公开(公告)号：US20200255370A1

公开(公告)日：2020-08-13

申请号：US16651987

申请日：2018-09-21

申请人： AK CHEMTECH CO., LTD.

发明人： Byung Jo KIM ,  Ki Ho PARK ,  Hyon Pil YU ,  Ji Hye BAE ,  Song Yi KIM

IPC分类号： C07C227/28 ,  C11D1/10 ,  C07C227/40

摘要： The present invention relates to a method for preparing a glutamate-based surfactant. More specifically, the present invention provides a method for preparing a glutamate-based surfactant, the method being very economical and being capable of mass production of the glutamate-based surfactant.

公开(公告)号：US10428359B2

公开(公告)日：2019-10-01

申请号：US15717042

申请日：2017-09-27

申请人： AJINOMOTO CO., INC.

发明人： Mika Moriya ,  Kazuyuki Hayashi ,  Akari Yokokawa

IPC分类号： C12P13/20 ,  C07C227/28 ,  C12P13/08 ,  C12P13/14 ,  C07K14/34 ,  C12N9/88 ,  C07C229/36 ,  C12N1/20 ,  C12N15/66 ,  C12Q1/686

摘要： A method for producing an L-amino acid such as L-glutamic acid is provided. An L-amino acid is produced by culturing a bacterium having an L-amino acid-producing ability, which has been modified so that the activity of a C4-dicarboxylic acid-uptake carrier such as DctA, DcuA, and DcuB is increased, in a medium, and collecting the L-amino acid from the medium or cells of the bacterium.

公开(公告)号：US08927746B2

公开(公告)日：2015-01-06

申请号：US14129675

申请日：2012-07-10

申请人： Jean-Luc Dubois

发明人： Jean-Luc Dubois

IPC分类号： C07B43/00 ,  C07C51/36 ,  C07C51/09 ,  C07C227/28 ,  C07C227/16 ,  C07C253/22 ,  C07C229/08 ,  C07C253/30 ,  C07C51/285 ,  C07C51/34 ,  C07C255/07 ,  C07C51/377

CPC分类号： C07C227/28 ,  C07C51/09 ,  C07C51/285 ,  C07C51/34 ,  C07C51/36 ,  C07C51/377 ,  C07C227/16 ,  C07C229/08 ,  C07C253/22 ,  C07C253/30 ,  C07C255/07 ,  C07C255/19 ,  C07C53/126 ,  C07C57/12 ,  C07C59/01 ,  C07C55/02

摘要： The subject matter of the invention is a process for synthesizing ω-functionalized acids of formula R—(CH2)n—COOH in which R is COOH or NH2CH2, from a feedstock of natural origin containing hydroxylated fatty acids.

摘要翻译： 本发明的主题是从含有羟基化脂肪酸的天然来源的原料合成其中R为COOH或NH 2 CH 2的式R-（CH 2）n -COOH的ω官能化酸的方法。

公开(公告)号：US6099654A

公开(公告)日：2000-08-08

申请号：US367690

申请日：1999-08-19

申请人： Kikuzo Kaneko ,  Takayuki Masuda ,  Fumihiko Matsuda ,  Kohei Sato ,  Kouji Tanikawa

发明人： Kikuzo Kaneko ,  Takayuki Masuda ,  Fumihiko Matsuda ,  Kohei Sato ,  Kouji Tanikawa

IPC分类号： B01D15/08 ,  C07C227/28 ,  C07C227/40 ,  C07C227/42 ,  C07C229/02 ,  C07C229/12 ,  G01N30/46 ,  G01N30/88 ,  C07B63/00

