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    Quantitative method and apparatus for measuring QT intervals from ambulatory electrocardiographic recordings
    2.
    发明授权
    Quantitative method and apparatus for measuring QT intervals from ambulatory electrocardiographic recordings 有权
    用于测量动态心电图记录的QT间期的定量方法和装置

    公开(公告)号：US06324423B1

    公开(公告)日：2001-11-27

    申请号：US09292995

    申请日：1999-04-16

    Applicant: Timothy Callahan ,  William Shell

    Inventor： Timothy Callahan ,  William Shell

    IPC: A61B50452

    CPC classification number: A61B5/0468 ,  A61B5/02405 ,  A61B5/0452

    Abstract: A quantitative method and apparatus for measuring a cardiac function interval. Beat-to-beat data representative of a cardiac interval is collected over an extended period of time. A series of bins, each of which has a defined value range, is defined. The collected data is organized into the bins in accordance with the value of the data and the value range of the bin. The percentage of data in each bin may be calculated based upon the quantity of data in each bin.

    Abstract translation: 用于测量心脏功能间隔的定量方法和装置。 在更长的时间内收集代表心脏间隔的节拍数据。 定义了一系列具有定义值范围的分箱。 收集的数据根据​​数据的值和bin的值范围进行组织。 可以根据每个仓中的数据量来计算每个仓中的数据百分比。

    Composition and method to augment and sustain neurotransmitter production
    3.
    发明授权
    Composition and method to augment and sustain neurotransmitter production 有权
    增加和维持神经递质生成的组成和方法

    公开(公告)号：US07595067B2

    公开(公告)日：2009-09-29

    申请号：US11714052

    申请日：2007-03-05

    Applicant: William Shell ,  Elizabeth Charuvastra

    Inventor： William Shell ,  Elizabeth Charuvastra

    IPC: A61K36/25 ,  A61K36/734 ,  A61K36/00 ,  A61K36/16 ,  A61K36/254 ,  A61K36/54 ,  A61K36/28

    CPC classification number: A61K31/522 ,  A23L33/105 ,  A23V2002/00 ,  A61K36/16 ,  A61K36/185 ,  A61K36/258 ,  A61K36/28 ,  A61K36/38 ,  A61K36/54 ,  A61K36/734 ,  A61K45/06 ,  A61K2300/00 ,  A23V2250/2108 ,  A23V2250/0624 ,  A23V2250/0652 ,  A23V2250/2122 ,  A23V2250/304 ,  A23V2250/0618 ,  A23V2250/2106

    Abstract: This invention describes a method and composition to enhance the synthesis and release of the neurotransmitters by the oral administration of neurotransmitter precursors, along with natural plant substances that stimulate uptake of the neurotransmitters precursors, while adding natural plant substances that activate adenylate cyclase in order to avoid attenuation and prevent pharmacologic tolerance. The invention describes compositions for a medical foods that are designed to improve cognitive function, induced sleep, a improve Parasympathetic function, improve autonomic balance, increase nitric oxide production, reduce blood pressure, increase blood flow, and treat virus infections. The compositions include amino acids such as choline, herbs such ginkgo biloba, and other foods such as coca. The invention also describes the use of physiologic tests such as 24 hour ECG monitoring to create the appropriate combinations and assess the useful proportions.

    Abstract translation: 本发明描述了通过口服神经递质前体以及刺激神经递质前体摄取的天然植物物质来增强神经递质的合成和释放的方法和组合物，同时加入激活腺苷酸环化酶的天然植物物质以避免 衰减并防止药理学耐受。 本发明描述了旨在改善认知功能，诱导睡眠，改善副交感神经功能，改善自主神经平衡，增加一氧化氮产生，降低血压，增加血流量和治疗病毒感染的医用食品的组合物。 组合物包括氨基酸如胆碱，草本银杏和其他食物如古柯。 本发明还描述了诸如24小时ECG监测的生理测试的使用以产生适当的组合并评估有用的比例。

    Composition and method to augment and sustain neurotransmitter production
    8.
    发明申请
    Composition and method to augment and sustain neurotransmitter production 有权
    增加和维持神经递质生成的组成和方法

