公开(公告)号：US20230371555A1

公开(公告)日：2023-11-23

申请号：US18137635

申请日：2023-04-21

申请人： Lennham Pharmaceuticals, Inc.

发明人： Bradford C. Sippy

IPC分类号： A23L2/56 ,  A23L27/30 ,  A23L27/20 ,  A23L27/21 ,  A23L27/00 ,  A23L33/15 ,  A23L33/175 ,  A23L2/60

CPC分类号： A23L2/56 ,  A23L27/31 ,  A23L27/2054 ,  A23L27/21 ,  A23L27/88 ,  A23L33/15 ,  A23L33/175 ,  A23L2/60 ,  A23V2250/2108 ,  A23V2002/00 ,  A23V2200/33 ,  A23V2250/154 ,  A23V2250/0644 ,  A23V2250/7052 ,  A23V2250/706 ,  A23V2250/7056 ,  A23V2250/7046 ,  A23V2250/161 ,  A23V2250/705 ,  A23V2250/0652 ,  A23V2250/0638 ,  A23V2250/708

摘要： Provided herein are compositions (e.g., pharmaceutical compositions, nutraceutical compositions, foods, beverages, cosmetic compositions, diet supplements) comprising deuterated caffeine. The provided compositions may be useful for treating and/or preventing various diseases and conditions, such as obesity, causing weight loss, increasing metabolic rate, reducing appetite, increasing energy expenditure, increasing urine output, increasing sodium excretion, reducing edema, a pain disorder, apnea, hypotension, an encephalopathy, a neurological or psychiatric disorder, and an inflammatory disorder.

公开(公告)号：US20180228199A1

公开(公告)日：2018-08-16

申请号：US15954692

申请日：2018-04-17

申请人： International IP Holdings LLC

发明人： Manoj Bhargava

IPC分类号： A23L33/00 ,  A23L33/175 ,  A23L33/15 ,  A23L2/38 ,  A23L2/52 ,  A23L2/56 ,  A23L27/00

CPC分类号： A23L33/40 ,  A23L2/38 ,  A23L2/52 ,  A23L2/56 ,  A23L27/00 ,  A23L33/10 ,  A23L33/105 ,  A23L33/15 ,  A23L33/175 ,  A23V2002/00 ,  A23V2200/33 ,  A23V2250/044 ,  A23V2250/0638 ,  A23V2250/0644 ,  A23V2250/0652 ,  A23V2250/2108 ,  A23V2250/264 ,  A23V2250/304 ,  A23V2250/7046 ,  A23V2250/7052 ,  A23V2250/7056 ,  A23V2250/706

摘要： An energy composition includes a methylated xanthine, a choline derivative, and at least one flavorant in a sufficient amount to render the energy composition palatable. The energy composition may also include vitamins, amino acids, enzymes, preservatives, and the like.

公开(公告)号：US09943098B2

公开(公告)日：2018-04-17

申请号：US15390571

申请日：2016-12-26

申请人： International IP Holdings LLC

发明人： Manoj Bhargava

IPC分类号： A23L1/302 ,  A23L1/305 ,  A23L33/00 ,  A23L33/15 ,  A23L33/175 ,  A23L2/38 ,  A23L2/52 ,  A23L2/56 ,  A23L27/00

CPC分类号： A23L33/40 ,  A23L2/38 ,  A23L2/52 ,  A23L2/56 ,  A23L27/00 ,  A23L33/10 ,  A23L33/105 ,  A23L33/15 ,  A23L33/175 ,  A23V2002/00 ,  A23V2200/33 ,  A23V2250/044 ,  A23V2250/0638 ,  A23V2250/0644 ,  A23V2250/0652 ,  A23V2250/2108 ,  A23V2250/264 ,  A23V2250/304 ,  A23V2250/7046 ,  A23V2250/7052 ,  A23V2250/7056 ,  A23V2250/706

摘要： An energy composition includes a methylated xanthine, a choline derivative, and at least one flavorant in a sufficient amount to render the energy composition palatable. The energy composition may also include vitamins, amino acids, enzymes, preservatives, and the like.

