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公开(公告)号:US08613914B2
公开(公告)日:2013-12-24
申请号:US13614902
申请日:2012-09-13
IPC分类号: A61K45/00
CPC分类号: C07K7/06 , A61K31/403 , A61K31/4439 , A61K38/06 , A61K38/07 , A61K38/08 , A61K45/06 , C07D209/96 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/14 , C07D417/14 , C07K5/06165 , C07K5/08 , C07K5/0808 , C07K5/0812 , C07K5/10 , C07K5/101 , C07K5/1016
摘要: The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases.
摘要翻译: 本申请描述了可用于治疗,预防和/或改善人类疾病的有机化合物。
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2.Derivatised proline containing peptide compounds as protease inhibitors 有权
标题翻译: 含有肽化合物的衍生脯氨酸作为蛋白酶抑制剂公开(公告)号:US08512690B2
公开(公告)日:2013-08-20
申请号:US12755852
申请日:2010-04-07
IPC分类号: A61K45/00
CPC分类号: C07K7/06 , A61K31/403 , A61K31/4439 , A61K38/06 , A61K38/07 , A61K38/08 , A61K45/06 , C07D209/96 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/14 , C07D417/14 , C07K5/06165 , C07K5/08 , C07K5/0808 , C07K5/0812 , C07K5/10 , C07K5/101 , C07K5/1016
摘要: The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases.
摘要翻译: 本申请描述了可用于治疗,预防和/或改善人类疾病的有机化合物。
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公开(公告)号:US08445527B2
公开(公告)日:2013-05-21
申请号:US13477866
申请日:2012-05-22
申请人: Michael Patane , Prakash Raman , David Thomas Parker , Jiping Fu , Branko Radetich , Mohindra Seepersaud , Aregahegn Yifru , Rui Zheng , Trixi Brandl , Francois Lenoir , Pascal Rigollier , Oliver Simic
发明人: Michael Patane , Prakash Raman , David Thomas Parker , Jiping Fu , Branko Radetich , Mohindra Seepersaud , Aregahegn Yifru , Rui Zheng , Trixi Brandl , Francois Lenoir , Pascal Rigollier , Oliver Simic
IPC分类号: A61K31/5377 , A61K31/506 , A61K31/497 , A61K31/4439 , A61K31/454 , A61K31/427 , A61K31/422 , A61K31/4178 , A61K31/4155 , A61K31/403
CPC分类号: A61K38/07 , A61K38/00 , A61K38/06 , A61K45/06 , C07D209/96 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D487/10 , C07D491/20 , C07D495/10 , C07D498/04 , C07D498/10 , C07K5/06034 , C07K5/06078 , C07K5/06165 , C07K5/0808 , C07K5/0812 , C07K5/101 , C07K5/1016
摘要: The present invention provides a method of treating a HCV infection in a subject in need thereof by administering a compound of Formula I: or pharmaceutically acceptable salts thereof or stereoisomers thereof.
摘要翻译: 本发明提供了通过给予式I化合物或其药学上可接受的盐或其立体异构体来治疗有需要的受试者的HCV感染的方法。
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公开(公告)号:US20140357551A1
公开(公告)日:2014-12-04
申请号:US14462406
申请日:2014-08-18
CPC分类号: C07K7/06 , A61K31/403 , A61K31/4439 , A61K38/06 , A61K38/07 , A61K38/08 , A61K45/06 , C07D209/96 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/14 , C07D417/14 , C07K5/06165 , C07K5/08 , C07K5/0808 , C07K5/0812 , C07K5/10 , C07K5/101 , C07K5/1016
摘要: The present application describes organic compounds of Formula (II) that are useful for the treatment, prevention and/or amelioration of human diseases.
摘要翻译: 本申请描述了可用于治疗,预防和/或改善人类疾病的式(II)的有机化合物。
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公开(公告)号:US08840878B2
公开(公告)日:2014-09-23
申请号:US13614813
申请日:2012-09-13
IPC分类号: A61K45/00 , C07D417/14 , C07D401/12 , C07D209/96 , C07D401/14 , C07K5/087 , C07K5/078 , C07K5/107 , C07D403/12 , C07D403/14 , C07D405/14 , C07K5/103 , C07K5/083
CPC分类号: C07K7/06 , A61K31/403 , A61K31/4439 , A61K38/06 , A61K38/07 , A61K38/08 , A61K45/06 , C07D209/96 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/14 , C07D417/14 , C07K5/06165 , C07K5/08 , C07K5/0808 , C07K5/0812 , C07K5/10 , C07K5/101 , C07K5/1016
摘要: The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases.
摘要翻译: 本申请描述了可用于治疗,预防和/或改善人类疾病的有机化合物。
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公开(公告)号:US08211932B2
公开(公告)日:2012-07-03
申请号:US12879644
申请日:2010-09-10
申请人: Michael Patane , Prakash Raman , David Thomas Parker , Jiping Fu , Branko Radetich , Mohindra Seepersaud , Aregahegn Yifru , Rui Zheng , Trixi Brandl , Francois Lenoir , Pascal Rigollier , Oliver Simic
发明人: Michael Patane , Prakash Raman , David Thomas Parker , Jiping Fu , Branko Radetich , Mohindra Seepersaud , Aregahegn Yifru , Rui Zheng , Trixi Brandl , Francois Lenoir , Pascal Rigollier , Oliver Simic
IPC分类号: C07D417/12 , C07D403/12 , C07D401/12 , C07D409/12 , C07D417/14 , C07D405/12 , C07D413/12 , C07D405/04 , C07D403/04 , C07D413/14 , C07D409/14 , C07D405/14 , C07D207/00 , C07D209/96 , A61K31/5377 , A61K31/506 , A61K31/497 , A61K31/4439 , A61K31/454 , A61K31/427 , A61K31/422 , A61K31/4178 , A61K31/4155 , A61K31/403
CPC分类号: A61K38/07 , A61K38/00 , A61K38/06 , A61K45/06 , C07D209/96 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D487/10 , C07D491/20 , C07D495/10 , C07D498/04 , C07D498/10 , C07K5/06034 , C07K5/06078 , C07K5/06165 , C07K5/0808 , C07K5/0812 , C07K5/101 , C07K5/1016
摘要: The present application describes organic compounds of the Formula I that are useful for the treatment, prevention and/or amelioration of human diseases.
