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公开(公告)号：US20060018801A1
公开(公告)日：2006-01-26
申请号：US11188000
申请日：2005-07-25
申请人： Tae-sik Park , Sung-hee Lee , Jung-ho Kang , Young-il Kim , Moon-chul Lee
发明人： Tae-sik Park , Sung-hee Lee , Jung-ho Kang , Young-il Kim , Moon-chul Lee
IPC分类号： B01L3/00
CPC分类号： B01L3/50273 , B01L3/502715 , B01L2200/10 , B01L2300/049 , B01L2400/049 , B01L2400/06
摘要： A bio sample processing apparatus and method using vacuum chambers in which a bio sample is injected into a first vacuum chamber connected with one end of a bio processor and, after processing, is ejected into a second vacuum chamber connected with the other end of the bio processor. The vacuum chambers and bio processor are connected with each other to form an environment with a pressure lower than atmospheric pressure, and the bio sample moves toward the second vacuum chamber due to the pressure difference created by the injection of the bio sample into the first vacuum chamber.
摘要翻译： 一种使用真空室的生物样品处理装置和方法，其中将生物样品注入与生物处理器的一端连接的第一真空室中，并且在处理之后被喷射到与生物的另一端连接的第二真空室中 处理器。 真空室和生物处理器彼此连接以形成压力低于大气压的环境，并且生物样品由于将生物样品注入第一真空产生的压差而向第二真空室移动 房间。
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公开(公告)号：US20060073502A1
公开(公告)日：2006-04-06
申请号：US11225507
申请日：2005-09-13
申请人： Sung-hee Lee , Jung-ho Kang , Young-il Kim , Moon-chul Lee , Tae-sik Park
发明人： Sung-hee Lee , Jung-ho Kang , Young-il Kim , Moon-chul Lee , Tae-sik Park
CPC分类号： G01N33/5438 , G01N33/553
摘要： An apparatus and method for detecting a bio-bonding includes monitoring of a change of an electrical property before and after bio-bonding. The apparatus includes a signal transducer section having a substrate, a metallic thin film stepped on a surface of a certain region of the substrate, probe biomolecules formed on the metallic thin film, an input port connected with one side of the signal transducer section and into which a signal for monitoring an electrical property of the signal transducer section is input and a detector section for characteristic quantity connected with the other side of the signal transducer section so as to monitor an electrical property of the signal transducer section. The probe biomolecules are immobilized on the metallic thin film. The bio-bonding is detected through monitoring the electrical property of the signal transducer section before and after the bio-bonding.
摘要翻译： 用于检测生物粘合的装置和方法包括监测生物粘合之前和之后的电特性的变化。 该装置包括：信号传感器部，具有基板，在基板的特定区域的台阶上阶梯状的金属薄膜，形成在金属薄膜上的探针生物分子，与信号换能器部的一侧连接的输入口， 输入用于监视信号换能器部分的电气性能的信号，以及用于与信号换能器部分的另一侧连接的特征量的检测器部分，以监测信号换能器部分的电气特性。 探针生物分子固定在金属薄膜上。 通过在生物粘合之前和之后监测信号传感器部分的电性能来检测生物粘合。
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3.发明授权Bio-molecules detecting apparatus using electromagnetic induction and detecting method using the same 有权使用电磁感应的生物分子检测装置及使用其的检测方法公开(公告)号：US07785864B2
公开(公告)日：2010-08-31
申请号：US11184894
申请日：2005-07-20
申请人： Jung-ho Kang , Sung-hee Lee , Young-il Kim , Moon-chul Lee , Tae-sik Park
发明人： Jung-ho Kang , Sung-hee Lee , Young-il Kim , Moon-chul Lee , Tae-sik Park
CPC分类号： G01N27/3276 , G01N29/036
摘要： Provided are a bio-molecules detecting apparatus using electromagnetic induction and a detecting method using the same. An exemplary apparatus includes: a cantilever of which one end is fixed and the other end is set up to be movable; a first metal formed on a plane of the cantilever and receiving a signal; a bio chip formed in the first metal and having probe biomolecules for searching particular information on a sample to be analyzed; an electromagnetic inductor configured to form a magnetic field; a signal source for applying the signal to the first metal; and a detector for measuring signal values of the first metal before and after the biomolecule is coupled with the sample. The apparatus detects the bio-couple by converting a change in mechanical properties before and after the bio-coupling based on electromagnetic induction to detect a bio-couple.
