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公开(公告)号：US20090292241A1
公开(公告)日：2009-11-26
申请号：US12506066
申请日：2009-07-20
CPC分类号： A61F2/958 , A61M25/1002 , A61M25/1011 , A61M25/1027 , A61M25/1029 , A61M29/02 , A61M2025/0183 , A61M2025/1056 , A61M2025/107
摘要： A catheter arrangement is described that is arranged to permit a guide wire or other structure to be fed laterally from the region of an expandable working element. The catheter includes an elongate flexible tubular member and an inflatable structure carried by a distal portion of the flexible tubular member. The flexible tubular member has a guide wire lumen and at least one fluid supply lumen that is in fluid communication with the inflatable structure. The inflatable structure includes at least one, and preferably two, inflatable members (which may take the form of balloons). In the case of two inflatable members, the first and second inflatable members are radially spaced about the guide wire lumen such that at least one gap is formed between the inflatable members. With this arrangement, the distal end of a guide wire may be advanced through the guide lumen and out of a side opening such that the guide wire passes laterally between the first and second inflatable members. With such an arrangement, a guide wire passing out of the side opening in the region between the inflatable members can readily be directed into a second branch of a vessel bifurcation while the device is positioned in a first branch.
摘要翻译： 描述了布置成允许导丝或其他结构从可扩张工作元件的区域横向地供给的导管装置。 导管包括细长的柔性管状构件和由柔性管状构件的远侧部分承载的可膨胀结构。 柔性管状构件具有导丝腔和与可充气结构流体连通的至少一个流体供应腔。 可膨胀结构包括至少一个，优选两个可膨胀构件（其可以采取气球的形式）。 在两个可膨胀构件的情况下，第一和第二可膨胀构件围绕导丝管腔径向隔开，使得在可膨胀构件之间形成至少一个间隙。 通过这种布置，导丝的远端可以通过引导腔前进并且从侧开口排出，使得导丝横向地在第一和第二可膨胀构件之间通过。 通过这样的布置，在可膨胀构件之间的区域中的侧开口中的引导线可以容易地被引导到容器分叉的第二分支中，同时装置位于第一分支中。
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公开(公告)号：US20080140174A1
公开(公告)日：2008-06-12
申请号：US11506243
申请日：2006-08-17
IPC分类号： A61F2/06
CPC分类号： A61F2/958 , A61M25/1027 , A61M2025/1031
摘要： A variety of methods are described that pre-condition a balloon used in a balloon catheter in order to increase its flexibility. Generally, the membrane that forms the balloon is crumpled in order to induce a large number of irregular crumples in the balloon. The crinkling of the balloon improves its flexibility and thus the flexibility of the catheter. Most typically, torsion and/or compression are applied to the balloon membrane in order to induce the crumpling. The described crumpling can be used to increase the flexibility of a balloon of a given strength in a variety of catheters, including angioplasty catheters and stent delivery catheters. In stent delivery catheters, the resulting crinkles also have the additional benefit of improving stent retention.
摘要翻译： 描述了预先调节气球导管中使用的球囊以增加其灵活性的各种方法。 通常，形成气囊的膜被弄皱，以便在气球中引起大量的不规则褶皱。 气球的皱缩改善了其灵活性，从而提高了导管的灵活性。 最典型地，将扭转和/或压缩施加到球囊膜以引起皱巴巴。 所描述的皱巴巴可用于增加各种导管（包括血管成形术导管和支架输送导管）中给定强度的球囊的柔性。 在支架输送导管中，所产生的皱纹还具有改善支架保留的额外益处。
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公开(公告)号：US20080045896A1
公开(公告)日：2008-02-21
申请号：US11506309
申请日：2006-08-17
CPC分类号： A61F2/958 , A61F2/856 , A61F2/954 , A61F2250/0098 , A61M2025/105 , A61M2025/1072
摘要： Various improved catheter marking arrangements are described. In a first aspect of the invention, the catheter includes an expandable member (such as for example, a balloon, a stent, etc.). A pair of radiopaque end markers mark the distal and proximal ends of the expandable member. Additionally, a radiopaque intermediate marker is provided that marks an intermediate position on the expandable member. The intermediate marker may be used to mark important points on the expandable member. The markers are sized and positioned such that a surgeon utilizing the catheter in a surgical procedure would be able to readily differentiate the markers in a fluoroscopic image to determine the location of the item marked by the orientation of the catheter. In various other aspects of the invention, the intermediate marker is arranged to mark a position on the expandable member that constitutes a line of demarcation for an agent (such as a drug) carried by a balloon.