摘要翻译: 本申请描述了可用于治疗,预防和/或改善人类疾病的式I的有机化合物。
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公开(公告)号:US20110182850A1
公开(公告)日:2011-07-28
申请号:US12755856
申请日:2010-04-07
IPC分类号: A61K38/20 , C07D209/96 , C07D401/14 , C07D401/12 , C07D471/04 , C07D403/14 , C07D403/12 , C07D413/12 , A61K38/21 , A61K31/713 , A61K31/7036 , A61K31/437 , A61K31/7056 , A61K31/496 , A61K31/427 , A61K38/13 , A61K31/7048 , A61K31/403 , A61K31/454 , A61K31/4375 , A61K31/4184 , A61K31/497 , A61K31/5377 , A61P31/14
CPC分类号: C07D401/12 , A61K38/13 , A61K38/2013 , A61K38/204 , A61K38/208 , A61K38/21 , A61K38/212 , C07D403/12 , C07D413/12 , C07K5/101 , C07K7/06 , A61K2300/00
摘要: The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases.
摘要翻译: 本申请描述了可用于治疗,预防和/或改善人类疾病的有机化合物。
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公开(公告)号:US20100331243A1
公开(公告)日:2010-12-30
申请号:US12879644
申请日:2010-09-10
申请人: Trixi Brandl , Jiping Fu , Francois Lenoir , David Thomas Parker , Michael Patane , Branko Radetich , Prakash Raman , Pascal Rigollier , Mohindra Seepersaud , Oliver Simic , Aregahegn Yifru , Rui Zheng
发明人: Trixi Brandl , Jiping Fu , Francois Lenoir , David Thomas Parker , Michael Patane , Branko Radetich , Prakash Raman , Pascal Rigollier , Mohindra Seepersaud , Oliver Simic , Aregahegn Yifru , Rui Zheng
CPC分类号: A61K38/07 , A61K38/00 , A61K38/06 , A61K45/06 , C07D209/96 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D487/10 , C07D491/20 , C07D495/10 , C07D498/04 , C07D498/10 , C07K5/06034 , C07K5/06078 , C07K5/06165 , C07K5/0808 , C07K5/0812 , C07K5/101 , C07K5/1016
摘要: The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases.
摘要翻译: 本申请描述了可用于治疗,预防和/或改善人类疾病的有机化合物。
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公开(公告)号:US20100260709A1
公开(公告)日:2010-10-14
申请号:US12755852
申请日:2010-04-07
IPC分类号: A61K38/20 , C07D209/54 , C07D211/18 , C07D273/01 , A61K31/4025 , A61K31/4439 , A61K31/497 , A61K31/5377 , A61K38/21 , A61K31/713 , A61K31/437 , A61K31/7056 , A61K31/7036 , A61K31/7076 , A61K31/496 , A61K38/13 , A61K31/7105 , A61P31/20
CPC分类号: C07K7/06 , A61K31/403 , A61K31/4439 , A61K38/06 , A61K38/07 , A61K38/08 , A61K45/06 , C07D209/96 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/14 , C07D417/14 , C07K5/06165 , C07K5/08 , C07K5/0808 , C07K5/0812 , C07K5/10 , C07K5/101 , C07K5/1016
摘要: The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases.
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公开(公告)号:US20070286842A1
公开(公告)日:2007-12-13
申请号:US11697894
申请日:2007-04-09
申请人: Trixi Brandl , Jiping Fu , Francois Lenoir , David Parker , Michael Patane , Branko Redetich , Prakash Raman , Pascal Rigollier , Mohindra Seepersaud , Oliver Simic , Aregahegn Yifru , Rui Zheng
发明人: Trixi Brandl , Jiping Fu , Francois Lenoir , David Parker , Michael Patane , Branko Redetich , Prakash Raman , Pascal Rigollier , Mohindra Seepersaud , Oliver Simic , Aregahegn Yifru , Rui Zheng
IPC分类号: A61K38/21 , A61K31/40 , A61K31/421 , A61K31/44 , A61P31/12 , C07D207/00 , C07D239/02 , C07D251/02 , C07D295/00 , C12N9/99 , C12N7/06 , C07D263/52 , C07D241/02 , C07D213/02 , A61P7/00 , A61K31/495 , A61K31/53 , A61K31/5377
CPC分类号: A61K38/07 , A61K38/00 , A61K38/06 , A61K45/06 , C07D209/96 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D487/10 , C07D491/20 , C07D495/10 , C07D498/04 , C07D498/10 , C07K5/06034 , C07K5/06078 , C07K5/06165 , C07K5/0808 , C07K5/0812 , C07K5/101 , C07K5/1016
摘要: The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases.
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