公开(公告)号：US20150118240A1

公开(公告)日：2015-04-30

申请号：US14400812

申请日：2013-05-13

Applicant: UCB Biopharma SPRL

Inventor： Helene Margaret Finney ,  Alastair David Griffiths Lawson ,  Stevan Graham Shaw ,  Bryan John Smith ,  Kerry Louise Tyson ,  Lara Kevorkian ,  Christoph Meier ,  Kaushik Sarkar ,  Paul Alan Atherfold

IPC: C07K16/28 ,  G01N33/50 ,  G01N33/68 ,  A61K47/48 ,  A61K39/395

CPC classification number: C07K16/283 ,  A61K39/3955 ,  A61K47/60 ,  A61K47/643 ,  A61K2039/505 ,  C07K2317/21 ,  C07K2317/24 ,  C07K2317/33 ,  C07K2317/55 ,  C07K2317/565 ,  C07K2317/76 ,  C07K2317/92 ,  G01N33/5047 ,  G01N33/564 ,  G01N33/6854 ,  G01N33/6857 ,  G01N33/6893 ,  G01N2333/70535 ,  G01N2500/02 ,  G01N2500/10 ,  G01N2800/104 ,  G01N2800/24 ,  G01N2800/28

Abstract: The disclosure relates to antibodies specific to FcRn, formulations comprising the same, use of each in therapy, processes for expressing and optionally formulating said antibody, DNA encoding the antibodies and hosts comprising said DNA.

Abstract translation: 本公开涉及对FcRn特异性的抗体，包含其的制剂，治疗中的每一种的使用，用于表达和任选配制所述抗体的方法，编码抗体的DNA和包含所述DNA的宿主。

公开(公告)号：US09957320B2

公开(公告)日：2018-05-01

申请号：US15180916

申请日：2016-06-13

Applicant: UCB BIOPHARMA SPRL

Inventor： Neil Gozzard ,  Alastair David Griffiths Lawson ,  Daniel John Lightwood ,  Roger Thomas Palframan ,  Bryan John Smith ,  Kerry Louise Tyson

IPC: C07K16/24 ,  A61K39/395 ,  A61K9/00 ,  A61K39/00

CPC classification number: C07K16/244 ,  A61K9/0078 ,  A61K39/395 ,  A61K39/3955 ,  A61K2039/505 ,  A61K2039/544 ,  C07K2317/24 ,  C07K2317/33 ,  C07K2317/51 ,  C07K2317/515 ,  C07K2317/55 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/76 ,  C07K2317/92 ,  C07K2317/94

Abstract: The invention relates to antibody molecules having specificity for antigenic determinants of human IL-13, therapeutic uses of the antibody molecules and methods for producing antibody molecules.

公开(公告)号：US20160289323A1

公开(公告)日：2016-10-06

申请号：US15180916

申请日：2016-06-13

Applicant: UCB BIOPHARMA SPRL

Inventor： Neil Gozzard ,  Alastair David Griffiths Lawson ,  Daniel John Lightwood ,  Roger Thomas Palframan ,  Bryan John Smith ,  Kerry Louise Tyson

IPC: C07K16/24 ,  A61K9/00 ,  A61K39/395

CPC classification number: C07K16/244 ,  A61K9/0078 ,  A61K39/395 ,  A61K39/3955 ,  A61K2039/505 ,  A61K2039/544 ,  C07K2317/24 ,  C07K2317/33 ,  C07K2317/51 ,  C07K2317/515 ,  C07K2317/55 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/76 ,  C07K2317/92 ,  C07K2317/94

Abstract: The invention relates to antibody molecules having specificity for antigenic determinants of human IL-13, therapeutic uses of the antibody molecules and methods for producing said antibody molecules.

Abstract translation: 本发明涉及对人IL-13的抗原决定簇具有特异性的抗体分子，抗体分子的治疗用途以及产生所述抗体分子的方法。

公开(公告)号：US10233243B2

公开(公告)日：2019-03-19

申请号：US14400812

申请日：2013-05-13

Applicant: UCB Biopharma SPRL

Inventor： Helene Margaret Finney ,  Alastair David Griffiths Lawson ,  Stevan Graham Shaw ,  Bryan John Smith ,  Kerry Louise Tyson ,  Lara Kevorkian ,  Christoph Meier ,  Kaushik Sarkar ,  Paul Alan Atherfold

IPC: C07K16/00 ,  C12P21/08 ,  A61K39/395 ,  C07K16/28 ,  G01N33/50 ,  G01N33/564 ,  G01N33/68 ,  A61K47/60 ,  A61K47/64 ,  C07K1/00 ,  A61K39/00

Abstract: The disclosure relates to antibodies specific to FcRn, formulations comprising the same, use of each in therapy, processes for expressing and optionally formulating said antibody, DNA encoding the antibodies and hosts comprising said DNA.

