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公开(公告)号：US20160168601A1
公开(公告)日：2016-06-16
申请号：US15051710
申请日：2016-02-24
发明人： Takashi Mimitsuka , Kentaro Ishii , Ken Morita , Masashi Higasa , Kenji Sawai , Hideki Sawai , Katsushige Yamada , Shinichi Minegishi
IPC分类号： C12P7/56
CPC分类号： C12P7/56 , C12M29/18 , C12M47/10 , C12N9/00 , C12P1/00 , C12P7/02 , C12P7/40 , C12P13/001 , C12P13/04 , C12P13/08 , C12P19/34 , C12P21/02
摘要： A method of producing a chemical product includes cultivating microorganisms or culture cells in a fermentation tank; transferring a culture liquid from the fermentation tank to a membrane separation tank to filter the culture liquid through a separation membrane; and collecting a fermentation product from a filtration liquid as the chemical product while refluxing an unfiltered culture liquid that has not been filtered to be joined to the culture liquid on an upstream side of the membrane separation tank, wherein one portion of the culture liquid to be transferred from the fermentation tank is allowed to bypass the membrane separation tank depending on a pressure at a culture liquid flow-in side of the membrane separation tank.
摘要翻译： 生产化学产品的方法包括在发酵罐中培养微生物或培养细胞; 将培养液从发酵罐转移到膜分离罐中，通过分离膜过滤培养液; 并从作为化学产品的过滤液中收集发酵产物，同时在膜分离罐的上游侧回流未过滤的待过滤培养液与培养液接合的培养液，其中一部分培养液为 从膜分离罐的培养液流入侧的压力，允许从发酵罐转移到膜分离槽旁路。
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公开(公告)号：US10428358B2
公开(公告)日：2019-10-01
申请号：US15051710
申请日：2016-02-24
发明人： Takashi Mimitsuka , Kentaro Ishii , Ken Morita , Masashi Higasa , Kenji Sawai , Hideki Sawai , Katsushige Yamada , Shinichi Minegishi
IPC分类号： C12P7/56 , C12M1/00 , C12N9/00 , C12P1/00 , C12P7/02 , C12P7/40 , C12P13/00 , C12P13/04 , C12P13/08 , C12P19/34 , C12P21/02
摘要： A method of producing a chemical product includes cultivating microorganisms or culture cells in a fermentation tank; transferring a culture liquid from the fermentation tank to a membrane separation tank to filter the culture liquid through a separation membrane; and collecting a fermentation product from a filtration liquid as the chemical product while refluxing an unfiltered culture liquid that has not been filtered to be joined to the culture liquid on an upstream side of the membrane separation tank, wherein one portion of the culture liquid to be transferred from the fermentation tank is allowed to bypass the membrane separation tank depending on a pressure at a culture liquid flow-in side of the membrane separation tank.
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公开(公告)号：US10370633B2
公开(公告)日：2019-08-06
申请号：US14899624
申请日：2014-06-23
摘要： A continuous sterilizing apparatus circulates, through members constituting a flow channel, a sterilizing medium that sterilizes the members to sterilize the members, circulates a sterilizing liquid subjected to sterilization treatment through pipes, performs a series of pieces of treatment including heating treatment, holding treatment, and cooling treatment on the sterilizing liquid, controls a flow rate, a temperature, and a pressure to be preset conditions, and switches a liquid to be circulated through the flow channel from the sterilizing liquid to a liquid to be sterilized.
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4.发明申请METHOD OF OPERATING CONTINUOUS STERILIZING APPARATUS, CONTINUOUS STERILIZING APPARATUS, FERMENTING SYSTEM, AND CONTINUOUS FERMENTING SYSTEM 审中-公开连续灭菌装置，连续灭菌装置，发生系统和连续发生系统的操作方法公开(公告)号：US20160145559A1
公开(公告)日：2016-05-26
申请号：US14899624
申请日：2014-06-23
CPC分类号： C12M37/00 , A23L3/22 , A23V2002/00 , A61L2/07 , C12M33/14 , C12M41/00 , C12M41/12 , C12M41/40 , C12M45/00 , C12M45/20 , C12M47/16
摘要： A continuous sterilizing apparatus circulates, through members constituting a flow channel, a sterilizing medium that sterilizes the members to sterilize the members, circulates a sterilizing liquid subjected to sterilization treatment through pipes, performs a series of pieces of treatment including heating treatment, holding treatment, and cooling treatment on the sterilizing liquid, controls a flow rate, a temperature, and a pressure to be preset conditions, and switches a liquid to be circulated through the flow channel from the sterilizing liquid to a liquid to be sterilized.
摘要翻译： 连续灭菌装置通过构成流路的构件循环灭菌所述构件灭菌的消毒介质，对通过管进行灭菌处理的灭菌液进行循环，进行一系列处理，包括加热处理，保持处理， 对灭菌液进行冷却处理，将流量，温度和压力控制为预先设定的条件，并将通过流路的循环液从灭菌液切换成待灭菌的液体。
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