公开(公告)号：US09682024B2

公开(公告)日：2017-06-20

申请号：US14925709

申请日：2015-10-28

申请人： ZeaVision, LLC

发明人： Dennis L. Gierhart ,  Joseph A. Fox

IPC分类号： A61K31/05 ,  A61K8/34 ,  A61K8/31 ,  A61K31/015 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/04 ,  A61K45/06 ,  A61K8/27 ,  A61K8/92 ,  A61K8/97 ,  A23L33/175

CPC分类号： A61K8/345 ,  A23L33/175 ,  A23V2002/00 ,  A61K8/27 ,  A61K8/31 ,  A61K8/922 ,  A61K8/97 ,  A61K31/015 ,  A61K31/047 ,  A61K31/05 ,  A61K45/06 ,  A61K2800/81 ,  A61K2800/92 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/04 ,  A23V2200/308 ,  A23V2250/0632 ,  A23V2250/065 ,  A23V2250/0626 ,  A23V2250/0628 ,  A23V2250/063 ,  A23V2250/0638 ,  A23V2250/0648 ,  A23V2250/0654 ,  A23V2250/0604 ,  A23V2250/0606 ,  A23V2250/0608 ,  A23V2250/0616 ,  A23V2250/0618 ,  A23V2250/0622 ,  A23V2250/064 ,  A23V2250/0642 ,  A23V2250/0652 ,  A23V2250/0624 ,  A61K2300/00

摘要： Zeaxanthin is ingested orally at suitable dosages that gives skin a darker tint that emulates a healthy suntan and that reduces the severity of unwanted skin discoloration or irregularities. In tests involving adults, it was found that zeaxanthin dosages of 30 to about 80 mg per day were sufficient to induce a mild but noticeable tinting, shading, or darkening of skin color, comparable to a mild suntan, a substantial increase in the person's ability to withstand elevated levels of sun or UV exposure without any subsequent pain or discomfort, and without the subsequent peeling and flaking that characterizes sunburns, and an increased ability of reddened and sunburned skin to convert into intact skin that looks browned and healthily tanned. The topical application of zeaxanthin can further enhance the darkening of the skin and reduce the severity of unwanted skin discoloration or irregularities.

公开(公告)号：US20170027212A1

公开(公告)日：2017-02-02

申请号：US15302722

申请日：2015-04-08

申请人： NESTEC S.A.

发明人： Michael Affolter ,  Sagar Thakkar ,  Carlos Antonio De Castro

IPC分类号： A23L33/175 ,  A23L33/00

CPC分类号： A23L33/175 ,  A23L33/10 ,  A23L33/17 ,  A23L33/19 ,  A23L33/40 ,  A23V2002/00 ,  A23V2200/00 ,  A23V2200/30 ,  A23V2250/0628 ,  A23V2250/0648 ,  A23V2250/0652

摘要： Gender specific synthetic nutritional compositions for infants up to 1 month of age, wherein the leucine and/or threonine and/or tyrosine content is adapted based on that found in HM produced for an infant of the same gender and age, and nutritional systems comprising them.

摘要翻译： 基于针对相同性别和年龄的婴儿生产的HM中发现的亮氨酸和/或苏氨酸和/或酪氨酸含量，以及包含它们的营养系统，适用于至少1个月龄的婴儿的性别特异性合成营养组合物 。

公开(公告)号：US09186350B2

公开(公告)日：2015-11-17

申请号：US13547757

申请日：2012-07-12

申请人： Gregory Blackman

发明人： Gregory Blackman

IPC分类号： A61K8/31 ,  A61K31/4015 ,  A61K31/133 ,  A61K31/137 ,  A61K31/197 ,  A61K31/198 ,  A61K31/352 ,  A61K31/4375 ,  A61K31/4415 ,  A61K31/455 ,  A61K31/51 ,  A61K31/519 ,  A61K31/525 ,  A61K31/714 ,  A61K31/732 ,  A61K36/752 ,  A61K45/06 ,  A23L1/302 ,  A23L1/304 ,  A23L1/305 ,  A23L1/308 ,  A61K36/28 ,  A61K36/73 ,  A61K9/00 ,  A61K8/67 ,  A61K8/19

CPC分类号： A61K36/752 ,  A23L33/15 ,  A23L33/16 ,  A23L33/175 ,  A23L33/21 ,  A23V2002/00 ,  A61K8/19 ,  A61K8/31 ,  A61K8/67 ,  A61K8/673 ,  A61K9/0095 ,  A61K9/08 ,  A61K31/133 ,  A61K31/137 ,  A61K31/197 ,  A61K31/198 ,  A61K31/352 ,  A61K31/4015 ,  A61K31/4375 ,  A61K31/4415 ,  A61K31/455 ,  A61K31/51 ,  A61K31/519 ,  A61K31/525 ,  A61K31/714 ,  A61K31/732 ,  A61K36/28 ,  A61K36/73 ,  A61K45/06 ,  A61K2300/00 ,  A23V2200/334 ,  A23V2250/0616 ,  A23V2250/0634 ,  A23V2250/16 ,  A23V2250/161 ,  A23V2250/1614 ,  A23V2250/21168 ,  A23V2250/5072 ,  A23V2250/7042 ,  A23V2250/7044 ,  A23V2250/7046 ,  A23V2250/705 ,  A23V2250/7052 ,  A23V2250/706 ,  A23V2250/0652 ,  A23V2250/7054 ,  A23V2250/7058

