利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

7 条记录 (耗时 0.026 秒)

    Avian herpesvirus-based recombinant Infectious Bursal Disease vaccine
    1.
    发明授权
    Avian herpesvirus-based recombinant Infectious Bursal Disease vaccine 有权
    禽疱疹病毒重组传染性法氏囊病疫苗

    公开(公告)号：US07153511B2

    公开(公告)日：2006-12-26

    申请号：US10832353

    申请日：2004-04-27

    申请人： Takanori Sato ,  Yoshinari Tsuzaki ,  Motoyuki Esaki ,  Kristi M. Dorsey

    发明人： Takanori Sato ,  Yoshinari Tsuzaki ,  Motoyuki Esaki ,  Kristi M. Dorsey

    IPC分类号： A61K39/12

    CPC分类号： C12N7/00 ,  A61K39/12 ,  A61K2039/5256 ,  A61K2039/55 ,  A61K2039/552 ,  C12N2710/16321 ,  C12N2720/10034 ,  Y10S424/816

    摘要： The present invention provides an avian recombinant herpesvirus modified by the presence of the cDNA encoding, the VP2 of the Delaware Variant E strain of IBDV, a subtype of IBDV serotype 1 strains. The present invention further provides an avian recombinant herpesvirus comprised of the VP2 gene of which the backbone virus is a Marek's disease vaccine strain, such as herpesvirus of turkeys. A poultry vaccine including the avian herpes recombinant virus described in the present invention can induce in chickens protective immunity against a variety of different subtypes of IBDV.

    摘要翻译： 本发明提供了通过编码IBDV的Delaware变体E株的VP2，IBDV血清型1株亚型的cDNA的存在而修饰的禽重组疱疹病毒。 本发明还提供了由VP2基因组成的禽类重组疱疹病毒，其中主要病毒是马立克氏病疫苗株，例如火鸡疱疹病毒。 包括本发明中描述的禽疱疹重组病毒的家禽疫苗可诱导针对IBDV的各种不同亚型的鸡的保护性免疫。

    AVIAN VACCINES POSSESSING A POSITIVE MARKER GENE
    2.
    发明申请
    AVIAN VACCINES POSSESSING A POSITIVE MARKER GENE 审中-公开

    公开(公告)号：US20110311994A1

    公开(公告)日：2011-12-22

    申请号：US12448105

    申请日：2009-03-16

    申请人： Motoyuki Esaki ,  Takanori Sato ,  Kristi M. Dorsey

    发明人： Motoyuki Esaki ,  Takanori Sato ,  Kristi M. Dorsey

    IPC分类号： G01N33/53 ,  C12N7/01

    CPC分类号： A61K39/12 ,  A61K39/00 ,  A61K2039/5256 ,  A61K2039/552 ,  C12N2710/14122 ,  C12N2710/14134 ,  C12N2710/16343 ,  C12N2710/16371 ,  C12N2760/16122 ,  C12N2760/16134

    摘要： The present invention provides a poultry vaccine containing a positive marker gene. More specifically, recombinant turkey herpesvirus modified by the presence of an extraneous antigen gene that may be used as a positive marker to identify and track vaccinated animals is provided. When inoculated into host animals, a poultry vaccine comprising the recombinant turkey herpesvirus provided in the present invention can elicit serological immune responses to the marker gene product that may be detected by serological assays such as enzyme-linked immunosorbent assay and serum agglutination test, thus enabling easy identification and tracking of vaccinated animals.

    摘要翻译： 本发明提供含有阳性标记基因的家禽疫苗。 更具体地，提供了可以用作阳性标记物以鉴定和跟踪接种疫苗的动物的外来抗原基因存在而修饰的重组火鸡疱疹病毒。 当接种到宿主动物中时，包含本发明提供的重组火鸡疱疹病毒的家禽疫苗可引起可通过血清学检测如酶联免疫吸附测定和血清凝集试验检测的标记基因产物的血清学免疫应答，从而使 容易识别和跟踪疫苗接种的动物。

    Avian vaccines possessing a positive marker gene
    3.
    发明申请
    Avian vaccines possessing a positive marker gene 审中-公开
    具有阳性标记基因的禽类疫苗

    公开(公告)号：US20090246226A1

    公开(公告)日：2009-10-01

    申请号：US12078307

    申请日：2008-03-28

    申请人： Motoyuki Esaki ,  Takanori Sato ,  Kristi M. Dorsey

    发明人： Motoyuki Esaki ,  Takanori Sato ,  Kristi M. Dorsey

    IPC分类号： A61K39/245 ,  C12N7/01 ,  A61P31/22

    CPC分类号： A61K39/12 ,  A61K39/00 ,  A61K2039/5256 ,  A61K2039/552 ,  C12N2710/14122 ,  C12N2710/14134 ,  C12N2710/16343 ,  C12N2710/16371 ,  C12N2760/16122 ,  C12N2760/16134

    摘要： The present invention provides a poultry vaccine containing a positive marker gene. More specifically, recombinant turkey herpesvirus modified by the presence of an extraneous antigen gene that may be used as a positive marker to identify and track vaccinated animals is provided. When inoculated into host animals, a poultry vaccine comprising the recombinant turkey herpesvirus provided in the present invention can elicit serological immune responses to the marker gene product that may be detected by serological assays such as enzyme-linked immunosorbent assay and serum agglutination test, thus enabling easy identification and tracking of vaccinated animals.

    摘要翻译： 本发明提供含有阳性标记基因的家禽疫苗。 更具体地，提供了可以用作阳性标记物以鉴定和跟踪接种疫苗的动物的外来抗原基因存在而修饰的重组火鸡疱疹病毒。 当接种到宿主动物中时，包含本发明提供的重组火鸡疱疹病毒的家禽疫苗可引起可通过血清学检测如酶联免疫吸附测定和血清凝集试验检测的标记基因产物的血清学免疫应答，从而使 容易识别和跟踪疫苗接种的动物。