    公开(公告)号：US20070160690A1

    公开(公告)日：2007-07-12

    申请号：US11713907

    申请日：2007-03-05

    Applicant: William Shell ,  Elizabeth Charuvastra

    Inventor： William Shell ,  Elizabeth Charuvastra

    IPC: A61K36/254 ,  A61K36/38 ,  A61K36/54 ,  A61K36/16 ,  A61K36/73 ,  A61K31/522 ,  A61K31/405

    CPC classification number: A61K31/522 ,  A23L33/105 ,  A23V2002/00 ,  A61K36/16 ,  A61K36/185 ,  A61K36/258 ,  A61K36/28 ,  A61K36/38 ,  A61K36/54 ,  A61K36/734 ,  A61K45/06 ,  A61K2300/00 ,  A23V2250/2108 ,  A23V2250/0624 ,  A23V2250/0652 ,  A23V2250/2122 ,  A23V2250/304 ,  A23V2250/0618 ,  A23V2250/2106

    Abstract: This invention describes a method and composition to enhance the synthesis and release of the neurotransmitters by the oral administration of neurotransmitter precursors, along with natural plant substances that stimulate uptake of the neurotransmitters precursors, while adding natural plant substances that activate adenylate cyclase in order to avoid attenuation and prevent pharmacologic tolerance. The invention describes compositions for a medical foods that are designed to improve cognitive function, induced sleep, a improve Parasympathetic function, improve autonomic balance, increase nitric oxide production, reduce blood pressure, increase blood flow, and treat virus infections. The compositions include amino acids such as choline, herbs such ginkgo biloba, and other foods such as coca. The invention also describes the use of physiologic tests such as 24 hour ECG monitoring to create the appropriate combinations and assess the useful proportions.

    Abstract translation: 本发明描述了通过口服神经递质前体以及刺激神经递质前体摄取的天然植物物质来增强神经递质的合成和释放的方法和组合物，同时加入激活腺苷酸环化酶的天然植物物质以避免 衰减并防止药理学耐受。 本发明描述了旨在改善认知功能，诱导睡眠，改善副交感神经功能，改善自主神经平衡，增加一氧化氮产生，降低血压，增加血流量和治疗病毒感染的医用食品的组合物。 组合物包括氨基酸如胆碱，草本银杏和其他食物如古柯。 本发明还描述了诸如24小时ECG监测的生理测试的使用以产生适当的组合并评估有用的比例。

    Visualization of a bloodstream circulation with biodegradable microspheres
    9.
    发明授权
    Visualization of a bloodstream circulation with biodegradable microspheres 失效
    用可生物降解的微球显示血流循环

    公开(公告)号：US4680171A

    公开(公告)日：1987-07-14

    申请号：US712038

    申请日：1985-03-15

    Applicant: William Shell

    Inventor： William Shell

    IPC: A61K9/16 ,  A61K49/04

    CPC classification number: A61K49/0419 ,  A61K9/1658 ,  Y10S424/90

    Abstract: An inexpensive and easy to use method of visualizing an arterial circulation using biodegradable microspheres dyed with an X-ray absorbent material, which enables the diagnosis of pulmonary embolism, is provided. The microspheres may be comprised of a variety of materials, including human albumin, and may be dyed with a number of X-ray absorbent materials, including hypaque-sodium and potassium iodide. The microspheres are injected into bloodstream at a particular location such that they travel through the desired arterial circulation, where they become lodged. Upon exposure of the arterial circulation to X-rays, blood vessels therein containing the microspheres will absorb the X-rays, causing them to show on a developed X-ray in contrast to other blood vessels and body tissue which do not contain the microspheres that transmit the X-rays. The microspheres are designed to dissolve into the bloodstream within fifteen to thirty minutes after their introduction, the X-ray dye being ultimately excreted from the body via the urine or metabolized by the liver.

    Abstract translation: 提供了一种使用能够诊断肺栓塞的X射线吸收材料染色的可生物降解的微球观察动脉循环的便宜且易于使用的方法。 微球可以由各种材料组成，包括人白蛋白，并且可以用许多X射线吸收材料染色，包括淡斑钠和碘化钾。 将微球注射到特定位置的血流中，使得它们穿过期望的动脉循环，在那里它们被放置。 当动脉循环暴露于X射线时，其中含有微球的血管将吸收X射线，导致它们显示在显影X射线上，与其他血管和不含微球体的身体组织相反， 传输X射线。 微球被设计成在引入后十五到三十分钟内溶解到血液中，X射线染料最终通过尿液从体内排出或被肝脏代谢。

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