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公开(公告)号：US06849432B2
公开(公告)日：2005-02-01
申请号：US09980102
申请日：2001-03-23
申请人： Takeya Abe , Kiyoshi Ito , Kenju Sasaki , Seiichi Watanabe , Toshihisa Tachibana , Tamotsu Asano
发明人： Takeya Abe , Kiyoshi Ito , Kenju Sasaki , Seiichi Watanabe , Toshihisa Tachibana , Tamotsu Asano
摘要： The invention is a process for continuously producing an amide compound by reacting a microorganism fungus body containing nitrile hydratase or a processed product of the microorganism fungus body with a nitrile compound in an aqueous medium, characterized in that after contacting said fungus body or said processed product of said fungus body with said nitrile compound in said aqueous medium, a reaction solution thus obtained is further subjected to reaction under conditions having a plug flow region, and according to the invention, an amide compound aqueous solution of a high concentration a high purity can be easily obtained in an extremely high conversion rate of a nitrile compound without a condensation process.
摘要翻译： 本发明是一种通过含腈水合酶的微生物菌体或微生物真菌体的加工产物与腈化合物在水性介质中反应来连续生产酰胺化合物的方法，其特征在于，在使所述真菌体或所述加工产物 的所述真菌体与所述腈化合物在所述水性介质中反应，得到的反应溶液在具有活塞流动区域的条件下进一步反应，根据本发明，高浓度高纯度的酰胺化合物水溶液 可以容易地以非常高的腈化合物的转化率而不会产生冷凝过程。
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公开(公告)号：US08329843B2
公开(公告)日：2012-12-11
申请号：US13197066
申请日：2011-08-03
申请人： Hiroko Shibamoto , Toshikazu Aikawa , Teruo Arii , Masanori Muramoto , Takeshi Fukuda , Kiyoshi Ito , Takeya Abe , Souichi Hazama
发明人： Hiroko Shibamoto , Toshikazu Aikawa , Teruo Arii , Masanori Muramoto , Takeshi Fukuda , Kiyoshi Ito , Takeya Abe , Souichi Hazama
CPC分类号： C12P13/00 , C07C231/06 , C08F220/56 , C12P13/02 , C07C233/09
摘要： A method for producing an amide compound from a nitrile compound in an aqueous medium in the presence of a catalyst having a nitrile hydratase activity wherein the concentration of benzene in the aqueous medium is 4.0 ppm or less and a method for producing an amide-based polymer excellent in quality from the amide compound. Also provided are a method for more efficiently producing an acrylamide with higher quality by a microbial catalyst containing a nitrile hydratase and the like and a method for producing an acrylamide-based polymer, which is excellent in hue, has a good balance between water solubility and high molecular weight and is excellent in quality.
摘要翻译： 在具有腈水合酶活性的催化剂存在下，在含水介质中由腈化合物制备酰胺化合物的方法，其中水介质中苯的浓度为4.0ppm或更低，以及制备酰胺基聚合物的方法 优异的酰胺化合物。 还提供了通过含有腈水合酶等的微生物催化剂更有效地制备具有更高质量的丙烯酰胺的方法和色调优异的丙烯酰胺类聚合物的制造方法，水溶性与 高分子量，质量优良。
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公开(公告)号：US20090171051A1
公开(公告)日：2009-07-02
申请号：US12089511
申请日：2006-10-06
申请人： Hiroko Shibamoto , Toshikazu Aikawa , Teruo Arii , Masanori Muramoto , Takeshi Fukuda , Kiyoshi Ito , Takeya Abe , Souichi Hazama
发明人： Hiroko Shibamoto , Toshikazu Aikawa , Teruo Arii , Masanori Muramoto , Takeshi Fukuda , Kiyoshi Ito , Takeya Abe , Souichi Hazama
CPC分类号： C12P13/00 , C07C231/06 , C08F220/56 , C12P13/02 , C07C233/09
摘要： [Problems] The present invention provides a method for efficiently producing a corresponding amide compound from a nitrile compound by a reaction using a nitrile hydratase and a method for producing an amide-based polymer excellent in quality from the amide compound. In addition, the present invention provides a method for more efficiently producing an acrylamide with higher quality by a microbial catalyst containing a nitrile hydratase and the like and a method for producing an acrylamide-based polymer, which is excellent in hue, has a good balance between the water solubility and the high molecular weight and is also excellent in quality, by using the acrylamide.[Means for Solving the Problems] The method for producing an amide compound of the present invention is characterized in that in a method for producing an amide compound from a nitrile compound in an aqueous medium in the presence of a catalyst having a nitrile hydratase activity, the concentration of benzene in the aqueous medium is 4.0 ppm or less. In addition, the method for producing an amide-based polymer of the present invention is characterized by homopolymerizing the amide compound or by copolymerizing the amide compound and at least unsaturated monomer copolymerizable with the amide compound. Further, the method for producing acrylamide of the present invention is characterized by hydrating acrylonitrile having a concentration of acrolein of 1 ppm or less by a microbial cell containing a nitrile hydratase or a processed product of the microbial cell in an aqueous medium. Furthermore, the method for producing an acrylamide-based polymer of the present invention is characterized by homopolymerizing the acrylamide or by copolymerizing the acrylamide and at least one unsaturated monomer copolymerizable with the acrylamide.
