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公开(公告)号：US20190208998A1
公开(公告)日：2019-07-11
申请号：US16240032
申请日：2019-01-04
发明人： Jessica Powers , Jacob Caldwell , Sungmin R. Cho , Youseph Yazdi , Nicholas J. Durr , Pankaj J. Pasricha , Chad Weiler , Ashish Nimgaonkar
CPC分类号： A61B1/043 , A61B1/00096 , A61B1/00101 , A61B1/00137 , A61B1/00165 , A61B1/00177 , A61B1/00186 , A61B1/018 , A61B1/05 , A61B1/0646 , A61B1/0661 , A61B1/07 , A61B1/2736
摘要： Fluorescent imaging systems for performing an endoscopic procedure, such as a retrograde cholangiopancreatography (ERCP) procedure may include a first light source for emitting light in the visible spectrum, or light in the near infrared (NIR) spectrum, or both. A light source bandpass filter may block the emitted light in the visible spectrum, or in the NIR spectrum, or both. A first sensor may be capable of detecting the light in the visible spectrum, or the light in the NIR spectrum, or both. A sensor bandpass filter may block the detected light in the visible spectrum, or in the NIR spectrum, or both. The first or a second light source, or the first or a second sensor, or combinations thereof, may be removably disposed on a duodenoscope.
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公开(公告)号：US20160354509A1
公开(公告)日：2016-12-08
申请号：US15117715
申请日：2015-02-10
IPC分类号： A61L24/04
CPC分类号： A61L24/043 , A61K9/7007 , A61L24/06 , A61L24/08 , C08L33/02 , C08L5/08
摘要： Devices for and methods of treatment of metabolic syndromes are disclosed. Namely, the presently disclosed devices and methods are provided for affecting the function of the gastrointestinal endocrine system in key regions of the gut, thereby, producing therapeutic effects on obesity, diabetes and other metabolic syndromes. In some embodiments, the devices include multilayered bioadhesive patches delivered orally by dissolvable ingestible capsule, wherein various mechanisms are provided for anchoring the bioadhesive patches to the duodenal mucosa.
摘要翻译： 公开了代谢综合征的治疗方法和方法。 也就是说，提供了目前公开的装置和方法，用于影响胃肠内分泌系统在肠道关键区域的功能，从而产生对肥胖，糖尿病和其他代谢综合征的治疗作用。 在一些实施方案中，所述装置包括通过可溶解的可摄取胶囊口服递送的多层生物粘附性贴片，其中提供了用于将生物粘附性贴片锚定到十二指肠粘膜的各种机制。
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公开(公告)号：US11627870B2
公开(公告)日：2023-04-18
申请号：US16240032
申请日：2019-01-04
发明人： Jessica Powers , Jacob Caldwell , Sungmin R. Cho , Youseph Yazdi , Nicholas J. Durr , Pankaj J. Pasricha , Chad Weiler , Ashish Nimgaonkar
摘要： Fluorescent imaging systems for performing an endoscopic procedure, such as a retrograde cholangiopancreatography (ERCP) procedure may include a first light source for emitting light in the visible spectrum, or light in the near infrared (NIR) spectrum, or both. A light source bandpass filter may block the emitted light in the visible spectrum, or in the NIR spectrum, or both. A first sensor may be capable of detecting the light in the visible spectrum, or the light in the NIR spectrum, or both. A sensor bandpass filter may block the detected light in the visible spectrum, or in the NIR spectrum, or both. The first or a second light source, or the first or a second sensor, or combinations thereof, may be removably disposed on a duodenoscope.
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公开(公告)号：US11090354B2
公开(公告)日：2021-08-17
申请号：US15750460
申请日：2016-08-05
发明人： Thomas Jozefiak , Michael Parlato , Pratik Patel , Kevin Colbert , Ashish Nimgaonkar , Pankaj Pasricha
IPC分类号： A61K38/00 , A61K38/02 , A61K31/722 , A61K31/79 , A61K47/32 , A61K9/00 , A61K9/08 , A61K47/36 , A61K47/38 , A61K47/34 , A61K9/16 , A61K9/20 , A61K9/50 , A61K47/26 , A61K9/06 , A61K9/48
摘要： The present invention provides compositions and methods for treatment of metabolic syndromes. Namely, the presently disclosed compositions and methods are provided for affecting the function of the gastrointestinal endocrine system in key regions of the gut, thereby, producing therapeutic effects on obesity, diabetes and other metabolic disorders. The compositions include components for forming luminal barriers within the gastrointestinal tract of a subject where the barrier is created in-situ via interaction of resident mucin with the mucin-interacting agent.
