-
公开(公告)号：US08445527B2
公开(公告)日：2013-05-21
申请号：US13477866
申请日：2012-05-22
申请人： Michael Patane , Prakash Raman , David Thomas Parker , Jiping Fu , Branko Radetich , Mohindra Seepersaud , Aregahegn Yifru , Rui Zheng , Trixi Brandl , Francois Lenoir , Pascal Rigollier , Oliver Simic
发明人： Michael Patane , Prakash Raman , David Thomas Parker , Jiping Fu , Branko Radetich , Mohindra Seepersaud , Aregahegn Yifru , Rui Zheng , Trixi Brandl , Francois Lenoir , Pascal Rigollier , Oliver Simic
IPC分类号： A61K31/5377 , A61K31/506 , A61K31/497 , A61K31/4439 , A61K31/454 , A61K31/427 , A61K31/422 , A61K31/4178 , A61K31/4155 , A61K31/403
CPC分类号： A61K38/07 , A61K38/00 , A61K38/06 , A61K45/06 , C07D209/96 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D487/10 , C07D491/20 , C07D495/10 , C07D498/04 , C07D498/10 , C07K5/06034 , C07K5/06078 , C07K5/06165 , C07K5/0808 , C07K5/0812 , C07K5/101 , C07K5/1016
摘要： The present invention provides a method of treating a HCV infection in a subject in need thereof by administering a compound of Formula I: or pharmaceutically acceptable salts thereof or stereoisomers thereof.
摘要翻译： 本发明提供了通过给予式I化合物或其药学上可接受的盐或其立体异构体来治疗有需要的受试者的HCV感染的方法。
-
公开(公告)号：US20120231998A1
公开(公告)日：2012-09-13
申请号：US13477866
申请日：2012-05-22
申请人： Trixi Brandl , Jiping Fu , Francois Lenoir , David Thomas Parker , Michael Patane , Branko Radetich , Prakash Raman , Pascal Rigollier , Mohindra Seepersaud , Oliver Simic , Aregahegn Yifru , Rui Zheng
发明人： Trixi Brandl , Jiping Fu , Francois Lenoir , David Thomas Parker , Michael Patane , Branko Radetich , Prakash Raman , Pascal Rigollier , Mohindra Seepersaud , Oliver Simic , Aregahegn Yifru , Rui Zheng
CPC分类号： A61K38/07 , A61K38/00 , A61K38/06 , A61K45/06 , C07D209/96 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D487/10 , C07D491/20 , C07D495/10 , C07D498/04 , C07D498/10 , C07K5/06034 , C07K5/06078 , C07K5/06165 , C07K5/0808 , C07K5/0812 , C07K5/101 , C07K5/1016
摘要： The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases.
摘要翻译： 本申请描述了可用于治疗，预防和/或改善人类疾病的有机化合物。
-
公开(公告)号：US07825152B2
公开(公告)日：2010-11-02
申请号：US11697894
申请日：2007-04-09
申请人： Trixi Brandl , Jiping Fu , Francois Lenoir , David Thomas Parker , Michael Patane , Branko Radetich , Prakash Raman , Pascal Rigollier , Mohindra Seepersaud , Oliver Simic , Aregahegn Yifru , Rui Zheng
发明人： Trixi Brandl , Jiping Fu , Francois Lenoir , David Thomas Parker , Michael Patane , Branko Radetich , Prakash Raman , Pascal Rigollier , Mohindra Seepersaud , Oliver Simic , Aregahegn Yifru , Rui Zheng
IPC分类号： C07D417/12 , C07D403/12 , C07D401/12 , C07D409/12 , C07D417/14 , C07D405/12 , C07D413/12 , C07D405/04 , C07D403/04 , C07D413/14 , C07D409/14 , C07D405/14 , C07D207/00 , C07D209/96 , A61K31/5377 , A61K31/506 , A61K31/497 , A61K31/4439 , A61K31/454 , A61K31/427 , A61K31/422 , A61K31/4178 , A61K31/4155 , A61K31/403
CPC分类号： A61K38/07 , A61K38/00 , A61K38/06 , A61K45/06 , C07D209/96 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D487/10 , C07D491/20 , C07D495/10 , C07D498/04 , C07D498/10 , C07K5/06034 , C07K5/06078 , C07K5/06165 , C07K5/0808 , C07K5/0812 , C07K5/101 , C07K5/1016
摘要： The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases.
