公开(公告)号：US20180037646A1

公开(公告)日：2018-02-08

申请号：US15698082

申请日：2017-09-07

Applicant: UCB BIOPHARMA SPRL

Inventor： Thomas Allen Ceska ,  Alistair James Henry ,  Jiye Shi

IPC: C07K16/24 ,  C07K14/54

CPC classification number: C07K16/244 ,  C07K14/54 ,  C07K2299/00 ,  C07K2317/24 ,  C07K2317/31 ,  C07K2317/34 ,  C07K2317/54 ,  C07K2317/55 ,  C07K2317/76 ,  C07K2317/92

Abstract: The present invention relates neutralising epitopes of IL-17A and IL-17F and antibodies which bind those epitopes. The present invention also relates to the therapeutic uses of the antibody molecules and methods for producing them.

公开(公告)号：US11220547B2

公开(公告)日：2022-01-11

申请号：US16299407

申请日：2019-03-12

Applicant: UCB BIOPHARMA SPRL

Inventor： Paul Alan Atherfold ,  Thomas Allen Ceska ,  Helene Margaret Finney ,  Lara Kevorkian ,  Kaushik Sarkar ,  Bryan John Smith ,  Kerry Louise Tyson

IPC: C07H21/02 ,  C07H21/04 ,  C12P21/06 ,  C12P21/04 ,  C12N5/00 ,  C12N5/16 ,  C12N1/20 ,  C07K16/28 ,  A61K47/60 ,  A61K47/68 ,  C07K16/00 ,  A61K39/00

Abstract: The disclosure relates to antibodies specific to FcRn, formulations comprising the same, use of each in therapy, processes for expressing and optionally formulating said antibody, DNA encoding the antibodies and hosts comprising said DNA.

公开(公告)号：US10273302B2

公开(公告)日：2019-04-30

申请号：US15036209

申请日：2014-11-12

Applicant: UCB BIOPHARMA SPRL

Inventor： Paul Alan Atherfold ,  Thomas Allen Ceska ,  Helene Margaret Finney ,  Lara Kevorkian ,  Kaushik Sarkar ,  Bryan John Smith ,  Kerry Louise Tyson

IPC: C07K16/00 ,  C12P21/08 ,  A61K39/395 ,  A61K39/40 ,  C07K16/28 ,  A61K47/60 ,  A61K47/68 ,  A61K39/00

Abstract: The disclosure relates to antibodies specific to FcRn, formulations comprising the same, use of each in therapy, processes for expressing and optionally formulating said antibody, DNA encoding the antibodies and hosts comprising said DNA.

公开(公告)号：US09771420B2

公开(公告)日：2017-09-26

申请号：US14695677

申请日：2015-06-29

Applicant: UCB BIOPHARMA SPRL

Inventor： Thomas Allen Ceska ,  Alistar James Henry ,  Jiye Shi

IPC: A61K39/395 ,  C07K16/24 ,  C07K14/54

CPC classification number: C07K16/244 ,  C07K14/54 ,  C07K2299/00 ,  C07K2317/24 ,  C07K2317/31 ,  C07K2317/34 ,  C07K2317/54 ,  C07K2317/55 ,  C07K2317/76 ,  C07K2317/92

Abstract: The present invention relates neutralizing epitopes of IL-17A and IL-17F and antibodies which bind those epitopes. The present invention also relates to the therapeutic uses of the antibody molecules and methods for producing them.