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公开(公告)号：US20140080980A1
公开(公告)日：2014-03-20
申请号：US13622369
申请日：2012-09-19
IPC分类号： C08G69/48
CPC分类号： C08G73/028 , C08G83/004 , C08K3/042 , C08K5/3462 , C08K9/04 , C08L79/02 , C08L101/005
摘要： The present invention relates to a fluorescent hybrid material of dual functionality. The hybrid material may function as the fluorescence marker and as the attacking drug at the same time for biomedical applications.
摘要翻译： 本发明涉及双功能的荧光混合材料。 混合材料可以作为荧光标记物和作为攻击药物同时用作生物医学应用。
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公开(公告)号：US08927658B2
公开(公告)日：2015-01-06
申请号：US13622369
申请日：2012-09-19
CPC分类号： C08G73/028 , C08G83/004 , C08K3/042 , C08K5/3462 , C08K9/04 , C08L79/02 , C08L101/005
摘要： The present invention relates to a fluorescent hybrid material of dual functionality. The hybrid material may function as the fluorescence marker and as the attacking drug at the same time for biomedical applications.
摘要翻译： 本发明涉及双功能的荧光混合材料。 混合材料可以作为荧光标记物和作为攻击药物同时用作生物医学应用。
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3.发明授权Method for making carbon nanotube-loaded electrode, carbon nanotube-loaded electrode made by the method, and applications thereof 有权制造碳纳米管负载电极的方法，通过该方法制造的含碳纳米管的电极及其应用公开(公告)号：US09082528B2
公开(公告)日：2015-07-14
申请号：US13336326
申请日：2011-12-23
CPC分类号： H01B1/24 , B82Y30/00 , B82Y40/00 , C01B32/174 , H01M4/00 , H01M4/049 , H01M4/60 , H01M4/8647
摘要： The present invention provides a method for fabricating a carbon nanotube-loaded electrode enabling that hybrid carbon nanotubes comprising dendrimer-encapsulated metal nanoparticles covalently immobilized on carbon nanotubes via a first covalent bond are made and such hybrid carbon nanotubes are then covalently immobilized on a metal electrode coated with a self-assembled monolayer via a second covalent bond. Also provided is a carbon nanotube-loaded electrode made by the method. The electrode thus made possesses high durability, reactivity and stability.
摘要翻译： 本发明提供一种制造碳纳米管负载电极的方法，其使得能够使包含通过第一共价键共价固定在碳纳米管上的树枝状聚合物包封的金属纳米颗粒的混合碳纳米管被共价固定在金属电极上 通过第二共价键涂覆自组装单层。 还提供了通过该方法制造的负载碳纳米管的电极。 这样制成的电极具有高的耐久性，反应性和稳定性。
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4.发明申请METHOD FOR MAKING CARBON NANOTUBE-LOADED ELECTRODE, CARBON NANOTUBE-LOADED ELECTRODE MADE BY THE METHOD, AND APPLICATIONS THEREOF 有权用于制备碳纳米管负载电极的方法，通过该方法制备的碳纳米管负载的电极及其应用公开(公告)号：US20130161066A1
公开(公告)日：2013-06-27
申请号：US13336326
申请日：2011-12-23
CPC分类号： H01B1/24 , B82Y30/00 , B82Y40/00 , C01B32/174 , H01M4/00 , H01M4/049 , H01M4/60 , H01M4/8647
摘要： The present invention provides a method for fabricating a carbon nanotube-loaded electrode enabling that hybrid carbon nanotubes comprising dendrimer-encapsulated metal nanoparticles covalently immobilized on carbon nanotubes via a first covalent bond are made and such hybrid carbon nanotubes are then covalently immobilized on a metal electrode coated with a self-assembled monolayer via a second covalent bond. Also provided is a carbon nanotube-loaded electrode made by the method. The electrode thus made possesses high durability, reactivity and stability.
摘要翻译： 本发明提供一种制造碳纳米管负载电极的方法，其使得能够使包含通过第一共价键共价固定在碳纳米管上的树枝状聚合物包封的金属纳米颗粒的混合碳纳米管，然后将这种杂化碳纳米管共价固定在金属电极上 通过第二共价键涂覆自组装单层。 还提供了通过该方法制造的负载碳纳米管的电极。 这样制成的电极具有高的耐久性，反应性和稳定性。
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5.发明申请SUBSTRATE MIMICKING INTERCELLULAR LIPIDS IN STRATUM CORNEUM AND METHOD OF EVALUATING SKIN ROUGHENING USING THE SAME 有权基质金刚石中的纤维状细胞脂肪和使用其评估皮肤粗糙度的方法公开(公告)号：US20130000394A1
公开(公告)日：2013-01-03
申请号：US12998985
申请日：2009-09-01
申请人： Takuya Saiwaki , Takashi Oka , Yuichiro Mori , Toyoko Imae , Xiaojuan Wang , Masaki Ujihara
发明人： Takuya Saiwaki , Takashi Oka , Yuichiro Mori , Toyoko Imae , Xiaojuan Wang , Masaki Ujihara
CPC分类号： G01N33/92 , G01N2800/20 , Y10T436/104165
摘要： A substrate mimicking intercellular lipids in stratum corneum consisting of a substrate and a lipid membrane formed on the substrate, wherein the lipid membrane is formed from ceramide, palmitic acid and cholesterol, and the ceramide, palmitic acid and cholesterol are present at a mass ratio of 20-70%:10-600:20-40% (ceramide:palmitic acid:cholesterol).
