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公开(公告)号：US10925823B2
公开(公告)日：2021-02-23
申请号：US16412745
申请日：2019-05-15
发明人： James Robert Schwartz , Leo Timothy Laughlin, II , Lijuan Li , Junjun Chen , Kathleen Marie Kerr
摘要： The present invention discloses to a personal care composition having a polyvalent metal salt of pyrithione; a 2-pyridinol-N-oxide material; and a zinc containing layered material; wherein the ratio of a:b is from about 0.5 to about 1.5; the ratio of b:c is about 0.2 to about 1.0; and the ratio of a:c is about 0.2 to about 1.0 and wherein there is a synergistic antioxidant activity.
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公开(公告)号：US09964472B2
公开(公告)日：2018-05-08
申请号：US15197505
申请日：2016-06-29
发明人： Sancai Xie , John Christian Haught , Cheryl Sue Tansky , Thomas Glenn Huggins, Jr. , Donald James White, Jr. , Lijuan Li , Malgorzata Klukowska , Angela Marie Fieno , Deepa Ashok Khambe
CPC分类号： G01N1/28 , A46B15/00 , A46B2200/108 , A61B10/0051 , A61B10/02 , A61B2010/0216 , A61B2010/0225 , A61C19/00 , A61Q11/00 , G01N2800/18
摘要： One or more methods for sampling gingival metabolites and biomarkers.
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公开(公告)号：US20170135932A1
公开(公告)日：2017-05-18
申请号：US15165440
申请日：2016-05-26
发明人： James Robert Schwartz , James Patrick Henry , Michael Joseph Flagler , Steven Hardy Page , Kathleen Marie Kerr , Kenneth Robert Wehmeyer , Lijuan Li , Nancy Lee Redman-Furey
CPC分类号： A61K8/58 , A61K8/27 , A61K2800/40 , A61K2800/522 , A61Q5/002 , A61Q5/006 , A61Q5/02
摘要： A method of improving the health of hair emerging from a scalp comprising application of a composition to reduce oxidative stress in the scalp causing reduced oxidative stress in pre-emergent hair resulting in healthier emergent hair having reduced water absorption and reduced surface energy
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公开(公告)号：US20200316141A1
公开(公告)日：2020-10-08
申请号：US16838046
申请日：2020-04-02
IPC分类号： A61K35/742 , A61K35/745 , A61K35/747 , A61K36/06 , A61K38/43
摘要： Described herein is a composition containing probiotic bacteria and a fermentate that can increase IPA production. The composition comprises one or more bacteria having a nucleic acid sequence with at least 80% homology to the nucleic acid sequence of SEQ ID NO: 1, a fermentate comprising soy flour, a yeast, and a proteolytic enzyme, and an excipient, carrier, and/or diluent. The composition can promote brain health and/or nervous system function.
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公开(公告)号：US11771765B2
公开(公告)日：2023-10-03
申请号：US16913191
申请日：2020-06-26
IPC分类号： A61K41/00 , A61K31/44 , A61K31/4412 , A61K31/444
CPC分类号： A61K41/0057 , A61K31/44 , A61K31/444 , A61K31/4412
摘要： The present invention is directed to a method of treating skin and scalp comprising applying on the scalp or skin a composition comprising a scalp care active selected from the group consisting of 2-Pyridinol-N-oxide, a pyrithione or a polyvalent metal salt of pyrithione, one or more iron chelator having an A log P value of greater than or equal to 0.4 and mixtures therein; exposing the scalp and skin to electromagnetic radiation having wavelength from about 350 nm to about 500 nm and power from about about 0.1 mWatts/cm2 to about 1000 mWatts/cm2 and for a time period from about 2 seconds to about 5 minutes; wherein the antimicrobial treatment results in reduction of fungal growth as measured by the Fungal Growth Sensitivity Test of at least 50% compared to the dark sample.
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6.发明申请公开(公告)号：US20200316023A1
公开(公告)日：2020-10-08
申请号：US16838045
申请日：2020-04-02
发明人： Arvind Venkataraman , Chelsay Lynn Brewster , Kimberly Conner Kozak , Lijuan Li , Jason Allen Stamper
IPC分类号： A61K31/405 , C12P13/00 , A61K35/747 , A61K35/745 , A61K35/744 , A61K35/74
摘要： Described herein is a method for producing indole-3-propionic acid and other indole derivatives via bacterial fermentation and compositions of the same. The method comprises adding bacteria having a nucleic acid sequence with at least 80% homology to the nucleic acid sequence of SEQ ID NO: 1 to a liquid fermentation medium; fermenting at about 36° C. under anaerobic conditions; adding a dehydrating agent; and dehydrating to obtain a fermentate powder comprising indole-3-propionic acid and other indole derivatives.
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公开(公告)号：US20190350831A1
公开(公告)日：2019-11-21
申请号：US16412745
申请日：2019-05-15
发明人： James Robert Schwartz , Leo Timothy Laughlin, II , Lijuan Li , Junjun Chen , Kathleen Marie Kerr
摘要： The present invention discloses to a personal care composition having a polyvalent metal salt of pyrithione; a 2-pyridinol-N-oxide material; and a zinc containing layered material; wherein the ratio of a:b is from about 0.5 to about 1.5; the ratio of b:c is about 0.2 to about 1.0; and the ratio of a:c is about 0.2 to about 1.0 and wherein there is a synergistic antioxidant activity.
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公开(公告)号：US20160346184A1
公开(公告)日：2016-12-01
申请号：US15165418
申请日：2016-05-26
发明人： James Robert Schwartz , James Patrick Henry , Kathleen Marie Kerr , Kenneth Robert Wehmeyer , Lijuan Li , Haruko Mizoguchi
CPC分类号： A61K8/58 , A61K8/27 , A61K2800/522 , A61K2800/58 , A61Q5/002 , A61Q5/006 , A61Q5/02 , A61Q5/12
摘要： A method of improving the health of hair emerging from a scalp comprising a reduction of oxidative stress in the scalp by application of a composition resulting in reduction in oxidative stress in pre-emergent hair as demonstrated by reduced oxidative stress in emergent hair.
摘要翻译： 一种改善从头皮出现的头发健康的方法，其包括通过应用组合物降低头皮中的氧化应激，导致在出生前毛发中减少氧化应激，如通过在紧急毛发中减少的氧化应激所证明的。
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