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    APPARATUS AND METHODS FOR VERTEBRAL AUGMENTATION USING LINKED EXPANDABLE BODIES
    2.
    发明申请
    APPARATUS AND METHODS FOR VERTEBRAL AUGMENTATION USING LINKED EXPANDABLE BODIES 有权
    使用连接的可扩展体进行VERTEBRAL补充的装置和方法

    公开(公告)号：US20120310355A1

    公开(公告)日：2012-12-06

    申请号：US13572975

    申请日：2012-08-13

    申请人： Christof Dutoit ,  Andreas Appenzeller ,  Thierry Stoll ,  Robert Frigg ,  Robert Rauker

    发明人： Christof Dutoit ,  Andreas Appenzeller ,  Thierry Stoll ,  Robert Frigg ,  Robert Rauker

    IPC分类号： A61F2/44

    CPC分类号： A61B17/68 ,  A61B17/7001 ,  A61B17/7007 ,  A61B17/7053 ,  A61B17/7059 ,  A61B17/7094 ,  A61B17/8004

    摘要： Implants and methods for osteopathic augmentation and repositioning of vertebrae may comprise a chain having one or more beads or bodies configured for insertion into a vertebral body. The one or more bodies may be expandable. As the chain is inserted into the vertebral body, it may fill a central portion thereof and can push against the inner sides of the endplates of the vertebral body, thereby providing structural support and tending to restore the vertebral body to its original height. The one or more bodies may have a first configuration dimensioned to pass through a catheter or other introducer, and may expand to a second, larger configuration after insertion into the bone in order to secure the chain within the bone.

    摘要翻译： 用于椎骨的增强和重新定位的植入物和方法可以包括具有一个或多个被配置用于插入椎体的小珠或体的链。 一个或多个主体可以是可扩展的。 当链条插入椎体时，它可以填充其中心部分并且可以推靠在椎体的终板的内侧，从而提供结构支撑并且倾向于将椎体恢复到其原始高度。 所述一个或多个主体可以具有尺寸适于穿过导管或其它导引器的第一构造，并且可以在插入到骨中之后扩展到第二较大构造，以将链固定在骨中。

    Apparatus and methods for vertebral augmentation
    4.
    发明申请
    Apparatus and methods for vertebral augmentation 有权
    用于脊椎增大的装置和方法

    公开(公告)号：US20070093846A1

    公开(公告)日：2007-04-26

    申请号：US11546579

    申请日：2006-10-10

    申请人： Robert Frigg ,  Christof Dutoit ,  Andreas Appenzeller ,  Thierry Stoll ,  Alfred Benoit ,  Christoph Fuerst ,  Paul Heini

    发明人： Robert Frigg ,  Christof Dutoit ,  Andreas Appenzeller ,  Thierry Stoll ,  Alfred Benoit ,  Christoph Fuerst ,  Paul Heini

    IPC分类号： A61B17/58

    CPC分类号： A61B17/7077 ,  A61B17/025 ,  A61B17/7079 ,  A61B17/8805 ,  A61B2017/0256

    摘要： Apparatuses and methods of treating a collapsed vertebra may include inserting cannulae into the damaged vertebral body and one or more adjacent vertebral bodies and repositioning the one or more adjacent vertebral bodies by manipulating one or more of the cannulae. Before or after repositioning the vertebral bodies, the method may further include passing through the cannula and into the damaged vertebra a disruption tool for fracturing the damaged vertebral body. Once the cortical bone is broken or otherwise disrupted, the height of the damaged vertebral body may be restored, for example by removing the disruption tool and inserting through the cannula another tool, implant, device and/or material to restore the height of the vertebral body and to restore normal spinal curvature in the affected area. Bone cement, bone chips, demineralized bone or other grafting material or filler may be added with or without an implanted device to augment the damaged vertebral body.

