摘要:
A novel therapeutic agent for organ disease, in particular, a therapeutic agent for liver disease is provided.It has been found that a diarylsulfide or diarylether derivative having 2-amino-1,3-propanediol structure, the compound that act as a sphingosine-1-phosphate receptor agonist, and a pharmaceutically acceptable salt and hydrate thereof are used as effective therapeutic agents for various diseases in organs, in particular liver diseases. The diarylsulfide or diarylether derivative is represented by the following general formula (1):
摘要:
A method for treating a liver disease such as hepatitis, comprising administering to a patient having the liver disease, an effective amount of a diarylsulfide or diarylether derivative having 2-amino-1,3-propanediol structure, and represented by the following formula (1): or a pharmaceutically acceptable salt thereof.
摘要:
A softening apparatus includes a cooling liquid reservoir for holding a cooling liquid, a first conducting sheave provided outside of the cooling liquid reservoir for applying a voltage to a wire while guiding the wire, and a second conducting sheave provided in the cooling liquid reservoir for letting a current flow through the wire while guiding the wire as the wire is fed via the first conducting sheave. The softening apparatus is also provided with a liquid level detector for detecting a liquid level of the cooling liquid in the cooling liquid reservoir. A heating path length of the wire between the first conducting sheave and the second conducting sheave is controlled based on a result of detection by the liquid level detector.
摘要:
A multi unit controller has a plurality of base units each of which includes a control unit connector, a base unit connector through which the base units juxtaposed to each other are connected to each other, and a plurality of control units connected to the base units respectively through the respective control unit connector, wherein the base units juxtaposed vertically.
摘要:
A laser oscillator control device includes a controller having a transmitter section and a receiver section; a laser oscillator having a transmitter section and a receiver section and communicating with the controller via a communication line; wherein the laser oscillator control device outputs a control signal from the controller to the laser oscillator, based on a status signal indicating operational state of the laser oscillator sent from the laser oscillator to the controller. The controller has an alternating signal transmitter circuit that generates an alternating signal that changes at a predetermined period, and sends this alternating signal to the laser oscillator, and the laser oscillator has a return signal transmitter circuit which generates a return signal that changes periodically in correspondence to the alternating signal from the controller, and sends this return signal to the controller. Furthermore, the controller has a monitoring circuit monitoring the return signal from the laser oscillator, and if it determines that there is an abnormality in the return signal, outputs a stop control signal for stopping laser beam irradiation by the laser oscillator.
摘要:
A capstan device for taking up a braided wire in a braided wire manufacturing apparatus for braiding a plurality of wires to manufacture the braided wire. The capstan device includes a capstan roller having a tapered outer peripheral surface and provided with a flange portion on an end at a small diameter side thereof, and a guide member. The guide member has a first guide surface provided to be turned toward a large diameter side of the capstan roller in an axial direction of the capstan roller in a position on a larger diameter side than a portion having the smallest diameter in the tapered outer peripheral surface, and a second guide surface provided to be protruded from the first guide surface at an outer peripheral side of the tapered outer peripheral surface.
摘要:
The present invention provides an electric compressor in which a lead wire on the motor driving circuit side can be electrically connected positively to a sealed terminal. Because the sealed terminal is formed from a terminal body which is made of a metal having electrical conductivity and whose end is provided with a male threaded portion, and a joining nut made of a metal having electrical conductivity and which is different from the material for the terminal body, and is threadably mounted on the male threaded portion of the terminal body, it is possible to positively join the joining nut of a different material to the terminal body and to positively join the lead wire of the same material as the joining nut to the joining nut by welding, whereby it becomes possible to electrically connect a lead wire on the driving circuit housing chamber side positively to the sealed terminal.
摘要:
The present invention provides an artificial kidney precursor containing a non-human mammalian metanephros separated out from a living body, wherein the metanephros has been subjected to freezing and thawing treatments outside a living body, and contains mammalian mesenchymal stem cells transferred outside a living body, and a method of production thereof.
摘要:
A programmable electronic controller in which one central arithmetic processing unit and a plurality of input devices and output devices are connected by means of a parallel bus, the controller being basically configured to activate a self-diagnostic function and a diagnostic test of the input devices and the output devices with an instruction from a microprocessor of the central arithmetic processing unit; and to judge the result with the microprocessor of the central arithmetic processing unit, by using the microprocessor installed in the central arithmetic processing unit also as a processor for tests (diagnostic tests) of the self-diagnostic function of the input devices and output devices and conducting tests of the self-diagnostic function of the plurality of input devices and output devices with the central arithmetic processing unit.
摘要:
A polymerase activity is effectively enhanced by adding an anionic surfactant, in particular an anionic surfactant having a polyethoxyl group, to a reaction mixture containing a polymerase.