摘要翻译： 描述了各种改进的导管标记装置。 在本发明的第一方面，导管包括可扩张构件（例如气球，支架等）。 一对不透射线的端标记标记可扩张构件的远端和近端。 另外，提供标记可扩张构件上的中间位置的不透射线的中间标记。 中间标记可用于标记可扩张构件上的重要点。 标记物的大小和定位使得在外科手术中利用导管的外科医生将能够容易地在荧光透视图像中区分标记物，以确定由导管的取向标记的物品的位置。 在本发明的各种其他方面，中间标记被布置成标记可膨胀构件上构成由气球承载的试剂（例如药物）的界线的位置。
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公开(公告)号：US20080097404A1
公开(公告)日：2008-04-24
申请号：US11505697
申请日：2006-08-16
IPC分类号： A61M25/098 , A61M29/00 , A61F2/06 , A61F2/00
CPC分类号： A61M25/0108 , A61F2/856 , A61F2/954 , A61F2/958 , A61F2250/0098 , A61M2025/0008 , A61M2025/1079
摘要： Various improved catheter marking arrangements are described. In a first aspect of the invention, a first longitudinally extending radiopaque marker is positioned on the catheter. A second longitudinally extending radiopaque marker is positioned opposite the first marker at a rotational orientation that is approximately 180 degrees offset from the first marker. The second marker has a length that is sufficiently different from the first marker such that a surgeon utilizing the catheter in a surgical procedure would be able to readily differentiate the first and second markers in a fluoroscopic image based on their respective lengths in order to determine the rotational orientation of the catheter.In some embodiments, the catheter includes a lumen that has a side port that opens to a side of the catheter. The first marker is composed of a pair of axially aligned marker segments located on opposite ends of the side port. The length of the first longitudinal extending marker defined as an end-to-end length of the pair of axially aligned marker segments is longer than the length of the second marker. The markers may be formed from any suitable materials that can be clearly detected by an imaging system.
摘要翻译： 描述了各种改进的导管标记装置。 在本发明的第一方面，第一纵向延伸的不透射线的标记位于导管上。 第二纵向延伸的不透射线标记物以与第一标记物大约180度偏离的旋转方向定位成与第一标记相对。 第二标记具有与第一标记足够不同的长度，使得在外科手术中利用导管的外科医生能够根据它们各自的长度容易地区分荧光镜图像中的第一和第二标记，以便确定 导管的旋转取向。 在一些实施例中，导管包括具有向导管侧面开口的侧端口的内腔。 第一标记由位于侧端口的相对端上的一对轴向对齐的标记段组成。 被定义为一对轴向对准的标记段的端到端长度的第一纵向延伸标记的长度比第二标记的长度长。 标记可以由能够被成像系统清楚地检测到的任何合适的材料形成。
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公开(公告)号：US07578831B2
公开(公告)日：2009-08-25
申请号：US11474111
申请日：2006-06-23
IPC分类号： A61M29/00
CPC分类号： A61M25/10 , A61F2/958 , A61M25/1002 , A61M25/1011 , A61M25/1027 , A61M25/1029 , A61M25/104 , A61M2025/018 , A61M2025/0183 , A61M2025/1045 , A61M2025/1056 , A61M2025/107 , A61M2029/025
摘要： A catheter arrangement is described that is arranged to permit a guide wire or other structure to be fed laterally from the region of an expandable working element. The catheter includes an elongate flexible tubular member and an inflatable structure carried by a distal portion of the flexible tubular member. The flexible tubular member has a guide wire lumen and at least one fluid supply lumen that is in fluid communication with the inflatable structure. The inflatable structure includes at least one, and preferably two, inflatable members (which may take the form of balloons). In the case of two inflatable members, the first and second inflatable members are radially spaced about the guide wire lumen such that at least one gap is formed between the inflatable members. With this arrangement, the distal end of a guide wire may be advanced through the guide lumen and out of a side opening such that the guide wire passes laterally between the first and second inflatable members. With such an arrangement, a guide wire passing out of the side opening in the region between the inflatable members can readily be directed into a second branch of a vessel bifurcation while the device is positioned in a first branch.