    摘要翻译： 治疗塌陷椎骨的装置和方法可以包括将插入物插入损伤的椎体和一个或多个相邻的椎体中，并通过操纵一个或多个插管重新定位所述一个或多个相邻的椎体。 在重新定位椎体之前或之后，该方法还可以包括穿过套管并进入损伤的椎骨中，用于破坏受损椎体的破裂工具。 一旦皮质骨被破坏或以其他方式破坏，可以恢复受损椎体的高度，例如通过去除破碎工具并插入穿过套管的另一工具，植入物，装置和/或材料以恢复脊椎的高度 并恢复受影响区域的正常脊柱弯曲。 可以在有或没有植入装置的情况下添加骨水泥，骨碎片，软化骨或其它接枝材料或填充物，以增加损伤的椎体。

    Bone-regeneration material
    6.
    发明授权
    Bone-regeneration material 有权
    骨再生材料

    公开(公告)号：US08540658B2

    公开(公告)日：2013-09-24

    申请号：US10370606

    申请日：2003-02-24

    申请人： Thierry Stoll

    发明人： Thierry Stoll

    IPC分类号： A61M31/00

    CPC分类号： A61L27/365 ,  A61F2/28 ,  A61F2/4601 ,  A61F2/4644 ,  A61F2002/2817 ,  A61F2310/00293 ,  A61L27/12 ,  A61L27/54 ,  A61L27/56 ,  A61L2430/02

    摘要： The invention relates to a process for producing a bone-regeneration material. According to the method, a bio-compatible, open-pored body is exposed to a vacuum and osteoinductive and/or osteogenic substances are absorbed into the pores of the body, for example by means of a vacuum generated therein. It is thus possible to produce a bone-regeneration material, which contains osteoinductive and/or osteogenic substances in the pores of the bio-compatible body, said substances acting as a network structure for new somatic cells that are to grow into the porous body.

    摘要翻译： 本发明涉及骨再生材料的制造方法。 根据该方法，将生物相容性开放的身体暴露于真空中，并且骨诱导和/或成骨物质例如通过其中产生的真空吸收到身体的孔中。 因此，可以生产在生物相容体的孔中含有骨诱导和/或成骨物质的骨再生材料，所述物质作为新生体细胞的网状结构，其生长到多孔体中。

    Apparatus and methods for treating bone
    7.
    发明授权
    Apparatus and methods for treating bone 有权
    用于治疗骨骼的装置和方法

    公开(公告)号：US08080061B2

    公开(公告)日：2011-12-20

    申请号：US11471169

    申请日：2006-06-19

    申请人： Andreas Appenzeller ,  Christof Dutoit ,  Alfred Benoit ,  Thierry Stoll ,  Erich Röthlisberger ,  Stefan Mathys

    发明人： Andreas Appenzeller ,  Christof Dutoit ,  Alfred Benoit ,  Thierry Stoll ,  Erich Röthlisberger ,  Stefan Mathys

    IPC分类号： A61F2/44 ,  A61B17/58

    CPC分类号： A61B17/742 ,  A61B17/7062 ,  A61B17/7095 ,  A61B17/8852 ,  A61B17/8858 ,  A61B2017/0256

    摘要： Implants and methods for bone treatment, preferably minimally invasive treatment, including repositioning of vertebrae may comprise insertion of a bobbin having a wire, string, thread or band, coiled around the bobbin. During coiling, the diameter of the bobbing/band complex may increase. Such increase in diameter can push against the inner side of the endplates of the vertebral body, and augment the vertebral body to its original height. The implant may also take the form of a coiled sleeve which when inserted into the vertebral body is uncoiled. The force of the uncoiling sleeve pushes against the inner side of the endplates of the vertebral body, restoring the vertebral body to its original height. The implant may also take the form of fibrous masses comprised of a thread or other relatively thin structure, for example a fiber or strand, of any biocompatible material having desired characteristics, for example a shape memory alloy, titanium, stainless steel, another metal or metal alloy, a ceramic, a composite or any combination thereof. The, strand, thread or other fiber may be coiled, woven, matted, tangled or otherwise formed into a wool-like mass or body having a desired configuration. Expansion of the expandable member within the vertebral body or other bone may reposition the fractured bone to a desired height and augment the bone to maintain the desired height. A bone cement or other filler can be added to further treat and stabilize the vertebral body or other bone.