CPC分类号： C07C227/42 ,  C07C227/28

摘要： A starting solution material in the form of waste produced in the course of separation and recovery of sucrose from sugar beet extract or sugar beet molasses with a 2-component separation simulated moving bed chromatographic separator (using a strongly acidic cation exchange resin in a salt form as chromatographic packing) or its concentrate is used to separate therefrom a crude betaine fraction with a 2-component separation simulated moving bed chromatographic separator using as chromatographic packing a strongly acidic cation exchange resin in an ionic form equilibrated with that of the starting solution material. The crude betaine fraction or its concentrate is used to separate therefrom a betaine fraction with a 2-component separation simulated moving bed chromatographic separator using as chromatographic packing a strongly acidic cation exchange resin having at least 10% (based on the ion exchange capacity) of the ionic form thereof changed to the Ca form. The betaine fraction may be concentrated and subjected to crystallization, whereby high-purity betaine can be obtained.

摘要翻译： PCT No.PCT / JP98 / 05843 Sec。 371日期1999年8月19日 102（e）1999年8月19日PCT 1998年12月24日PCT PCT。 出版物WO99 /​​ 33784 日期1999年7月8日在使用2-组分分离模拟移动床色谱分离器（使用强酸性阳离子交换器）从甜菜提取物或甜菜糖蜜分离和回收蔗糖过程中产生的废物形式的起始溶液材料 树脂为盐形式作为色谱填充）或其浓缩物用于将粗制甜菜碱部分与2-组分分离模拟移动床层析分离器分离，使用与酸性阳离子交换树脂平衡的离子形式的强酸性阳离子交换树脂 起始溶液材料。 使用粗制甜菜碱级分或其浓缩物将其与2-组分分离模拟移动床层析分离器的甜菜碱级分分离，使用色谱填料将具有至少10％（基于离子交换容量）的强酸性阳离子交换树脂 其离子形式变为Ca形式。 可以将甜菜碱级分浓缩并进行结晶，由此可以获得高纯度的甜菜碱。

公开(公告)号：US5049279A

公开(公告)日：1991-09-17

申请号：US348074

申请日：1989-05-05

申请人： Marie-Christine Bitar ,  Jean-Louis Sabot ,  Paul Aviron-Viollet

发明人： Marie-Christine Bitar ,  Jean-Louis Sabot ,  Paul Aviron-Viollet

IPC分类号： C07B63/00 ,  B01D11/04 ,  C07B31/00 ,  C07C20060101 ,  C07C67/00 ,  C07C227/00 ,  C07C227/28 ,  C07C227/40 ,  C07C229/02 ,  C07C239/00 ,  C07C279/04 ,  C07C279/14 ,  C07C313/00 ,  C07C319/28 ,  C07C323/58 ,  C07D207/16 ,  C07D233/64

CPC分类号： C07C227/40

摘要： Desired amino acids, e.g., phenylalanine, arginine, leucine, isoleucine, valine and/or histidine, are selectively countercurrently extracted from more complex, essentially cystine-free solutions of a plurality of amino acids, utilizing an organic phosphorus acid extractant, advantageously in solution in at least one alcohol, ether, ketone and/or aliphatic hydrocarbon.

摘要翻译： 选择性氨基酸，例如苯丙氨酸，精氨酸，亮氨酸，异亮氨酸，缬氨酸和/或组氨酸，通过使用有机磷酸萃取剂，有利地在溶液中从更复杂的，基本上不含有胱氨酸的多个氨基酸的溶液中选择性逆流提取 在至少一种醇，醚，酮和/或脂族烃中。

公开(公告)号：US4874893A

公开(公告)日：1989-10-17

申请号：US133045

申请日：1988-01-27

申请人： Michel Flork

发明人： Michel Flork

IPC分类号： C07C229/00 ,  B01J27/02 ,  C07B61/00 ,  C07C67/00 ,  C07C227/00 ,  C07C227/02 ,  C07C227/18 ,  C07C227/28 ,  C07C229/02 ,  C07D207/16 ,  C07D233/64 ,  C12P7/40

CPC分类号： C07C227/28

摘要： Process for the preparation of amino acids by hydrolysis of proteins such as pig bristles. Said process comprises the charging into a vat of a solution of sulphuric acid at least 12N, heating the solution to at least 100.degree. C., adding simultaneously the proteins to be hydrolyzed and a complementary amount of sulphuric acid corresponding to the neutralization of the amine functions of the amino acids, maintaining the hydrolysis conditions in 12N medium and at 100.degree. C., stopping the reaction by addition of water and removing the acid in excess. Thereby, a mixture of amino acids is obtained with a good yield and without degradation.