摘要翻译： 描述了布置成允许导丝或其他结构从可扩张工作元件的区域横向地供给的导管装置。 导管包括细长的柔性管状构件和由柔性管状构件的远侧部分承载的可膨胀结构。 柔性管状构件具有导丝腔和与可充气结构流体连通的至少一个流体供应腔。 可膨胀结构包括至少一个，优选两个可膨胀构件（其可以采取气球的形式）。 在两个可膨胀构件的情况下，第一和第二可膨胀构件围绕导丝管腔径向隔开，使得在可膨胀构件之间形成至少一个间隙。 通过这种布置，导丝的远端可以通过引导腔前进并且从侧开口排出，使得导丝横向地在第一和第二可膨胀构件之间通过。 通过这样的布置，在可膨胀构件之间的区域中的侧开口中的引导线可以容易地被引导到容器分叉的第二分支中，同时装置位于第一分支中。
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公开(公告)号：US09060892B2
公开(公告)日：2015-06-23
申请号：US13063911
申请日：2009-09-11
申请人： Randolf Von Oepen , Lorcan James Coffey , Richard R. Newhauser , Thomas Rieth , Travis R. Yribarren
发明人： Randolf Von Oepen , Lorcan James Coffey , Richard R. Newhauser , Thomas Rieth , Travis R. Yribarren
CPC分类号： A61F2/915 , A61F2/89 , A61F2/91 , A61F2/95 , A61F2/958 , A61F2002/30019 , A61F2002/30484 , A61F2002/826 , A61F2002/828 , A61F2002/91583 , A61F2002/91591 , A61F2210/0004 , A61F2210/0014 , A61F2210/0076 , A61F2250/0071
摘要： A vascular endoprosthesis (100, 200, 300, 400, 500, 600) includes a radially-expandable first segment and a radially expandable second segment. The vascular endoprosthesis further includes first and second coupling elements. The first coupling element extends from the proximal end of the first segment toward the distal end of the second segment, and the second coupling element extends from the distal end of the second segment toward the proximal end of the first segment. The first and second coupling elements cooperate one with another to couple the first and second segments together when the vascular endoprosthesis is in a delivery configuration and to decouple the first and second segments when the vascular endoprosthesis is in a deployed configuration.
摘要翻译： 血管内假体（100,200,300,400,500,600）包括径向可扩张的第一段和可径向扩张的第二段。 血管内假体进一步包括第一和第二联接元件。 第一联接元件从第一段的近端延伸到第二段的远端，并且第二联接元件从第二段的远端朝向第一段的近端延伸。 当血管内用假体处于输送构型中时，第一和第二联接元件彼此配合以将第一和第二段联接在一起，并且当血管内用假体处于展开构型时将第一和第二段分离。
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公开(公告)号：US20110224777A1
公开(公告)日：2011-09-15
申请号：US13063911
申请日：2009-09-11
申请人： Randolf Von Oepen , Lorcan James Coffey , Richard R. Newhauser , Thomas Rieth , Travis R. Yribarren
发明人： Randolf Von Oepen , Lorcan James Coffey , Richard R. Newhauser , Thomas Rieth , Travis R. Yribarren
IPC分类号： A61F2/82
CPC分类号： A61F2/915 , A61F2/89 , A61F2/91 , A61F2/95 , A61F2/958 , A61F2002/30019 , A61F2002/30484 , A61F2002/826 , A61F2002/828 , A61F2002/91583 , A61F2002/91591 , A61F2210/0004 , A61F2210/0014 , A61F2210/0076 , A61F2250/0071
摘要： A vascular endoprosthesis (100, 200, 300, 400, 500, 600) includes a radially-expandable first segment and a radially expandable second segment. The vascular endoprosthesis further includes first and second coupling elements. The first coupling element extends from the proximal end of the first segment toward the distal end of the second segment, and the second coupling element extends from the distal end of the second segment toward the proximal end of the first segment. The first and second coupling elements cooperate one with another to couple the first and second segments together when the vascular endoprosthesis is in a delivery configuration and to decouple the first and second segments when the vascular endoprosthesis is in a deployed configuration.