摘要翻译： 提供了使用电磁感应的生物分子检测装置和使用其的检测方法。 一种示例性装置包括：其一端被固定并且另一端被设置为可移动的悬臂; 形成在悬臂的平面上并接收信号的第一金属; 在第一金属中形成的生物芯片，并具有用于搜索待分析样品的特定信息的探针生物分子; 构造成形成磁场的电磁感应器; 用于将信号施加到第一金属的信号源; 以及用于测量生物分子之前和之后第一金属的信号值与检测器结合的检测器。 该装置通过基于电磁感应转换生物耦合之前和之后的机械特性的变化来检测生物耦合，以检测生物耦合。
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4.发明申请Bio-molecules detecting apparatus using electromagnetic induction and detecting method using the same 有权使用电磁感应的生物分子检测装置及使用其的检测方法公开(公告)号：US20060019299A1
公开(公告)日：2006-01-26
申请号：US11184894
申请日：2005-07-20
申请人： Jung-ho Kang , Sung-hee Lee , Young-il Kim , Moon-chul Lee , Tae-sik Park
发明人： Jung-ho Kang , Sung-hee Lee , Young-il Kim , Moon-chul Lee , Tae-sik Park
CPC分类号： G01N27/3276 , G01N29/036
摘要： Provided are a bio-molecules detecting apparatus using electromagnetic induction and a detecting method using the same. An exemplary apparatus includes: a cantilever of which one end is fixed and the other end is set up to be movable; a first metal formed on a plane of the cantilever and receiving a signal; a bio chip formed in the first metal and having probe biomolecules for searching particular information on a sample to be analyzed; an electromagnetic inductor configured to form a magnetic field; a signal source for applying the signal to the first metal; and a detector for measuring signal values of the first metal before and after the biomolecule is coupled with the sample. The apparatus detects the bio-couple by converting a change in mechanical properties before and after the bio-coupling based on electromagnetic induction to detect a bio-couple.
摘要翻译： 提供了使用电磁感应的生物分子检测装置和使用其的检测方法。 一种示例性装置包括：其一端被固定并且另一端被设置为可移动的悬臂; 形成在悬臂的平面上并接收信号的第一金属; 在第一金属中形成的生物芯片，并具有用于搜索待分析样品的特定信息的探针生物分子; 构造成形成磁场的电磁感应器; 用于将信号施加到第一金属的信号源; 以及用于测量生物分子之前和之后第一金属的信号值与检测器结合的检测器。 该装置通过基于电磁感应转换生物耦合之前和之后的机械特性的变化来检测生物耦合，以检测生物耦合。
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公开(公告)号：US07795011B2
公开(公告)日：2010-09-14
申请号：US11188000
申请日：2005-07-25
申请人： Tae-sik Park , Sung-hee Lee , Jung-ho Kang , Young-il Kim , Moon-chul Lee
发明人： Tae-sik Park , Sung-hee Lee , Jung-ho Kang , Young-il Kim , Moon-chul Lee
CPC分类号： B01L3/50273 , B01L3/502715 , B01L2200/10 , B01L2300/049 , B01L2400/049 , B01L2400/06
摘要： A bio sample processing apparatus and method using vacuum chambers in which a bio sample is injected into a first vacuum chamber connected with one end of a bio processor and, after processing, is ejected into a second vacuum chamber connected with the other end of the bio processor. The vacuum chambers and bio processor are connected with each other to form an environment with a pressure lower than atmospheric pressure, and the bio sample moves toward the second vacuum chamber due to the pressure difference created by the injection of the bio sample into the first vacuum chamber.