摘要翻译： 本发明提供一种通过使用腈水合酶的反应从腈化合物有效地制备相应的酰胺化合物的方法和由酰胺化合物质量优异的酰胺类聚合物的制备方法。 此外，本发明提供了一种通过含有腈水合酶等的微生物催化剂更有效地制备丙烯酰胺的方法以及色调优异的丙烯酰胺类聚合物的制造方法，其平衡性良好 在水溶性和高分子量之间，并且通过使用丙烯酰胺也具有优异的质量。 解决问题的手段本发明的酰胺化合物的制造方法的特征在于，在具有腈水合酶活性的催化剂存在下，在含水介质中由腈化合物制备酰胺化合物的方法中， 水介质中苯的浓度为4.0ppm以下。 此外，本发明的酰胺系聚合物的制造方法的特征在于，使酰胺化合物均聚，或者使酰胺化合物与至少与酰胺化合物可共聚的不饱和单体共聚。 此外，本发明的丙烯酰胺的制造方法的特征在于，通过含有腈水合酶的微生物细胞或微生物细胞的加工产物在水性介质中使丙烯醛浓度为1ppm以下的丙烯腈水合。 此外，本发明的丙烯酰胺类聚合物的制造方法的特征在于使丙烯酰胺均聚或通过共聚丙烯酰胺和至少一种与丙烯酰胺共聚的不饱和单体。
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4.发明申请Selective process for producing an anomer of a 1-phosphorylated saccharide derivative and process for producing a nucleoside 审中-公开用于制备1-磷酸化糖衍生物的异头物的选择性方法和用于制备核苷的方法公开(公告)号：US20060094869A1
公开(公告)日：2006-05-04
申请号：US11287212
申请日：2005-11-28
申请人： Hironori Komatsu , Hirokazu Awano , Nobuyuki Fukazawa , Kiyoshi Ito , Ichirou Ikeda , Tadashi Araki , Takeshi Nakamura , Tamotsu Asano , Junya Fujiwara , Tomoyuki Ando , Katsutoshi Tsuchiya , Kyoko Maruyama , Hideki Umetani , Takahiro Yamauchi , Hitoki Miyake
发明人： Hironori Komatsu , Hirokazu Awano , Nobuyuki Fukazawa , Kiyoshi Ito , Ichirou Ikeda , Tadashi Araki , Takeshi Nakamura , Tamotsu Asano , Junya Fujiwara , Tomoyuki Ando , Katsutoshi Tsuchiya , Kyoko Maruyama , Hideki Umetani , Takahiro Yamauchi , Hitoki Miyake
IPC分类号： C07H19/04
摘要： A desired isomer is selectively prepared by phosphorolyzing and isomerizing an anomer mixture of a 1-phosphorylated saccharide derivative while crystallizing one of the isomers to displace the equilibrium. Furthermore, using the action of a nucleoside phosphorylase, a nucleoside is prepared from the 1-phosphorylated saccharide derivative obtained and a base with improved stereoselectivity and a higher yield. This process is an anomer-selective process for preparing a 1-phosphorylated saccharide derivative and a nucleoside.
