摘要:
A system, method and apparatus for performing a renal replacement therapy is provided. In one embodiment, two small high flux dialyzers are connected in series. A restriction is placed between the two dialyzers in the dialysate flow path. The restriction is variable and adjustable in one preferred embodiment. The restriction builds a positive pressure in the venous dialyzer, causing a high degree of intentional backfiltration. That backfiltration causes a significant flow of dialysate through the high flux venous membrane directly into the patient's blood. That backfiltered solution is subsequently ultrafiltered from the patient from the arterial dialyzer. The diffusion of dialysate into the venous filter and removal of dialysate from the arterial dialyzer causes a convective transport of toxins from the patient. Additionally, the dialysate that does not diffuse directly into the patient but instead flows across the membranes of both dialyzers provides a diffusive clearance of waste products.
摘要:
A dialysis system includes an extracorporeal circuit including a dialyzer; a dialysis fluid circuit including a first balance chamber, a second balance chamber, a fresh dialysis fluid pump in fluid communication with first and second fresh compartments of the first and second balance chambers, respectively, the first and second fresh compartments in fluid communication with a fresh dialysate fluid inlet of the dialyzer, and a spent dialysis fluid pump in fluid communication with first and second spent compartments of the first and second balance chambers, respectively, the spent dialysis fluid pump also in fluid communication with a spent dialysis fluid outlet of the dialyzer; and wherein the system is configured to run a priming sequence that uses (i) at least one of the fresh and spent dialysis fluid pumps and the first and second balance chambers to pump dialysis fluid through the dialysis fluid circuit and (ii) at least one of the fresh and spent dialysis fluid pumps to pump dialysis fluid through the dialyzer and into the extracorporeal circuit.
摘要:
A renal failure therapy method includes causing therapy fluid to flow to a renal failure therapy filter, directing at least twenty-five percent of the therapy fluid to the renal failure therapy filter to perform conductive clearance, and using the renal therapy failure filter to cause at least a substantial amount of the remaining therapy fluid to perform diffusive clearance.
摘要:
A hemodialysis system includes (i) a plurality of pump rollers: (ii) a fluid heater, the pump rollers and the heater positioned and arranged to accept a horizontally loaded dialysate cassette: (iii) a dialyzer; (iv) a sorbent cartridge; and (v) wherein the dialysate cassette includes first and second tubes for horizontal interaction with the pump rollers and a third tube for horizontal interaction with the heater, the cassette in fluid communication with the sorbent cartridge.
摘要:
A renal failure therapy method includes causing therapy fluid to flow to a renal failure therapy filter, directing at least twenty-five percent of the therapy fluid to the renal failure therapy filter to perform conductive clearance, and using the renal therapy failure filter to cause at least a substantial amount of the remaining therapy fluid to perform diffusive clearance.
摘要:
A hemodialysis system includes an on-line dialysate generator; a dialysate pump actuator configured to pump dialysate generated by the generator to a dialyzer; a conductivity sensor located adjacent to a temperature sensor upstream of the dialyzer; a blood pump actuator; an air detector; and a disposable cassette configured to carry dialysate pumped by the dialysate pump actuator, the disposable cassette including a conductivity sensor portion and a temperature sensor portion located to operate with the conductivity sensor and the temperature sensor, respectively, the disposable cassette further configured to carry blood pumped by the blood pump actuator and to provide an air detection portion located to operate with the air detector.
摘要:
A valve integrity method for a medical fluid pump includes pumping fluid into the medical fluid pump while an outlet valve is closed and an inlet valve is open, closing the inlet valve while the outlet valve is closed, attempting to pump fluid out of the medical fluid pump while the inlet valve and the outlet valve are closed, and determining that at least one of the valves is leaking if a change in medical fluid volume within the medical fluid pump is detected.
摘要:
A valve integrity method for a medical fluid pump includes pumping fluid into the medical fluid pump while an outlet valve is closed and an inlet valve is open, closing the inlet valve while the outlet valve is closed, attempting to pump fluid out of the medical fluid pump while the inlet valve and the outlet valve are closed, and determining that at least one of the valves is leaking if a change in medical fluid volume within the medical fluid pump is detected.
摘要:
A dialysis system includes a dialysis fluid cassette-based membrane blood pump; a dialyzer in fluid communication with the blood pump: first and second dialysis fluid cassette-based balance chambers each having (i) a fresh dialysis fluid compartment in fluid communication with the dialyzer and (ii) a spent dialysis fluid compartment; a dialysis fluid cassette-based fresh dialysis fluid membrane pump in fluid communication with the fresh dialysis fluid compartments of the first and second balance chambers; a dialysis fluid cassette-based spent dialysis fluid membrane pump in fluid communication with the dialyzer and the spent dialysis fluid compartments of the first and second balance chambers; and arterial and venous lines in fluid communication with the dialyzer for patient connection, the arterial and venous lines each including a contact used for electrically detecting a patient access disconnection.
摘要:
A hemodialysis system includes (i) a plurality of pump rollers: (ii) a fluid heater, the pump rollers and the heater positioned and arranged to accept a horizontally loaded dialysate cassette: (iii) a dialyzer; (iv) a sorbent cartridge; and (v) wherein the dialysate cassette includes first and second tubes for horizontal interaction with the pump rollers and a third tube for horizontal interaction with the heater, the cassette in fluid communication with the sorbent cartridge.