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    Light augmented treatment method
    1.
    发明授权
    Light augmented treatment method 有权

    公开(公告)号：US11771765B2

    公开(公告)日：2023-10-03

    申请号：US16913191

    申请日：2020-06-26

    申请人： The Procter & Gamble Company

    发明人： Charles Winston Saunders ,  Robert Scott Youngquist ,  Lijuan Li ,  Justin Angelo Caserta

    IPC分类号： A61K41/00 ,  A61K31/44 ,  A61K31/4412 ,  A61K31/444

    CPC分类号： A61K41/0057 ,  A61K31/44 ,  A61K31/444 ,  A61K31/4412

    摘要： The present invention is directed to a method of treating skin and scalp comprising applying on the scalp or skin a composition comprising a scalp care active selected from the group consisting of 2-Pyridinol-N-oxide, a pyrithione or a polyvalent metal salt of pyrithione, one or more iron chelator having an A log P value of greater than or equal to 0.4 and mixtures therein; exposing the scalp and skin to electromagnetic radiation having wavelength from about 350 nm to about 500 nm and power from about about 0.1 mWatts/cm2 to about 1000 mWatts/cm2 and for a time period from about 2 seconds to about 5 minutes; wherein the antimicrobial treatment results in reduction of fungal growth as measured by the Fungal Growth Sensitivity Test of at least 50% compared to the dark sample.

    Systems for identifying cosmetic agents for skin care compositions
    5.
    发明授权
    Systems for identifying cosmetic agents for skin care compositions 有权
    用于鉴定护肤组合物的化妆品的系统

    公开(公告)号：US09434993B2

    公开(公告)日：2016-09-06

    申请号：US14749717

    申请日：2015-06-25

    申请人： The Procter & Gamble Company

    发明人： Robert Lloyd Binder ,  Robert Scott Youngquist ,  Jun Xu ,  Kenton Duane Juhlin ,  Rosemarie Osborne ,  Scott Michael Hartman

    IPC分类号： C40B60/12 ,  C12Q1/68 ,  G06F19/18 ,  G06F19/20 ,  G06F19/28

    CPC分类号： C12Q1/6883 ,  C12Q2600/148 ,  C12Q2600/158 ,  G06F19/18 ,  G06F19/20 ,  G06F19/28

    摘要： A system for identifying connections between a cosmetic agent and at least one gene associated with a skin aging condition. The system includes a computer readable medium having stored thereon a plurality of instances and a skin aging gene expression signature. Each instance comprises an ordered list of identifiers representing a plurality of differentially expressed genes generated as a result of contact between the cosmetic agent and a human fibroblast cell or a human keratinocyte cell. The computing device includes computer-readable instructions for accessing the plurality of instances and the skin aging gene expression signature stored on the computer readable medium, comparing each of the instances to the skin aging gene expression signature, and assigning a connectivity score to each of the instances based on the comparison.

    摘要翻译： 一种用于鉴定美容剂与至少一种与皮肤老化状况相关的基因之间的连接的系统。 该系统包括其上存储有多个实例和皮肤老化基因表达特征的计算机可读介质。 每个实例包括代表由化妆剂与人成纤维细胞或人角质形成细胞之间接触而产生的多个差异表达基因的标识符的有序列表。 计算设备包括用于访问存储在计算机可读介质上的多个实例和皮肤老化基因表达签名的计算机可读指令，将每个实例与皮肤老化基因表达签名进行比较，并将连接性分数分配给每个 基于比较的实例。

    Systems For Identifying Cosmetic Agents For Skin Care Compositions
    6.
    发明申请
    Systems For Identifying Cosmetic Agents For Skin Care Compositions 审中-公开
    用于鉴定护肤组合物的化妆品的系统

    公开(公告)号：US20150292017A1

    公开(公告)日：2015-10-15

    申请号：US14749717

    申请日：2015-06-25

    申请人： The Procter & Gamble Company

    发明人： Robert Lloyd Binder ,  Robert Scott Youngquist ,  Jun XU ,  Kenton Duane JUHLIN ,  Rosemarie OSBORNE ,  Scott Michael HARTMAN

    IPC分类号： C12Q1/68 ,  G06F19/28 ,  G06F19/18 ,  G06F19/20

    CPC分类号： C12Q1/6883 ,  C12Q2600/148 ,  C12Q2600/158 ,  G06F19/18 ,  G06F19/20 ,  G06F19/28

    摘要： A system for identifying connections between a cosmetic agent and at least one gene associated with a skin aging condition. The system includes a computer readable medium having stored thereon a plurality of instances and a skin aging gene expression signature. Each instance comprises an ordered list of identifiers representing a plurality of differentially expressed genes generated as a result of contact between the cosmetic agent and a human fibroblast cell or a human keratinocyte cell. The computing device includes computer-readable instructions for accessing the plurality of instances and the skin aging gene expression signature stored on the computer readable medium, comparing each of the instances to the skin aging gene expression signature, and assigning a connectivity score to each of the instances based on the comparison.

    摘要翻译： 一种用于鉴定美容剂与至少一种与皮肤老化状况相关的基因之间的连接的系统。 该系统包括其上存储有多个实例和皮肤老化基因表达特征的计算机可读介质。 每个实例包括代表由化妆剂与人成纤维细胞或人角质形成细胞之间接触而产生的多个差异表达基因的标识符的有序列表。 计算设备包括用于访问存储在计算机可读介质上的多个实例和皮肤老化基因表达签名的计算机可读指令，将每个实例与皮肤老化基因表达签名进行比较，并将连接性分数分配给每个 基于比较的实例。