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1.发明授权公开(公告)号：US08328749B2
公开(公告)日：2012-12-11
申请号：US11548499
申请日：2006-10-11
申请人： Tomoya Murakami , Masahiro Toyoda , Yoshihiro Mori
发明人： Tomoya Murakami , Masahiro Toyoda , Yoshihiro Mori
CPC分类号： A61M1/36 , A61M1/3612 , A61M1/3658 , A61M2230/207
摘要： A blood purification apparatus includes a blood circuit having arterial and venous blood circuits, a blood pump, a blood purifying device, an indicator applying device that applies a predetermined indicator to the blood flowing extracorporeally through the blood circuit, a detecting device that detects the indicator applied by the indicator applying device, an arithmetic device that calculates, based on the indicator detected by the detecting device, a recirculation rate, and a calculating device that calculates an ideal extracorporeally circulating blood flow that results in the recirculation rate being no more than a predetermined value when the recirculation rate calculated by the arithmetic device is greater than the predetermined value. The recirculation rate is a proportion of a recirculated blood flow, which is reintroduced to the patient from the venous blood circuit and directed again to the arterial blood circuit, relative to an extracorporeally circulating blood flow.
摘要翻译： 一种血液净化装置，包括具有动脉和静脉血液循环的血液回路，血液泵，血液净化装置，对体外通过血液循环流动的血液施加规定的指示器的指示器施加装置，检测指示器 由所述指示剂施加装置施加的运算装置，基于由所述检测装置检测出的指标计算再循环率的运算装置，以及计算将所述再循环率不大于1的理想的体外循环血流的计算装置 当由运算装置计算的再循环速率大于预定值时的预定值。 再循环率是再循环血流量的一部分，再循环血流从静脉血回路重新引入患者，并相对于体外循环的血流再次引导到动脉血回路。
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公开(公告)号：US07537688B2
公开(公告)日：2009-05-26
申请号：US11209278
申请日：2005-08-22
CPC分类号： A61M1/3621 , A61M1/16 , A61M1/361 , A61M1/3612 , A61M1/3658
摘要： A blood purification device confirms whether a specific peak is provided by e.g. an ultrafiltration pump, to concentrate the blood or not and also accurately measures a blood re-circulation with a minimum of parameters providing a ratio of re-circulating blood. The blood purification device composed of arterial blood circuit route 1a and venous blood circuit route 1b, blood pump 3, dialyzer 2, water removal pump 8 providing the specific peak in the variation of blood concentration by removing water rapidly, and a detector detecting the specific peak, can measure the blood re-circulation thereby. The re-circulating blood flowing is the blood which was introduced again to arterial blood circuit route 1a after it had been returned to a patient from venous blood circuit route 1b. A first detector 5a installed in the arterial blood circuit route 1a and a second detector 5b installed in venous blood circuit route detector.
摘要翻译： 血液净化装置确认是否由特定的峰提供。 超滤泵，以集中血液或不精确，并且以最小的参数精确地测量血液循环，提供再循环血液的比例。 血液净化装置由动脉血液路径1a和静脉血液回路1b，血液泵3，透析器2，除水泵8构成，通过快速除去水而提供血液浓度变化的特定峰值，以及检测器 峰值，可以测量血液循环。 再循环血液流动是在从静脉血液回路1b返回给患者之后再次引入动脉血液回路1a的血液。 安装在动脉血液路径1a中的第一检测器5a和安装在静脉血液路径检测器中的第二检测器5b。
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3.发明申请公开(公告)号：US20070083145A1
公开(公告)日：2007-04-12
申请号：US11548499
申请日：2006-10-11
申请人： Tomoya Murakami , Masahiro Toyoda , Yoshihiro Mori
发明人： Tomoya Murakami , Masahiro Toyoda , Yoshihiro Mori
IPC分类号： A61M37/00
CPC分类号： A61M1/36 , A61M1/3612 , A61M1/3658 , A61M2230/207
摘要： A blood purification apparatus includes a blood circuit having arterial and venous blood circuits, a blood pump, a blood purifying device, an indicator applying device that applies a predetermined indicator to the blood flowing extracorporeally through the blood circuit, a detecting device that detects the indicator applied by the indicator applying device, an arithmetic device that calculates, based on the indicator detected by the detecting device, a recirculation rate, and a calculating device that calculates an ideal extracorporeally circulating blood flow that results in the recirculation rate being no more than a predetermined value when the recirculation rate calculated by the arithmetic device is greater than the predetermined value. The recirculation rate is a proportion of a recirculated blood flow, which is reintroduced to the patient from the venous blood circuit and directed again to the arterial blood circuit, relative to an extracorporeally circulating blood flow.
