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27 条记录 (耗时 0.025 秒)

    Process for producing image using laminated oriented cover film
    2.
    发明授权
    Process for producing image using laminated oriented cover film 失效
    使用层压取向覆盖膜制作图像的方法

    公开(公告)号：US4211560A

    公开(公告)日：1980-07-08

    申请号：US923763

    申请日：1978-07-11

    申请人： Tadashi Taguchi ,  Noboru Fujikawa ,  Mitsuo Kohno ,  Katsumi Yoshitake ,  Kunio Satake

    发明人： Tadashi Taguchi ,  Noboru Fujikawa ,  Mitsuo Kohno ,  Katsumi Yoshitake ,  Kunio Satake

    IPC分类号： G03F7/09 ,  G03F7/095 ,  G03F7/26 ,  H05K3/00 ,  H05K3/06 ,  G03C5/00 ,  G03C1/76

    CPC分类号： H05K3/064 ,  G03F7/092 ,  G03F7/0955 ,  G03F7/26 ,  H05K2201/0108 ,  H05K2203/0783 ,  H05K2203/1394 ,  H05K3/0082 ,  H05K3/0094 ,  Y10S430/136 ,  Y10S430/14 ,  Y10S430/162

    摘要： A process for producing an image which comprises the steps of:(1) applying to the surface of a substrate the surface of a photosensitive layer, the other surface of the photosensitive layer being adhered to a substantially transparent film support which is soluble or dispersible in a developer consisting essentially of a liquid capable of substantially dissolving or dispersing therein the areas of the layer other than those having a polymeric image produced by imagewise exposure in the step (2) below;(2) exposing the photosensitive layer, imagewise, to actinic radiation to form a polymeric image in the layer; and(3) washing away with the developer the film support and the areas of the layer other than those having the polymeric image to form an image of a polymeric material on the substrate. The photosensitive element having on its one side the above-mentioned specific film support and the process have a variety of applications and are useful for producing photoresists which are advantageously used for making printed circuit boards.

    摘要翻译： 一种用于制造图像的方法，包括以下步骤：（1）将感光层的表面施加到基底的表面，感光层的另一表面粘附到可溶或可分散于 基本上由在下面的步骤（2）中能够基本上溶解或分散其中除了具有通过成像曝光产生的聚合物图像的层之外的层的区域的液体的显影剂; （2）将感光层成像曝光于光化辐射以在层中形成聚合物图像; 和（3）用显影剂除去膜载体和不同于具有聚合物图像的那些层的区域，以在基底上形成聚合物材料的图像。 感光元件的一侧具有上述特定的膜支撑体，并且该方法具有各种应用，并且可用于制造有利地用于制造印刷电路板的光致抗蚀剂。

    Oriented polystyrene support for photopolymerizable element
    3.
    发明授权
    Oriented polystyrene support for photopolymerizable element 失效
    用于光聚合元件的取向聚苯乙烯支撑体

    公开(公告)号：US4301230A

    公开(公告)日：1981-11-17

    申请号：US104944

    申请日：1979-12-18

    申请人： Tadashi Taguchi ,  Noboru Fujikawa ,  Mitsuo Kohno ,  Katsumi Yoshitake ,  Kunio Satake

    发明人： Tadashi Taguchi ,  Noboru Fujikawa ,  Mitsuo Kohno ,  Katsumi Yoshitake ,  Kunio Satake

    IPC分类号： G03F7/09 ,  G03F7/095 ,  G03F7/26 ,  H05K3/00 ,  H05K3/06 ,  G03C1/76 ,  G03C1/78 ,  G03C3/00

    CPC分类号： H05K3/064 ,  G03F7/092 ,  G03F7/0955 ,  G03F7/26 ,  H05K2201/0108 ,  H05K2203/0783 ,  H05K2203/1394 ,  H05K3/0082 ,  H05K3/0094 ,  Y10S430/136 ,  Y10S430/14 ,  Y10S430/162

    摘要： A process for producing an image which comprises the steps of:(1) applying to the surface of a substrate the surface of a photosensitive layer, the other surface of the photosensitive layer being adhered to a substantially transparent film support which is soluble or dispersible in a developer consisting essentially of a liquid capable of substantially dissolving or dispersing therein the areas of the layer other than those having a polymeric image produced by imagewise exposure in the step (2) below;(2) exposing the photosensitive layer, imagewise, to actinic radiation to form a polymeric image in the layer; and(3) washing away with the developer the film support and the areas of the layer other than those having the polymeric image to form an image of a polymeric material on the substrate. The photosensitive element having on its one side the above-mentioned specific film support and the process have a variety of applications and are useful for producing photoresists which are advantageously used for making printed circuit boards.