    摘要翻译： 用于骨治疗的植入物和方法，优选微创治疗，包括椎骨的重新定位可以包括插入线圈，线圈，线或线圈绕线圈。 在卷取期间，摆动/带复合体的直径可能增加。 这种直径的增加可以推动椎体的终板的内侧，并将椎体增加到其原始高度。 植入物也可以采取螺旋形套筒的形式，当插入到椎体中时，其被展开。 开卷套筒的力推动椎体的端板的内侧，将椎体恢复到原来的高度。 植入物也可以采取由具有所需特征的任何具有所需特征的生物相容性材料，例如形状记忆合金，钛，不锈钢，另一种金属的线或其它较薄结构（例如纤维或股线）组成的纤维质量的形式， 金属合金，陶瓷，复合材料或其组合。 线，线或其他纤维可以卷绕，编织，消光，缠结或以其它方式形成具有所需构型的羊毛状物质或身体。 可扩展构件在椎体或其他骨骼内的扩张可以将骨折骨重新定位到期望的高度并增加骨骼以保持所需的高度。 可以加入骨水泥或其他填料以进一步治疗和稳定椎体或其他骨。

    METHOD TO IMPREGNATE A POROUS BONE REPLACEMENT MATERIAL
    8.
    发明申请
    METHOD TO IMPREGNATE A POROUS BONE REPLACEMENT MATERIAL 有权
    多孔骨替代材料的方法

    公开(公告)号：US20090022878A1

    公开(公告)日：2009-01-22

    申请号：US12242207

    申请日：2008-09-30

    申请人： Flavio Hoerger ,  Thierry Stoll

    发明人： Flavio Hoerger ,  Thierry Stoll

    IPC分类号： A61L27/00 ,  B05D3/00

    CPC分类号： A61L27/50 ,  A61B2050/0064 ,  A61F2/4644 ,  A61F2002/2835 ,  A61F2002/4685 ,  A61L24/0036 ,  A61L27/56 ,  A61L2430/02

    摘要： A method to impregnate a porous bone replacement material (1) with a liquid impregnating agent (5), wherein a) the bone replacement material (1) is or will be enclosed in a chamber (2) with two openings (3, 4) that can be closed, b) the impregnating agent (5) is introduced into the chamber (2) until the bone replacement material (1) is at least partly immersed in the impregnating agent (5), c) one of the two openings (3, 4) will be closed, d) the chamber (2) is evacuated at least partly via the other, open, opening (4, 3), so that the air contained in the pores of the bone replacement material (1) is at least partly removed from it, e) the vacuum produced in the chamber is terminated again by supplying air or a gas through one of the openings (3, 4), and f) the vacuum produced in the pores of the bone replacement material (1) is terminated by the impregnating agent (5) penetrating into the pores of the bone replacement material (1) immersed into the impregnating agent (5).

    摘要翻译： 一种用液体浸渍剂（5）浸渍多孔骨置换材料（1）的方法，其中a）所述骨置换材料（1）将被封闭在具有两个开口（3,4）的腔室（2）中， b）将浸渍剂（5）引入到室（2）中，直到骨置换材料（1）至少部分地浸入浸渍剂（5）中，c）两个开口 （4）将被关闭，d）腔室（2）至少部分地通过另一个打开的开口（4,3）抽空，使得包含在骨置换材料（1）的孔中的空气是 至少部分地从其中除去，e）通过将空气或气体通过其中一个开口（3,4）供应空气或再次终止在室中产生的真空，以及f）在骨置换材料的孔中产生的真空 1）被渗透到浸渍在浸渍剂（5）中的骨置换材料（1）的孔中的浸渍剂（5）终止。

    Bone-regeneration material
    9.
    发明申请
    Bone-regeneration material 有权
    骨再生材料

