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公开(公告)号：US20150118240A1
公开(公告)日：2015-04-30
申请号：US14400812
申请日：2013-05-13
申请人： UCB Biopharma SPRL
发明人： Helene Margaret Finney , Alastair David Griffiths Lawson , Stevan Graham Shaw , Bryan John Smith , Kerry Louise Tyson , Lara Kevorkian , Christoph Meier , Kaushik Sarkar , Paul Alan Atherfold
IPC分类号： C07K16/28 , G01N33/50 , G01N33/68 , A61K47/48 , A61K39/395
CPC分类号： C07K16/283 , A61K39/3955 , A61K47/60 , A61K47/643 , A61K2039/505 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/55 , C07K2317/565 , C07K2317/76 , C07K2317/92 , G01N33/5047 , G01N33/564 , G01N33/6854 , G01N33/6857 , G01N33/6893 , G01N2333/70535 , G01N2500/02 , G01N2500/10 , G01N2800/104 , G01N2800/24 , G01N2800/28
摘要： The disclosure relates to antibodies specific to FcRn, formulations comprising the same, use of each in therapy, processes for expressing and optionally formulating said antibody, DNA encoding the antibodies and hosts comprising said DNA.
摘要翻译： 本公开涉及对FcRn特异性的抗体，包含其的制剂，治疗中的每一种的使用，用于表达和任选配制所述抗体的方法，编码抗体的DNA和包含所述DNA的宿主。
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公开(公告)号：US11384148B2
公开(公告)日：2022-07-12
申请号：US16271086
申请日：2019-02-08
申请人： UCB Biopharma SPRL
发明人： Helene Margaret Finney , Alastair David Griffiths Lawson , Stevan Graham Shaw , Bryan John Smith , Kerry Louise Tyson , Lara Kevorkian , Christoph Meier , Kaushik Sarkar , Paul Alan Atherfold
IPC分类号： A61K39/395 , A61K39/40 , C07K16/28 , G01N33/50 , G01N33/564 , G01N33/68 , A61K47/60 , A61K47/64 , C07K16/00 , A61K39/00
摘要： The disclosure relates to antibodies specific to FcRn, formulations comprising the same, use of each in therapy, processes for expressing and optionally formulating said antibody, DNA encoding the antibodies and hosts comprising said DNA.
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公开(公告)号：US10233243B2
公开(公告)日：2019-03-19
申请号：US14400812
申请日：2013-05-13
申请人： UCB Biopharma SPRL
发明人： Helene Margaret Finney , Alastair David Griffiths Lawson , Stevan Graham Shaw , Bryan John Smith , Kerry Louise Tyson , Lara Kevorkian , Christoph Meier , Kaushik Sarkar , Paul Alan Atherfold
IPC分类号： C07K16/00 , C12P21/08 , A61K39/395 , C07K16/28 , G01N33/50 , G01N33/564 , G01N33/68 , A61K47/60 , A61K47/64 , C07K1/00 , A61K39/00
摘要： The disclosure relates to antibodies specific to FcRn, formulations comprising the same, use of each in therapy, processes for expressing and optionally formulating said antibody, DNA encoding the antibodies and hosts comprising said DNA.
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公开(公告)号：US11220547B2
公开(公告)日：2022-01-11
申请号：US16299407
申请日：2019-03-12
申请人： UCB BIOPHARMA SPRL
发明人： Paul Alan Atherfold , Thomas Allen Ceska , Helene Margaret Finney , Lara Kevorkian , Kaushik Sarkar , Bryan John Smith , Kerry Louise Tyson
IPC分类号： C07H21/02 , C07H21/04 , C12P21/06 , C12P21/04 , C12N5/00 , C12N5/16 , C12N1/20 , C07K16/28 , A61K47/60 , A61K47/68 , C07K16/00 , A61K39/00
摘要： The disclosure relates to antibodies specific to FcRn, formulations comprising the same, use of each in therapy, processes for expressing and optionally formulating said antibody, DNA encoding the antibodies and hosts comprising said DNA.
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公开(公告)号：US10766956B2
公开(公告)日：2020-09-08
申请号：US16307444
申请日：2017-06-07
申请人： UCB BIOPHARMA SPRL
发明人： Helene Bon , Joanne Elizabeth Compson , Kate Louise Dixon , Carl Brendan Doyle , Mark Ellis , Maria Margarida Gouveia Sancho , Raymond Anthony Jupp , Lara Kevorkian , Daniel John Lightwood , Diane Marshall , Andrew Charles Payne , Joseph Michael David Rastrick , Monika-Sarah Schulze , Alison Turner , Kerry Louise Tyson
IPC分类号： C07K16/22 , A61P11/00 , A61K9/00 , A61P11/12 , A61K39/395
摘要： The present disclosure relates to TGF-beta antibodies and binding fragments thereof, DNA encoding the same, host cells comprising said DNA and methods of expressing the antibody or binding fragment in a host cell. The disclosure also extends to pharmaceutical compositions comprising the antibody or a binding fragment thereof and use of the antibody, binding fragment and compositions comprising the same in treatment of various diseases including fibrosis.
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公开(公告)号：US20190248890A1
公开(公告)日：2019-08-15
申请号：US16271086
申请日：2019-02-08
申请人： UCB Biopharma SPRL
发明人： Helene Margaret Finney , Alastair David Griffiths Lawson , Stevan Graham Shaw , Bryan John Smith , Kerry Louise Tyson , Lara Kevorkian , Christoph Meier , Kaushik Sarkar , Paul Alan Atherfold
IPC分类号： C07K16/28 , A61K39/395 , A61K47/64 , G01N33/50 , G01N33/564 , G01N33/68 , A61K47/60
CPC分类号： C07K16/283 , A61K39/3955 , A61K47/60 , A61K47/643 , A61K2039/505 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/55 , C07K2317/565 , C07K2317/76 , C07K2317/92 , G01N33/5047 , G01N33/564 , G01N33/6854 , G01N33/6857 , G01N33/6893 , G01N2333/70535 , G01N2500/02 , G01N2500/10 , G01N2800/104 , G01N2800/24 , G01N2800/28
摘要： The disclosure relates to antibodies specific to FcRn, formulations comprising the same, use of each in therapy, processes for expressing and optionally formulating said antibody, DNA encoding the antibodies and hosts comprising said DNA.
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公开(公告)号：US10273302B2
公开(公告)日：2019-04-30
申请号：US15036209
申请日：2014-11-12
申请人： UCB BIOPHARMA SPRL
发明人： Paul Alan Atherfold , Thomas Allen Ceska , Helene Margaret Finney , Lara Kevorkian , Kaushik Sarkar , Bryan John Smith , Kerry Louise Tyson
IPC分类号： C07K16/00 , C12P21/08 , A61K39/395 , A61K39/40 , C07K16/28 , A61K47/60 , A61K47/68 , A61K39/00
摘要： The disclosure relates to antibodies specific to FcRn, formulations comprising the same, use of each in therapy, processes for expressing and optionally formulating said antibody, DNA encoding the antibodies and hosts comprising said DNA.
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