摘要翻译： 一种血液净化装置，包括具有动脉和静脉血液循环的血液回路，血液泵，血液净化装置，对体外通过血液循环流动的血液施加规定的指示器的指示器施加装置，检测指示器 由所述指示剂施加装置施加的运算装置，基于由所述检测装置检测出的指标计算再循环率的运算装置，以及计算将所述再循环率不大于1的理想的体外循环血流的计算装置 当由运算装置计算的再循环速率大于预定值时的预定值。 再循环率是再循环血流量的一部分，再循环血流从静脉血回路重新引入患者，并相对于体外循环的血流再次引导到动脉血回路。
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公开(公告)号：US20060043007A1
公开(公告)日：2006-03-02
申请号：US11209278
申请日：2005-08-22
IPC分类号： B01D61/30
CPC分类号： A61M1/3621 , A61M1/16 , A61M1/361 , A61M1/3612 , A61M1/3658
摘要： A blood purification device allows confirming whether a specific peak is provided by a means, such as a ultrafiltration pump, to concentrate the blood or not and also allows measuring certainly and accurately a blood re-circulation with reduction of parameters which can provide a ratio of re-circulating blood. The blood purification device including blood circuit route 1 composed of arterial blood circuit route 1a and venous blood circuit route 1b, blood pump 3, dialyzer 2, water removal pump 8 which can provide the specific peak in the variation of blood concentration by removing water rapidly in a short period of time, and detecting means detecting said specific peak, can measure the blood re-circulation based on the specific peak detected by the detecting means. The re-circulating blood flowing is the blood which was introduced again to arterial blood circuit route 1a after it had been returned to a patient from venous blood circuit route 1b. The detecting means includes first detecting means 5a installed in arterial blood circuit route 1a and second detecting means 5b installed in venous blood circuit route 1b.
摘要翻译： 血液净化装置允许通过诸如超滤泵的装置来确定特定峰值是否提供浓缩血液，并且还允许通过降低参数来确定地和准确地测量血液循环，所述参数可以提供比例 再循环血液 血液净化装置，包括由动脉血液路径1a和静脉血液回路1b构成的血液路径1，血液泵3，透析器2，除水泵8，其可以通过除去血液浓度变化来提供特定峰值 并且检测所述特定峰值的检测装置可以基于由检测装置检测到的特定峰值来测量血液循环。 再循环血液流动是在从静脉血液回路1B返回给患者之后再次引入动脉血液回路1a的血液。 检测装置包括安装在静脉血液回路1a中的第一检测装置5a和安装在静脉血液回路1B中的第二检测装置5b。
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公开(公告)号：US07931610B2
公开(公告)日：2011-04-26
申请号：US12174742
申请日：2008-07-17
申请人： Tomoya Murakami , Masahiro Toyoda , Akari Agata
发明人： Tomoya Murakami , Masahiro Toyoda , Akari Agata
CPC分类号： A61M1/3653 , A61M1/361 , A61M1/3612 , A61M1/3658
摘要： A blood purification apparatus that can make the specific peak to be imparted to the blood more distinct, and therefore can detect blood recirculation reliably and precisely, is presented. It contains a blood circuit route, a blood pump, a dialyzer, dialysate introduction and discharge lines, a duplex pump, a pressurizing pump, a blood concentration means, and detection means that detect the specific peak imparted by the blood concentration means. The blood concentration means is configured to have an atmosphere release line, the tip of which is open to the atmosphere, that extends from between the pressurizing pump and the duplex pump in the dialysate discharge line, and to have an electromagnetic valve that can open or close the atmosphere release line. The electromagnetic valve opens the atmosphere release line to impart the specific peak by rapidly concentrating the blood flowing in the dialyzer for a short period of time.