摘要翻译： 通过使1-磷酸化糖衍生物的异头混合物进行磷酸化和异构化同时结晶异构体之一以置换平衡来选择性地制备所需的异构体。 此外，使用核苷磷酰化酶的作用，由所得的1-磷酸化糖衍生物和具有改善的立体选择性和较高产率的碱制备核苷。 该方法是用于制备1-磷酸化糖衍生物和核苷的前体选择性方法。
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公开(公告)号：US20110288255A1
公开(公告)日：2011-11-24
申请号：US13197066
申请日：2011-08-03
申请人： Hiroko Shibamoto , Toshikazu Aikawa , Teruo Arii , Masanori Muramoto , Takeshi Fukuda , Kiyoshi Ito , Takeya Abe , Souichi Hazama
发明人： Hiroko Shibamoto , Toshikazu Aikawa , Teruo Arii , Masanori Muramoto , Takeshi Fukuda , Kiyoshi Ito , Takeya Abe , Souichi Hazama
CPC分类号： C12P13/00 , C07C231/06 , C08F220/56 , C12P13/02 , C07C233/09
摘要： A method for producing an amide compound from a nitrile compound in an aqueous medium in the presence of a catalyst having a nitrile hydratase activity wherein the concentration of benzene in the aqueous medium is 4.0 ppm or less and a method for producing an amide-based polymer excellent in quality from the amide compound. Also provided are a method for more efficiently producing an acrylamide with higher quality by a microbial catalyst containing a nitrile hydratase and the like and a method for producing an acrylamide-based polymer, which is excellent in hue, has a good balance between water solubility and high molecular weight and is excellent in quality.
摘要翻译： 在具有腈水合酶活性的催化剂存在下，在含水介质中由腈化合物制备酰胺化合物的方法，其中水介质中苯的浓度为4.0ppm或更低，以及制备酰胺基聚合物的方法 优异的酰胺化合物。 还提供了通过含有腈水合酶等的微生物催化剂更有效地制备具有更高质量的丙烯酰胺的方法和色调优异的丙烯酰胺类聚合物的制造方法，水溶性与 高分子量，质量优良。
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公开(公告)号：US07038039B2
公开(公告)日：2006-05-02
申请号：US09958305
申请日：2001-02-13
申请人： Hironori Komatsu , Hirokazu Awano , Nobuyuki Fukazawa , Kiyoshi Ito , Ichirou Ikeda , Tadashi Araki , Takeshi Nakamura , Tamotsu Asano , Junya Fujiwara , Tomoyuki Ando , Katsutoshi Tsuchiya , Kyoko Maruyama , Hideki Umetani , Takahiro Yamauchi , Hitoki Miyake
发明人： Hironori Komatsu , Hirokazu Awano , Nobuyuki Fukazawa , Kiyoshi Ito , Ichirou Ikeda , Tadashi Araki , Takeshi Nakamura , Tamotsu Asano , Junya Fujiwara , Tomoyuki Ando , Katsutoshi Tsuchiya , Kyoko Maruyama , Hideki Umetani , Takahiro Yamauchi , Hitoki Miyake
IPC分类号： A61K31/665 , A61K31/7024 , C07F9/6544
摘要： A desired isomer is selectively prepared by phosphorolyzing and isomerizing an anomer mixture of a 1-phosphorylated saccharide derivative while crystallizing one of the isomers to displace the equilibrium. Furthermore, using the action of a nucleoside phosphorylase, a nucleoside is prepared from the 1-phosphorylated saccharide derivative obtained and a base with improved stereoselectivity and a higher yield. This process is an anomer-selective process for preparing a 1-phosphorylated saccharide derivative and a nucleoside.
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公开(公告)号：US08717599B2
公开(公告)日：2014-05-06
申请号：US12989409
申请日：2009-06-18
申请人： Taketo Ochiai , Hirokazu Higuchi , Chihiro Hiranuma , Kiyoshi Ito
发明人： Taketo Ochiai , Hirokazu Higuchi , Chihiro Hiranuma , Kiyoshi Ito
CPC分类号： H04N1/00962 , G03G15/5075 , H04N1/00236 , H04N1/00938 , H04N2201/0041 , H04N2201/0049 , H04N2201/007 , H04N2201/0075
摘要： The present invention is applicable to a peripheral device which performs processing based on information from an information processing device. The peripheral device of present invention is characterized by a storage unit, which stores in it a program of controlling of designated processing, and stores in it data for controlling the peripheral device, and by a communication unit which sends the program stored in the storage unit to the information processing device, and by a control unit which controls operation of the peripheral device based on an instruction information written into the storage unit upon execution of the program on the information processing device.
