-
公开(公告)号：US07989189B2
公开(公告)日：2011-08-02
申请号：US11631542
申请日：2005-07-07
CPC分类号： C12N9/78
摘要： The present invention relates to modified GTP cyclohydrolase II enzymes that display increased specific activity, and to polynucleotides encoding them. The invention further pertains to vectors comprising these polynucleotides and host cells containing such vectors. The invention provides a method for producing the modified enzyme and a method for producing riboflavin, a riboflavin precursor, FMN, FAD, or a derivative thereof.
摘要翻译： 本发明涉及显示增加的比活性的改良的GTP环化水解酶II酶和编码它们的多核苷酸。 本发明还涉及包含这些多核苷酸的载体和含有这些载体的宿主细胞。 本发明提供一种生产该修饰酶的方法和一种生产核黄素，核黄素前体，FMN，FAD或其衍生物的方法。
-
公开(公告)号：US20080193998A1
公开(公告)日：2008-08-14
申请号：US11631542
申请日：2005-07-07
CPC分类号： C12N9/78
摘要： The present invention relates to modified GTP cyclohydrolase II enzymes that display increased specific activity, and to polynucleotides encoding them. The invention further pertains to vectors comprising these polynucleotides and host cells containing such vectors. The invention provides a method for producing the modified enzyme and a method for producing riboflavin, a riboflavin precursor, FMN, FAD, or a derivative thereof.
摘要翻译： 本发明涉及显示增加的比活性的改良的GTP环化水解酶II酶和编码它们的多核苷酸。 本发明还涉及包含这些多核苷酸的载体和含有这些载体的宿主细胞。 本发明提供一种生产该修饰酶的方法和一种生产核黄素，核黄素前体，FMN，FAD或其衍生物的方法。
-
3.发明授权公开(公告)号：US08349615B2
公开(公告)日：2013-01-08
申请号：US11762119
申请日：2007-06-13
CPC分类号： G01N30/28 , B01D15/08 , B01D15/203 , G01N30/466 , G01N30/8658 , G01N2030/009
摘要： The invention relates to a method of finding suitable parameters for the chromatographic purification of biomolecules. The method consists of equilibration, charging, washing and eluting steps, this sequence of steps being carried out by the partial batch method. The parameters determined in small, preferably numerous parallel test batches provide conclusions as to the chromatography conditions under which a given biomolecule can be purified optimally by column chromatography, optionally even on a larger scale.
摘要翻译： 本发明涉及一种寻找生物分子层析纯化的合适参数的方法。 该方法由平衡，充电，洗涤和洗脱步骤组成，该步骤的顺序通过部分分批方法进行。 在小的，优选多个平行测试批次中确定的参数提供关于色谱条件的结论，在此条件下，可以通过柱色谱法，甚至更大规模可以最佳地纯化给定的生物分子。
-
4.发明申请公开(公告)号：US20080066530A1
公开(公告)日：2008-03-20
申请号：US11762119
申请日：2007-06-13
IPC分类号： G01N30/84
CPC分类号： G01N30/28 , B01D15/08 , B01D15/203 , G01N30/466 , G01N30/8658 , G01N2030/009
摘要： The invention relates to a method of finding suitable parameters for the chromatographic purification of biomolecules. The method consists of equilibration, charging, washing and eluting steps, this sequence of steps being carried out by the partial batch method. The parameters determined in small, preferably numerous parallel test batches provide conclusions as to the chromatography conditions under which a given biomolecule can be purified optimally by column chromatography, optionally even on a larger scale.
摘要翻译： 本发明涉及一种寻找生物分子层析纯化的合适参数的方法。 该方法由平衡，充电，洗涤和洗脱步骤组成，该步骤的顺序通过部分分批方法进行。 在小的，优选多个平行测试批次中确定的参数提供关于色谱条件的结论，在此条件下，可以通过柱色谱法，甚至更大规模可以最佳地纯化给定的生物分子。
-
-
-
搜索结果
4 条记录 (耗时 0.021 秒)