    公开(公告)号：US20050074433A1

    公开(公告)日：2005-04-07

    申请号：US10370606

    申请日：2003-02-24

    申请人： Thierry Stoll

    发明人： Thierry Stoll

    IPC分类号： A61L27/00 ,  A61F2/00 ,  A61F2/28 ,  A61F2/46 ,  A61L27/12 ,  A61K45/00

    CPC分类号： A61L27/365 ,  A61F2/28 ,  A61F2/4601 ,  A61F2/4644 ,  A61F2002/2817 ,  A61F2310/00293 ,  A61L27/12 ,  A61L27/54 ,  A61L27/56 ,  A61L2430/02

    摘要： The invention relates to a process for producing a bone-regeneration material. According to the method, a bio-compatible, open-pored body is exposed to a vacuum and osteoinductive and/or osteogenic substances are absorbed into the pores of the body, for example by means of a vacuum generated therein. It is thus possible to produce a bone-regeneration material, which contains osteoinductive and/or osteogenic substances in the pores of the bio-compatible body, said substances acting as a network structure for new somatic cells that are to grow into the porous body.

    摘要翻译： 本发明涉及骨再生材料的制造方法。 根据该方法，将生物相容性开放的身体暴露于真空中，并且骨诱导和/或成骨物质例如通过其中产生的真空吸收到身体的孔中。 因此，可以生产在生物相容体的孔中含有骨诱导和/或成骨物质的骨再生材料，所述物质作为新生体细胞的网状结构，其生长到多孔体中。

    Method to impregnate a porous bone replacement material
    10.
    发明授权
    Method to impregnate a porous bone replacement material 有权
    浸渍多孔骨置换材料的方法

    公开(公告)号：US08632242B2

    公开(公告)日：2014-01-21

    申请号：US13744744

    申请日：2013-01-18

    申请人： Flavio Hoerger ,  Thierry Stoll

    发明人： Flavio Hoerger ,  Thierry Stoll

    IPC分类号： B01F13/06 ,  B01F15/02

    CPC分类号： A61L27/50 ,  A61B2050/0064 ,  A61F2/4644 ,  A61F2002/2835 ,  A61F2002/4685 ,  A61L24/0036 ,  A61L27/56 ,  A61L2430/02

    摘要： A method to impregnate a porous bone replacement material (1) with a liquid impregnating agent (5), wherein a) the bone replacement material (1) is or will be enclosed in a chamber (2) with two openings (3, 4) that can be closed, b) the impregnating agent (5) is introduced into the chamber (2) until the bone replacement material (1) is at least partly immersed in the impregnating agent (5), c) one of the two openings (3, 4) will be closed, d) the chamber (2) is evacuated at least partly via the other, open, opening (4, 3), so that the air contained in the pores of the bone replacement material (1) is at least partly removed from it, e) the vacuum produced in the chamber is terminated again by supplying air or a gas through one of the openings (3, 4), and f) the vacuum produced in the pores of the bone replacement material (1) is terminated by the impregnating agent (5) penetrating into the pores of the bone replacement material (1) immersed into the impregnating agent (5).

    摘要翻译： 一种用液体浸渍剂（5）浸渍多孔骨置换材料（1）的方法，其中a）所述骨置换材料（1）将被封闭在具有两个开口（3,4）的腔室（2）中， b）将浸渍剂（5）引入到室（2）中，直到骨置换材料（1）至少部分地浸入浸渍剂（5）中，c）两个开口 （4）将被关闭，d）腔室（2）至少部分地通过另一个打开的开口（4,3）抽空，使得包含在骨置换材料（1）的孔中的空气是 至少部分地从其中除去，e）通过将空气或气体通过其中一个开口（3,4）供应空气或再次终止在室中产生的真空，以及f）在骨置换材料的孔中产生的真空 1）被渗透到浸渍在浸渍剂（5）中的骨置换材料（1）的孔中的浸渍剂（5）终止。