摘要翻译： 可以使血液净化装置能够使特定的峰值赋予血液更加清晰，因此可以可靠且精确地检测血液循环。 它包含血液回路，血液泵，透析器，透析液引入和排出管线，双相泵，加压泵，血液浓缩装置和检测由血液浓度装置赋予的特定峰值的检测装置。 血液浓度装置被配置为具有气体释放管线，其顶端向大气开放，其从透析液排出管线中的加压泵和双相泵之间延伸，并且具有能够打开的电磁阀或 关闭气氛释放线。 电磁阀打开大气释放线，以通过快速浓缩在透析器中流动的血液短时间来赋予特定峰值。
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公开(公告)号：US20080103427A1
公开(公告)日：2008-05-01
申请号：US11863493
申请日：2007-09-28
申请人： Masahiro Toyoda , Tomoya Murakami
发明人： Masahiro Toyoda , Tomoya Murakami
IPC分类号： A61M1/14
CPC分类号： A61M1/16 , A61M1/1613 , A61M1/3609 , A61M1/361 , A61M1/3612 , A61M1/3658 , A61M2205/3313 , A61M2205/50 , A61M2230/207
摘要： A blood purification device capable of performing an ideal blood purification treatment which accounts for blood recirculation is provided. That is, a blood purification device is furnished with a blood circuit containing an arterial blood circuit and a venous blood circuit for circulating blood outside the body, a dialyzer for purifying blood flowing in the blood circuit, hematocrit sensors for measuring the hematocrit value of blood circulating outside the body in the blood circuit, and a recirculation rate derivation means for obtaining a recirculation rate, and further provided with a true value derivation means for obtaining a patient's true hematocrit value based on the recirculation rate obtained by the recirculation rate derivation means.
摘要翻译： 提供能够进行考虑血液再循环的理想的血液净化处理的血液净化装置。 也就是说，血液净化装置配备有包含动脉血回路的血液回路和用于使体外循环血液的静脉血回路，用于净化血液回路中流动的血液的透析器，用于测量血液的血细胞比容值的血细胞比容传感器 在血液循环体外循环，以及用于获得再循环率的再循环速率导出装置，并且还具有真值推定装置，用于根据再循环速率导出装置获得的再循环速度获得患者的真实血细胞比容值。
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公开(公告)号：US20090054822A1
公开(公告)日：2009-02-26
申请号：US12174742
申请日：2008-07-17
申请人： Tomoya Murakami , Masahiro Toyoda , Akari Agata
发明人： Tomoya Murakami , Masahiro Toyoda , Akari Agata
IPC分类号： A61M1/14
CPC分类号： A61M1/3653 , A61M1/361 , A61M1/3612 , A61M1/3658
摘要： A blood purification apparatus that can make the specific peak to be imparted to the blood more distinct, and therefore can detect blood recirculation reliably and precisely, is presented. It contains a blood circuit route, a blood pump, a dialyzer, dialysate introduction and discharge lines, a duplex pump, a pressurizing pump, a blood concentration means, and detection means that detect the specific peak imparted by the blood concentration means. The blood concentration means is configured to have an atmosphere release line, the tip of which is open to the atmosphere, that extends from between the pressurizing pump and the duplex pump in the dialysate discharge line, and to have an electromagnetic valve that can open or close the atmosphere release line. The electromagnetic valve opens the atmosphere release line to impart the specific peak by rapidly concentrating the blood flowing in the dialyzer for a short period of time.
摘要翻译： 可以使血液净化装置能够使特定的峰值赋予血液更加清晰，因此可以可靠且精确地检测血液循环。 它包含血液回路，血液泵，透析器，透析液引入和排出管线，双相泵，加压泵，血液浓缩装置和检测由血液浓度装置赋予的特定峰值的检测装置。 血液浓度装置被配置为具有气体释放管线，其顶端向大气开放，其从透析液排出管线中的加压泵和双相泵之间延伸，并且具有能够打开的电磁阀或 关闭气氛释放线。 电磁阀打开大气释放线，以通过快速浓缩在透析器中流动的血液短时间来赋予特定峰值。
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公开(公告)号：US10179382B2
公开(公告)日：2019-01-15
申请号：US13980537
申请日：2011-02-15
申请人： Masaaki Miyazaki , Tomoya Murakami
发明人： Masaaki Miyazaki , Tomoya Murakami
摘要： A pallet transport system of a machine tool promoting transport of a pallet for workpiece mounting use from a first stand to an adjoining second stand, wherein the first stand has a first mounting part which defines a first mounting surface, the second stand has a second mounting part which defines a second mounting surface, and the pallet has a mounted part attachable to the first and second mounting parts, along a transport direction of the pallet, includes a support mechanism turnably supporting at least one of the first stand, the second stand, and the pallet so that the orientations of a mounted surface defined by the mounted part and the second mounting surface match due to contact force between the mounted part and the second mounting part along with transport of the pallet from the first stand to the second stand along the first mounting surface.