摘要翻译： 本申请描述了可用于治疗，预防和/或改善人类疾病的有机化合物。
-
公开(公告)号：US08211932B2
公开(公告)日：2012-07-03
申请号：US12879644
申请日：2010-09-10
申请人： Michael Patane , Prakash Raman , David Thomas Parker , Jiping Fu , Branko Radetich , Mohindra Seepersaud , Aregahegn Yifru , Rui Zheng , Trixi Brandl , Francois Lenoir , Pascal Rigollier , Oliver Simic
发明人： Michael Patane , Prakash Raman , David Thomas Parker , Jiping Fu , Branko Radetich , Mohindra Seepersaud , Aregahegn Yifru , Rui Zheng , Trixi Brandl , Francois Lenoir , Pascal Rigollier , Oliver Simic
IPC分类号： C07D417/12 , C07D403/12 , C07D401/12 , C07D409/12 , C07D417/14 , C07D405/12 , C07D413/12 , C07D405/04 , C07D403/04 , C07D413/14 , C07D409/14 , C07D405/14 , C07D207/00 , C07D209/96 , A61K31/5377 , A61K31/506 , A61K31/497 , A61K31/4439 , A61K31/454 , A61K31/427 , A61K31/422 , A61K31/4178 , A61K31/4155 , A61K31/403
CPC分类号： A61K38/07 , A61K38/00 , A61K38/06 , A61K45/06 , C07D209/96 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D487/10 , C07D491/20 , C07D495/10 , C07D498/04 , C07D498/10 , C07K5/06034 , C07K5/06078 , C07K5/06165 , C07K5/0808 , C07K5/0812 , C07K5/101 , C07K5/1016
摘要： The present application describes organic compounds of the Formula I that are useful for the treatment, prevention and/or amelioration of human diseases.
摘要翻译： 本申请描述了可用于治疗，预防和/或改善人类疾病的式I的有机化合物。
-
公开(公告)号：US20100331243A1
公开(公告)日：2010-12-30
申请号：US12879644
申请日：2010-09-10
申请人： Trixi Brandl , Jiping Fu , Francois Lenoir , David Thomas Parker , Michael Patane , Branko Radetich , Prakash Raman , Pascal Rigollier , Mohindra Seepersaud , Oliver Simic , Aregahegn Yifru , Rui Zheng
发明人： Trixi Brandl , Jiping Fu , Francois Lenoir , David Thomas Parker , Michael Patane , Branko Radetich , Prakash Raman , Pascal Rigollier , Mohindra Seepersaud , Oliver Simic , Aregahegn Yifru , Rui Zheng
CPC分类号： A61K38/07 , A61K38/00 , A61K38/06 , A61K45/06 , C07D209/96 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D487/10 , C07D491/20 , C07D495/10 , C07D498/04 , C07D498/10 , C07K5/06034 , C07K5/06078 , C07K5/06165 , C07K5/0808 , C07K5/0812 , C07K5/101 , C07K5/1016
摘要： The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases.
摘要翻译： 本申请描述了可用于治疗，预防和/或改善人类疾病的有机化合物。
-
公开(公告)号：US20070286842A1
公开(公告)日：2007-12-13
申请号：US11697894
申请日：2007-04-09
申请人： Trixi Brandl , Jiping Fu , Francois Lenoir , David Parker , Michael Patane , Branko Redetich , Prakash Raman , Pascal Rigollier , Mohindra Seepersaud , Oliver Simic , Aregahegn Yifru , Rui Zheng
发明人： Trixi Brandl , Jiping Fu , Francois Lenoir , David Parker , Michael Patane , Branko Redetich , Prakash Raman , Pascal Rigollier , Mohindra Seepersaud , Oliver Simic , Aregahegn Yifru , Rui Zheng
IPC分类号： A61K38/21 , A61K31/40 , A61K31/421 , A61K31/44 , A61P31/12 , C07D207/00 , C07D239/02 , C07D251/02 , C07D295/00 , C12N9/99 , C12N7/06 , C07D263/52 , C07D241/02 , C07D213/02 , A61P7/00 , A61K31/495 , A61K31/53 , A61K31/5377
CPC分类号： A61K38/07 , A61K38/00 , A61K38/06 , A61K45/06 , C07D209/96 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D487/10 , C07D491/20 , C07D495/10 , C07D498/04 , C07D498/10 , C07K5/06034 , C07K5/06078 , C07K5/06165 , C07K5/0808 , C07K5/0812 , C07K5/101 , C07K5/1016
摘要： The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases.