摘要翻译： 本发明可应用于基于来自信息处理设备的信息执行处理的外围设备。 本发明的外围设备的特征在于存储单元，其中存储有指定处理的控制程序，并存储用于控制外围设备的数据，以及通过发送存储在存储单元中的程序的通信单元 信息处理装置，以及通过在信息处理装置上执行程序时，基于写入存储单元的指令信息来控制外围设备的操作的控制单元。
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公开(公告)号：US08496186B2
公开(公告)日：2013-07-30
申请号：US13011578
申请日：2011-01-21
申请人： Kiyoshi Ito
发明人： Kiyoshi Ito
IPC分类号： G06K19/06
CPC分类号： G06K19/06028 , G06K19/083 , G09F3/0288 , G09F3/0297 , G09F3/10
摘要： A shipping label includes a shipping label and an advertising label, and a tear-off tab is formed in the back liner sheet by a score line. After removing the tear-off tab and forming an exposed adhesive layer portion, the label part where the second barcode is printed is folded to the back side of the label to form a back-folded portion, which is held to the back side of the label by the exposed adhesive layer portion. The liner sheet portion contiguous to the tear-off tab is then removed, and the label is attached to the product. Because the second barcode is hidden on the back, only the first barcodes containing tracking information can be read, while the second barcode can be read as needed by unfolding the back-folded portion to the front.
摘要翻译： 运输标签包括运输标签和广告标签，并且通过刻痕线在背衬板中形成撕纸片。 在去除撕下突片并形成暴露的粘合剂层部分之后，将打印第二条形码的标签部分折叠到标签的背面，以形成背部折叠部分，该折叠部分保持在背面 通过暴露的粘合剂层部分标记。 然后移除与撕纸片相邻的衬垫片部分，并将标签贴在产品上。 由于第二条形码隐藏在背面，所以只能读取包含跟踪信息的第一个条形码，同时可以根据需要通过展开折叠后的前端部分来读取第二条形码。
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公开(公告)号：US20110038005A1
公开(公告)日：2011-02-17
申请号：US12989409
申请日：2009-06-18
申请人： Taketo Ochiai , Hirokazu Higuchi , Chihiro Hiranuma , Kiyoshi Ito
发明人： Taketo Ochiai , Hirokazu Higuchi , Chihiro Hiranuma , Kiyoshi Ito
IPC分类号： G06F3/12
CPC分类号： H04N1/00962 , G03G15/5075 , H04N1/00236 , H04N1/00938 , H04N2201/0041 , H04N2201/0049 , H04N2201/007 , H04N2201/0075
摘要： The present invention is applicable to a peripheral device which performs processing based on information from an information processing device. The peripheral device of present invention is characterized by a storage unit, which stores in it a program of controlling of designated processing, and stores in it data for controlling the peripheral device, and by a communication unit which sends the program stored in the storage unit to the information processing device, and by a control unit which controls operation of the peripheral device based on an instruction information written into the storage unit upon execution of the program on the information processing device.
摘要翻译： 本发明可应用于基于来自信息处理设备的信息执行处理的外围设备。 本发明的外围设备的特征在于存储单元，其中存储有指定处理的控制程序，并存储用于控制外围设备的数据，以及通过发送存储在存储单元中的程序的通信单元 信息处理装置，以及通过在信息处理装置上执行程序时，基于写入存储单元的指令信息来控制外围设备的操作的控制单元。
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10.发明申请CONTROL METHOD FOR A PRINT PROCESSING DEVICE, CONTROL METHOD FOR A RECEIPT PRINTING DEVICE, A PRINT PROCESSING DEVICE, A RECEIPT ISSUING SYSTEM, AND A PROGRAM 审中-公开打印处理装置的控制方法，接收打印装置的控制方法，打印处理装置，接收发行系统和程序公开(公告)号：US20100325050A1
公开(公告)日：2010-12-23
申请号：US12817894
申请日：2010-06-17
申请人： Kiyoshi Ito , Toshio Kuriyama , Akira Miyagawa
发明人： Kiyoshi Ito , Toshio Kuriyama , Akira Miyagawa
CPC分类号： B41M5/00
摘要： A method and system are provided for a receipt printing device that produces receipts. Encrypted data is necessary to produce the receipt to prevent forgery of the receipt. The encrypted data based on information, which can be transaction information, received from a POS terminal. The encrypted data will be printed on the receipt only when determined to be necessary.
摘要翻译： 提供了一种用于产生收据的收据打印设备的方法和系统。 加密数据是生成收据以防止伪造收据的必要条件。 基于从POS终端接收到的可以是交易信息的信息的加密数据。 只有在确定需要时，加密数据才会打印在收据上。
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