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公开(公告)号：US20180236127A1
公开(公告)日：2018-08-23
申请号：US15962911
申请日：2018-04-25
CPC分类号： A61L24/043 , A61K9/7007 , A61L24/06 , A61L24/08 , C08L33/02 , C08L5/08
摘要： Devices for and methods of treatment of metabolic syndromes are disclosed. Namely, the presently disclosed devices and methods are provided for affecting the function of the gastrointestinal endocrine system in key regions of the gut, thereby, producing therapeutic effects on obesity, diabetes and other metabolic syndromes. In some embodiments, the devices include multilayered bioadhesive patches delivered orally by dissolvable ingestible capsule, wherein various mechanisms are provided for anchoring the bioadhesive patches to the duodenal mucosa.
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公开(公告)号：US20170361074A1
公开(公告)日：2017-12-21
申请号：US15532910
申请日：2015-12-07
CPC分类号： A61M27/002 , A61M1/0066 , A61M1/1003 , A61M1/1037 , A61M1/122 , A61M25/0075 , A61M2025/0078 , A61M2202/0401
摘要： An implantable, body-driven shunt pump includes a pump body defining a fluid inlet, a fluid outlet and a fluid chamber therebetween; an inlet valve arranged in the fluid inlet, the inlet valve being a one-way valve arranged such that it is operable to allow fluid flow into the fluid chamber and to prevent fluid flow out of the fluid chamber; and an outlet valve arranged in the fluid outlet, the outlet valve being a one-way valve arranged such that it is operable to allow fluid flow out of the fluid chamber and to prevent fluid flow into the fluid chamber. The pump body includes an expandable and contractible component in a portion of the pump body that defines the fluid chamber such that the fluid chamber changes volume in response to a change in pressure of fluid in the fluid chamber.
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公开(公告)号：US20230210353A1
公开(公告)日：2023-07-06
申请号：US18117775
申请日：2023-03-06
发明人： Jessica Powers , Jacob Caldwell , Sungmin R. Cho , Youseph Yazdi , Nicholas J. Durr , Pankaj J. Pasricha , Chad Weiler , Ashish Nimgaonkar
CPC分类号： A61B1/043 , A61B1/018 , A61B1/00137 , A61B1/2736 , A61B1/00177 , A61B1/00101 , A61B1/00096 , A61B1/00186 , A61B1/0646 , A61B1/00165 , A61B1/05
摘要： Fluorescent imaging systems for performing an endoscopic procedure, such as a retrograde cholangiopancreatography (ERCP) procedure may include a first light source for emitting light in the visible spectrum, or light in the near infrared (NIR) spectrum, or both. A light source bandpass filter may block the emitted light in the visible spectrum, or in the NIR spectrum, or both. A first sensor may be capable of detecting the light in the visible spectrum, or the light in the NIR spectrum, or both. A sensor bandpass filter may block the detected light in the visible spectrum, or in the NIR spectrum, or both. The first or a second light source, or the first or a second sensor, or combinations thereof, may be removably disposed on a duodenoscope.
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公开(公告)号：US10994107B2
公开(公告)日：2021-05-04
申请号：US15532910
申请日：2015-12-07
IPC分类号： A61M27/00 , A61M1/00 , A61M25/00 , A61M60/268 , A61M60/882
摘要： An implantable, body-driven shunt pump includes a pump body defining a fluid inlet, a fluid outlet and a fluid chamber therebetween; an inlet valve arranged in the fluid inlet, the inlet valve being a one-way valve arranged such that it is operable to allow fluid flow into the fluid chamber and to prevent fluid flow out of the fluid chamber; and an outlet valve arranged in the fluid outlet, the outlet valve being a one-way valve arranged such that it is operable to allow fluid flow out of the fluid chamber and to prevent fluid flow into the fluid chamber. The pump body includes an expandable and contractible component in a portion of the pump body that defines the fluid chamber such that the fluid chamber changes volume in response to a change in pressure of fluid in the fluid chamber.
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公开(公告)号：US20180228863A1
公开(公告)日：2018-08-16
申请号：US15750460
申请日：2016-08-05
发明人： Thomas Jozefiak , Michael Parlato , Pratik Patel , Kevin Colbert , Ashish Nimgaonkar , Pankaj Pasricha
CPC分类号： A61K38/02 , A61K9/0095 , A61K9/06 , A61K9/08 , A61K9/16 , A61K9/20 , A61K9/48 , A61K9/50 , A61K31/722 , A61K31/79 , A61K47/26 , A61K47/32 , A61K47/34 , A61K47/36 , A61K47/38
摘要： The present invention provides compositions and methods for treatment of metabolic syndromes. Namely, the presently disclosed compositions and methods are provided for affecting the function of the gastrointestinal endocrine system in key regions of the gut, thereby, producing therapeutic effects on obesity, diabetes and other metabolic disorders. The compositions include components for forming luminal barriers within the gastrointestinal tract of a subject where the barrier is created in-situ via interaction of resident mucin with the mucin-interacting agent.
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