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9.发明申请ERROR CORRECTION FOR A LIQUID CONCENTRATION DETECTOR OF A BLOOD PURIFICATION APPARATUS 有权血液净化装置的液体浓度检测器的错误校正公开(公告)号：US20110139690A1
公开(公告)日：2011-06-16
申请号：US12967562
申请日：2010-12-14
IPC分类号： A61M1/36
CPC分类号： A61M1/367 , A61M1/1692 , A61M2205/3306 , G01N21/05 , G01N21/274 , G01N21/59 , G01N2201/062 , G01N2201/0621
摘要： A blood purification instrument for extracorporeally circulating a patient's blood and a concentration detector detects a concentration of liquid during blood purification wherein the concentration detector has a light emitter irradiating light onto the liquid, a light receiver receives the light as transmitted through the liquid, a reference light receiver receives reference light branched from the light emitter without transmission through the liquid, and a detector detecting the light intensity respectively of the transmitted light and the reference light received by the light receiver and the reference light receiver, respectively. The blood purification apparatus further includes an error corrector detecting the concentration of the liquid based on the received light intensity of the light received by the light receiver and detected by the detector and for correcting a detected error of the concentration detector based on the received light intensity of the reference light received by the reference light receiver.
摘要翻译： 用于体外循环患者血液的血液净化装置和浓度检测器检测血液净化期间的液体浓度，其中浓度检测器具有将发光体照射到液体上的发光体，光接收器接收透过液体的光，参考 光接收器接收从光发射器分支的参考光，而不透射通过液体;检测器分别检测由光接收器和参考光接收器接收的透射光和参考光的光强度。 血液净化装置还包括误差校正器，其基于由光接收器接收并由检测器检测到的光的接收光强度来检测液体的浓度，并且用于基于接收的光强度校正浓度检测器的检测误差 由参考光接收器接收的参考光。
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公开(公告)号：US20130302128A1
公开(公告)日：2013-11-14
申请号：US13980537
申请日：2011-02-15
申请人： Masaaki Miyazaki , Tomoya Murakami
发明人： Masaaki Miyazaki , Tomoya Murakami
IPC分类号： B23Q7/00
CPC分类号： B23Q7/00 , B23Q3/186 , B23Q7/1426 , Y10T29/5196
摘要： A pallet transport system of a machine tool promoting transport of a pallet for workpiece mounting use from a first stand to an adjoining second stand, wherein the first stand has a first mounting part which defines a first mounting surface, the second stand has a second mounting part which defines a second mounting surface, and the pallet has a mounted part attachable to the first and second mounting parts, along a transport direction of the pallet, includes a support mechanism turnably supporting at least one of the first stand, the second stand, and the pallet so that the orientations of a mounted surface defined by the mounted part and the second mounting surface match due to contact force between the mounted part and the second mounting part along with transport of the pallet from the first stand to the second stand along the first mounting surface.
摘要翻译： 一种用于促进从第一支架到相邻的第二支架的用于工件安装使用的托盘的托盘输送系统，其中所述第一支架具有限定第一安装表面的第一安装部分，所述第二支架具有第二安装 该部分限定第二安装表面，并且托盘具有可沿着托盘的输送方向附接到第一和第二安装部分的安装部分，包括可转动地支撑第一支架，第二支架， 以及托盘，使得由安装部分和第二安装表面限定的安装表面的方位由于安装部件和第二安装部件之间的接触力而匹配，同时托盘从第一支架传送到第二支架 第一个安装面。
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