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1.发明授权公开(公告)号：US08824755B2
公开(公告)日：2014-09-02
申请号：US13368395
申请日：2012-02-08
CPC分类号： A61B6/032 , A61B6/037 , A61B6/12 , A61B6/4014 , A61B6/4435 , A61B6/481 , A61B6/504 , A61B6/5229 , G06F19/00 , G06T7/12 , G06T7/344 , G06T17/00 , G06T2207/10072 , G06T2207/30101 , G06T2207/30172
摘要： A method and a computer system are disclosed for automatically generating a statistical vascular model of a patient group. In at least one embodiment, the method includes collecting determining patient-related vascular coordinates models from a multiplicity of vascular landmark coordinates of vascular landmarks, centerline coordinates on vessel centerlines and vessel contour coordinates on vessel contour edge profiles; determining body landmark coordinates of body landmarks; registering the vessel-related coordinates to patient-related registered vascular coordinates models; merging patient-related vascular parameter models to form at least one statistical vascular parameter model; determining the statistical parameters thereof; and saving and/or outputting the at least one statistical vascular parameter model.
摘要翻译： 公开了一种用于自动产生患者组的统计血管模型的方法和计算机系统。 在至少一个实施例中，该方法包括从血管标志的多个血管标记坐标，血管中心线上的中心线坐标和血管轮廓边缘轮廓上的血管轮廓坐标收集确定与患者相关的血管坐标模型; 确定身体地标的身体地标坐标; 将与血管相关的坐标注册到患者相关的血管坐标模型; 合并患者相关的血管参数模型以形成至少一个统计血管参数模型; 确定其统计参数; 以及保存和/或输出所述至少一个统计血管参数模型。
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2.发明申请公开(公告)号：US20120201442A1
公开(公告)日：2012-08-09
申请号：US13368395
申请日：2012-02-08
IPC分类号： G06K9/00
CPC分类号： A61B6/032 , A61B6/037 , A61B6/12 , A61B6/4014 , A61B6/4435 , A61B6/481 , A61B6/504 , A61B6/5229 , G06F19/00 , G06T7/12 , G06T7/344 , G06T17/00 , G06T2207/10072 , G06T2207/30101 , G06T2207/30172
摘要： A method and a computer system are disclosed for automatically generating a statistical vascular model of a patient group. In at least one embodiment, the method includes collecting specifying patient-related vascular coordinates models from a multiplicity of vascular landmark coordinates of vascular landmarks, centerline coordinates on vessel centerlines and vessel contour coordinates on vessel contour edge profiles; specifying body landmark coordinates of body landmarks; registering the vessel-related coordinates to patient-related registered vascular coordinates models; merging patient-related vascular parameter models to form at least one statistical vascular parameter model; specifying the statistical parameters thereof; and saving and/or outputting the at least one statistical vascular parameter model.
摘要翻译： 公开了一种用于自动产生患者组的统计血管模型的方法和计算机系统。 在至少一个实施例中，该方法包括从血管标志的多个血管标记坐标，血管中心线上的中心线坐标和血管轮廓边缘轮廓上的血管轮廓坐标收集指定与患者相关的血管坐标模型; 指定身体地标的身体地标坐标; 将与血管相关的坐标注册到患者相关的血管坐标模型; 合并患者相关的血管参数模型以形成至少一个统计血管参数模型; 指定其统计参数; 以及保存和/或输出所述至少一个统计血管参数模型。
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3.发明授权公开(公告)号：US08712132B2
公开(公告)日：2014-04-29
申请号：US13092999
申请日：2011-04-25
IPC分类号： G06K9/00
CPC分类号： A61B6/504 , A61B5/055 , A61B6/03 , A61B6/4441 , A61B6/481 , A61B6/487 , A61B6/5235 , A61B6/5247 , G06F19/00 , G06T7/12 , G06T7/149 , G06T7/33 , G06T2207/10081 , G06T2207/30101 , G16H50/20 , G16H50/50
摘要： A method and a computer system are disclosed for automatic vectorization of the profile of a vessel tree and at least one of its properties on the basis of tomographic images of an examined patient. In at least one embodiment, using previously established location probabilities of landmarks in the vessel tree, there is an automatic determination of a plurality of distinctive landmarks in the current tomographic image data record of the patient, a registration of the current tomographic image data record to the statistical vessel model, an automatic determination of previously unidentified landmarks in the registered tomographic image data record using characteristic identification features of the previously unidentified landmarks from the statistical vessel model and the statistical location probability thereof, and a determination of at least one current vessel model using the identified landmarks and at least one vessel property at and/or between the identified landmarks.