摘要翻译： 一种使用真空室的生物样品处理装置和方法，其中将生物样品注入与生物处理器的一端连接的第一真空室中，并且在处理之后被喷射到与生物的另一端连接的第二真空室中 处理器。 真空室和生物处理器彼此连接以形成压力低于大气压的环境，并且生物样品由于将生物样品注入第一真空产生的压差而向第二真空室移动 房间。
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6.发明申请公开(公告)号：US20050266472A1
公开(公告)日：2005-12-01
申请号：US11139571
申请日：2005-05-31
申请人： Tae-sik Park , Sung-hee Lee , Jung-ho Kang , Young-il Kim , Moon-chul Lee , Jong-hwa Won
发明人： Tae-sik Park , Sung-hee Lee , Jung-ho Kang , Young-il Kim , Moon-chul Lee , Jong-hwa Won
IPC分类号： G01N22/00 , C12M1/00 , C12N15/09 , C12Q1/68 , G01N27/00 , G01N27/02 , G01N27/22 , G01N33/487 , G01N37/00 , C12M1/34 , H01F21/02
CPC分类号： G01N27/3276
摘要： An apparatus and method for detecting bio molecule using an inductor element that can detect the bonding reaction between a sample and a biochip by measuring the change of the electrical characteristics of a circuit including the inductance device. The method includes forming a signal conversion unit with at least one inductance device, arranging a biochip in a specified area of the signal conversion unit by immobilizing capturing probe biomolecules on a substrate and measuring electric characteristics of the signal conversion unit, performing a bonding reaction between a sample (such as DNA, RNA, protein, biomolecules, etc.) to be analyzed and the biochip, and measuring the electrical characteristics of the signal conversion unit after the reaction bonding. The result of the bio molecule detection is obtained through an electrical signal, and thus the capability of detecting the bio bonding reaction can be improved in comparison to the conventional apparatus and method.
摘要翻译： 一种使用电感器元件检测生物分子的装置和方法，该电感元件可以通过测量包括电感器件的电路的电特性的变化来检测样品和生物芯片之间的结合反应。 该方法包括：形成具有至少一个电感器件的信号转换单元，通过将捕获探针生物分子固定在基片上并测量信号转换单元的电特性，将生物芯片布置在信号转换单元的指定区域中， 待分析的样品（例如DNA，RNA，蛋白质，生物分子等）和生物芯片，以及测量反应结合后的信号转换单元的电特性。 通过电信号获得生物分子检测的结果，与以往的装置和方法相比，能够提高检测生物结合反应的能力。
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公开(公告)号：US20110020140A1
公开(公告)日：2011-01-27
申请号：US11266903
申请日：2005-11-04
申请人： Tae-sik Park , Young-il Kim , Jung-ho Kang , Moon-chul Lee
发明人： Tae-sik Park , Young-il Kim , Jung-ho Kang , Moon-chul Lee
IPC分类号： F04B37/02
CPC分类号： F04B19/006 , F04B43/043
摘要： Provided is a micro pump having a simple structure. The micro pump includes a pump chamber including inflow and outflow passages through which a drive fluid flows, a first valve configured to open or close the inflow passage, a second valve configured to open or close the outflow passage, and a pump chamber heating and cooling unit configured to heat or cool the pump chamber.