-
公开(公告)号：US20080045530A1
公开(公告)日：2008-02-21
申请号：US11697889
申请日：2007-04-09
申请人： Trixi Brandl , Shawn Britt , Sylvain Cottens , Claus Ehrhardt , Jiping Fu , Subramanian Karur , Hongju Li , Peichao Lu , David Parker , Michael Patane , Branko Radetich , Prakash Raman , Stefan Randl , Pascal Rigollier , Mohindra Seepersaud , Oliver Simic , Ritesh Tichkule , Yanyi Zhu
发明人： Trixi Brandl , Shawn Britt , Sylvain Cottens , Claus Ehrhardt , Jiping Fu , Subramanian Karur , Hongju Li , Peichao Lu , David Parker , Michael Patane , Branko Radetich , Prakash Raman , Stefan Randl , Pascal Rigollier , Mohindra Seepersaud , Oliver Simic , Ritesh Tichkule , Yanyi Zhu
IPC分类号： A61K31/195 , A61K31/40 , A61K31/421 , A61K31/445 , A61K31/47 , A61K31/4965 , A61K31/497 , A61K31/5375 , A61P31/12 , C07D207/00 , C07D217/00 , C07D241/02
CPC分类号： C07D403/12 , C07D207/08 , C07D217/04 , C07D241/04 , C07D401/14 , C07D405/14 , C07D407/12 , C07D413/04 , C07D413/12 , C07D413/14
摘要： The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases.
摘要翻译： 本申请描述了可用于治疗，预防和/或改善人类疾病的有机化合物。
-
公开(公告)号：US20070265281A1
公开(公告)日：2007-11-15
申请号：US11697901
申请日：2007-04-09
申请人： Sylvain Cottens , Claus Ehrhardt , Jiping Fu , David Parker , Michael Patane , Branko Radetich , Prakash Raman , Stefan Randl , Pascal Rigollier , Mohindra Seepersaud , Oliver Simic , Dongpeng Wan
发明人： Sylvain Cottens , Claus Ehrhardt , Jiping Fu , David Parker , Michael Patane , Branko Radetich , Prakash Raman , Stefan Randl , Pascal Rigollier , Mohindra Seepersaud , Oliver Simic , Dongpeng Wan
IPC分类号： A61K31/4965 , A61K31/16 , A61K31/18 , C07C233/00 , C07D209/04 , C07D241/02 , C07C303/00 , A61P31/00 , A61K31/405
CPC分类号： C07K5/0812 , A61K38/00 , C07K5/06078 , C07K5/06165 , C07K5/0808 , C07K5/1016
摘要： The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases.
摘要翻译： 本申请描述了可用于治疗，预防和/或改善人类疾病的有机化合物。
-
公开(公告)号：US07790719B2
公开(公告)日：2010-09-07
申请号：US11878708
申请日：2007-07-26
IPC分类号： A61K31/505 , A61K31/535 , A61K31/517 , A61K31/445 , C07D239/02 , C07D233/88 , C07D413/14 , C07D239/70
CPC分类号： C07C279/22 , C07C317/32 , C07C2601/02 , C07C2601/08 , C07C2601/14 , C07C2602/10 , C07D207/12 , C07D207/14 , C07D207/16 , C07D207/22 , C07D209/14 , C07D211/26 , C07D211/34 , C07D211/60 , C07D211/62 , C07D213/40 , C07D217/02 , C07D231/12 , C07D233/56 , C07D233/88 , C07D239/16 , C07D239/42 , C07D249/08 , C07D295/13 , C07D295/185 , C07D307/79 , C07D333/20 , C07D333/38 , C07D401/06 , C07D407/12 , C07D409/12 , C07D451/04 , C07D453/02 , C07D471/10
摘要： This invention provides compounds and methods for treating melanocortin receptor associated disorders, such as weight loss disorders including cachexia resulting from cancer and other chronic illnesses. The compounds are represented by formula I: wherein X is oxygen or sulfur; G is G1 or G2: L1, L2, L3 and Q are linker groups, and Rings A, B and C, and R1-R14 are described in the specification. The compounds are antagonists of melanocortin receptors.
摘要翻译： 本发明提供了用于治疗黑皮质素受体相关疾病的化合物和方法，例如包括由癌症和其它慢性疾病引起的恶病质的体重减轻障碍。 化合物由式I表示：其中X是氧或硫; G是G1或G2：L1，L2，L3和Q是连接基团，环A，B和C以及R 1 -R 14在本说明书中描述。 这些化合物是黑皮质素受体的拮抗剂。
-
公开(公告)号：US20100144009A1
公开(公告)日：2010-06-10
申请号：US12520745
申请日：2007-12-20
申请人： Michael Patane , Akshat Talwalkar
发明人： Michael Patane , Akshat Talwalkar
IPC分类号： C12N9/02
CPC分类号： C12N9/0069 , A01H5/10 , C07K1/00 , C07K1/14
摘要： The present invention relates to the extraction and purification of lipoxygenase from plant matter, including soy beans. A process for purifying lipoxygenase from plant matter is provided.
摘要翻译： 本发明涉及从植物物质（包括大豆）中提取和纯化脂氧合酶。 提供了从植物物质中纯化脂氧合酶的方法。
-
-
-
-
-
-
-
-
-
搜索结果
33 条记录 (耗时 0.054 秒)
