关特征，并从感兴趣区域中去除这些特征; 和（2）使用颜色，大小和形状信息进一步细化感兴趣的区域以消除假阳性，并确定最终感兴趣的区域。 这种非典型血管检测的自动化方法对于诸如宫颈癌检测的诊断目的尤其有用。
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4.发明申请Computerized image analysis for acetic acid induced Cervical Intraepithelial Neoplasia 失效乙酸诱导宫颈上皮内瘤变的电脑图像分析公开(公告)号：US20090034824A1
公开(公告)日：2009-02-05
申请号：US12221645
申请日：2008-08-04
申请人： Wenjing Li , Rolf Holger Wolters
发明人： Wenjing Li , Rolf Holger Wolters
IPC分类号： G06K9/00
CPC分类号： G06K9/4652 , G06T7/0012 , G06T7/11 , G06T7/174 , G06T2207/10024 , G06T2207/20041 , G06T2207/30096
摘要： A method for differentiating cancerous lesions from surrounding tissue, which includes extracting an opacity parameter from acetowhite regions of pre acetic acid and post acetic acid images of a cervix.
摘要翻译： 一种用于将癌变病变与周围组织分离的方法，其包括从乙酸的乙酸钠区域和子宫颈的后乙酸图像中提取不透明度参数。
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5.发明申请公开(公告)号：US20080226148A1
公开(公告)日：2008-09-18
申请号：US12075910
申请日：2008-03-14
申请人： Jia Gu , Wenjing Li , John Hargrove , Rolf Holger Wolters
发明人： Jia Gu , Wenjing Li , John Hargrove , Rolf Holger Wolters
CPC分类号： G06T5/40 , A61B5/0084 , G06K9/4652 , G06T5/007 , G06T5/50 , G06T7/0002 , G06T2207/10016 , G06T2207/10024 , G06T2207/10152 , G06T2207/30004 , G06T2207/30168
摘要： Automated image quality assessment methods, which include locating a region of interest, region assessment, contrast assessment, blur assessment, and contaminant detection, on video data and high-resolution imagery. Where the blur assessment is performed without a reference image by dividing the region into non-overlapping block, measuring the wavenumber frequency of the blocks and calculating the ratio of the low frequency to high frequency areas.
摘要翻译： 自动图像质量评估方法，包括定位感兴趣区域，区域评估，对比度评估，模糊评估和污染物检测，对视频数据和高分辨率图像。 在通过将区域划分为非重叠块来进行模糊评估而不参考图像的情况下，测量块的波数频率并计算低频到高频区域的比率。
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公开(公告)号：US08622548B2
公开(公告)日：2014-01-07
申请号：US13299219
申请日：2011-11-17
申请人： Cheng-en Guo , Ben Jang , Wenjing Li
发明人： Cheng-en Guo , Ben Jang , Wenjing Li
CPC分类号： A61B3/102 , G06T7/11 , G06T7/187 , G06T2207/10101 , G06T2207/20156
摘要： System and method for 3D retinal disruption/elevation detection, measurement and presentation using Optical Coherence Tomography (OCT) are provided. The present invention is capable of detecting and measuring the abnormal changes of retinal layers (retinal disruptions), caused by retinal diseases, such as hard drusen, soft drusen, Pigment Epithelium Detachment (PED), Choroidal Neovascularization (CNV), Geographic Atrophy (GA), intra retinal fluid space, and exudates etc. The presentations of the results are provided with quantitative measurements of disruptions in retina and can be used for diagnosis and treatment of retinal diseases.