    摘要翻译： 一种用于制造图像的方法，包括以下步骤：（1）将感光层的表面施加到基底的表面，感光层的另一表面粘附到可溶或可分散于 基本上由在下面的步骤（2）中能够基本上溶解或分散其中除了具有通过成像曝光产生的聚合物图像的层之外的层的区域的液体的显影剂; （2）将感光层成像曝光于光化辐射以在层中形成聚合物图像; 和（3）用显影剂除去膜载体和不同于具有聚合物图像的那些层的区域，以在基底上形成聚合物材料的图像。 感光元件的一侧具有上述特定的膜支撑体，并且该方法具有各种应用，并且可用于制造有利地用于制造印刷电路板的光致抗蚀剂。

    Process for preparing 1,4-dihydropyridine compounds
    4.
    发明授权
    Process for preparing 1,4-dihydropyridine compounds 失效
    制备1,4-二氢吡啶化合物的方法

    公开(公告)号：US06649767B2

    公开(公告)日：2003-11-18

    申请号：US10224928

    申请日：2002-08-20

    申请人： Kunio Satake ,  Noriaki Murase

    发明人： Kunio Satake ,  Noriaki Murase

    IPC分类号： C07D21302

    CPC分类号： C07D417/06

    摘要： A process for preparing a 1,4-dihydropyridine compound comprising contacting an enamine compound and a compound having a structure of in the presence of a base; and treating the reaction mixture thus obtained in the presence of an acid or a combination of acids under mild reaction conditions. A resulting 1,4-dihydropyridine compound is useful as an anti-inflammatory agent or the like.

    摘要翻译： 一种制备1,4-二氢吡啶化合物的方法，包括使烯胺化合物和具有在碱存在下的结构的化合物接触; 并在温和的反应条件下，在酸或酸的组合存在下处理由此得到的反应混合物。 得到的1,4-二氢吡啶化合物可用作抗炎剂等。

    Substituted benzylaminopiperidine compounds
    5.
    发明授权
    Substituted benzylaminopiperidine compounds 失效
    取代的苄基氨基哌啶化合物

    公开(公告)号：US06506775B1

    公开(公告)日：2003-01-14

    申请号：US09564398

    申请日：2000-05-01

    申请人： Kunio Satake ,  Yuji Shishido ,  Hiroaki Wakabayashi

    发明人： Kunio Satake ,  Yuji Shishido ,  Hiroaki Wakabayashi

    IPC分类号： C07D21156

    CPC分类号： C07D211/56

    摘要： The invention provides a compound of formula (I): and its pharmaceutically acceptable salts, wherein R is halo C2-C8 alkenyl or halo C2-C8 alkynyl; R1 is hydrogen, halo or C1-C6 alkoxy; or R and R1, together with the two carbon atoms to which they are attached, form a C4-C6 cycloalkyl or a C4-C6 oxacycloalkyl ring wherein said ring may be optionally substituted by one or more substituents selected from the group consisting of halo, C1-C6 alkyl and halo C1-C6 alkyl; X is C1-C6 alkoxy, halo C1-C6 alkoxy, phenoxy or halo; and Ar is phenyl optionally substituted by halo. These compounds are useful in the treatment of a gastrointestinal disorder; a central nervous system (CNS) disorder; an inflammatory disease; emesis; urinary incontinence; pain; migraine; sunburn; diseases, disorders and adverse conditions caused by Heliobacter pylori; or angiogenesis especially CNS disorders in a mammalian subject, especially humans.

    摘要翻译： 本发明提供式（I）化合物及其药学上可接受的盐，其中R为卤代C 2 -C 8烯基或卤代C 2 -C 8炔基; R 1为氢，卤素或C 1 -C 6烷氧基;或R和R 1与 它们连接的两个碳原子形成C 4 -C 6环烷基或C 4 -C 6氧杂环烷基环，其中所述环可任选地被一个或多个选自卤素，C 1 -C 6烷基和卤代C 1 -C 6烷基的取代基取代， C6烷基; X是C1-C6烷氧基，卤代C1-C6烷氧基，苯氧基或卤代; 并且Ar是任选被卤素取代的苯基。这些化合物可用于治疗胃肠道疾病; 中枢神经系统（CNS）障碍; 炎性疾病; 呕吐 尿失禁 疼痛; 偏头痛 晒斑; 由幽门螺杆菌引起的疾病，病症和不良状况; 或血管发生，尤其是哺乳动物受试者尤其是人类的CNS疾病。

    5-substituted picolinic acid compounds and their method of use
    7.
    发明授权
    5-substituted picolinic acid compounds and their method of use 失效
    5-取代吡啶甲酸化合物及其使用方法

    公开(公告)号：US06194442B1

    公开(公告)日：2001-02-27

    申请号：US09460483

    申请日：1999-12-14

    申请人： Hideo Hirai ,  Katsuomi Ichikawa ,  Nakao Kojima ,  Hiroyuki Nishida ,  Kunio Satake ,  Nobuji Yoshikawa

    发明人： Hideo Hirai ,  Katsuomi Ichikawa ,  Nakao Kojima ,  Hiroyuki Nishida ,  Kunio Satake ,  Nobuji Yoshikawa

    IPC分类号： A61K3144

    CPC分类号： A61K31/44 ,  Y02A50/411

    摘要： The present invention provides novel 5-substituted picolinic acid compounds of formula (I) or a pharmaceutically acceptable salt thereof: wherein R1 and R2 are independently H, C2-C6 acyl or halo-substituted benzoyl; and R3 is —C(O)O—C1-C6 alkyl, C(O)OH, CN, CONH2, CONHCH3, CON(CH3)2, 1-methyltetrazole or 2-methyltetrazole, with the proviso that when R2 is acetyl and R3 is methoxycarbonyl, R1 is not H; and that when R3 is CN, CONH2, CONHCH3, CON(CH3)2, 1-methyltetrazole or 2-methyltetrazole, R1 and R2 are H. The present invention also relates to a pharmaceutical composition comprising compound of the present invention, which is useful in the treatment of IL-1 and TNF mediated diseases or the like. The present invention further relates to a process for producing the compounds of the formula (I).

