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公开(公告)号:US11198643B2
公开(公告)日:2021-12-14
申请号:US16270735
申请日:2019-02-08
申请人: UNIVERSITY OF LEEDS
发明人: Gin Jose , Toney Teddy Fernandez , Peter John Grant , Animesh Jha , Sikha Saha , David Paul Steenson
IPC分类号: C03C23/00 , C03C3/04 , A61B1/00 , C23C14/48 , A61B5/1455 , C23C14/28 , C23C14/32 , C23C14/22 , G02B6/12
摘要: The present invention relates to a substrate comprising an ion-implanted layer, for example a cation, wherein the ion implanted layer has a substantially uniform distribution of the implanted ions at a significantly greater depth than previously possible, to a well-defined and sharp boundary within the substrate. The invention further comprises said substrate wherein the substrate is a silicon based substrate, such as glass. The invention also comprises the use of said material as a waveguide and the use of said material in measurement devices.
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公开(公告)号:US10080811B2
公开(公告)日:2018-09-25
申请号:US14382728
申请日:2013-03-07
申请人: University of Leeds
发明人: Sikha Saha , Gin Jose , Animesh Jha
IPC分类号: A61B5/1455 , A61K49/00 , A61B5/00 , A61K47/52
CPC分类号: A61K49/0019 , A61B5/0059 , A61B5/0071 , A61B5/0075 , A61B5/0077 , A61B5/14546 , A61B5/1455 , A61B2560/0223 , A61K47/52 , A61K49/0004
摘要: The present Invention relates to the monitoring of biological substances, such as non-invasive monitoring of such substances in animal, for examples biomarkers and metabolites. Specifically, the invention further relates to such monitoring using rare earth tagged marker compounds. The invention further relates to such monitoring using laser spectroscopy or Raman spectroscopy. The invention further relates to the use of such monitoring in disease states, such as stroke, neurological disorders and cardiovascular disorders. The invention further relates to novel rare-earth conjugated marker compounds and processes for preparing said rare-earth conjugated compounds
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公开(公告)号:US20190256413A1
公开(公告)日:2019-08-22
申请号:US16270735
申请日:2019-02-08
申请人: UNIVERSITY OF LEEDS
发明人: Gin Jose , Toney Teddy Fernandez , Peter John Grant , Animesh Jha , Sikha Saha , David Paul Steenson
IPC分类号: C03C23/00 , C23C14/48 , A61B5/1455 , C03C3/04
摘要: The present invention relates to a substrate comprising an ion-implanted layer, for example a cation, wherein the ion implanted layer has a substantially uniform distribution of the implanted ions at a significantly greater depth than previously possible, to a well-defined and sharp boundary within the substrate. The invention further comprises said substrate wherein the substrate is a silicon based substrate, such as glass. The invention also comprises the use of said material as a waveguide and the use of said material in measurement devices.
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公开(公告)号:US10604445B2
公开(公告)日:2020-03-31
申请号:US14377403
申请日:2013-02-08
申请人: UNIVERSITY OF LEEDS
发明人: Gin Jose , Toney Teddy Fernandez , Peter John Grant , Animesh Jha , Sikha Saha , David Paul Steenson
IPC分类号: C23C14/32 , C03C23/00 , C03C3/04 , C23C14/48 , A61B5/1455 , C23C14/28 , C23C14/22 , G02B6/12
摘要: The present invention relates to a substrate comprising an ion-implanted layer, for example a cation, wherein the ion implanted layer has a substantially uniform distribution of the implanted ions at a significantly greater depth than previously possible, to a well-defined and sharp boundary within the substrate. The invention further comprises said sub-strate wherein the substrate is a silicon based substrate, such as glass. The invention also comprises the use of said material as a waveguide and the use of said material in measurement devices.
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公开(公告)号:US20150353419A1
公开(公告)日:2015-12-10
申请号:US14377403
申请日:2013-02-08
申请人: UNIVERSITY OF LEEDS
发明人: Gin Jose , Toney Teddy Fernandez , Peter John Grant , Animesh Jha , Sikha Saha , David Paul Steenson
IPC分类号: C03C23/00 , C23C14/48 , A61B5/1455 , C03C3/04
CPC分类号: C03C23/0055 , A61B5/1455 , C03C3/04 , C23C14/48 , G02B2006/12061 , G02B2006/12188 , Y10T428/31 , Y10T428/315
摘要: The present invention relates to a substrate comprising an ion-implanted layer, for example a cation, wherein the ion implanted layer has a uniform distribution of the implanted ions at a significantly greater depth than previously possible. The invention further comprises said substrate wherein the substrate is a silicon based substrate, such as glass. The invention also comprises the use of said material as a waveguide and the use of said material in measurement devices.
摘要翻译: 本发明涉及一种包括离子注入层(例如阳离子)的衬底,其中离子注入层具有比先前可能的更大深度的注入离子的均匀分布。 本发明还包括所述衬底,其中衬底是硅基衬底,例如玻璃。 本发明还包括使用所述材料作为波导和所述材料在测量装置中的用途。
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公开(公告)号:US20150132507A1
公开(公告)日:2015-05-14
申请号:US14601000
申请日:2015-01-20
申请人: University Of Leeds
发明人: Gin Jose , Animesh Jha , David Paul Steenson
IPC分类号: B23K26/38
CPC分类号: B23K26/38 , C03C3/122 , C03C2218/15 , H01S3/0632 , H01S3/08 , H01S3/1608 , H01S3/177
摘要: A process for fabricating a device capable of random lasing comprising a substrate and a rare earth-doped glass fabricated on the substrate in the form of a waveguide, wherein the glass comprises a germanium glass, a titanium glass or a chalcogenide glass, where the process comprises ablating a target glass with incident radiation from an ultrafast laser in the presence of the substrate to deposit a quantity of the target glass on the substrate and applying rastering to ablate the target glass uniformly. The ultrafast laser emits pulses of 15 ps or less and the relative position of the laser spot on the target glass with respect to the substrate is constant during the ablation and wherein the Gaussian intensity profile of the laser beam has a spot area less than 3000 μm2.
