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公开(公告)号：US20220354564A1
公开(公告)日：2022-11-10
申请号：US17738257
申请日：2022-05-06
Applicant: The Cleveland Clinic Foundation
Inventor： Tolga Erim , Tanju Erim , Shengqiang Gao
Abstract: An endoscopic instrument containing a retractable tool at its end that is articulated by engaging an actuator that moves pull wires to angularly move the tip of the instrument along a plane for conducting a procedure at a target site. The tool of instrument is linearly move from an extension position to a retracted position by another actuator. The instrument provide rotational control of the tool and instrument tip portion with a rotational actuator for rotating housings that carry both pull wires and a conducting wire connected to the tool.
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公开(公告)号：US20190175163A1
公开(公告)日：2019-06-13
申请号：US16279141
申请日：2019-02-19
Applicant: THE CLEVELAND CLINIC FOUNDATION
Inventor： Amit Bhatt , Shengqiang Gao , William Kolosi , John Vargo
IPC: A61B17/02
Abstract: Systems, methods, and apparatuses for assisting with submucosal dissections include a retraction strip body. The retraction strip body is formed at least partially from a deformable material. The retraction strip body is capable of being selectively moved between a first condition and a second condition. In the first condition, the retraction strip body is capable of engaging a target patient tissue. In the second condition, the retraction strip body is capable of retracting the target patient tissue. At least one tissue engagement member is located on the retraction strip body.
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公开(公告)号：US20140207027A1
公开(公告)日：2014-07-24
申请号：US14161908
申请日：2014-01-23
Applicant: THE CLEVELAND CLINIC FOUNDATION
Inventor： Jose L. Navia , Shengqiang Gao
CPC classification number: A61F13/00068 , A61H7/00 , A61M1/0084 , A61M1/0088
Abstract: Various embodiments of a wound cover apparatus are provided. In one embodiment a wound cover apparatus includes a treatment enclosure and a vacuum seal that is external to the treatment enclosure. The vacuum seal includes a vacuum passageway and a vacuum port in fluid communication with one another. In another embodiment the apparatus further includes a treatment port in fluid communication with the treatment enclosure. The wound cover apparatus adheres to the patient by application of vacuum applied to the treatment enclosure and the vacuum seal which extends from the housing. The negative pressure applied to the wound cover apparatus creates negative stress along periwound which promotes perfusion and vascularization and induces mechanical deformation to accelerate healing.
Abstract translation: 提供伤口罩装置的各种实施例。 在一个实施例中，伤口覆盖装置包括治疗外壳和位于治疗外壳外部的真空密封件。 真空密封件包括彼此流体连通的真空通道和真空端口。 在另一个实施例中，该装置还包括与治疗外壳流体连通的治疗口。 伤口覆盖装置通过施加施加到治疗外壳上的真空和从壳体延伸的真空密封而粘附到患者身上。 施加到伤口覆盖装置上的负压沿着围绕产生负应力，促进灌注和血管化，并引起机械变形以加速愈合。
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公开(公告)号：US12226167B2
公开(公告)日：2025-02-18
申请号：US17868282
申请日：2022-07-19
Applicant: The Cleveland Clinic Foundation
Inventor： Sean J. Nagel , Mark D. Bain , Stephen Jones , Shengqiang Gao
Abstract: Systems and methods for sonicating a body within an organ of a patient include supplying ultrasound energy to the body in order to produce a liquified material, which can then be aspirated from the body via a catheter. Image guidance is used during aspiration of the liquified material.
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公开(公告)号：US11957351B2
公开(公告)日：2024-04-16
申请号：US17522709
申请日：2021-11-09
Applicant: THE CLEVELAND CLINIC FOUNDATION
Inventor： Nizar Zein , Shengqiang Gao
CPC classification number: A61B17/12013 , A61B17/2909 , A61B2017/00778 , A61B2017/00818 , A61B2017/291
Abstract: Tissue ligation systems and methods are provides to mechanically strangulate abnormal or undesirable tissue. Tissue ligation systems include a multi-lumen catheter having an outer diameter smaller than the inner diameter of a standard endoscope channel such that the catheter can be inserted into the endoscope. Tissue ligation systems also include a ligation apparatus with an expandable hood disposed at the distal end of the catheter. A suture extends through a lumen of the catheter and has a distal loop portion that can strangulate tissue.
