公开(公告)号：US20220403364A1

公开(公告)日：2022-12-22

申请号：US17608018

申请日：2020-04-28

申请人： The Trustees of Princeton University

发明人： Sujit Datta ,  Tapomoy Bhattacharjee

IPC分类号： C12N11/04 ,  C12N1/04 ,  C12M3/06 ,  C12M1/12 ,  C12M1/34 ,  C12N1/20

摘要： Disclosed is a 3D porous medium and a method of manufacture. The 3D porous medium includes (i) a support structure of transparent hydrogel particles or emulsion droplets, (ii) bacterial nutrient in open volumes between the transparent hydrogel particles, as well as within micropores in the transparent hydrogel particles, and (iii) bacterial cells within the open volumes in the support structure.

公开(公告)号：US20240024829A1

公开(公告)日：2024-01-25

申请号：US18221086

申请日：2023-07-12

申请人： The Trustees of Princeton University

发明人： Sujit Datta ,  Christopher Browne ,  Richard Huang ,  Callie Zheng

IPC分类号： B01F23/40 ,  C08J3/09 ,  B01J19/30 ,  B01J19/00 ,  B01F21/00 ,  B01F23/451 ,  B01F35/221 ,  B01F35/21 ,  B01F35/71 ,  G01N21/64

CPC分类号： B01F23/405 ,  C08J3/095 ,  B01J19/30 ,  B01J19/0006 ,  B01F21/02 ,  B01F23/451 ,  B01F35/2213 ,  B01F35/2217 ,  B01F35/2136 ,  B01F35/7176 ,  G01N21/6428 ,  C08J2333/26 ,  B01J2219/00162 ,  B01J2219/00164 ,  B01J2219/00234 ,  B01F2101/2805

摘要： Disclosed are techniques to mimic turbulent-enhanced reactivity under confinement by the addition of dilute high molecular weight polymers. Micro-scale imaging within a transparent porous medium reveals an elastic instability (EI), which drives chaotic fluctuations that stretch and fold solute blobs exponentially in time analogous to turbulent Batchelor mixing, despite the low Re. A reduction in the required mixing length can be observed, suggesting a cooperation between the elastic instability and the dispersion inherent to the disordered 3D porous media—which can be modeled as additive independent mixing rates, representing a dramatic conceptual simplification. The disclosed enhanced transport of solutes circumvents the traditional trade-off between throughput and reactor length, allowing a simultaneous large reduction in length and increases in throughput. Elastic flow instabilities can provide turbulent-like enhancements in chemical reaction rates, which can operate cooperatively with dispersive mixing in industrially relevant geometries.