公开(公告)号：US12036421B2

公开(公告)日：2024-07-16

申请号：US18563813

申请日：2022-05-25

Applicant: THE TRUSTEES OF DARTMOUTH COLLEGE

Inventor： Petr Bruza ,  Brian Pogue ,  Ramish Ashraf ,  Rongxiao Zhang ,  David Gladstone ,  Megan Clark ,  Roman Vasyltsiv

IPC: A61N5/10

CPC classification number: A61N5/1031 ,  A61N5/1049 ,  A61N5/1067 ,  A61N5/1071 ,  A61N2005/1059

Abstract: A system for delivering ultra-high dose rate irradiation to a target area of a patient, includes a pulsed charged-particle source along a beam axis; a collimator for shaping the beam of radiation; one or more cameras for imaging the target area of the patient; and a dosimetry controller for providing control signals to the charged-particle source one or more dosimeters positioned between an output of the charged-particle source and the collimator in beam fringes for measuring a radiation dosage provided by each pulse; and a beam scanning coil positioned between the collimator and the patient for directing the shaped beam. The dosimetry controller receives feedback from the one or more dosimeters and provides control signals to the particle source and the beam scanning coil that modulate final pulses in the series of pulses in real-time.