摘要翻译： 在基质上形成的由底物和脂质膜构成的角质层中的模拟细胞间脂质的底物，其中脂质膜由神经酰胺，棕榈酸和胆固醇形成，神经酰胺，棕榈酸和胆固醇以质量比 20-70％：10-600:20-40％（神经酰胺：棕榈酸：胆固醇）。
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6.发明申请BIOCOMPARTIPLE CONFEITO-LIKE GOLD NANOPARTICLES, METHOD FOR MAKING THE SAME, AND THEIR BIOMEDICAL APPLICATIONS 有权生物相容性类似金纳米颗粒，其制备方法及其生物医学应用公开(公告)号：US20130164842A1
公开(公告)日：2013-06-27
申请号：US13333868
申请日：2011-12-21
申请人： Masaki Ujihara , Toyoko Imae
发明人： Masaki Ujihara , Toyoko Imae
CPC分类号： B22F9/24 , A61K41/0052 , B22F1/0018 , B22F1/0062 , B22F2001/0033 , B82Y5/00 , B82Y30/00 , C12N5/10 , C22C5/02 , Y10T428/12014
摘要： The present invention provides a method for producing gold nanoparticles using hydroxyl peroxide in an aqueous alkaline condition in the presence of a biocompatible protecting agent. The method of the invention does not involve toxic reagents and therefore are environmentally friendly. The gold nanoparticles thus produced can be used in biomedical applications including cancer therapy and drug delivery without purification.
摘要翻译： 本发明提供了在生物相容性保护剂存在下，在含水碱性条件下使用羟基过氧化物制备金纳米颗粒的方法。 本发明的方法不涉及有毒试剂，因此是环境友好的。 如此生产的金纳米颗粒可用于生物医学应用，包括癌症治疗和药物递送，无需纯化。
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7.发明授权Biocompatible confeito-like gold nanoparticles, method for making the same, and their biomedical applications 有权生物相容性的类似金纳米粒子，其制备方法及其生物医学应用公开(公告)号：US09162287B2
公开(公告)日：2015-10-20
申请号：US13333868
申请日：2011-12-21
申请人： Masaki Ujihara , Toyoko Imae
发明人： Masaki Ujihara , Toyoko Imae
CPC分类号： B22F9/24 , A61K41/0052 , B22F1/0018 , B22F1/0062 , B22F2001/0033 , B82Y5/00 , B82Y30/00 , C12N5/10 , C22C5/02 , Y10T428/12014
摘要： The present invention provides a method for producing gold nanoparticles using hydroxyl peroxide in an aqueous alkaline condition in the presence of a biocompatible protecting agent. The method of the invention does not involve toxic reagents and therefore are environmentally friendly. The gold nanoparticles thus produced can be used in biomedical applications including cancer therapy and drug delivery without purification.
摘要翻译： 本发明提供了在生物相容性保护剂存在下，在含水碱性条件下使用羟基过氧化物制备金纳米颗粒的方法。 本发明的方法不涉及有毒试剂，因此是环境友好的。 如此生产的金纳米颗粒可用于生物医学应用，包括癌症治疗和药物递送，无需纯化。
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8.发明授权Substrate mimicking intercellular lipids in stratum corneum and method of evaluating skin roughening using the same 有权基质在角质层中模拟细胞间脂质和使用其评估皮肤粗糙化的方法公开(公告)号：US08969088B2
公开(公告)日：2015-03-03
申请号：US12998985
申请日：2009-09-01
申请人： Takuya Saiwaki , Takashi Oka , Yuichiro Mori , Toyoko Imae , Xiaojuan Wang , Masaki Ujihara
发明人： Takuya Saiwaki , Takashi Oka , Yuichiro Mori , Toyoko Imae , Xiaojuan Wang , Masaki Ujihara
CPC分类号： G01N33/92 , G01N2800/20 , Y10T436/104165
摘要： A substrate mimicking intercellular lipids in stratum corneum consisting of a substrate and a lipid membrane formed on the substrate, wherein the lipid membrane is formed from ceramide, palmitic acid and cholesterol, and the ceramide, palmitic acid and cholesterol are present at a mass ratio of 20-70%:10-60%:20-40% (ceramide:palmitic acid:cholesterol).
摘要翻译： 在基质上形成的由底物和脂质膜构成的角质层中的模拟细胞间脂质的底物，其中脂质膜由神经酰胺，棕榈酸和胆固醇形成，神经酰胺，棕榈酸和胆固醇以质量比 20-70％：10-60％：20-40％（神经酰胺：棕榈酸：胆固醇）。
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