公开(公告)号：US11384148B2

公开(公告)日：2022-07-12

申请号：US16271086

申请日：2019-02-08

Applicant: UCB Biopharma SPRL

Inventor： Helene Margaret Finney ,  Alastair David Griffiths Lawson ,  Stevan Graham Shaw ,  Bryan John Smith ,  Kerry Louise Tyson ,  Lara Kevorkian ,  Christoph Meier ,  Kaushik Sarkar ,  Paul Alan Atherfold

IPC: A61K39/395 ,  A61K39/40 ,  C07K16/28 ,  G01N33/50 ,  G01N33/564 ,  G01N33/68 ,  A61K47/60 ,  A61K47/64 ,  C07K16/00 ,  A61K39/00

Abstract: The disclosure relates to antibodies specific to FcRn, formulations comprising the same, use of each in therapy, processes for expressing and optionally formulating said antibody, DNA encoding the antibodies and hosts comprising said DNA.

公开(公告)号：US11352414B2

公开(公告)日：2022-06-07

申请号：US15123038

申请日：2015-03-05

Applicant: UCB BIOPHARMA SPRL

Inventor： Farnaz Fallah-Arani ,  Robert Anthony Griffin ,  David Paul Humphreys ,  Shirley Jane Peters ,  Bryan John Smith ,  Paul Edward Stephens

IPC: C07K1/00 ,  A61K39/00 ,  C07K16/00 ,  C07K16/46 ,  C12N15/62 ,  C12P21/02

Abstract: The invention relates to multimeric fusion proteins which bind to human Fc receptors. The invention also relates to therapeutic compositions comprising the proteins, and their use in the treatment of immune disorders.

公开(公告)号：US11220547B2

公开(公告)日：2022-01-11

申请号：US16299407

申请日：2019-03-12

Applicant: UCB BIOPHARMA SPRL

Inventor： Paul Alan Atherfold ,  Thomas Allen Ceska ,  Helene Margaret Finney ,  Lara Kevorkian ,  Kaushik Sarkar ,  Bryan John Smith ,  Kerry Louise Tyson

IPC: C07H21/02 ,  C07H21/04 ,  C12P21/06 ,  C12P21/04 ,  C12N5/00 ,  C12N5/16 ,  C12N1/20 ,  C07K16/28 ,  A61K47/60 ,  A61K47/68 ,  C07K16/00 ,  A61K39/00

Abstract: The disclosure relates to antibodies specific to FcRn, formulations comprising the same, use of each in therapy, processes for expressing and optionally formulating said antibody, DNA encoding the antibodies and hosts comprising said DNA.

公开(公告)号：US20190248890A1

公开(公告)日：2019-08-15

申请号：US16271086

申请日：2019-02-08

Applicant: UCB Biopharma SPRL

Inventor： Helene Margaret Finney ,  Alastair David Griffiths Lawson ,  Stevan Graham Shaw ,  Bryan John Smith ,  Kerry Louise Tyson ,  Lara Kevorkian ,  Christoph Meier ,  Kaushik Sarkar ,  Paul Alan Atherfold

IPC: C07K16/28 ,  A61K39/395 ,  A61K47/64 ,  G01N33/50 ,  G01N33/564 ,  G01N33/68 ,  A61K47/60

CPC classification number: C07K16/283 ,  A61K39/3955 ,  A61K47/60 ,  A61K47/643 ,  A61K2039/505 ,  C07K2317/21 ,  C07K2317/24 ,  C07K2317/33 ,  C07K2317/55 ,  C07K2317/565 ,  C07K2317/76 ,  C07K2317/92 ,  G01N33/5047 ,  G01N33/564 ,  G01N33/6854 ,  G01N33/6857 ,  G01N33/6893 ,  G01N2333/70535 ,  G01N2500/02 ,  G01N2500/10 ,  G01N2800/104 ,  G01N2800/24 ,  G01N2800/28

Abstract: The disclosure relates to antibodies specific to FcRn, formulations comprising the same, use of each in therapy, processes for expressing and optionally formulating said antibody, DNA encoding the antibodies and hosts comprising said DNA.

公开(公告)号：US10273302B2

公开(公告)日：2019-04-30

申请号：US15036209

申请日：2014-11-12

Applicant: UCB BIOPHARMA SPRL

Inventor： Paul Alan Atherfold ,  Thomas Allen Ceska ,  Helene Margaret Finney ,  Lara Kevorkian ,  Kaushik Sarkar ,  Bryan John Smith ,  Kerry Louise Tyson

IPC: C07K16/00 ,  C12P21/08 ,  A61K39/395 ,  A61K39/40 ,  C07K16/28 ,  A61K47/60 ,  A61K47/68 ,  A61K39/00

Abstract: The disclosure relates to antibodies specific to FcRn, formulations comprising the same, use of each in therapy, processes for expressing and optionally formulating said antibody, DNA encoding the antibodies and hosts comprising said DNA.