摘要翻译： 提供一种结构简单的微型泵。 微型泵包括泵室，其包括驱动流体流过的流入和流出通道，构造成打开或关闭流入通道的第一阀，构造成打开或关闭流出通道的第二阀，以及泵室加热和冷却 单元被配置为加热或冷却泵室。
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公开(公告)号：US20050239120A1
公开(公告)日：2005-10-27
申请号：US11114070
申请日：2005-04-26
申请人： Tae-sik Park , Jung-ho Kang , Jong-hwa Won , Young-il Kim , Moon-chul Lee
发明人： Tae-sik Park , Jung-ho Kang , Jong-hwa Won , Young-il Kim , Moon-chul Lee
IPC分类号： G01N22/00 , C12M1/00 , C12M1/34 , C12N15/09 , C12Q1/68 , G01N27/02 , G01N27/22 , G01N27/327 , G01N33/543 , G01R33/00
CPC分类号： G01N27/3275 , G01N33/48792
摘要： An apparatus and method of detecting bio molecular by measuring a variation of an electrical characteristic of a circuit having an inductance device and a capacitance device. The bio molecular detection method comprises providing a signal converting unit having at least one inductance device and at least one capacitance device connected with each other, disposing a biochip, which has capturing probe biomolecules attached to a substrate, at a location in the signal converting unit, and measuring an electrical characteristic of the signal converting unit, performing a coupling reaction of the biochip and a sample to be analyzed; and measuring an electrical characteristic of the signal converting unit after the coupling reaction.
摘要翻译： 通过测量具有电感器件和电容器件的电路的电特性的变化来检测生物分子的装置和方法。 所述生物分子检测方法包括提供信号转换单元，所述信号转换单元具有至少一个电感器件和至少一个电容器件，所述至少一个电容器件彼此连接，在所述信号转换单元中的位置处设置生物芯片，所述生物芯片具有连接到衬底的捕获探针生物分子 测量信号转换单元的电特性，进行生物芯片与待分析样品的偶联反应; 并测量耦合反应后的信号转换单元的电特性。
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公开(公告)号：US07896621B2
公开(公告)日：2011-03-01
申请号：US11266903
申请日：2005-11-04
申请人： Tae-sik Park , Young-il Kim , Jung-ho Kang , Moon-chul Lee
发明人： Tae-sik Park , Young-il Kim , Jung-ho Kang , Moon-chul Lee
IPC分类号： F04B19/24
CPC分类号： F04B19/006 , F04B43/043
摘要： Provided is a micro pump having a simple structure. The micro pump includes a pump chamber including inflow and outflow passages through which a drive fluid flows, a first valve configured to open or close the inflow passage, a second valve configured to open or close the outflow passage, and a pump chamber heating and cooling unit configured to heat or cool the pump chamber.
摘要翻译： 提供一种结构简单的微型泵。 微型泵包括泵室，其包括驱动流体流过的流入和流出通道，构造成打开或关闭流入通道的第一阀，构造成打开或关闭流出通道的第二阀，以及泵室加热和冷却 单元被配置为加热或冷却泵室。
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公开(公告)号：US07764070B2
公开(公告)日：2010-07-27
申请号：US11114070
申请日：2005-04-26
申请人： Tae-sik Park , Jung-ho Kang , Jong-hwa Won , Young-il Kim , Moon-chul Lee
发明人： Tae-sik Park , Jung-ho Kang , Jong-hwa Won , Young-il Kim , Moon-chul Lee
CPC分类号： G01N27/3275 , G01N33/48792
摘要： An apparatus and method of detecting bio molecular by measuring a variation of an electrical characteristic of a circuit having an inductance device and a capacitance device. The bio molecular detection method comprises providing a signal converting unit having at least one inductance device and at least one capacitance device connected with each other, disposing a biochip, which has capturing probe biomolecules attached to a substrate, at a location in the signal converting unit, and measuring an electrical characteristic of the signal converting unit, performing a coupling reaction of the biochip and a sample to be analyzed; and measuring an electrical characteristic of the signal converting unit after the coupling reaction.
摘要翻译： 通过测量具有电感器件和电容器件的电路的电特性的变化来检测生物分子的装置和方法。 所述生物分子检测方法包括提供信号转换单元，所述信号转换单元具有至少一个电感器件和至少一个电容器件，所述至少一个电容器件彼此连接，在所述信号转换单元中的位置处设置生物芯片，所述生物芯片具有连接到衬底的捕获探针生物分子 测量信号转换单元的电特性，进行生物芯片与待分析样品的偶联反应; 并测量耦合反应后的信号转换单元的电特性。
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