摘要翻译： 提供了使用光学相干断层扫描（OCT）的3D视网膜中断/仰角检测，测量和呈现的系统和方法。 本发明能够检测和测量视网膜疾病引起的视网膜层异常变化（视网膜中断），如硬玻璃疣，软玻璃疣，色素上皮分离（PED），脉络膜新血管形成（CNV），地理萎缩（GA） ），视网膜内液体空间和渗出液等。结果的呈现提供了视网膜中断的定量测量，可用于视网膜疾病的诊断和治疗。
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7.发明授权Method to provide automated quality feedback to imaging devices to achieve standardized imaging data 失效为成像设备提供自动质量反馈以实现标准化成像数据的方法公开(公告)号：US08401258B2
公开(公告)日：2013-03-19
申请号：US12075890
申请日：2008-03-14
申请人： John Hargrove , Jia Gu , Wenjing Li , Rolf Holger Wolters
发明人： John Hargrove , Jia Gu , Wenjing Li , Rolf Holger Wolters
CPC分类号： G06T5/40 , A61B5/0084 , G06K9/4652 , G06T5/007 , G06T5/50 , G06T7/0002 , G06T2207/10016 , G06T2207/10024 , G06T2207/10152 , G06T2207/30004 , G06T2207/30168
摘要： Automated image quality assessment algorithms, which perform the functions of locating a region of interest, maximizing the image contrast, and ensuring the region of interest is properly centered in the image. Wherein the region of interest is located by spectral matching filter using a target spectrum obtained from samples of the image itself.
摘要翻译： 自动图像质量评估算法，其执行定位感兴趣区域的功能，最大化图像对比度，并确保感兴趣的区域在图像中适当地居中。 其中通过使用从图像本身的样本获得的目标光谱的光谱匹配滤波器来定位感兴趣区域。
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公开(公告)号：US08027533B2
公开(公告)日：2011-09-27
申请号：US12077659
申请日：2008-03-19
IPC分类号： G06K9/00
CPC分类号： H04N1/6033 , H04N1/00045 , H04N1/401 , H04N1/6086
摘要： A method of automated image calibration that corrects for non-uniform illumination and calibrates color that is simple, fast, automated, accurate and reliable. A gray balance algorithm is applied to correct for non-uniform illumination and a color calibration algorithm is then applied to calibrate the human subject data. The system has been applied in multiple clinical sites with different instruments.
摘要翻译： 一种自动图像校准方法，用于校正不均匀照明并校准简单，快速，自动，准确和可靠的颜色。 应用灰度平衡算法来校正不均匀照明，然后应用颜色校准算法来校准人类受试者数据。 该系统已应用于具有不同仪器的多个临床部位。
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公开(公告)号：US20100040263A1
公开(公告)日：2010-02-18
申请号：US12228739
申请日：2008-08-15
IPC分类号： A61B5/00
CPC分类号： G06T5/30 , G06T5/009 , G06T2207/30004 , G06T2207/30068
摘要： A method of contrast enhancement for improved visualization of diagnostically important tissue structures, such as blood vessels. A texture analysis algorithm is applied to identify regions with a high likelihood of disease. Mathematical morphology operations are applied to identify areas of high and low brightness (intensity). The low intensity areas are then subtracted, and controllably variable amounts of the high intensity areas are added, controlled by a selectable tuning parameter, to produce an image with controllably variable visualization enhancement.
摘要翻译： 一种对比度增强的方法，用于改善诊断上重要的组织结构如血管的可视化。 应用纹理分析算法识别疾病可能性高的地区。 应用数学形态学操作来识别高亮度和低亮度（强度）的区域。 然后减去低强度区域，并且通过可选择的调谐参数来控制可变量的高强度区域，以产生具有可控地可变的可视化增强的图像。
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公开(公告)号：US20070027412A1
公开(公告)日：2007-02-01
申请号：US11460442
申请日：2006-07-27
申请人： Wenjing Li , Stephen Chung , Roman Ferber
发明人： Wenjing Li , Stephen Chung , Roman Ferber
IPC分类号： A61H7/00
CPC分类号： A61H2201/0138 , A61H2201/0149 , A61H2201/1669 , A61H2203/0431 , A61H2205/081
摘要： A massage apparatus is disclosed with a housing and a motor oriented in the housing. An eccentric drive is driven by the motor for oscillating an elongate massage member. In one embodiment a pair of elongate massage members are provided. In another embodiment, a massage formation is limited to a range of linear translation in a first direction and limited to a range of rotational translation relative to the housing.
摘要翻译： 公开了具有壳体和定位在壳体中的电动机的按摩装置。 偏心驱动器由马达驱动，用于摆动细长的按摩部件。 在一个实施例中，提供了一对细长的按摩部件。 在另一个实施例中，按摩结构限于在第一方向上的线性平移范围，并且限制在相对于外壳的旋转平移的范围内。
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