摘要： The present invention relates to a composition, and methods of using the composition, for minimizing the harmful effects associated with alcohol consumption. The composition includes a plurality of ingredients, which when combined, have the unexpected effect of increasing one or more metabolic pathways in the individual. As the metabolic rate is increased, alcohol is burned off, or utilized as energy source, and occurs at a considerably much faster rate than under normal physiological means. It is believed that the composition may have an effect on the brain causing it to increase metabolic rates. By administering the composition to an inebriated individual, the rate at which a person sobers up, occurs at a faster rate than would occur under normal physiological time frames.

摘要翻译： 本发明涉及一种组合物，以及使用该组合物以最小化与饮酒相关的有害影响的方法。 组合物包括多种成分，当其组合时，具有增加个体中一种或多种代谢途径的意想不到的效果。 随着代谢率的增加，酒精被烧掉或被用作能量源，发生速度要比正常生理手段快得多。 据信该组合物可能对脑有影响，导致其增加代谢率。 通过将组合物施用于醉酒个体，人的清醒速度发生在比在正常生理时间范围内发生的更快的速率。

公开(公告)号：US20150224082A1

公开(公告)日：2015-08-13

申请号：US14695859

申请日：2015-04-24

申请人： Raymond Michael Keller

发明人： Raymond Michael Keller

IPC分类号： A61K31/405 ,  A61K31/197 ,  A61M21/02 ,  A61M15/06 ,  A61M16/10 ,  A61K31/4045 ,  A61K9/00

CPC分类号： A61K31/405 ,  A23L33/15 ,  A23L33/175 ,  A23V2002/00 ,  A61K9/0073 ,  A61K31/197 ,  A61K31/4045 ,  A61M15/06 ,  A61M16/109 ,  A61M21/02 ,  A61M2205/36 ,  C07C229/36 ,  C07D209/16 ,  C07D209/20 ,  A23V2200/31 ,  A23V2250/044 ,  A23V2250/065 ,  A23V2250/0652 ,  A23V2250/7046 ,  A23V2250/7052

摘要： A relaxation formulation structured to induce a deep state of relaxation in a person comprises amounts of tryptophan, melatonin, vitamin B3, and vitamin B6. Another relaxation formulation also includes an amount of tyrosine, and yet another formulation includes an amount of vitamin B12. At least one embodiment of a relaxation formula comprises a physiologically effective amount of gamma-aminobutyric acid (“GABA”). A delivery system is provided to facilitate administration of the relaxation formulation to a person. The delivery system may include an edible high carbohydrate matrix, such as a chocolate brownie. Alternatively, the delivery system may comprise an inert vaporizable compound to allow the components of the relaxation formulation to be inhaled directly into the lungs of a person. Other delivery systems include an aqueous sublingual spray and a beverage.

摘要翻译： 构成诱导人的深度放松状态的松弛制剂包括色氨酸，褪黑素，维生素B3和维生素B6的量。 另一种松弛制剂还包括一定量的酪氨酸，而另一种制剂包含一定量的维生素B12。 松弛配方的至少一个实施方案包括生理有效量的γ-氨基丁酸（“GABA”）。 提供递送系统以便于向个人管理放松配方。 递送系统可以包括可食用的高碳水化合物基质，例如巧克力巧克力。 或者，递送系统可以包括惰性可汽化化合物，以使松弛制剂的组分直接吸入人的肺部。 其他递送系统包括舌下水喷雾和饮料。

公开(公告)号：US20120010291A1

公开(公告)日：2012-01-12

申请号：US12811623

申请日：2009-08-12

申请人： Bruce W. Kneller

发明人： Bruce W. Kneller

IPC分类号： A61K31/198 ,  A61P17/00 ,  A61P21/00 ,  C07C251/02 ,  C07C249/02

CPC分类号： C07C279/14 ,  A23K20/142 ,  A23K50/20 ,  A23K50/40 ,  A23L33/175 ,  A23V2002/00 ,  A61K31/197 ,  C07C229/08 ,  A23V2250/306 ,  A23V2200/33 ,  A23V2200/316 ,  A23V2250/0628 ,  A23V2250/0612 ,  A23V2250/314 ,  A23V2250/0644 ,  A23V2250/062 ,  A23V2250/0652 ,  A23V2250/506 ,  A23V2250/636 ,  A23V2250/061

摘要： Disclosed are creatine β-alaninate, compositions and formulations containing same, and methods of use therefor.