    摘要翻译： 本发明提供式（I）的新的5-取代的吡啶甲酸化合物或其药学上可接受的盐：其中R 1和R 2独立地为H，C 2 -C 6酰基或卤素取代的苯甲酰基; 并且R 3是-C（O）O-C 1 -C 6烷基，C（O）OH，CN，CONH 2，CONHCH 3，CON（CH 3）2,1-甲基四唑或2-甲基四唑，条件是当R 2是乙酰基和 R3是甲氧基羰基，R1不是H; 当R3为CN，CONH2，CONHCH3，CON（CH3）2,1-甲基四唑或2-甲基四唑时，R 1和R 2为H.本发明还涉及含有本发明化合物的药物组合物，其有用 在治疗IL-1和TNF介导的疾病等中。本发明还涉及制备式（I）化合物的方法。

    Tetrazolyl-substituted quinuclidines as substance P antagonists
    10.
    发明授权
    Tetrazolyl-substituted quinuclidines as substance P antagonists 失效
    作为物质P拮抗剂的四唑基取代的奎宁子

    公开(公告)号：US5939434A

    公开(公告)日：1999-08-17

    申请号：US924171

    申请日：1997-09-05

    申请人： Kunio Satake

    发明人： Kunio Satake

    IPC分类号： A61K31/435 ,  A61K31/439 ,  A61P1/00 ,  A61P1/04 ,  A61P1/08 ,  A61P9/00 ,  A61P13/00 ,  A61P13/02 ,  A61P15/00 ,  A61P17/02 ,  A61P25/00 ,  A61P25/04 ,  A61P25/06 ,  A61P29/00 ,  A61P31/04 ,  A61P37/08 ,  A61P43/00 ,  C07D453/02 ,  A61K31/44

    CPC分类号： C07D453/02

    摘要： This invention provides a compound of the formula: ##STR1## and its pharmaceutically acceptable salts, wherein R.sup.1 is halo, C.sub.1 -C.sub.6 alkyl, halo C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 alkoxy or halo C.sub.1 -C.sub.6 alkoxy; R.sup.2 is hydrogen, C.sub.1 -C.sub.6 alkyl, halo C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 alkyl-S-, C.sub.1 -C.sub.6 alkyl-SO--, C.sub.1 -C.sub.6 alkyl-SO.sub.2 --, cyclopropyl, phenyl, --NH.sub.2, --NH(CH.sub.3), --NHC(.dbd.O)CH.sub.3, --N(CH.sub.3).sub.2, --N(C.sub.2 H.sub.5).sub.2 or --CH.sub.2 C(.dbd.O)CF.sub.3 ; Ar.sup.1 and Ar.sup.2 are independently phenyl, halophenyl or thienyl; X is NH, O or S; and Y is hydrogen, --COOR.sup.3 or --CONR.sup.4 R.sup.5, wherein R.sup.3, R.sup.4 and R.sup.5 are independently hydrogen or C.sub.1 -C.sub.6 alkyl. These compounds are useful as analgesics or anti-inflammatory agents, or in the treatment of allergic disorders, angiogenesis, CNS disorders, emesis, gastrointestinal disorders, sunburn, urinary incontinence, or diseases, disorders or adverse conditions caused by Helicobacter pylori, or the like, in a mammalian subject, especially human, especially as analgesics or anti-inflammatory agents in the periphery.

    摘要翻译： 本发明提供下式化合物及其药学上可接受的盐，其中R 1为卤素，C 1 -C 6烷基，卤代C 1 -C 6烷基，C 1 -C 6烷氧基或卤代C 1 -C 6烷氧基; R2是氢，C1-C6烷基，卤代C1-C6烷基，C1-C6烷基-S-，C1-C6烷基-SO-，C1-C6烷基-SO2-，环丙基，苯基，-NH2，-NH（CH3 ），-NHC（= O）CH 3，-N（CH 3）2，-N（C 2 H 5）2或-CH 2 C（= O）CF 3; Ar1和Ar2独立地是苯基，卤代苯基或噻吩基; X是NH，O或S; 并且Y是氢，-COOR 3或-CONR 4 R 5，其中R 3，R 4和R 5独立地是氢或C 1 -C 6烷基。 这些化合物可用作止痛剂或抗炎剂，或用于治疗过敏性疾病，血管生成，CNS紊乱，呕吐，胃肠道疾病，晒伤，尿失禁或由幽门螺杆菌引起的疾病，病症或不利条件等 ，在哺乳动物受试者，特别是人类，特别是在周边的止痛剂或抗炎剂。