公开(公告)号：US09450382B2

公开(公告)日：2016-09-20

申请号：US13894127

申请日：2013-05-14

申请人： Björn Dirumdam ,  Ingo Wilke

发明人： Björn Dirumdam ,  Ingo Wilke

IPC分类号： F02P7/02 ,  H01T13/14 ,  H01T13/46 ,  F02P7/063 ,  F02D17/04 ,  B60R25/04 ,  F01M1/26

CPC分类号： H01T13/14 ,  B60R25/04 ,  F01M1/26 ,  F02D17/04 ,  F02P7/021 ,  F02P7/0632 ,  H01T13/467

摘要： Spark plug for an internal combustion engine, having a center electrode and a ground electrode arranged in radial direction around the center electrode, wherein an annular spark gap is formed between the center electrode and the ground electrode for igniting a fuel mixture by means of an electric ignition spark developing between the center electrode and the ground electrode, and wherein the ground electrode is contoured in such a way that particles reaching the region of the ground electrode can be removed from the spark gap under the influence of gravitational force.

摘要翻译： 用于内燃机的火花塞，具有围绕中心电极沿径向布置的中心电极和接地电极，其中在中心电极和接地电极之间形成环形火花隙，用于通过电气点燃燃料混合物 在中心电极和接地电极之间产生点火火花，并且其中接地电极的轮廓使得在重力的影响下到达接地电极的区域的颗粒可以从火花隙中去除。

公开(公告)号：US20130196380A1

公开(公告)日：2013-08-01

申请号：US13576006

申请日：2011-02-04

申请人： Wolfgang Lüeke ,  Peter Miethe ,  Katrin Mueller-Zahm ,  Ingo Wilke ,  Gabriele Jansen

发明人： Wolfgang Lüeke ,  Peter Miethe ,  Katrin Mueller-Zahm ,  Ingo Wilke ,  Gabriele Jansen

IPC分类号： C12P21/00

CPC分类号： C12P21/00 ,  C07K16/00 ,  C07K16/081 ,  C07K16/1282 ,  C07K16/14 ,  C07K16/16 ,  C07K2317/10 ,  C07K2317/21

摘要： An in vitro process for the preparation of antibodies of the IgG type, comprising the steps of: i. challenging dendritic cells obtained from a donor with an antigen against which the antibodies to be prepared are directed; ii. challenging CD4+ T cells obtained from the same donor with fragments of the antigen presented by the dendritic cells from step L, with the proviso that the dendritic cells are ones essentially not secreting interferon-γ (IFN-γ) and interleukin 12 (IL-12), to generate antigen-specific CD4+ Th2 cells; iii. challenging with the antigen a B cell population obtained from the same donor and including a sufficient proportion of naive B cells; and iv. contacting the antigen-specific CD4+ Th2 cells according to ii. with at least a fraction of the B cell population from iii. to form an antigen-specific plasma cell; v. immortalizing said antigen-specific plasma cell; and vi. isolating the IgG antibodies formed by said antigen-specific plasma cell.

摘要翻译： 用于制备IgG型抗体的体外方法，包括以下步骤：i。 从具有待制备的抗体的抗原的供体获得的具有挑战性的树突状细胞; ii。 挑选与来自步骤L的树突状细胞呈递的抗原片段相同供体的CD4 + T细胞，条件是树突细胞基本上不分泌干扰素-γ（IFN-γ）和白细胞介素12（IL-12） ），以产生抗原特异性CD4 + Th2细胞; iii。 与抗原挑战从相同供体获得的B细胞群体，并包括足够比例的幼稚B细胞; 和iv。 根据ii。接触抗原特异性CD4 + Th2细胞。 其中至少一部分来自iii的B细胞群体。 以形成抗原特异性浆细胞; v永生化所述抗原特异性浆细胞; 和vi。 分离由所述抗原特异性浆细胞形成的IgG抗体。

公开(公告)号：US20050249709A1

公开(公告)日：2005-11-10

申请号：US11088784

申请日：2005-03-25

申请人： Erhardt Wrabetz ,  Michael Rode ,  Thierry Stoll ,  Stephan Becker ,  Ingo Wilke

发明人： Erhardt Wrabetz ,  Michael Rode ,  Thierry Stoll ,  Stephan Becker ,  Ingo Wilke

IPC分类号： A61L27/00 ,  A61F2/28 ,  A61K38/36 ,  A61L27/34 ,  A61L27/38 ,  A61L27/42 ,  A61L27/54 ,  A61L27/56 ,  A61K45/00 ,  A61F2/00

CPC分类号： A61L27/54 ,  A61L27/425 ,  A61L27/56 ,  A61L2300/418 ,  A61L2430/02

摘要： A bone substitute which consists of a porous metallic or a biocompatible, open-cell material which is wholly or partly impregnated with a solution comprising factor XIII, or at least some of its pores are filled with a solution comprising factor XIII, is described.

摘要翻译： 描述了由包含因子XIII或其至少一些孔隙的溶液全部或部分浸渍的多孔金属或生物相容的开孔细胞材料构成的骨替代物，其被填充有包含因子XIII的溶液。

公开(公告)号：US09528463B2

公开(公告)日：2016-12-27

申请号：US13563954

申请日：2012-08-01

申请人： Sascha Stoll ,  Ingo Wilke

发明人： Sascha Stoll ,  Ingo Wilke

IPC分类号： F02D41/22 ,  F02M21/02 ,  F02D19/02 ,  F02D41/00 ,  F02B19/12

CPC分类号： F02D41/22 ,  F02B19/12 ,  F02D19/025 ,  F02D19/027 ,  F02D41/0027 ,  F02M21/0242 ,  F02M21/0275 ,  Y02T10/125 ,  Y02T10/32 ,  Y02T10/40

摘要： A method of monitoring check valves (6) arranged in gas feed lines (5) of a gas engine includes determining a temperature (S1) according to which a signal transmitter is activated (S3) when a detected temperature in a gas feed line (5) lies outside of a first designated target range; and transmitting (S3) a signal which carries information indicating the gas feed line (5) in which the temperature lying outside of the first target range was detected and/or the cylinder (10) with which the gas feed line (5) is associated.