摘要翻译： 公开的是肌酸和布拉宁，含有其的组合物和制剂及其使用方法。

公开(公告)号：US07601369B2

公开(公告)日：2009-10-13

申请号：US11713907

申请日：2007-03-05

申请人： William Shell ,  Elizabeth Charuvastra

发明人： William Shell ,  Elizabeth Charuvastra

IPC分类号： A61K36/25 ,  A61K36/258 ,  A61K36/16 ,  A61K36/54 ,  A61K36/734 ,  A61K31/221 ,  A61K36/00

CPC分类号： A61K31/522 ,  A23L33/105 ,  A23V2002/00 ,  A61K36/16 ,  A61K36/185 ,  A61K36/258 ,  A61K36/28 ,  A61K36/38 ,  A61K36/54 ,  A61K36/734 ,  A61K45/06 ,  A61K2300/00 ,  A23V2250/2108 ,  A23V2250/0624 ,  A23V2250/0652 ,  A23V2250/2122 ,  A23V2250/304 ,  A23V2250/0618 ,  A23V2250/2106

摘要： This invention describes a method and composition to enhance the synthesis and release of the neurotransmitters by the oral administration of neurotransmitter precursors, along with natural plant substances that stimulate uptake of the neurotransmitters precursors, while adding natural plant substances that activate adenylate cyclase in order to avoid attenuation and prevent pharmacologic tolerance. The invention describes compositions for a medical foods that are designed to improve cognitive function, induced sleep, a improve Parasympathetic function, improve autonomic balance, increase nitric oxide production, reduce blood pressure, increase blood flow, and treat virus infections. The compositions include amino acids such as choline, herbs such ginkgo biloba, and other foods such as coca. The invention also describes the use of physiologic tests such as 24 hour ECG monitoring to create the appropriate combinations and assess the useful proportions.

公开(公告)号：US07585523B2

公开(公告)日：2009-09-08

申请号：US10228765

申请日：2002-08-27

申请人： William Shell ,  Elizabeth Charuvastra

发明人： William Shell ,  Elizabeth Charuvastra

IPC分类号： A01N65/00 ,  A61K31/221 ,  A61K36/258 ,  A61K36/54 ,  A61K36/734 ,  A61K36/254 ,  A61K36/73

CPC分类号： A61K31/522 ,  A23L33/105 ,  A23V2002/00 ,  A61K36/16 ,  A61K36/185 ,  A61K36/258 ,  A61K36/28 ,  A61K36/38 ,  A61K36/54 ,  A61K36/734 ,  A61K45/06 ,  A61K2300/00 ,  A23V2250/2108 ,  A23V2250/0624 ,  A23V2250/0652 ,  A23V2250/2122 ,  A23V2250/304 ,  A23V2250/0618 ,  A23V2250/2106

摘要： A method and composition to enhance the synthesis and release of the neurotransmitters by the oral administration of neurotransmitter precursors, along with natural plant substances that stimulate uptake of the neurotransmitters precursors, while adding natural plant substances that activate adenylate cyclase in order to avoid attenuation and prevent pharmacologic tolerance. The compositions for medical foods are designed to improve cognitive function, induced sleep, improve Parasympathetic function, improve autonomic balance, increase nitric oxide production, reduce blood pressure, increase blood flow, and treat virus infections. The compositions include amino acids such as choline, herbs such ginkgo biloba, and other foods such as cocoa. The method uses physiologic tests such as 24 hour ECG monitoring to create the appropriate combinations and assess the useful proportions.

摘要翻译： 通过口服施用神经递质前体以及刺激神经递质前体摄取的天然植物物质，同时加入激活腺苷酸环化酶的天然植物物质以避免衰减和预防，从而增强神经递质的合成和释放的方法和组合物 药理耐受性。 旨在改善认知功能，诱导睡眠，改善副交感神经功能，改善自主神经平衡，增加一氧化氮产生，降低血压，增加血流量，治疗病毒感染。 组合物包括氨基酸，例如胆碱，草本银杏，以及其它食物如可可。 该方法使用诸如24小时ECG监测的生理测试来创建适当的组合并评估有用的比例。