摘要:
The invention provides polymorphic human arylamine N-acetyltransferase (NAT) genes, more precisely a type 1 NAT gene containing the 5'-noncoding region base sequence of SEQ ID NO:1 and the coding region-containing base sequence of SEQ ID NO:2, a type 2 NAT gene containing the sequences of SEQ ID NO:3 and SEQ ID NO:4 and a type 3 NAT gene containing the sequences of SEQ ID NO:5 and SEQ ID NO:6, as well as a method of detecting these polymorphic genes and a method of diagnosing an adverse effect or effects to be caused by an amino-containing aromatic substance.
摘要翻译:本发明提供了多态性人芳胺N-乙酰转移酶(NAT)基因,更确切地说,是含有SEQ ID NO:1的5'-非编码区碱基序列和SEQ ID NO:2的编码区的碱基序列的1型NAT基因 ,含有SEQ ID NO:3和SEQ ID NO:4的序列的2型NAT基因和含有SEQ ID NO:5和SEQ ID NO:6的序列的3型NAT基因,以及检测方法 这些多态性基因和诊断由含氨基芳族物质引起的副作用或效果的方法。