公开(公告)号：US11911626B2

公开(公告)日：2024-02-27

申请号：US17212370

申请日：2021-03-25

Applicant: UNIVERSITY OF KANSAS

Inventor： Elizabeth Annamaria Friis ,  John Patrick Domann ,  Paul M. Arnold

IPC: A61N1/378 ,  H02N2/18 ,  H10N30/02 ,  H10N30/30 ,  H10N30/50 ,  H10N30/057 ,  H10N30/88 ,  H10N30/092 ,  H10N30/80 ,  H10N30/85 ,  H10N30/87 ,  A61F2/44 ,  A61N1/20 ,  A61N1/05 ,  A61N1/32 ,  A61F2/28

CPC classification number: A61N1/378 ,  A61F2/4455 ,  A61N1/20 ,  A61N1/3785 ,  H02N2/181 ,  H10N30/02 ,  H10N30/057 ,  H10N30/092 ,  H10N30/30 ,  H10N30/50 ,  H10N30/505 ,  H10N30/506 ,  H10N30/802 ,  H10N30/852 ,  H10N30/875 ,  H10N30/88 ,  A61F2002/2821 ,  A61N1/056 ,  A61N1/0529 ,  A61N1/0551 ,  A61N1/205 ,  A61N1/326

Abstract: The present application relates to stacked piezoelectric composites comprising piezoelectric structures. Suitably, the composites are useful as tissue-stimulating implants, including spinal fusion implants. The present application also relates to methods of making stacked piezoelectric composites.

公开(公告)号：US12120959B2

公开(公告)日：2024-10-15

申请号：US17045262

申请日：2019-04-02

Applicant: UNIVERSITY OF KANSAS ,  EVOKE MEDICAL, LLC

Inventor： Elizabeth Annamaria Friis ,  Ember Krech ,  Eileen Cadel ,  Bonnie Reinsch ,  Leighton Lapierre

IPC: H10N30/50 ,  H10N30/30 ,  H10N30/853 ,  H10N30/857 ,  A61N1/05

CPC classification number: H10N30/50 ,  H10N30/30 ,  H10N30/8536 ,  H10N30/8554 ,  H10N30/857 ,  A61N1/0551

Abstract: The present application relates to stacked piezoelectric energy harvesters that include compliant layers between piezoelectric layers. The energy harvesters are useful in various structures and devices, including tissue-stimulating implants, such as spinal fusion implants. The present application also relates to methods of increasing the power output of a piezoelectric energy harvester through the inclusion of compliant layers.

公开(公告)号：US10960218B2

公开(公告)日：2021-03-30

申请号：US15766535

申请日：2016-10-05

Applicant: University of Kansas

Inventor： Elizabeth Annamaria Friis ,  John Patrick Domann ,  Paul M. Arnold

IPC: A61N1/378 ,  H01L41/04 ,  H01L41/047 ,  H01L41/053 ,  H01L41/083 ,  H01L41/18 ,  H01L41/23 ,  H01L41/277 ,  H01L41/37 ,  A61N1/20 ,  H02N2/18 ,  H01L41/113 ,  A61F2/44 ,  A61N1/05 ,  A61N1/32 ,  A61F2/28

Abstract: The present application relates to stacked piezoelectric composites comprising piezoelectric structures. Suitably, the composites are useful as tissue-stimulating implants, including spinal fusion implants. The present application also relates to methods of making stacked piezoelectric composites.

公开(公告)号：US20150134061A1

公开(公告)日：2015-05-14

申请号：US14407636

申请日：2013-06-11

Applicant: University of Kansas

Inventor： Elizabeth Annamaria Friis ,  John Patrick Domann

IPC: A61F2/30 ,  A61L27/44 ,  B29C71/00 ,  B29C47/00 ,  B29C43/00 ,  B29C49/00 ,  B29C51/00 ,  A61F2/44 ,  B29C45/00

CPC classification number: A61F2/30771 ,  A61F2/4455 ,  A61F2002/2821 ,  A61F2002/30087 ,  A61F2002/3093 ,  A61L27/446 ,  A61L27/50 ,  A61L2430/38 ,  B29C43/003 ,  B29C45/0001 ,  B29C48/022 ,  B29C49/0005 ,  B29C51/002 ,  B29C71/0072 ,  B29C2049/001 ,  B29K2301/00 ,  B29L2031/7532 ,  H01L41/183 ,  H01L41/257 ,  H01L41/37

Abstract: There is a need for methods that can produce piezoelectric composites having suitable physical characteristics and also optimized electrical stimulatory properties. The present application provides piezoelectric composites, including tissue-stimulating composites, as well as methods of making such composites, that meet these needs. In embodiments, methods of making a spinal implant are provided. The methods suitably comprise preparing a thermoset, thermoplastic or thermoset/thermoplastic, or copolymer polymerizable matrix, dispersing a plurality of piezoelectric particles in the polymerizable matrix to generate dispersion, shaping the dispersion, inducing an electric polarization in the piezoelectric particles in the shaped dispersion, wherein at least 40% of the piezoelectric particles form chains.

Abstract translation: 需要能够生产具有合适的物理特性和优化的电刺激性能的压电复合材料的方法。 本申请提供了压电复合材料，包括组织刺激复合物，以及制备这种复合材料的方法，以满足这些需要。 在实施例中，提供了制造脊柱植入物的方法。 所述方法适合包括制备热固性，热塑性或热固性/热塑性或共聚物可聚合基质，将多个压电颗粒分散在可聚合基质中以产生分散体，使分散体成形，在成型分散体中的压电颗粒中引起电极化， 其中至少40％的压电颗粒形成链。