摘要翻译： 公开了一种方法和计算机系统，用于基于检查的患者的断层图像自动矢量化血管树的轮廓和其属性中的至少一个。 在至少一个实施例中，使用先前建立的血管树中的地标的位置概率，存在对患者的当前断层图像数据记录中的多个独特地标的自动确定，将当前断层图像数据记录登记到 统计血管模型，使用来自统计血管模型的先前未识别的地标的特征识别特征及其统计位置概率来自动确定登记的断层图像数据记录中的先前未识别的地标，以及确定至少一个当前血管模型 在所识别的地标之间和/或之间使用所识别的地标和至少一个船只属性。
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4.发明申请公开(公告)号：US20110262020A1
公开(公告)日：2011-10-27
申请号：US13092999
申请日：2011-04-25
IPC分类号： G06K9/00
CPC分类号： A61B6/504 , A61B5/055 , A61B6/03 , A61B6/4441 , A61B6/481 , A61B6/487 , A61B6/5235 , A61B6/5247 , G06F19/00 , G06T7/12 , G06T7/149 , G06T7/33 , G06T2207/10081 , G06T2207/30101 , G16H50/20 , G16H50/50
摘要： A method and a computer system are disclosed for automatic vectorization of the profile of a vessel tree and at least one of its properties on the basis of tomographic images of an examined patient. In at least one embodiment, using previously established location probabilities of landmarks in the vessel tree, there is an automatic determination of a plurality of distinctive landmarks in the current tomographic image data record of the patient, a registration of the current tomographic image data record to the statistical vessel model, an automatic determination of previously unidentified landmarks in the registered tomographic image data record using characteristic identification features of the previously unidentified landmarks from the statistical vessel model and the statistical location probability thereof, and a determination of at least one current vessel model using the identified landmarks and at least one vessel property at and/or between the identified landmarks.
摘要翻译： 公开了一种方法和计算机系统，用于基于检查的患者的断层图像自动矢量化血管树的轮廓和其属性中的至少一个。 在至少一个实施例中，使用先前建立的血管树中的地标的位置概率，存在对患者的当前断层图像数据记录中的多个独特地标的自动确定，将当前断层图像数据记录登记到 统计血管模型，使用来自统计血管模型的先前未识别的地标的特征识别特征及其统计位置概率来自动确定登记的断层图像数据记录中的先前未识别的地标，以及确定至少一个当前血管模型 在所识别的地标之间和/或之间使用所识别的地标和至少一个船只属性。
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公开(公告)号：US09791531B2
公开(公告)日：2017-10-17
申请号：US14231118
申请日：2014-03-31
申请人： Thomas Beck , Rainer Schneider
发明人： Thomas Beck , Rainer Schneider
CPC分类号： G01R33/543 , G01R33/243 , G01R33/246 , G01R33/583
摘要： A method for establishing a magnetic resonance system actuation sequence is described. A first number of field distribution maps are acquired for slices of the measurement region, and a radiofrequency pulse train is established on the basis thereof for the magnetic resonance system actuation sequence. This acquisition of the first number of field distribution maps may be brought about on the basis of an acquisition scheme. A reduced number of field distribution representation maps are established on the basis of the acquired field distribution maps, which field distribution representation maps represent the first number of acquired field distribution maps in accordance with a predetermined optimization criterion, and the radiofrequency pulse train is established on the basis of the field distribution representation maps.
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6.发明授权Method and branching determination device for determining a branching point within a hollow organ 有权用于确定中空器官内的分支点的方法和分支确定装置公开(公告)号：US09109391B2
公开(公告)日：2015-08-18
申请号：US12693556
申请日：2010-01-26
申请人： Thomas Beck , Christina Biermann
发明人： Thomas Beck , Christina Biermann
CPC分类号： E06B5/161 , A61B6/00 , E06B3/56 , E06B2003/2631 , E06B2003/7078 , G06K9/4638 , G06K9/62 , G06K2209/055 , G06T7/11 , G06T7/12 , G06T7/136 , G06T7/187 , G06T7/33 , G06T2207/30101
摘要： A method is disclosed for determining a branching point within a hollow organ in image data representing the spatial structure thereof. In at least one embodiment, the method includes setting a start point within the hollow organ; determining at least one local threshold which corresponds to the presence of a wall of the hollow organ; carrying out a region growing method using the threshold; analyzing the connectivity of a number of outer growth layers; and localizing a branching on the basis of the connectivity analysis. Moreover, at least one embodiment of the invention relates to a correspondingly designed branching determination unit.
摘要翻译： 公开了一种用于在表示其空间结构的图像数据中确定中空器官内的分支点的方法。 在至少一个实施例中，该方法包括设置中空器官内的起始点; 确定对应于所述中空器官的壁的存在的至少一个局部阈值; 使用阈值进行区域增长方法; 分析多个外生长层的连通性; 并在连通性分析的基础上本地化分支。 此外，本发明的至少一个实施例涉及相应设计的分支确定单元。
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公开(公告)号：US08618439B2
公开(公告)日：2013-12-31
申请号：US13397057
申请日：2012-02-15
申请人： Thomas Beck , Nigel-Philip Cox , Silke Settegast
发明人： Thomas Beck , Nigel-Philip Cox , Silke Settegast
CPC分类号： B23K15/085 , B23K26/384 , B23K26/389 , B23K2101/001 , F01D5/186 , F05D2230/13 , Y02T50/67 , Y02T50/676 , Y10T29/49341
摘要： There are a multiplicity of methods of making through-holes. In particular in the production of a multiplicity of film-cooling holes, as in gas turbine blades or combustion chamber elements, small time advantages are also important when making a hole. The method according to the invention, to make the hole close to the final contour in each case in sections in a top and a bottom region in order to then produce the final contour with other laser parameters, achieves time advantages.