摘要翻译: 一种用于制造能够随机激光的装置的方法,其包括以波导形式在基板上制造的基板和稀土掺杂玻璃,其中所述玻璃包括锗玻璃,钛玻璃或硫族化物玻璃,其中所述方法 包括在存在基底的情况下从超快激光的入射辐射烧蚀靶玻璃,以将一定数量的靶玻璃沉积在基底上,并进行扫描以均匀地烧蚀靶玻璃。 超快激光发射15ps以下的脉冲,并且激光束相对于基板在靶玻璃上的相对位置在消融期间是恒定的,并且其中激光束的高斯强度分布具有小于3000μm2的斑点面积 。
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公开(公告)号:US20200239362A1
公开(公告)日:2020-07-30
申请号:US16822468
申请日:2020-03-18
申请人: UNIVERSITY OF LEEDS
发明人: Gin Jose , Toney Teddy Fernandez , Peter John Grant , Animesh Jha , Sikha Saha , David Paul Steenson
IPC分类号: C03C23/00 , C03C3/04 , C23C14/32 , C23C14/48 , C23C14/22 , A61B5/1455 , C23C14/28 , G02B6/12
摘要: The present invention relates to a substrate comprising an ion-implanted layer, for example a cation, wherein the ion implanted layer has a substantially uniform distribution of the implanted ions at a significantly greater depth than previously possible, to a well-defined and sharp boundary within the substrate. The invention further comprises said substrate wherein the substrate is a silicon based substrate, such as glass. The invention also comprises the use of said material as a waveguide and the use of said material in measurement devices.
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公开(公告)号:US20170297958A9
公开(公告)日:2017-10-19
申请号:US14377403
申请日:2013-02-08
申请人: UNIVERSITY OF LEEDS
发明人: Gin Jose , Toney Teddy Fernandez , Peter John Grant , Animesh Jha , Sikha Saha , David Paul Steenson
IPC分类号: C03C23/00 , A61B5/1455 , C03C3/04 , C23C14/48 , G02B6/12
CPC分类号: C03C23/0055 , A61B5/1455 , C03C3/04 , C23C14/48 , G02B2006/12061 , G02B2006/12188 , Y10T428/31 , Y10T428/315
摘要: The present invention relates to a substrate comprising an ion-implanted layer, for example a cation, wherein the ion implanted layer has a uniform distribution of the implanted ions at a significantly greater depth than previously possible. The invention further comprises said substrate wherein the substrate is a silicon based substrate, such as glass. The invention also comprises the use of said material as a waveguide and the use of said material in measurement devices.
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公开(公告)号:US20170152174A9
公开(公告)日:2017-06-01
申请号:US14377403
申请日:2013-02-08
申请人: UNIVERSITY OF LEEDS
发明人: Gin Jose , Toney Teddy Fernandez , Peter John Grant , Animesh Jha , Sikha Saha , David Paul Steenson
IPC分类号: C03C23/00 , C23C14/48 , A61B5/1455 , C03C3/04
CPC分类号: C03C23/0055 , A61B5/1455 , C03C3/04 , C23C14/48 , G02B2006/12061 , G02B2006/12188 , Y10T428/31 , Y10T428/315
摘要: The present invention relates to a substrate comprising an ion-implanted layer, for example a cation, wherein the ion implanted layer has a uniform distribution of the implanted ions at a significantly greater depth than previously possible. The invention further comprises said substrate wherein the substrate is a silicon based substrate, such as glass. The invention also comprises the use of said material as a waveguide and the use of said material in measurement devices.
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公开(公告)号:US20150045664A1
公开(公告)日:2015-02-12
申请号:US14382728
申请日:2013-03-07
申请人: UNIVERSITY OF LEEDS
发明人: Sikha Saha , Gin Jose , Animesh Jha
CPC分类号: A61K49/0019 , A61B5/0059 , A61B5/0071 , A61B5/0075 , A61B5/0077 , A61B5/14546 , A61B5/1455 , A61B2560/0223 , A61K47/52 , A61K49/0004
摘要: The present Invention relates to the monitoring of biological substances, such as non-invasive monitoring of such substances in animal, for examples biomarkers and metabolites. Specifically, the invention further relates to such monitoring using rare earth tagged marker compounds. The invention further relates to such monitoring using laser spectroscopy or Raman spectroscopy. The invention further relates to the use of such monitoring in disease states, such as stroke, neurological disorders and cardiovascular disorders. The invention further relates to novel rare-earth conjugated marker compounds and processes for preparing said rare-earth conjugated compounds
摘要翻译: 本发明涉及生物物质的监测,例如动物中这种物质的非侵入性监测,例如生物标志物和代谢物。 具体地,本发明进一步涉及使用稀土标记标记化合物的这种监测。 本发明还涉及使用激光光谱学或拉曼光谱学的这种监测。 本发明还涉及在诸如中风,神经障碍和心血管疾病的疾病状态中使用这种监测。 本发明还涉及新型稀土共轭标记化合物和制备所述稀土共轭化合物的方法
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