摘要:
Systems, methods and kits relating to in-situ forming polymer foams for the treatment of aneurysms or fluid filled spaces are disclosed. The systems include an insertable medical device and an in-situ forming foam of lava like materials with a fast forming outer skin and a slower hardening interior that is formed from a one-, two- or multi-part formulation. When used to treat an aneurysm, the foam is placed into contact with at least a portion of an exterior surface of the medical device and/or the tissue surface of the aneurysm.
摘要:
Systems, methods and kits relating to in-situ forming polymer foams for the treatment of aneurysms or fluid filled spaces are disclosed. The systems include an insertable medical device and an in-situ forming foam of lava like materials with a fast forming outer skin and a slower hardening interior that is formed from a one-, two- or multi-part formulation. When used to treat an aneurysm, the foam is placed into contact with at least a portion of an exterior surface of the medical device and/or the tissue surface of the aneurysm.
摘要:
Systems and method for treating aneurysms are provided which utilize formulations that form polymer foams in situ. The formulations generally have a buoyancy greater than or less than blood, and either float to the top of the aneurysm and foam from the top down or sink to the bottom and foam from the bottom up.
摘要:
According to one aspect of the invention, multicomponent fiber are provided, which comprise (a) a polymeric core that comprises a core-forming polymer and (b) a polymeric sheath that comprises a sheath-forming polymer that is different than the core-forming polymer. Examples of core-forming polymers include, for instance, crosslinked polysiloxanes and thermoplastic polymers, among others. Examples of sheath-forming polymers include, for instance, solvent-soluble polymers, degradable polymers and hydrogel-forming polymers, among others. Other aspects of the present invention pertain to methods of forming such multicomponent fibers. For example, in certain preferred embodiments, the multicomponent fibers are formed using coaxial electrospinning techniques. Still other aspects of the present invention pertain to meshes and other articles that are formed using the multicomponent fibers.
摘要:
In various aspects, present disclosure is directed to methods, devices and systems whereby one or more low viscosity fluids may be introduced into a catheter and whereby the one or more low viscosity fluids may be converted into a high viscosity fluid in the catheter, which high viscosity fluid may be delivered from an exit port of the catheter.