摘要翻译： 有多种形成通孔的方法。 特别是在制造多个薄膜冷却孔时，如在燃气轮机叶片或燃烧室元件中，小的时间优点在制造孔时也是重要的。 根据本发明的方法，为了使其在顶部和底部区域中的每一种情况下，使得孔接近于最终轮廓，以便随后用其他激光参数产生最终轮廓，这实现了时间优点。
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8.发明申请公开(公告)号：US20130012438A1
公开(公告)日：2013-01-10
申请号：US13458086
申请日：2012-04-27
申请人： Henry Blair , Thomas Beck , Robert Charles Ladner
发明人： Henry Blair , Thomas Beck , Robert Charles Ladner
CPC分类号： A61K38/55 , A61K31/195 , A61K38/57 , A61K45/06 , A61K2300/00
摘要： Methods, kits and compositions are described that include a non-naturally occurring kallikrein inhibitor and an anti-thrombolytic agent, e.g., an anti-fibrinolytic agent, for preventing or reducing blood loss and/or ischemia, e.g., ischemia associated with perioperative blood loss and cerebral ischemia, the onset of systemic inflammatory response, and/or reperfusion injury, e.g., reperfusion injury associated with cerebral ischemia or a focal brain ischemia, e.g., in patients subjected to invasive surgical procedures, especially procedures requiring cardiopulmonary bypass.
摘要翻译： 描述了包括非天然存在的激肽释放酶抑制剂和抗血栓溶解剂（例如抗纤维蛋白溶解剂）的方法，试剂盒和组合物，用于预防或减少失血和/或缺血，例如与围手术期失血相关的缺血 脑缺血，全身炎症反应发作和/或再灌注损伤，例如与脑缺血或局灶性脑缺血相关的再灌注损伤，例如在经历侵入性外科手术的患者中，特别是需要体外循环的手术。
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公开(公告)号：US08237082B2
公开(公告)日：2012-08-07
申请号：US12223204
申请日：2007-01-05
申请人： Thomas Beck , Silke Settegast
发明人： Thomas Beck , Silke Settegast
IPC分类号： B23K26/38
CPC分类号： B23K26/0648 , B23K26/0622 , B23K26/064 , B23K26/0665 , B23K26/389
摘要： There is described a method for producing a hole using e.g. a lasers, wherein short laser pulse durations are used. The laser pulse durations are varied, short laser pulse durations being utilized only in the area to be removed in which an influence on the penetration behavior and discharge behavior is noticeable while longer pulse durations of >0.4 ms are used. This is the case for the inner surface of a diffuser of a hole, for example, which can be produced very accurately by means of short laser pulse durations.
摘要翻译： 描述了使用例如制造孔的方法。 激光器，其中使用短激光脉冲持续时间。 激光脉冲持续时间是变化的，短激光脉冲持续时间仅在要去除的区域中被使用，其中在使用> 0.4ms的较长脉冲持续时间时，对穿透行为和放电行为的影响是显着的。 这是例如孔的扩散器的内表面的情况，例如，可以通过短的激光脉冲持续时间非常精确地制造。
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公开(公告)号：US08188045B2
公开(公告)日：2012-05-29
申请号：US11804388
申请日：2007-05-18
申请人： Henry Blair , Thomas Beck , Robert C. Ladner
发明人： Henry Blair , Thomas Beck , Robert C. Ladner
CPC分类号： A61K38/55 , A61K31/195 , A61K38/57 , A61K45/06 , A61K2300/00
摘要： Methods, kits and compositions are described that include a non-naturally occurring kallikrein inhibitor and an anti-thrombolytic agent, e.g., an anti-fibrinolytic agent, for preventing or reducing blood loss and/or ischemia, e.g., ischemia associated with perioperative blood loss and cerebral ischemia, the onset of systemic inflammatory response, and/or reperfusion injury, e.g., reperfusion injury associated with cerebral ischemia or a focal brain ischemia, e.g., in patients subjected to invasive surgical procedures, especially procedures requiring cardiopulmonary bypass.
摘要翻译： 描述了包括非天然存在的激肽释放酶抑制剂和抗血栓溶解剂（例如抗纤维蛋白溶解剂）的方法，试剂盒和组合物，用于预防或减少失血和/或缺血，例如与围手术期失血相关的缺血 脑缺血，全身炎症反应发作和/或再灌注损伤，例如与脑缺血或局灶性脑缺血相关的再灌注损伤，例如在经历侵入性外科手术的患者中，特别是需要体外循环的手术。
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