摘要翻译： 一种监视配置在燃气发动机的气体供给管线（5）中的止回阀（6）的方法，包括：当气体供给管线（5）中检测到的温度时，确定启动信号发送器的温度（S1）（S3） ）位于第一指定目标范围之外; 并且发送（S3）携带指示其中检测到位于第一目标范围之外的温度的气体供给管线（5）的信息的信号和/或气体供给管线（5）与其相关联的气缸（10） 。

公开(公告)号：US20130312692A1

公开(公告)日：2013-11-28

申请号：US13894127

申请日：2013-05-14

申请人： Björn Dirumdam ,  Ingo Wilke

发明人： Björn Dirumdam ,  Ingo Wilke

IPC分类号： H01T13/14

CPC分类号： H01T13/14 ,  B60R25/04 ,  F01M1/26 ,  F02D17/04 ,  F02P7/021 ,  F02P7/0632 ,  H01T13/467

摘要： Spark plug for an internal combustion engine, having a center electrode and a ground electrode arranged in radial direction around the center electrode, wherein an annular spark gap is formed between the center electrode and the ground electrode for igniting a fuel mixture by means of an electric ignition spark developing between the center electrode and the ground electrode, and wherein the ground electrode is contoured in such a way that particles reaching the region of the ground electrode can be removed from the spark gap under the influence of gravitational force.

摘要翻译： 用于内燃机的火花塞，具有围绕中心电极沿径向布置的中心电极和接地电极，其中在中心电极和接地电极之间形成环形火花隙，用于通过电气点燃燃料混合物 在中心电极和接地电极之间产生点火火花，并且其中接地电极的轮廓使得在重力的影响下到达接地电极的区域的颗粒可以从火花隙中去除。

公开(公告)号：US20130054124A1

公开(公告)日：2013-02-28

申请号：US13563954

申请日：2012-08-01

申请人： Sascha Stoll ,  Ingo Wilke

发明人： Sascha Stoll ,  Ingo Wilke

IPC分类号： G01K13/02 ,  F02B19/00 ,  F02D41/26

CPC分类号： F02D41/22 ,  F02B19/12 ,  F02D19/025 ,  F02D19/027 ,  F02D41/0027 ,  F02M21/0242 ,  F02M21/0275 ,  Y02T10/125 ,  Y02T10/32 ,  Y02T10/40

摘要： A method of monitoring check valves (6) arranged in gas feed lines (5) of a gas engine includes determining a temperature (S1) according to which a signal transmitter is activated (S3) when a detected temperature in a gas feed line (5) lies outside of a first designated target range; and transmitting (S3) a signal which carries information indicating the gas feed line (5) in which the temperature lying outside of the first target range was detected and/or the cylinder (10) with which the gas feed line (5) is associated.

摘要翻译： 一种监视配置在燃气发动机的气体供给管线（5）中的止回阀（6）的方法，包括：当气体供给管线（5）中检测到的温度时，确定启动信号发送器的温度（S1）（S3） ）位于第一指定目标范围之外; 并且发送（S3）携带指示其中检测到位于第一目标范围之外的温度的气体供给管线（5）的信息的信号和/或与气体供给管线（5）相关联的气缸（10） 。

公开(公告)号：US06312568B2

公开(公告)日：2001-11-06

申请号：US09456130

申请日：1999-12-07

申请人： Ingo Wilke ,  Rochelle King ,  Hoa Kieu

发明人： Ingo Wilke ,  Rochelle King ,  Hoa Kieu

IPC分类号： C23C1434

CPC分类号： C23C14/0042 ,  C23C14/0617 ,  H01L41/316

摘要： The present invention provides a method of forming an aluminum nitride layer on a substrate in a processing chamber comprising depositing a first aluminum nitride layer at a first chamber pressure on a substrate, and then depositing a second aluminum nitride layer at a second chamber pressure higher than the first chamber pressure on the aluminum nitride nucleating layer. The first aluminum nitride layer is deposited by sputtering an aluminum target in a nitrogen and inert gas plasma in a processing chamber at a chamber pressure of about 1.5 to about 3 milliTorr. The second aluminum nitride layer is deposited by sputtering an aluminum target in a nitrogen and inert gas plasma at a chamber pressure of about 5 to about 10 milliTorr. The process may be carried out in the same physical vapor deposition chamber with the substrate being maintained at a temperature of preferably between about 125° C. and about 500° C. The advantages provided by the invention include an improved deposition rate for aluminum nitride with a preferred crystal orientation and improved layer properties.

摘要翻译： 本发明提供了一种在处理室中的衬底上形成氮化铝层的方法，该方法包括：在第一室压力下在衬底上沉积第一氮化铝层，然后在第二室压力下沉积第二氮化铝层， 氮化铝成核层上的第一室压力。 通过在约1.5至约3毫乇的室压力下在处理室中将氮靶和惰性气体等离子体中的铝靶溅射到第一氮化铝层。 第二氮化铝层通过在约5至约10毫乇的室压力下将铝靶溅射在氮气和惰性气体等离子体中来沉积。 该方法可以在相同的物理气相沉积室中进行，其中基底保持在约125℃至约500℃之间的温度。本发明提供的优点包括改进的氮化铝沉积速率 优选的晶体取向和改进的层性质。