摘要翻译： PCT No.PCT / FR87 / 00094 Sec。 371日期：1988年1月27日 102（e）日期1988年1月27日PCT提交1987年3月26日PCT公布。 公开号WO87 / 05895 日期1987年10月8日。通过水解蛋白质例如猪鬃毛来制备氨基酸的方法。 所述方法包括将至少12N的硫酸溶液装入槽中，将溶液加热到至少100℃，同时加入待水解的蛋白质和相应于胺中和的互补量的硫酸 氨基酸的功能，在12N培养基和100℃保持水解条件，通过加入水停止反应并除去过量的酸。 由此，可以获得良好的收率而不降解的氨基酸混合物。

公开(公告)号：US4714767A

公开(公告)日：1987-12-22

申请号：US753881

申请日：1985-07-11

申请人： Kiyoshi Tanaka ,  Masaru Saeki ,  Tsutomu Matsuishi ,  Yoshihiro Koga ,  Tetsuya Kawakita

发明人： Kiyoshi Tanaka ,  Masaru Saeki ,  Tsutomu Matsuishi ,  Yoshihiro Koga ,  Tetsuya Kawakita

IPC分类号： B01J39/04 ,  B01J47/00 ,  C07C67/00 ,  C07C227/00 ,  C07C227/28 ,  C07C227/40 ,  C07C229/26 ,  C07D233/64 ,  C12P13/04 ,  C12P13/08 ,  C07C101/24

CPC分类号： C12P13/08 ,  B01J47/003 ,  C12P13/04

摘要： A process for separating basic amino acids from a liquid containing the same using cation exchange resin towers in series, which comprises effecting repetitive adsorption and elution steps in sequence, wherein the washing water employed in said adsorption and elution steps is obtained by recycling the latter portion of a liquid discharged from a first tower of the adsorption step into an adsorption step in a subsequent cycle, or by recycling a liquid discharged from a first tower at the elution step into an elution step in a subsequent cycle.

摘要翻译： 一种使用阳离子交换树脂塔串联分离碱性氨基酸的方法，其包括依次进行重复吸附和洗脱步骤，其中用于所述吸附和洗脱步骤的洗涤水通过再循环后一部分 从吸附步骤的第一塔排出的液体在随后的循环中进入吸附步骤，或者在洗脱步骤中将从第一塔排出的液体再循环到随后的循环中的洗脱步骤。

公开(公告)号：US4675196A

公开(公告)日：1987-06-23

申请号：US584520

申请日：1984-02-28

申请人： Carlo Villa ,  Alvise P. G. Vecchiolino ,  Alberto Mangia

发明人： Carlo Villa ,  Alvise P. G. Vecchiolino ,  Alberto Mangia

IPC分类号： A61K35/54 ,  A23J3/10 ,  A23J3/30 ,  A61K35/60 ,  A61K36/00 ,  A61K36/48 ,  A61K36/81 ,  A61K36/899 ,  A61K38/00 ,  C07C67/00 ,  C07C227/00 ,  C07C227/28 ,  C07C227/40 ,  C07C229/24 ,  C07K1/18 ,  C07K14/00 ,  A23C9/14 ,  C07C99/12 ,  C07C101/22 ,  C12H1/04

CPC分类号： A23J3/10 ,  A23J3/30 ,  Y10S514/893 ,  Y10S514/921

摘要： A process for the total or partial elimination of aspartic acid and glutamic acid from a protein hydrolyzate or a mixture of aminoacids is described, which consists of passing the hydrolyzate or mixture of aminoacids in solution on an anion exchange resin and then washing with water or eluting the aminoacids from the resin. Aspartic acid and glutamic acid are at least partially separated from the other aminoacids because of their affinity for the resin which is greater than the affinity of the other aminoacids. The resulting mixtures of aminoacids may be used as such or may be further adjusted by addition of valine, leucine, isoleucine, and arginine to give products valuable in clinical nutrition.