摘要翻译： 血管内假体（100,200,300,400,500,600）包括径向可扩张的第一段和可径向扩张的第二段。 血管内假体进一步包括第一和第二联接元件。 第一联接元件从第一段的近端延伸到第二段的远端，并且第二联接元件从第二段的远端朝向第一段的近端延伸。 当血管内用假体处于输送构型中时，第一和第二联接元件彼此配合以将第一和第二段联接在一起，并且当血管内用假体处于展开构型时将第一和第二段分离。
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8.发明授权Agent delivery catheter having a radially expandable centering support member 有权药剂递送导管具有径向可扩张的居中支撑构件公开(公告)号：US08568355B2
公开(公告)日：2013-10-29
申请号：US13323122
申请日：2011-12-12
申请人： Sung Woo Min , Randolf von Oepen , Binh T. Nguyen , Kevin J. Ehrenreich , William E. Webler, Jr. , Rommel Lumauig , Gregory W. Chan , Lorcan J. Coffey , Travis R. Yribarren , Jesus Magana
发明人： Sung Woo Min , Randolf von Oepen , Binh T. Nguyen , Kevin J. Ehrenreich , William E. Webler, Jr. , Rommel Lumauig , Gregory W. Chan , Lorcan J. Coffey , Travis R. Yribarren , Jesus Magana
CPC分类号： A61M25/0155 , A61M25/0013 , A61M25/0068 , A61M25/008 , A61M25/0082 , A61M25/0084 , A61M25/04 , A61M25/0606 , A61M25/1002 , A61M25/1011 , A61M2025/0081 , A61M2025/0092 , A61M2025/0096 , A61M2025/0681 , A61M2025/1047
摘要： A catheter for delivering an agent to an injection site in a wall of a patient's body lumen, with an elongated shaft having a needle-through lumen slidably containing a needle therein, and an expandable member on the distal shaft section which has a collapsed configuration and a radially expanded configuration. In the radially expanded configuration, the expandable member supports the shaft in a position spaced away from the body lumen wall, and the needle slidably exits the needle-through lumen in the extended configuration through the port spaced away from the body lumen wall as a portion of the expandable member maintains the position of the port section of the shaft in the body lumen. The expandable member typically has an open-walled, helical, or lobed configuration providing a perfusion path along the expandable member.
摘要翻译： 一种导管，用于将药剂递送到患者体腔的壁中的注射部位，细长轴具有可滑动地包含针的针穿腔，以及具有折叠构型的远侧轴部上的可扩张构件，以及 径向扩张构型。 在径向展开的构造中，可扩张构件将轴支撑在远离体腔壁的位置上，并且针以延伸构型通过与体腔内壁间隔的端口可滑动地离开针穿腔，作为一部分 所述可扩张构件保持所述轴的所述端口部分在所述体腔中的位置。 可膨胀构件通常具有提供沿着可膨胀构件的灌注路径的开放壁，螺旋形或叶状结构。
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公开(公告)号：US20120046729A1
公开(公告)日：2012-02-23
申请号：US13087341
申请日：2011-04-14
IPC分类号： A61F2/82
CPC分类号： A61F2/915 , A61F2/2475 , A61F2/88 , A61F2/958 , A61F2002/825 , A61F2002/8483 , A61F2002/91558 , A61F2002/91566 , A61F2220/005 , A61F2220/0058 , A61F2220/0075 , A61F2230/0054 , A61F2230/0076 , A61F2230/0078
摘要： Devices and methods for treating veins and venous conditions, such as chronic cerebrospinal venous insufficiency, are provided. In one aspect, the disclosed subject matter provides an intraluminal scaffold having a generally tubular body with a lumen defined therethrough, the tubular body having a compressed condition for delivery and an expanded condition for implant within a vessel having a distended portion, at least a length of the tubular body configured to form an enlarged portion in the expanded condition to engage a wall of the distended portion of the vessel. Methods for fabricating and using the scaffold, methods for remodeling a vein, and methods of deploying a medical device in a vessel without negatively impacting the function of a valve of the vessel, are also provided.
摘要翻译： 提供了用于治疗静脉和静脉疾病如慢性脑脊髓静脉功能不全的装置和方法。 在一个方面，所公开的主题提供了一种管腔内支架，其具有通过其限定的内腔的大体管状体，该管状体具有用于输送的压缩状态和用于植入物的膨胀状态，该容器具有扩张部分，至少长度 所述管体被构造成在膨胀状态下形成扩大部分以接合容器的扩张部分的壁。 还提供了制造和使用支架的方法，用于重建静脉的方法，以及在容器中部署医疗装置的方法，而不会不利地影响容器的阀的功能。
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公开(公告)号：US20110213451A1
公开(公告)日：2011-09-01
申请号：US13037008
申请日：2011-02-28
CPC分类号： A61F2/0095 , A61F2002/9505 , A61F2002/9583 , A61F2002/9665
摘要： Device shields for packaging and protecting medical devices during storage and deployment. A device shield includes a housing configured to maintain a medical device and at least a portion of a medical device delivery apparatus within the housing, and a limit element having a first constraining position and a second open position.
摘要翻译： 在存储和部署期间用于包装和保护医疗设备的设备屏蔽。 设备屏蔽包括被配置为将医疗设备和医疗设备传送设备的至少一部分保持在壳体内的壳体，以及具有第一约束位置和第二打开位置的限制元件。
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