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Patent Agency Ranking
公开(公告)号：US10939999B2
公开(公告)日：2021-03-09
申请号：US16025977
申请日：2018-07-02
Applicant: THE CLEVELAND CLINIC FOUNDATION
Inventor： Jose L. Navia , Ji-Feng Chen , Shengqiang Gao , Brian L. Davis , Samantha Stucke
IPC: A61F2/24
Abstract: An apparatus for replacing a diseased cardiac valve is movable from a radially collapsed configuration to a radially expanded configuration. The apparatus comprises an expandable support member and a prosthetic valve secured therein. The main body portion extends between first and second end portions and includes an outer circumferential surface, a circumferential axis extending about the circumferential surface, and a plurality of wing members spaced apart from one another by an expandable region. Each of the wing members includes first and second end portions and a flexible middle portion extending between the end portions. The second end portion is integrally formed with the uyimain body portion. The first end portion is adjacent the circumferential axis and substantially flush with the outer circumferential surface in the radially collapsed configuration. The first end portion extends substantially radial to the outer circumferential surface in the radially expanded configuration.
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公开(公告)号：US20190008632A1
公开(公告)日：2019-01-10
申请号：US16025977
申请日：2018-07-02
Applicant: THE CLEVELAND CLINIC FOUNDATION
Inventor： Jose L. Navia , Ji-Feng Chen , Shengqiang Gao , Brian L. Davis , Samantha Stucke
IPC: A61F2/24
Abstract: An apparatus for replacing a diseased cardiac valve is movable from a radially collapsed configuration to a radially expanded configuration. The apparatus comprises an expandable support member and a prosthetic valve secured therein. The main body portion extends between first and second end portions and includes an outer circumferential surface, a circumferential axis extending about the circumferential surface, and a plurality of wing members spaced apart from one another by an expandable region. Each of the wing members includes first and second end portions and a flexible middle portion extending between the end portions. The second end portion is integrally formed with the uyimain body portion. The first end portion is adjacent the circumferential axis and substantially flush with the outer circumferential surface in the radially collapsed configuration. The first end portion extends substantially radial to the outer circumferential surface in the radially expanded configuration.
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公开(公告)号：US20180289936A1
公开(公告)日：2018-10-11
申请号：US16002557
申请日：2018-06-07
Applicant: THE CLEVELAND CLINIC FOUNDATION
Inventor： Francis A. Papay , Ji-Feng Chen , Shengqiang Gao
Abstract: A system is provided for healing a wound. The system includes a flexible body, a therapeutic agent delivery mechanism, a suction mechanism, and a power source. The flexible body includes a cover film having oppositely disposed first and second surfaces that define a compartment. The compartment includes a first porous material, a second porous material, and at least one electrode disposed therein. The second porous material is disposed between the first porous material and the at least one electrode. The therapeutic agent delivery mechanism and the suction mechanism are fluidly connected to the compartment. The power source is in electrical communication with the at least one electrode.
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公开(公告)号：US10004881B2
公开(公告)日：2018-06-26
申请号：US15292285
申请日：2016-10-13
Applicant: THE CLEVELAND CLINIC FOUNDATION
Inventor： Francis A. Papay , Ji-Feng Chen , Shengqiang Gao
Abstract: A system is provided for healing a wound. The system includes a flexible body, a therapeutic agent delivery mechanism, a suction mechanism, and a power source. The flexible body includes a cover film having oppositely disposed first and second surfaces that define a compartment. The compartment includes a first porous material, a second porous material, and at least one electrode disposed therein. The second porous material is disposed between the first porous material and the at least one electrode. The therapeutic agent delivery mechanism and the suction mechanism are fluidly connected to the compartment. The power source is in electrical communication with the at least one electrode.
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公开(公告)号：US09907941B2
公开(公告)日：2018-03-06
申请号：US14804427
申请日：2015-07-21
Applicant: THE CLEVELAND CLINIC FOUNDATION
Inventor： Michael A. Vogelbaum , Shengqiang Gao , William Kolosi
CPC classification number: A61M37/00 , A61M25/00 , A61M2025/0031 , A61M2025/0042 , A61M2025/028 , A61M2205/04 , A61M2210/0693
Abstract: A convection enhanced delivery device comprises a support member and an elongated microcatheter carried by the support member. The microcatheter projects lengthwise away from the support member. The microcatheter includes a catheter lumen extending in a first direction. A fluid conduit carried by the support member. The fluid conduit includes a conduit lumen that extends in a second direction different than the first direction. The conduit lumen is in fluid communication with the catheter lumen. An inlet port and a connecting port are also carried by the support member. The inlet port is in fluid communication with the fluid conduit. The connecting port is separate from the inlet port and is in fluid communication with the fluid conduit. The connecting port is configured to engage an end portion of an external fluid conduit such that the external fluid conduit projects away from the connecting port and from the support member.
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