摘要翻译： 描述了从蛋白质水解产物或氨基酸混合物中全部或部分地消除天冬氨酸和谷氨酸的方法，其包括将溶液中的水解产物或氨基酸的混合物通过阴离子交换树脂，然后用水洗脱或洗脱 来自树脂的氨基酸。 天冬氨酸和谷氨酸与其它氨基酸至少部分分离，因为它们对树脂的亲和力大于其它氨基酸的亲和力。 所得到的氨基酸混合物可以原样使用，也可以通过加入缬氨酸，亮氨酸，异亮氨酸和精氨酸来进一步调节，以提供在临床营养中有价值的产品。

公开(公告)号：US20210284932A1

公开(公告)日：2021-09-16

申请号：US17258952

申请日：2019-07-10

申请人： Clariant International Ltd.

发明人： Sushant Dattaram WADEKAR ,  Prerak Rajendrakumar CONTRACTOR

IPC分类号： C11D3/00 ,  C07C227/28 ,  C07C229/22 ,  C11D1/62

摘要： Esterquats find major applications as fabric softeners. After Tallow fatty acids and Palm oil fatty acids, fatty acids from sustainable sources like Rice bran fatty acids (RBFA) are desired. RBFA is formed as a by-product during refining of Rice bran oil and hence it is contained in the non edible portion of the oil. The production of high quality esterquats from this by-product is challenging, but the invention describes a process to produce high quality esterquats having low odour and a low acid value. This enhances easy formulation of various products and better customer acceptance. Liquid esterquats produced from RBFA enable e.g. cold processing for fabric softener formulations.

公开(公告)号：US20210145968A1

公开(公告)日：2021-05-20

申请号：US16645301

申请日：2018-09-05

申请人： TECHNICAL INSTITUTE OF PHYSICS AND CHEMISTRY OF THE CHINESE ACADEMY OF SCIENCES

发明人： Pengfei WANG ,  Jiasheng WU ,  Weimin LIU ,  Xiuli ZHENG ,  Ying GU

IPC分类号： A61K41/00 ,  C07C225/32 ,  C07C221/00 ,  A61K47/10 ,  C07C229/16 ,  C07C227/28 ,  C07C229/28 ,  C07C243/20 ,  C07C241/02 ,  C07D401/12 ,  C07D403/12 ,  C07D519/00 ,  C07D295/13 ,  C07D295/205 ,  C07C323/30 ,  C07C323/38

摘要： The present invention discloses a hypocrellin derivative substituted both in a peri-position and in a 2-position by an amino, and a preparation method and use thereof. A general structural formula of the derivative is as represented by formulas I-a to I-d: The hypocrellin derivative substituted both in a peri-position and in a 2-position by an amino prepared in the present invention has a maximum absorption wavelength of 600-650 nm and a molar extinction coefficient reaching about 20000-40000 M−1cm−1. Compared with unmodified hypocrellin or hypocrellin having only a 2-position modified, an absorption spectrum of the derivative is significantly red-shifted and the molar extinction coefficient is greatly improved, and the derivative can efficiently produce reactive oxygen species such as singlet oxygen in a photosensitive condition. In the same condition, the hypocrellin derivative substituted both in a peri-position and in a 2-position by an amino involved in the present invention, when used as a photosensitizer, has a stronger ability to photo-dynamically inactivate tumor cells than the first and second generation commercial photosensitizers.